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This book is a collection of many of the seminal papers from the first decade of research in artificial intelligence in medicine (AIM). The editors state that the need for such a collection became evident when a two-day AIM tutorial was held at Stanford in 1980, following the annual national AIM research workshop. The 19 papers included in the book are each introduced by a short section written by the editors. Typically one page in length, these introductory sections are designed to place the paper into context in the field. In addition, the editors have included introductory and concluding chapters of their own.