Combining neuropharmacological experiments with computational modeling, we have shown that cholinergic modulation may enhance associative memory function in piriform (olfactory) cortex. We have shown that the acetylcholine analogue carbachol selectively suppresses synaptic transmission between cells within piriform cortex, while leaving input connections unaffected. When tested in a computational model of piriform cortex, this selective suppression, applied during learning, enhances associative memory performance.

The Hopfield network (Hopfield, 1982,1984) provides a simple model of an associative memory in a neuronal structure. This model, however, is based on highly artificial assumptions, especially the use of formal-two state neurons (Hopfield, 1982) or graded-response neurons (Hopfield, 1984).

Combining neuropharmacological experiments with computational modeling, we have shown that cholinergic modulation may enhance associative memory function in piriform (olfactory) cortex. We have shown that the acetylcholine analogue carbachol selectively suppresses synaptic transmission between cells within piriform cortex, while leaving input connections unaffected. When tested in a computational model of piriform cortex, this selective suppression, applied during learning, enhances associative memory performance.

The Hopfield network (Hopfield, 1982,1984) provides a simple model of an associative memory in a neuronal structure. This model, however, is based on highly artificial assumptions, especially the use of formal-two state neurons (Hopfield,1982) or graded-response neurons (Hopfield, 1984).

James M. Bower Computation and Neural Systems Caltech 216-76 Pasadena, CA 91125 Combining neuropharmacological experiments with computational modeling, wehave shown that cholinergic modulation may enhance associative memory function in piriform (olfactory) cortex. We have shown that the acetylcholine analogue carbachol selectively suppresses synaptic transmission betweencells within piriform cortex, while leaving input connections unaffected. When tested in a computational model of piriform cortex, this selective suppression, applied during learning, enhances associative memory performance.

In Lifschitz, V. (Ed.), Artificial Intelligence and Mathematical Theory of Computation: Papers in Honor of John McCarthy, pp. 359–380. Academic Press.

In this paper we describe the VLSI design and testing of a high capacity associative memory which we call the exponential correlation 3J.'-CMOSassociative memory (ECAM). The prototype programmable chip is capable of storing 32 memory patterns of 24 bits each. The high capacity of the ECAM is partly due to the use of special exponentiation neurons, which are implemented via MOS transistors in this design. The prototype chipsub-threshold of performing one associative recall in 3 J.'S.is capable 1 ARCHITECTURE Previously (Chiueh, 1989), we have proposed a general model for correlation-based associative memories, which includes a variant of the Hopfield memory and highorder correlation memories as special cases. This new exponential correlation associative (ECAM) possesses a very large storage capacity, which scalesmemory exponentially with the length of memory patterns (Chiueh, 1988).

In this paper we describe the VLSI design and testing of a high capacity associative memory which we call the exponential correlation associative memory (ECAM). The prototype 3J.'-CMOS programmable chip is capable of storing 32 memory patterns of 24 bits each. The high capacity of the ECAM is partly due to the use of special exponentiation neurons, which are implemented via sub-threshold MOS transistors in this design. The prototype chip is capable of performing one associative recall in 3 J.'S.

ABSTRACT The CHAC storage scheme has been used as a basis for a software implementation of an associative .emory A major disadvantage of this CHAC-concept is that the degree of local generalization (area of interpolation) is fixed. This paper deals with an algorithm for self-organizing variable generalization for the AKS, based on ideas of T. Kohonen. 1 INTRODUCTION For several years research at the Department of Control Theory and Robotics at the Technical University of Darmstadt has been concerned with the design of a learning real-time control loop with neuron-like associative memories (LERNAS) A Self-organizing Associative Memory System for Control Applications 333 for the control of unknown, nonlinear processes (Ersue, Tolle, 1988). This control concept uses an associative memory system AHS, based on the cerebellar cortex model CHAC by Albus (Albus, 1972), for the storage of a predictive nonlinear process model and an appropriate nonlinear control strategy (Figure 1). Figure 1: The learning control loop LERNAS One problem for adjusting the control loop to a process is, however, to find a suitable set of parameters for the associative memory. The parameters in question determine the degree of generalization within the memory and therefore have a direct influence on the number of training steps required to learn the process behaviour. For a good performance of the control loop it· is desirable to have a very small generalization around a given setpoint but to have a large generalization elsewhere.

In this paper we describe the VLSI design and testing of a high capacity associative memory which we call the exponential correlation associative memory (ECAM). The prototype 3J.'-CMOS programmable chip is capable of storing 32 memory patterns of 24 bits each. The high capacity of the ECAM is partly due to the use of special exponentiation neurons, which are implemented via sub-threshold MOS transistors in this design. The prototype chip is capable of performing one associative recall in 3 J.'S.