A Probabilistic U-Net for Segmentation of Ambiguous Images

Kohl, Simon, Romera-Paredes, Bernardino, Meyer, Clemens, Fauw, Jeffrey De, Ledsam, Joseph R., Maier-Hein, Klaus, Eslami, S. M. Ali, Rezende, Danilo Jimenez, Ronneberger, Olaf

Neural Information Processing Systems 

Many real-world vision problems suffer from inherent ambiguities. In clinical applications for example, it might not be clear from a CT scan alone which particular region is cancer tissue. Therefore a group of graders typically produces a set of diverse but plausible segmentations. We consider the task of learning a distribution over segmentations given an input. To this end we propose a generative segmentation model based on a combination of a U-Net with a conditional variational autoencoder that is capable of efficiently producing an unlimited number of plausible hypotheses.