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 Scientific Discovery


The Download: climate tech companies to watch and AI's discovery problem

MIT Technology Review

The Download: climate tech companies to watch and AI's discovery problem Plus: OpenAI has scrapped a new AI model over safety concerns. With the planet nearing 1.5 C of warming, climate policies being unraveled, and Big Tech backpedaling on its climate ambitions, it can be tempting to give in to climate doom and defeatism. But despite the headwinds, the world has still made incredible progress. That's why publishes its annual list of Climate Tech Companies to Watch . Once a year, we compile a list of 10 companies that we believe have done the most, or have the best chance, to make a real dent in emissions or improve public safety and health. We've now finalized our 2026 list and will publish it on October 6.


When can we say AI made a scientific discovery?

MIT Technology Review

When can we say AI made a scientific discovery? AI companies' insistence that their technology is making breakthroughs, not just aiding scientists, is making real progress harder to recognize. Last Wednesday, Anthropic announced that earlier this year it had launched a molecular biology lab, where Claude agents read and conjecture about hard biology problems and human scientists run experiments on what they report. And this AI-powered lab, the company said, had made its first discovery. To understand what Anthropic says its system did, imagine you're flipping through a library of millions of DNA sequences, amassed as scientists sequence more and more of the living world. One step toward a breakthrough might be finding a peculiar sequence that encodes an interesting enzyme, perhaps.


How NASA is prepping for lunar traffic jams

Popular Science

Gateway spaceport will make Earth's air traffic control look easy. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. The Gateway space station will be humanity's first space station around the Moon as a vital component of the Artemis missions to return humans to the lunar surface for scientific discovery and chart the path for the first human missions to Mars. Astronauts on Gateway will be the first humans to call deep space home during missions where they will use Gateway to conduct science and prepare for lunar surface missions. Breakthroughs, discoveries, and DIY tips sent six days a week.


The American revolutionaries who popularized science in the early United States

Popular Science

Benjamin Franklin and other citizen scientists are core parts of the American experiment. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Benjamin Franklin's kite experiment in 1752 was a pivotal scientific event, which demonstrated the connection between lightning and electricity. Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy .


Sample Complexity of Scientific Discovery: PAC Learnability of Compositional Function Trees

arXiv.org Machine Learning

Scientific discovery via symbolic regression is often viewed as statistically and computationally intractable because the hypothesis space of expressions grows combinatorially with depth. This paper revisits the statistical side through the lens of PAC learning, focusing on compositional function trees built from a finite vocabulary of smooth operators (e.g., $\{+,\times,\sin,\exp\}$ and affine maps). We prove that the relevant generalization quantity, Rademacher complexity, hence the excess risk, does not necessarily blow up exponentially with the number of distinct symbolic structures, but is controlled by (i) the depth $d$ and (ii) the Lipschitz constants of the base operators along the composed computation graph. Concretely, under mild Lipschitz conditions on operators and bounded affine leaves, a finite-union bound over a vocabulary of size $K=|\mathcal{H}_{\mathrm{base}}|$ together with Maurer-type vector contraction yields $\mathfrak{R}_n(\mathcal{H}_{\mathrm{comp}}^{d}) \leq (Kb\sqrt{2}L)^{d-1}\mathfrak{R}_n(\mathcal{H}_{\mathrm{comp}}^{1})$ with arity bound $b$; corresponding high-probability risk bounds scale as $\mathcal{O}(L^{d}/\sqrt{n})$ when $K,b=O(1)$ and $\mathfrak{R}_n(\mathcal{H}_{\mathrm{comp}}^{1})=O(n^{-1/2})$. We complement the theory with a modular codebase that trains differentiable operator trees (not MLPs) on synthetic "physics-like" targets of controlled depth and shows that the empirical generalization gap correlates positively with the predicted complexity term $(\widehat{L}^{d})/\sqrt{n}$.


Why are airplanes so cold? It's for your health.

Popular Science

Why are airplanes so cold? From combating fainting to helping aircraft work efficiently, planes are chilly for a reason. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. Breakthroughs, discoveries, and DIY tips sent six days a week. By signing up, you confirm you are 16+, will receive newsletters and promotional content and agree to our Terms of Use and acknowledge the data practices in our Privacy Policy .


Strategic Hypothesis Testing

Neural Information Processing Systems

We examine hypothesis testing within a principal-agent framework, where a strategic agent, holding private beliefs about the effectiveness of a product, submits data to a principal who decides on approval. The principal employs a hypothesis testing rule, aiming to pick a p-value threshold that balances false positives and false negatives while anticipating the agent's incentive to maximize expected profitability. Building on prior work, we develop a game-theoretic model that captures how the agent's participation and reporting behavior respond to the principal's statistical decision rule. Despite the complexity of the interaction, we show that the principal's errors exhibit clear monotonic behavior when segmented by an efficiently computable critical p-value threshold, leading to an interpretable characterization of their optimal p-value threshold.


Active Measurement: Efficient Estimation at Scale

Neural Information Processing Systems

AI has the potential to transform scientific discovery by analyzing vast datasets with little human effort. However, current workflows often do not provide the accuracy or statistical guarantees that are needed. We introduce active measurement, a human-in-the-loop AI framework for scientific measurement. An AI model is used to predict measurements for individual units, which are then sampled for human labeling using importance sampling. With each new set of human labels, the AI model is improved and an unbiased Monte Carlo estimate of the total measurement is refined. Active measurement can provide precise estimates even with an imperfect AI model, and requires little human effort when the AI model is very accurate. We derive novel estimators, weighting schemes, and confidence intervals, and show that active measurement reduces estimation error compared to alternatives in several measurement tasks.


Deciphering the Extremes: ANovel Approach for Pathological Long-tailed Recognition in Scientific Discovery

Neural Information Processing Systems

Scientific discovery across diverse fields increasingly grapples with datasets exhibiting pathological long-tailed distributions: a few common phenomena overshadow a multitude of rare yet scientifically critical instances. Unlike standard benchmarks, these scientific datasets often feature extreme imbalance coupled with a modest number of classes and limited overall sample volume, rendering existing long-tailed recognition (LTR) techniques ineffective. Such methods, biased by majority classes or prone to overfitting on scarce tail data, frequently fail to identify the very instances--novel materials, rare disease biomarkers, faint astronomical signals--that drive scientific breakthroughs. This paper introduces a novel, end-to-end framework explicitly designed to address pathological long-tailed recognition in scientific contexts. Our approach synergizes a Balanced Supervised Contrastive Learning (BSCL) mechanism, which enhances the representation of tail classes by dynamically re-weighting their contributions, with a Smooth Objective Regularization (SOR) strategy that manages the inherent tension between tail-class focus and overall classification performance. We introduce and analyze the real-world ZincFluor chemical dataset (T = 137.54)


AutoSciDACT: Automated Scientific Discovery through Contrastive Embedding and Hypothesis Testing

Neural Information Processing Systems

Novelty detection in large scientific datasets faces two key challenges: the noisy and high-dimensional nature of experimental data, and the necessity of making statistically robust statements about any observed outliers. While there is a wealth of literature on anomaly detection via dimensionality reduction, most methods do not produce outputs compatible with quantifiable claims of scientific discovery. In this work we directly address these challenges, presenting the first step towards a unified pipeline for novelty detection adapted for the rigorous statistical demands of science. We introduce AutoSciDACT (Automated Scientific Discovery with Anomalous Contrastive Testing), a general-purpose pipeline for detecting novelty in scientific data. AutoSciDACT begins by creating expressive low-dimensional data representations using a contrastive pre-training, leveraging the abundance of highquality simulated data in many scientific domains alongside expertise that can guide principled data augmentation strategies. These compact embeddings then enable an extremely sensitive machine learning-based two-sample test using the New Physics Learning Machine (NPLM) framework, which identifies and statistically quantifies deviations in observed data relative to a reference distribution (null hypothesis). We perform experiments across a range of astronomical, physical, biological, image, and synthetic datasets, demonstrating strong sensitivity to small injections of anomalous data across all domains.