This paper presents some ideas and results of using uncertainty management methods in the presence of data in preference to other statistical and machine learning methods. A medical domain is used as a test-bed with data available from a large hospital database system which collects symptom and outcome information about patients. Data is often missing, of many variable types and sample sizes for particular outcomes is not large. Uncertainty management methods are useful for such domains and have the added advantage of allowing for expert modification of belief values originally obtained from data. Methodological considerations for using belief functions on statistical data are dealt with in some detail. Expert opinions are Incorporated at various levels of the project development and results are reported on an application to liver disease diagnosis. Recent results contrasting the use of weights of evidence and logistic regression on another medical domain are also presented.

We show an approach to automated control of machine vision systems based on incremental creation and evaluation of a particular family of influence diagrams that represent hypotheses of imagery interpretation and possible subsequent processing decisions. In our approach, model-based machine vision techniques are integrated with hierarchical Bayesian inference to provide a framework for representing and matching instances of objects and relationships in imagery and for accruing probabilities to rank order conflicting scene interpretations. We extend a result of Tatman and Shachter to show that the sequence of processing decisions derived from evaluating the diagrams at each stage is the same as the sequence that would have been derived by evaluating the final influence diagram that contains all random variables created during the run of the vision system.

It is suggested that an AI inference system should reflect an inference policy that is tailored to the domain of problems to which it is applied -- and furthermore that an inference policy need not conform to any general theory of rational inference or induction. We note, for instance, that Bayesian reasoning about the probabilistic characteristics of an inference domain may result in the specification of an nonBayesian procedure for reasoning within the inference domain. In this paper, the idea of an inference policy is explored in some detail. To support this exploration, the characteristics of some standard and nonstandard inference policies are examined.

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining the issues attendant to using this class of evidence. This paper presents a framework which structures the process of using scientific data from research reports for the purpose of making decisions, using decision analysis as the basis for the structure and using medical research as the general scientific domain. The structure extends the basic influence diagram for updating belief in an object domain parameter of interest by expanding the parameter into four parts: those of the patient, the population, the study sample, and the effective study sample. The structure uses biases to perform the transformation of one parameter into another, so that, for instance, selection biases, in concert with the population parameter, yield the study sample parameter. The influence diagram structure provides decision theoretic justification for practices of good clinical research such as randomized assignment and blindfolding of care providers. The model covers most research designs used in medicine: case-control studies, cohort studies, and controlled clinical trials, and provides an architecture to separate clearly between statistical knowledge and domain knowledge. The proposed general model can be the basis for clinical epidemiological advisory systems, when coupled with heuristic pruning of irrelevant biases; of statistical workstations, when the computational machinery for calculation of posterior distributions is added; and of meta-analytic reviews, when multiple studies may impact on a single population parameter.

In this paper, we will review the process of evidence accumulation in the PSEIKI system for expectation-driven interpretation of images of 3-D scenes. Expectations are presented to PSEIKI as a geometrical hierarchy of abstractions. PSEIKI's job is then to construct abstraction hierarchies in the perceived image taking cues from the abstraction hierarchies in the expectations. The Dempster-Shafer formalism is used for associating belief values with the different possible labels for the constructed abstractions in the perceived image. This system has been used successfully for autonomous navigation of a mobile robot in indoor environments.

We examine a probabilistic model for the diagnosis of multiple diseases. In the model, diseases and findings are represented as binary variables. Also, diseases are marginally independent, features are conditionally independent given disease instances, and diseases interact to produce findings via a noisy OR-gate. An algorithm for computing the posterior probability of each disease, given a set of observed findings, called quickscore, is presented. The time complexity of the algorithm is O(nm-2m+), where n is the number of diseases, m+ is the number of positive findings and m- is the number of negative findings. Although the time complexity of quickscore i5 exponential in the number of positive findings, the algorithm is useful in practice because the number of observed positive findings is usually far less than the number of diseases under consideration. Performance results for quickscore applied to a probabilistic version of Quick Medical Reference (QMR) are provided.

We introduce and analyze the problem of the compilation of decision models from a decision-theoretic perspective. The techniques described allow us to evaluate various configurations of compiled knowledge given the nature of evidential relationships in a domain, the utilities associated with alternative actions, the costs of run-time delays, and the costs of memory. We describe procedures for selecting a subset of the total observations available to be incorporated into a compiled situation-action mapping, in the context of a binary decision with conditional independence of evidence. The methods allow us to incrementally select the best pieces of evidence to add to the set of compiled knowledge in an engineering setting. After presenting several approaches to compilation, we exercise one of the methods to provide insight into the relationship between the distribution over weights of evidence and the preferred degree of compilation.

BPS, the Bayesian Problem Solver, applies probabilistic inference and decision-theoretic control to flexible, resource-constrained problem-solving. This paper focuses on the Bayesian inference mechanism in BPS, and contrasts it with those of traditional heuristic search techniques. By performing sound inference, BPS can outperform traditional techniques with significantly less computational effort. Empirical tests on the Eight Puzzle show that after only a few hundred node expansions, BPS makes better decisions than does the best existing algorithm after several million node expansions

An efficient algorithm is developed that identifies all independencies implied by the topology of a Bayesian network. Its correctness and maximality stems from the soundness and completeness of d-separation with respect to probability theory. The algorithm runs in time O (l E l) where E is the number of edges in the network.

Stochastic simulation approaches perform probabilistic inference in Bayesian networks by estimating the probability of an event based on the frequency that the event occurs in a set of simulation trials. This paper describes the evidence weighting mechanism, for augmenting the logic sampling stochastic simulation algorithm [Henrion, 1986]. Evidence weighting modifies the logic sampling algorithm by weighting each simulation trial by the likelihood of a network's evidence given the sampled state node values for that trial. We also describe an enhancement to the basic algorithm which uses the evidential integration technique [Chin and Cooper, 1987]. A comparison of the basic evidence weighting mechanism with the Markov blanket algorithm [Pearl, 1987], the logic sampling algorithm, and the evidence integration algorithm is presented. The comparison is aided by analyzing the performance of the algorithms in a simple example network.