AI Distinguishes Cancer Cells From Healthy Ones

When it comes to identifying patterns in mountains of data, human beings are no match for artificial intelligence (AI). In particular, a branch of AI called machine learning is often used to find regularities in data sets – be it for stock market analysis, image and speech recognition, or the classification of cells. To reliably distinguish cancer cells from healthy cells, a team led by Dr. Altuna Akalin, head of the Bioinformatics and Omics Data Science Platform at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), has now developed a machine learning program called "ikarus." The program found a pattern in tumor cells that is common to different types of cancer, consisting of a characteristic combination of genes. According to the team's paper in the journal Genome Biology, the algorithm also detected types of genes in the pattern that had never been clearly linked to cancer before.