Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro fertilization-embryo transfer (IVF-ET) procedures still encounter significant hurdles in enhancing pregnancy success rates. Key challenges include the inherent subjectivity in embryo grading and the inefficiency of multi-modal data integration. Against this backdrop, the adoption of AI-driven technologies has emerged as a pivotal strategy to address these issues. This article presents a comprehensive review of the progress in AI applications for embryo grading and pregnancy prediction from a novel perspective, with a specific focus on the utilization of different modal data, such as static images, time-lapse videos, and structured tabular data. The reason for this perspective is that reorganizing tasks based on data sources can not only more accurately depict the essence of the problem but also help clarify the rationality and limitations of model design. Furthermore, this review critically examines the core challenges in contemporary research, encompassing the intricacies of multi-modal feature fusion, constraints imposed by data scarcity, limitations in model generalization capabilities, and the dynamically evolving legal and regulatory frameworks. On this basis, it explicitly identifies potential avenues for future research, aiming to provide actionable guidance for advancing the application of multi-modal AI in the field of ART.

Gesture-based control for mobile manipulators faces persistent challenges in reliability, efficiency, and intuitiveness. This paper presents a dual-hand gesture interface that integrates TinyML, spectral analysis, and sensor fusion within a ROS framework to address these limitations. The system uses left-hand tilt and finger flexion, captured using accelerometer and flex sensors, for mobile base navigation, while right-hand IMU signals are processed through spectral analysis and classified by a lightweight neural network. This pipeline enables TinyML-based gesture recognition to control a 7-DOF Kinova Gen3 manipulator. By supporting simultaneous navigation and manipulation, the framework improves efficiency and coordination compared to sequential methods. Key contributions include a bimanual control architecture, real-time low-power gesture recognition, robust multimodal sensor fusion, and a scalable ROS-based implementation. The proposed approach advances Human-Robot Interaction (HRI) for industrial automation, assistive robotics, and hazardous environments, offering a cost-effective, open-source solution with strong potential for real-world deployment and further optimization.

In the online ride-hailing pricing context, companies often conduct randomized controlled trials (RCTs) and utilize uplift models to assess the effect of discounts on customer orders, which substantially influences competitive market outcomes. However, due to the high cost of RCTs, the proportion of trial data relative to observational data is small, which only accounts for 0.65\% of total traffic in our context, resulting in significant bias when generalizing to the broader user base. Additionally, the complexity of industrial processes reduces the quality of RCT data, which is often subject to heterogeneity from potential interference and selection bias, making it difficult to correct. Moreover, existing data fusion methods are challenging to implement effectively in complex industrial settings due to the high dimensionality of features and the strict assumptions that are hard to verify with real-world data. To address these issues, we propose an empirical data fusion method called pseudo-sample matching. By generating pseudo-samples from biased, low-quality RCT data and matching them with the most similar samples from large-scale observational data, the method expands the RCT dataset while mitigating its heterogeneity. We validated the method through simulation experiments, conducted offline and online tests using real-world data. In a week-long online experiment, we achieved a 0.41\% improvement in profit, which is a considerable gain when scaled to industrial scenarios with hundreds of millions in revenue. In addition, we discuss the harm to model training, offline evaluation, and online economic benefits when the RCT data quality is not high, and emphasize the importance of improving RCT data quality in industrial scenarios. Further details of the simulation experiments can be found in the GitHub repository https://github.com/Kairong-Han/Pseudo-Matching.

Task vectors capture how a model changes during fine-tuning by recording the difference between pre-trained and task-specific weights. The composition of task vectors, a key operator in task arithmetic, enables models to integrate knowledge from multiple tasks without incurring additional inference costs. In this paper, we propose variational task vector composition, where composition coefficients are taken as latent variables and estimated in a Bayesian inference framework. Unlike previous methods that operate at the task level, our framework focuses on sample-specific composition. Motivated by the observation of structural redundancy in task vectors, we introduce a Spike-and-Slab prior that promotes sparsity and preserves only the most informative components. To further address the high variance and sampling inefficiency in sparse, high-dimensional spaces, we develop a gated sampling mechanism that constructs a controllable posterior by filtering the composition coefficients based on both uncertainty and importance. This yields a more stable and interpretable variational framework by deterministically selecting reliable task components, reducing sampling variance while improving transparency and generalization. Experimental results demonstrate that our method consistently outperforms existing approaches across all datasets by selectively leveraging the most reliable and informative components in task vectors. These findings highlight the practical value of our approach, establishing a new standard for efficient and effective task vector composition.

Combining multimodal data is a key issue in a wide range of machine learning tasks, including many remote sensing problems. In Earth observation, early multimodal data fusion methods were based on specific neural network architectures and supervised learning. Ever since, the scarcity of labeled data has motivated self-supervised learning techniques. State-of-the-art multimodal representation learning techniques leverage the spatial alignment between satellite data from different modalities acquired over the same geographic area in order to foster a semantic alignment in the latent space. In this paper, we investigate how this methods can preserve task-relevant information that is not shared across modalities. First, we show, under simplifying assumptions, when alignment strategies fundamentally lead to an information loss. Then, we support our theoretical insight through numerical experiments in more realistic settings. With those theoretical and empirical evidences, we hope to support new developments in contrastive learning for the combination of multimodal satellite data. Our code and data is publicly available at https://github.com/Romain3Ch216/alg_maclean_25.

The debate around Artificial General Intelligence (AGI) remains open due to two fundamentally different goals: replicating human-like performance versus replicating human-like cognitive processes. We argue that current performance-based definitions are inadequate because they provide no clear, mechanism-focused roadmap for research, and they fail to properly define the qualitative nature of genuine intelligence. Drawing inspiration from the human brain, we propose a new paradigm that shifts the focus from external mimicry to the development of foundational cognitive architectures. We define True Intelligence (TI) as a system characterized by six core components: embodied sensory fusion, core directives, dynamic schemata creation, a highly-interconnected multi-expert architecture, an orchestration layer, and lastly, the unmeasurable quality of Interconnectedness, which we hypothesize results in consciousness and a subjective experience. We propose a practical, five-level taxonomy of AGI based on the number of the first five measurable components a system exhibits. This framework provides a clear path forward with developmental milestones that directly address the challenge of building genuinely intelligent systems. We contend that once a system achieves Level-5 AGI by implementing all five measurable components, the difference between it and TI remains as a purely philosophical debate. For practical purposes - and given theories indicate consciousness is an emergent byproduct of integrated, higher-order cognition - we conclude that a fifth-level AGI is functionally and practically equivalent to TI. This work synthesizes diverse insights from analytical psychology, schema theory, metacognition, modern brain architectures and latest works in AI to provide the first holistic, mechanism-based definition of AGI that offers a clear and actionable path for the research community.

Reliable, drift-free global localization presents significant challenges yet remains crucial for autonomous navigation in large-scale dynamic environments. In this paper, we introduce a tightly-coupled Semantic-LiDAR-Inertial-Wheel Odometry fusion framework, which is specifically designed to provide high-precision state estimation and robust localization in large-scale dynamic environments. Our framework leverages an efficient semantic-voxel map representation and employs an improved scan matching algorithm, which utilizes global semantic information to significantly reduce long-term trajectory drift. Furthermore, it seamlessly fuses data from LiDAR, IMU, and wheel odometry using a tightly-coupled multi-sensor fusion Iterative Error-State Kalman Filter (iESKF). This ensures reliable localization without experiencing abnormal drift. Moreover, to tackle the challenges posed by terrain variations and dynamic movements, we introduce a 3D adaptive scaling strategy that allows for flexible adjustments to wheel odometry measurement weights, thereby enhancing localization precision. This study presents extensive real-world experiments conducted in a one-million-square-meter automated port, encompassing 3,575 hours of operational data from 35 Intelligent Guided Vehicles (IGVs). The results consistently demonstrate that our system outperforms state-of-the-art LiDAR-based localization methods in large-scale dynamic environments, highlighting the framework's reliability and practical value.

This paper introduces the concept of a mean for trajectories and multi-object trajectories (defined as sets or multi-sets of trajectories) along with algorithms for computing them. Specifically, we use the Fréchet mean, and metrics based on the optimal sub-pattern assignment (OSPA) construct, to extend the notion of average from vectors to trajectories and multi-object trajectories. Further, we develop efficient algorithms to compute these means using greedy search and Gibbs sampling. Using distributed multi-object tracking as an application, we demonstrate that the Fréchet mean approach to multi-object trajectory consensus significantly outperforms state-of-the-art distributed multi-object tracking methods.

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly generalizable representations. Here we present MICE (Multimodal data Integration via Collaborative Experts), a multimodal foundation model that effectively integrates pathology images, clinical reports, and genomics data for precise pan-cancer prognosis prediction. Instead of conventional multi-expert modules, MICE employs multiple functionally diverse experts to comprehensively capture both cross-cancer and cancer-specific insights. Leveraging data from 11,799 patients across 30 cancer types, we enhanced MICE's generalizability by coupling contrastive and supervised learning. MICE outperformed both unimodal and state-of-the-art multi-expert-based multimodal models, demonstrating substantial improvements in C-index ranging from 3.8% to 11.2% on internal cohorts and 5.8% to 8.8% on independent cohorts, respectively. Moreover, it exhibited remarkable data efficiency across diverse clinical scenarios. With its enhanced generalizability and data efficiency, MICE establishes an effective and scalable foundation for pan-cancer prognosis prediction, holding strong potential to personalize tailored therapies and improve treatment outcomes.