Reviews: Gradients of Generative Models for Improved Discriminative Analysis of Tandem Mass Spectra

This paper introduces Theseus, an algorithm for matching MS/MS spectra to peptide in a D.B. This is a challenging and important task. It is important because MS/MS is currently practically the only common high-throughput method to identify which proteins are present in a sample. It is challenging because the data is analog (intensity vs. m/z graphs) and extremely noisy. This work builds upon an impressive body of work that has been dedicated to this problem.