Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder : Nature Neuroscience : Nature Research

Each boxplot corresponds to the distribution of the AUC obtained from 50 evaluations (10 five-fold cross-validation; ends and center line: 25th, 50th and 75th percentiles of AUC, respectively; notches: 95% confidence interval around the median; whiskers: 1.5 interquartile range above and below the 25th and 75th percentiles; dots: outliers). Evidence-weighted classifier (purple) significantly outperforms all the other classifiers (Wilcoxon rank-sum test, U 2,399, P 1 10 14). Enrichment P-values atop each bar were calculated using a permutation test (Online Methods). Fractions of genes in the gene set (y axis) that occurred within each decile of the genome-wide ranking (x axis; first decile colored red; number of genes in top decile/total and enrichment P-value in parentheses).