Detecting Diabetic Nephropathy with AI - Vanderbilt Discover

Diabetic nephropathy (DN) is defined by elevated urine albumin excretion or reduced glomerular filtration rate (GFR), or both. While DN may be diagnosed clinically, pathology is often needed to confirm the diagnosis and establish the severity of the injury. "In addition to making the correct diagnosis of diabetic nephropathy, we want to be able to assess the severity of the injury." Pathologists usually classify DN based on a visual assessment of glomerular pathology using immunofluorescence microscopy and electron microscopy. Although diagnostic guidelines have been well established, scoring of severity of the lesions may vary among pathologists.