Airway segmentation is crucial for the examination, diagnosis, and prognosis of lung diseases, while its manual delineation is unduly burdensome. To alleviate this time-consuming and potentially subjective manual procedure, researchers have proposed methods to automatically segment airways from computerized tomography (CT) images. However, some small-sized airway branches (e.g., bronchus and terminal bronchioles) significantly aggravate the difficulty of automatic segmentation by machine learning models. In particular, the variance of voxel values and the severe data imbalance in airway branches make the computational module prone to discontinuous and false-negative predictions. especially for cohorts with different lung diseases. Attention mechanism has shown the capacity to segment complex structures, while fuzzy logic can reduce the uncertainty in feature representations. Therefore, the integration of deep attention networks and fuzzy theory, given by the fuzzy attention layer, should be an escalated solution for better generalization and robustness. This paper presents an efficient method for airway segmentation, comprising a novel fuzzy attention neural network and a comprehensive loss function to enhance the spatial continuity of airway segmentation. The deep fuzzy set is formulated by a set of voxels in the feature map and a learnable Gaussian membership function. Different from the existing attention mechanism, the proposed channel-specific fuzzy attention addresses the issue of heterogeneous features in different channels. Furthermore, a novel evaluation metric is proposed to assess both the continuity and completeness of airway structures. The efficiency, generalization and robustness of the proposed method have been proved by training on normal lung disease while testing on datasets of lung cancer, COVID-19 and pulmonary fibrosis.

In recent years, the Neurosymbolic framework has attracted a lot of attention in various applications, from recommender systems and information retrieval to healthcare and finance. This success is due to its stellar performance combined with attractive properties, such as learning and reasoning. The new emerging Neurosymbolic field is currently experiencing a renaissance, as novel frameworks and algorithms motivated by various practical applications are being introduced, building on top of the classical neural and reasoning problem setting. This article aims to provide a comprehensive review of significant recent developments in real-world applications of Neurosymbolic Artificial Intelligence. Specifically, we introduce a taxonomy of common Neurosymbolic applications and summarize the state-of-the-art for each of those domains. Furthermore, we identify important current trends and provide new perspectives pertaining to the future of this burgeoning field.

This paper presents a novel non-stationary dynamic pricing algorithm design, where pricing agents face incomplete demand information and market environment shifts. The agents run price experiments to learn about each product's demand curve and the profit-maximizing price, while being aware of market environment shifts to avoid high opportunity costs from offering sub-optimal prices. The proposed ACIDP extends information-directed sampling (IDS) algorithms from statistical machine learning to include microeconomic choice theory, with a novel pricing strategy auditing procedure to escape sub-optimal pricing after market environment shift. The proposed ACIDP outperforms competing bandit algorithms including Upper Confidence Bound (UCB) and Thompson sampling (TS) in a series of market environment shifts.

Machine learning methods are increasingly widely used in high-risk settings such as healthcare, transportation, and finance. In these settings, it is important that a model produces calibrated uncertainty to reflect its own confidence and avoid failures. In this paper we survey recent works on uncertainty quantification (UQ) for deep learning, in particular distribution-free Conformal Prediction method for its mathematical properties and wide applicability. We will cover the theoretical guarantees of conformal methods, introduce techniques that improve calibration and efficiency for UQ in the context of spatiotemporal data, and discuss the role of UQ in the context of safe decision making.

We present rectified flow, a surprisingly simple approach to learning (neural) ordinary differential equation (ODE) models to transport between two empirically observed distributions \pi_0 and \pi_1, hence providing a unified solution to generative modeling and domain transfer, among various other tasks involving distribution transport. The idea of rectified flow is to learn the ODE to follow the straight paths connecting the points drawn from \pi_0 and \pi_1 as much as possible. This is achieved by solving a straightforward nonlinear least squares optimization problem, which can be easily scaled to large models without introducing extra parameters beyond standard supervised learning. The straight paths are special and preferred because they are the shortest paths between two points, and can be simulated exactly without time discretization and hence yield computationally efficient models. We show that the procedure of learning a rectified flow from data, called rectification, turns an arbitrary coupling of \pi_0 and \pi_1 to a new deterministic coupling with provably non-increasing convex transport costs. In addition, recursively applying rectification allows us to obtain a sequence of flows with increasingly straight paths, which can be simulated accurately with coarse time discretization in the inference phase. In empirical studies, we show that rectified flow performs superbly on image generation, image-to-image translation, and domain adaptation. In particular, on image generation and translation, our method yields nearly straight flows that give high quality results even with a single Euler discretization step.

Deep Reinforcement Learning uses a deep neural network to encode a policy, which achieves very good performance in a wide range of applications but is widely regarded as a black box model. A more interpretable alternative to deep networks is given by neuro-fuzzy controllers. Unfortunately, neuro-fuzzy controllers often need a large number of rules to solve relatively simple tasks, making them difficult to interpret. In this work, we present an algorithm to distill the policy from a deep Q-network into a compact neuro-fuzzy controller. This allows us to train compact neuro-fuzzy controllers through distillation to solve tasks that they are unable to solve directly, combining the flexibility of deep reinforcement learning and the interpretability of compact rule bases. We demonstrate the algorithm on three well-known environments from OpenAI Gym, where we nearly match the performance of a DQN agent using only 2 to 6 fuzzy rules.

The method is constructed as an analogue of the train/test split in correlation-based machine learning and as an enhancement of current causal validation strategies that are consistent with the logic of scientific discovery. The effectiveness of the method is illustrated using Pearl's sprinkler example, before a thorough simulation-based investigation is conducted. Limits of the technique are identified by studying exemplary failing scenarios, which are furthermore used to propose a list of topics for future research and improvements of the presented version of quantitative probing. The code for integrating quantitative probing into causal analysis, as well as the code for the presented simulation-based studies of the effectiveness of quantitative probing is provided in two separate open-source Python packages.

ISO 14971 is the primary standard used for medical device risk management. While it specifies the requirements for medical device risk management, it does not specify a particular method for performing risk management. Hence, medical device manufacturers are free to develop or use any appropriate methods for managing the risk of medical devices. The most commonly used methods, such as Fault Tree Analysis (FTA), are unable to provide a reasonable basis for computing risk estimates when there are limited or no historical data available or where there is second-order uncertainty about the data. In this paper, we present a novel method for medical device risk management using hybrid Bayesian networks (BNs) that resolves the limitations of classical methods such as FTA and incorporates relevant factors affecting the risk of medical devices. The proposed BN method is generic but can be instantiated on a system-by-system basis, and we apply it to a Defibrillator device to demonstrate the process involved for medical device risk management during production and post-production. The example is validated against real-world data.

Automatic assessment of learner competencies is a fundamental task in intelligent tutoring systems. An assessment rubric typically and effectively describes relevant competencies and competence levels. This paper presents an approach to deriving a learner model directly from an assessment rubric defining some (partial) ordering of competence levels. The model is based on Bayesian networks and exploits logical gates with uncertainty (often referred to as noisy gates) to reduce the number of parameters of the model, so to simplify their elicitation by experts and allow real-time inference in intelligent tutoring systems. We illustrate how the approach can be applied to automatize the human assessment of an activity developed for testing computational thinking skills. The simple elicitation of the model starting from the assessment rubric opens up the possibility of quickly automating the assessment of several tasks, making them more easily exploitable in the context of adaptive assessment tools and intelligent tutoring systems.

Neural networks (NNs) and decision trees (DTs) are both popular models of machine learning, yet coming with mutually exclusive advantages and limitations. To bring the best of the two worlds, a variety of approaches are proposed to integrate NNs and DTs explicitly or implicitly. In this survey, these approaches are organized in a school which we term as neural trees (NTs). This survey aims to present a comprehensive review of NTs and attempts to identify how they enhance the model interpretability. We first propose a thorough taxonomy of NTs that expresses the gradual integration and co-evolution of NNs and DTs. Afterward, we analyze NTs in terms of their interpretability and performance, and suggest possible solutions to the remaining challenges. Finally, this survey concludes with a discussion about other considerations like conditional computation and promising directions towards this field. A list of papers reviewed in this survey, along with their corresponding codes, is available at: https://github.com/zju-vipa/awesome-neural-trees