We investigate a new, convex relaxation of an expectation-maximization (EM) variant that approximates a standard objective while eliminating local minima. First, a cautionary result is presented, showing that any convex relaxation of EM over hidden variables must give trivial results if any dependence on the missing values is retained. Although this appears to be a strong negative outcome, we then demonstrate how the problem can be bypassed by using equivalence relations instead ofvalue assignments over hidden variables. In particular, we develop new algorithms for estimating exponential conditional models that only require equivalence relationinformation over the variable values. This reformulation leads to an exact expression for EM variants in a wide range of problems. We then develop a semidefinite relaxation that yields global training by eliminating local minima.

A general modeling framework is proposed that unifies nonparametric-Bayesian models, topic-models and Bayesian networks. This class of infinite state Bayes nets (ISBN) can be viewed as directed networks of'hierarchical Dirichlet processes' (HDPs) where the domain of the variables can be structured (e.g.

We introduce a hierarchical Bayesian model for the discovery of putative regulators from gene expression data only. The hierarchy incorporates the knowledge that there are just a few regulators that by themselves only regulate a handful of genes. This is implemented through a so-called spike-and-slab prior, a mixture of Gaussians with different widths, with mixing weights from a hierarchical Bernoulli model. For efficient inference we implemented expectation propagation. Running the model on a malaria parasite data set, we found four genes with significant homology to transcription factors in an amoebe, one RNA regulator and three genes of unknown function (out of the top ten genes considered).

In many structured prediction problems, the highest-scoring labeling is hard to compute exactly, leading to the use of approximate inference methods. However, when inference is used in a learning algorithm, a good approximation of the score may not be sufficient. We show in particular that learning can fail even with an approximate inference method with rigorous approximation guarantees. There are two reasons for this. First, approximate methods can effectively reduce the expressivity ofan underlying model by making it impossible to choose parameters that reliably give good predictions. Second, approximations can respond to parameter changes in such a way that standard learning algorithms are misled. In contrast, we give two positive results in the form of learning bounds for the use of LPrelaxed inference in structured perceptron and empirical risk minimization settings. We argue that without understanding combinations of inference and learning, such as these, that are appropriately compatible, learning performance under approximate inference cannot be guaranteed.

Experiments on a collected data have demonstrated the merits of our approach.

We introduce a new Bayesian model for hierarchical clustering based on a prior over trees called Kingman's coalescent. We develop novel greedy and sequential Monte Carlo inferences which operate in a bottom-up agglomerative fashion. We show experimentally the superiority of our algorithms over the state-of-the-art, and demonstrate our approach in document clustering and phylolinguistics.

Web servers on the Internet need to maintain high reliability, but the cause of intermittent failures of web transactions is non-obvious. We use Bayesian inference to diagnose problems with web services. This diagnosis problem is far larger than any previously attempted: it requires inference of 10^4 possible faults from 10^5 observations. Further, such inference must be performed in less than a second. Inference can be done at this speed by combining a variational approximation, a mean-field approximation, and the use of stochastic gradient descent to optimize a variational cost function. We use this fast inference to diagnose a time series of anomalous HTTP requests taken from a real web service. The inference is fast enough to analyze network logs with billions of entries in a matter of hours.

Motivated by stochastic systems in which observed evidence and conditional dependencies betweenstates of the network change over time, and certain quantities of interest (marginal distributions, likelihood estimates etc.) must be updated, we study the problem of adaptive inference in tree-structured Bayesian networks. We describe an algorithm for adaptive inference that handles a broad range of changes to the network and is able to maintain marginal distributions, MAP estimates, and data likelihoods in all expected logarithmic time. We give an implementation of our algorithm and provide experiments that show that the algorithm can yield up to two orders of magnitude speedups on answering queries and responding to dynamic changesover the sum-product algorithm.

The learning of probabilistic models with many hidden variables and nondecomposable dependenciesis an important and challenging problem. In contrast to traditional approaches based on approximate inference in a single intractable model, our approach is to train a set of tractable submodels by encouraging them to agree on the hidden variables. This allows us to capture non-decomposable aspects of the data while still maintaining tractability. We propose an objective function for our approach, derive EMstyle algorithms for parameter estimation, and demonstrate their effectiveness on three challenging real-world learning tasks.

It is becoming increasingly important to learn from a partially-observed random matrix and predict its missing elements. We assume that the entire matrix is a single sample drawn from a matrix-variate t distribution and suggest a matrix-variate t model (MVTM) to predict those missing elements. We show that MVTM generalizes a range of known probabilistic models, and automatically performs model selection to encourage sparse predictive models. Due to the non-conjugacy of its prior, it is difficult to make predictions by computing the mode or mean of the posterior distribution. We suggest an optimization method that sequentially minimizes a convex upper-bound of the log-likelihood, which is very efficient and scalable. The experiments on a toy data and EachMovie dataset show a good predictive accuracy of the model.