Diagnosis
Natural Language Processing for Cardiology: A Narrative Review
Yang, Kailai, Leng, Yan, Zhang, Xin, Zhang, Tianlin, Thompson, Paul, Keavney, Bernard, Tomaszewski, Maciej, Ananiadou, Sophia
Cardiovascular diseases are becoming increasingly prevalent in modern society, with a profound impact on global health and well-being. These Cardiovascular disorders are complex and multifactorial, influenced by genetic predispositions, lifestyle choices, and diverse socioeconomic and clinical factors. Information about these interrelated factors is dispersed across multiple types of textual data, including patient narratives, medical records, and scientific literature. Natural language processing (NLP) has emerged as a powerful approach for analysing such unstructured data, enabling healthcare professionals and researchers to gain deeper insights that may transform the diagnosis, treatment, and prevention of cardiac disorders. This review provides a comprehensive overview of NLP research in cardiology from 2014 to 2025. We systematically searched six literature databases for studies describing NLP applications across a range of cardiovascular diseases. After a rigorous screening process, we identified 265 relevant articles. Each study was analysed across multiple dimensions, including NLP paradigms, cardiology-related tasks, disease types, and data sources. Our findings reveal substantial diversity within these dimensions, reflecting the breadth and evolution of NLP research in cardiology. A temporal analysis further highlights methodological trends, showing a progression from rule-based systems to large language models. Finally, we discuss key challenges and future directions, such as developing interpretable LLMs and integrating multimodal data. To the best of our knowledge, this review represents the most comprehensive synthesis of NLP research in cardiology to date.
Benchmarking noisy label detection methods
Pickler, Henrique, Kamassury, Jorge K. S., Silva, Danilo
Label noise is a common problem in real-world datasets, affecting both model training and validation. Clean data are essential for achieving strong performance and ensuring reliable evaluation. While various techniques have been proposed to detect noisy labels, there is no clear consensus on optimal approaches. We perform a comprehensive benchmark of detection methods by decomposing them into three fundamental components: label agreement function, aggregation method, and information gathering approach (in-sample vs out-of-sample). This decomposition can be applied to many existing detection methods, and enables systematic comparison across diverse approaches. To fairly compare methods, we propose a unified benchmark task, detecting a fraction of training samples equal to the dataset's noise rate. We also introduce a novel metric: the false negative rate at this fixed operating point. We identify that in-sample information gathering using average probability aggregation combined with the logit margin as the label agreement function achieves the best results across most scenarios. Our findings provide practical guidance for designing new detection methods and selecting techniques for specific applications. Keywords: Noisy label detection, Noisy labels, Dataset cleaning, Data quality, Benchmark, Neural networks 1. Introduction Most supervised learning methods assume a perfectly labeled dataset. However, training data often contain incorrectly labeled instances. Even large, standard benchmark datasets, such as CIFAR, ImageNet, and MS-COCO, are known to have noisy labels [1, 2].
A Scoping Review of Machine Learning Applications in Power System Protection and Disturbance Management
Oelhaf, Julian, Kordowich, Georg, Pashaei, Mehran, Bergler, Christian, Maier, Andreas, Jรคger, Johann, Bayer, Siming
The integration of renewable and distributed energy resources reshapes modern power systems, challenging conventional protection schemes. This scoping review synthesizes recent literature on machine learning (ML) applications in power system protection and disturbance management, following the PRISMA for Scoping Reviews framework. Based on over 100 publications, three key objectives are addressed: (i) assessing the scope of ML research in protection tasks; (ii) evaluating ML performance across diverse operational scenarios; and (iii) identifying methods suitable for evolving grid conditions. ML models often demonstrate high accuracy on simulated datasets; however, their performance under real-world conditions remains insufficiently validated. The existing literature is fragmented, with inconsistencies in methodological rigor, dataset quality, and evaluation metrics. This lack of standardization hampers the comparability of results and limits the generalizability of findings. To address these challenges, this review introduces a ML-oriented taxonomy for protection tasks, resolves key terminological inconsistencies, and advocates for standardized reporting practices. It further provides guidelines for comprehensive dataset documentation, methodological transparency, and consistent evaluation protocols, aiming to improve reproducibility and enhance the practical relevance of research outcomes. Critical gaps remain, including the scarcity of real-world validation, insufficient robustness testing, and limited consideration of deployment feasibility. Future research should prioritize public benchmark datasets, realistic validation methods, and advanced ML architectures. These steps are essential to move ML-based protection from theoretical promise to practical deployment in increasingly dynamic and decentralized power systems.
PhysioWave: A Multi-Scale Wavelet-Transformer for Physiological Signal Representation
Chen, Yanlong, Orlandi, Mattia, Rapa, Pierangelo Maria, Benatti, Simone, Benini, Luca, Li, Yawei
Physiological signals are often corrupted by motion artifacts, baseline drift, and other low-SNR disturbances, which pose significant challenges for analysis. Additionally, these signals exhibit strong non-stationarity, with sharp peaks and abrupt changes that evolve continuously, making them difficult to represent using traditional time-domain or filtering methods. To address these issues, a novel wavelet-based approach for physiological signal analysis is presented, aiming to capture multi-scale time-frequency features in various physiological signals. Leveraging this technique, two large-scale pretrained models specific to EMG and ECG are introduced for the first time, achieving superior performance and setting new baselines in downstream tasks. Additionally, a unified multi-modal framework is constructed by integrating pretrained EEG model, where each modality is guided through its dedicated branch and fused via learnable weighted fusion. This design effectively addresses challenges such as low signal-to-noise ratio, high inter-subject variability, and device mismatch, outperforming existing methods on multi-modal tasks. The proposed wavelet-based architecture lays a solid foundation for analysis of diverse physiological signals, while the multi-modal design points to next-generation physiological signal processing with potential impact on wearable health monitoring, clinical diagnostics, and broader biomedical applications. Code and data are available at: github.com/ForeverBlue816/PhysioWave
Foundation Models in Medical Image Analysis: A Systematic Review and Meta-Analysis
Rajendran, Praveenbalaji, Safari, Mojtaba, He, Wenfeng, Hu, Mingzhe, Wang, Shansong, Zhou, Jun, Yang, Xiaofeng
Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from segmentation to report generation. Unlike traditional task-specific AI models, FMs leverage large corpora of labeled and unlabeled multimodal datasets to learn generalized representations that can be adapted to various downstream clinical applications with minimal fine-tuning. However, despite the rapid proliferation of FM research in medical imaging, the field remains fragmented, lacking a unified synthesis that systematically maps the evolution of architectures, training paradigms, and clinical applications across modalities. To address this gap, this review article provides a comprehensive and structured analysis of FMs in medical image analysis. We systematically categorize studies into vision-only and vision-language FMs based on their architectural foundations, training strategies, and downstream clinical tasks. Additionally, a quantitative meta-analysis of the studies was conducted to characterize temporal trends in dataset utilization and application domains. We also critically discuss persistent challenges, including domain adaptation, efficient fine-tuning, computational constraints, and interpretability along with emerging solutions such as federated learning, knowledge distillation, and advanced prompting. Finally, we identify key future research directions aimed at enhancing the robustness, explainability, and clinical integration of FMs, thereby accelerating their translation into real-world medical practice.
SNOMED CT-powered Knowledge Graphs for Structured Clinical Data and Diagnostic Reasoning
Liu, Dun, Pang, Qin, Liu, Guangai, Mou, Hongyu, Fan, Jipeng, Miao, Yiming, Ho, Pin-Han, Peng, Limei
The effectiveness of artificial intelligence (AI) in healthcare is significantly hindered by unstructured clinical documentation, which results in noisy, inconsistent, and logically fragmented training data. To address this challenge, we present a knowledge-driven framework that integrates the standardized clinical terminology SNOMED CT with the Neo4j graph database to construct a structured medical knowledge graph. In this graph, clinical entities such as diseases, symptoms, and medications are represented as nodes, and semantic relationships such as ``caused by,'' ``treats,'' and ``belongs to'' are modeled as edges in Neo4j, with types mapped from formal SNOMED CT relationship concepts (e.g., \texttt{Causative agent}, \texttt{Indicated for}). This design enables multi-hop reasoning and ensures terminological consistency. By extracting and standardizing entity-relationship pairs from clinical texts, we generate structured, JSON-formatted datasets that embed explicit diagnostic pathways. These datasets are used to fine-tune large language models (LLMs), significantly improving the clinical logic consistency of their outputs. Experimental results demonstrate that our knowledge-guided approach enhances the validity and interpretability of AI-generated diagnostic reasoning, providing a scalable solution for building reliable AI-assisted clinical systems.
Effect of Reporting Mode and Clinical Experience on Radiologists' Gaze and Image Analysis Behavior in Chest Radiography
Khoobi, Mahta, von der Stueck, Marc Sebastian, Ordonez, Felix Barajas, Iancu, Anca-Maria, Corban, Eric, Nowak, Julia, Kargaliev, Aleksandar, Perelygina, Valeria, Schott, Anna-Sophie, Santos, Daniel Pinto dos, Kuhl, Christiane, Truhn, Daniel, Nebelung, Sven, Siepmann, Robert
Structured reporting (SR) and artificial intelligence (AI) may transform how radiologists interact with imaging studies. This prospective study (July to December 2024) evaluated the impact of three reporting modes: free-text (FT), structured reporting (SR), and AI-assisted structured reporting (AI-SR), on image analysis behavior, diagnostic accuracy, efficiency, and user experience. Four novice and four non-novice readers (radiologists and medical students) each analyzed 35 bedside chest radiographs per session using a customized viewer and an eye-tracking system. Outcomes included diagnostic accuracy (compared with expert consensus using Cohen's $ฮบ$), reporting time per radiograph, eye-tracking metrics, and questionnaire-based user experience. Statistical analysis used generalized linear mixed models with Bonferroni post-hoc tests with a significance level of ($P \le .01$). Diagnostic accuracy was similar in FT ($ฮบ= 0.58$) and SR ($ฮบ= 0.60$) but higher in AI-SR ($ฮบ= 0.71$, $P < .001$). Reporting times decreased from $88 \pm 38$ s (FT) to $37 \pm 18$ s (SR) and $25 \pm 9$ s (AI-SR) ($P < .001$). Saccade counts for the radiograph field ($205 \pm 135$ (FT), $123 \pm 88$ (SR), $97 \pm 58$ (AI-SR)) and total fixation duration for the report field ($11 \pm 5$ s (FT), $5 \pm 3$ s (SR), $4 \pm 1$ s (AI-SR)) were lower with SR and AI-SR ($P < .001$ each). Novice readers shifted gaze towards the radiograph in SR, while non-novice readers maintained their focus on the radiograph. AI-SR was the preferred mode. In conclusion, SR improves efficiency by guiding visual attention toward the image, and AI-prefilled SR further enhances diagnostic accuracy and user satisfaction.
Global-focal Adaptation with Information Separation for Noise-robust Transfer Fault Diagnosis
Ren, Junyu, Gan, Wensheng, Zhang, Guangyu, Zhong, Wei, Yu, Philip S.
Rotating machinery [1] is critical in industrial applications, where system reliability is essential to avoid financial losses and safety risks. Therefore, timely fault diagnosis is a crucial engineering priority. Deep learning-based fault diagnosis has achieved remarkable success due to its ability to extract features and model complex nonlinear relationships [2, 3]. However, industrial rotating machines operate under diverse conditions, leading to domain shifts that degrade the diagnostic performance of conventional deep learning methods [4]. Among the powerful artificial intelligence (AI) technologies, transfer learning [5] can address these limitations through cross-task knowledge transfer, where domain adaptation has become a widely adopted technique in fault diagnosis, primarily encompassing metric-based approaches, adversarial frameworks, and their hybrid variants [4, 6]. Currently, cross-domain fault diagnosis methods have been extended to encompass a wider range of diverse and practical application scenarios [7]. Given that source domain data are often more abundant in real-world settings, several studies have proposed multi-source transfer fault diagnosis approaches [8, 9]. For closed-set scenarios, various domain adaptation methods have been developed [10]. Since the label categories between source and target domains may not be completely identical, open-set domain adaptation and partial domain adaptation methods have been developed for fault diagnosis [11].
Hypergraph Contrastive Sensor Fusion for Multimodal Fault Diagnosis in Induction Motors
Ali, Usman, Zia, Ali, Ali, Waqas, Ramzan, Umer, Rehman, Abdul, Chaudhry, Muhammad Tayyab, Xiang, Wei
Abstract--Reliable induction motor (IM) fault diagnosis is vital for industrial safety and operational continuity, mitigating costly unplanned downtime. Conventional approaches often struggle to capture complex multimodal signal relationships, are constrained to unimodal data or single fault types, and exhibit performance degradation under noisy or cross-domain conditions. This paper proposes the Multimodal Hypergraph Contrastive Attention Network (MM-HCAN), a unified framework for robust fault diagnosis. T o the best of our knowledge, MM-HCAN is the first to integrate contrastive learning within a hypergraph topology specifically designed for multimodal sensor fusion, enabling the joint modelling of intra-and inter-modal dependencies and enhancing generalisation beyond Euclidean embedding spaces. Evaluated on three real-world benchmarks, MM-HCAN achieves up to 99.82% accuracy with strong cross-domain generalisation and resilience to noise, demonstrating its suitability for real-world deployment. MM-HCAN provides a scalable and robust solution for comprehensive multi-fault diagnosis, supporting predictive maintenance and extended asset longevity in industrial environments. NDUCTION motors (IMs) are essential to modern industrial systems, supporting sectors like manufacturing, energy, and transportation. However, faults in IMs can cause downtime, high maintenance costs, and substantial economic losses. As a result, fault diagnosis in IMs has become a focal point of research, with recent studies highlighting its importance in enhancing operational resilience and minimising financial impacts. IMs faults are broadly classified as either electrical, with stator faults comprising 28-36%, or mechanical, encompassing bearing (42-55%) and rotor (8-10%) failures [1].
Where are the Whales: A Human-in-the-loop Detection Method for Identifying Whales in High-resolution Satellite Imagery
Robinson, Caleb, Goetz, Kimberly T., Khan, Christin B., Sackett, Meredith, Leonard, Kathleen, Dodhia, Rahul, Ferres, Juan M. Lavista
Effective monitoring of whale populations is critical for conservation, but traditional survey methods are expensive and difficult to scale. While prior work has shown that whales can be identified in very high-resolution (VHR) satellite imagery, large-scale automated detection remains challenging due to a lack of annotated imagery, variability in image quality and environmental conditions, and the cost of building robust machine learning pipelines over massive remote sensing archives. We present a semi-automated approach for surfacing possible whale detections in VHR imagery using a statistical anomaly detection method that flags spatial outliers, i.e. "interesting points". We pair this detector with a web-based labeling interface designed to enable experts to quickly annotate the interesting points. We evaluate our system on three benchmark scenes with known whale annotations and achieve recalls of 90.3% to 96.4%, while reducing the area requiring expert inspection by up to 99.8% -- from over 1,000 sq km to less than 2 sq km in some cases. Our method does not rely on labeled training data and offers a scalable first step toward future machine-assisted marine mammal monitoring from space. We have open sourced this pipeline at https://github.com/microsoft/whales.