Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce confounding heterogeneity due to multiple disease subtypes being labeled under a single category. To address these challenges, we propose a novel federated learning framework tailored for neuroimaging CAD systems. Our approach includes a dynamic navigation module that routes samples to the most suitable local models based on latent subtype representations, and a meta-integration module that combines predictions from heterogeneous local models into a unified diagnostic output. We evaluated our framework using a comprehensive dataset comprising fMRI data from over 1300 MDD patients and 1100 healthy controls across multiple study cohorts. Experimental results demonstrate significant improvements in diagnostic accuracy and robustness compared to traditional methods. Specifically, our framework achieved an average accuracy of 74.06\% across all tested sites, showcasing its effectiveness in handling subtype heterogeneity and enhancing model generalizability. Ablation studies further confirmed the importance of both the dynamic navigation and meta-integration modules in improving performance. By addressing data heterogeneity and subtype confounding, our framework advances reliable and reproducible neuroimaging CAD systems, offering significant potential for personalized medicine and clinical decision-making in neurology and psychiatry.

In oral cancer diagnostics, the limited availability of annotated datasets frequently constrains the performance of diagnostic models, particularly due to the variability and insufficiency of training data. To address these challenges, this study proposed a novel approach to enhance diagnostic accuracy by synthesizing realistic oral cancer lesions using an inpainting technique with a fine-tuned diffusion model. We compiled a comprehensive dataset from multiple sources, featuring a variety of oral cancer images. Our method generated synthetic lesions that exhibit a high degree of visual fidelity to actual lesions, thereby significantly enhancing the performance of diagnostic algorithms. The results show that our classification model achieved a diagnostic accuracy of 0.97 in differentiating between cancerous and non-cancerous tissues, while our detection model accurately identified lesion locations with 0.85 accuracy. This method validates the potential for synthetic image generation in medical diagnostics and paves the way for further research into extending these methods to other types of cancer diagnostics.

This work contributes to a real-time data-driven predictive maintenance solution for Intelligent Transportation Systems. The proposed method implements a processing pipeline comprised of sample pre-processing, incremental classification with Machine Learning models, and outcome explanation. This novel online processing pipeline has two main highlights: (i) a dedicated sample pre-processing module, which builds statistical and frequency-related features on the fly, and (ii) an explainability module. This work is the first to perform online fault prediction with natural language and visual explainability. The experiments were performed with the MetroPT data set from the metro operator of Porto, Portugal. The results are above 98 % for F-measure and 99 % for accuracy. In the context of railway predictive maintenance, achieving these high values is crucial due to the practical and operational implications of accurate failure prediction. In the specific case of a high F-measure, this ensures that the system maintains an optimal balance between detecting the highest possible number of real faults and minimizing false alarms, which is crucial for maximizing service availability. Furthermore, the accuracy obtained enables reliability, directly impacting cost reduction and increased safety. The analysis demonstrates that the pipeline maintains high performance even in the presence of class imbalance and noise, and its explanations effectively reflect the decision-making process. These findings validate the methodological soundness of the approach and confirm its practical applicability for supporting proactive maintenance decisions in real-world railway operations. Therefore, by identifying the early signs of failure, this pipeline enables decision-makers to understand the underlying problems and act accordingly swiftly.

This paper proposes a novel graph-based framework for robust and interpretable multiclass fault diagnosis in rotating machinery. The method integrates entropy-optimized signal segmentation, time-frequency feature extraction, and graph-theoretic modeling to transform vibration signals into structured representations suitable for classification. Graph metrics, such as average shortest path length, modularity, and spectral gap, are computed and combined with local features to capture global and segment-level fault characteristics. The proposed method achieves high diagnostic accuracy when evaluated on two benchmark datasets, the CWRU bearing dataset (under 0-3 HP loads) and the SU gearbox and bearing datasets (under different speed-load configurations). Classification scores reach up to 99.8% accuracy on Case Western Reserve University (CWRU) and 100% accuracy on the Southeast University datasets using a logistic regression classifier. Furthermore, the model exhibits strong noise resilience, maintaining over 95.4% accuracy at high noise levels (standard deviation = 0.5), and demonstrates excellent cross-domain transferability with up to 99.7% F1-score in load-transfer scenarios. Compared to traditional techniques, this approach requires no deep learning architecture, enabling lower complexity while ensuring interpretability. The results confirm the method's scalability, reliability, and potential for real-time deployment in industrial diagnostics.

Physicians routinely assess respiratory sounds during the diagnostic process, providing insight into the condition of a patient's airways. In recent years, AI-based diagnostic systems operating on respiratory sounds, have demonstrated success in respiratory disease detection. These systems represent a crucial advancement in early and accessible diagnosis which is essential for timely treatment. However, label and data scarcity remain key challenges, especially for conditions beyond COVID-19, limiting diagnostic performance and reliable evaluation. In this paper, we propose CoughViT, a novel pre-training framework for learning general-purpose cough sound representations, to enhance diagnostic performance in tasks with limited data. To address label scarcity, we employ masked data modelling to train a feature encoder in a self-supervised learning manner. We evaluate our approach against other pre-training strategies on three diagnostically important cough classification tasks. Experimental results show that our representations match or exceed current state-of-the-art supervised audio representations in enhancing performance on downstream tasks.

In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the challenge hinder the practical deployment of RAG for medical diagnosis: the semantic gap between colloquial patient descriptions and the professional terminology within medical knowledge bases. We try to address the challenge from the data perspective and the method perspective. First, to address the semantic gap in existing knowledge bases, we construct DiagnosGraph, a generalist knowledge graph covering both modern medicine and Traditional Chinese Medicine. It contains 876 common diseases with the graph of 7,997 nodes and 37,201 triples. To bridge the gap between colloquial patient narratives and academic medical knowledge, DiagnosGraph also introduces $1,908$ medical record by formalizing the patient chief complaint and proposing a medical diagnosis. Second, we introduce the Multi-Round Diagnostic RAG (MRD-RAG) framework. It utilizes a multi-round dialogue to refine diagnostic possibilities, emulating the clinical reasoning of a physician. Experiments conducted on four medical benchmarks, with evaluations by human physicians, demonstrate that MRD-RAG enhances the diagnostic performance of LLMs, highlighting its potential to make automated diagnosis more accurate and human-aligned.

Fault detection is crucial for ensuring the safety and reliability of modern industrial systems. However, a significant scientific challenge is the lack of rigorous risk control and reliable uncertainty quantification in existing diagnostic models, particularly when facing complex scenarios such as distributional shifts. To address this issue, this paper proposes a novel fault detection method that integrates significance testing with the conformal prediction framework to provide formal risk guarantees. The method transforms fault detection into a hypothesis testing task by defining a nonconformity measure based on model residuals. It then leverages a calibration dataset to compute p-values for new samples, which are used to construct prediction sets mathematically guaranteed to contain the true label with a user-specified probability, $1-α$. Fault classification is subsequently performed by analyzing the intersection of the constructed prediction set with predefined normal and fault label sets. Experimental results on cross-domain fault diagnosis tasks validate the theoretical properties of our approach. The proposed method consistently achieves an empirical coverage rate at or above the nominal level ($1-α$), demonstrating robustness even when the underlying point-prediction models perform poorly. Furthermore, the results reveal a controllable trade-off between the user-defined risk level ($α$) and efficiency, where higher risk tolerance leads to smaller average prediction set sizes. This research contributes a theoretically grounded framework for fault detection that enables explicit risk control, enhancing the trustworthiness of diagnostic systems in safety-critical applications and advancing the field from simple point predictions to informative, uncertainty-aware outputs.

Reproducibility is a cornerstone of scientific research, enabling independent verification and validation of empirical findings. The topic gained prominence in fields such as psychology and medicine, where concerns about non - replicable results sparked ongoing discussions about research practices. In recent years, the fast-growing field of Machine Learning (ML) has become part of this discourse, as it faces similar concerns about transparency and reliability. Some reproducibility issues in ML research are shared with other fields, such as limited access to data and missing methodological details. In addition, ML introduces specific challenges, including inherent nondeterminism and computational constraints. While reproducibility issues are increasingly recognized by the ML community and its major conferences, less is known about how these challenges manifest in applied disciplines. This paper contributes to closing this gap by analyzing the transparency and reproducibility standards of ML applications in building energy systems. The results indicate that nearly all articles are not reproducible due to insufficient disclosure across key dimensions of reproducibility. 72% of the articles do not specify whether the dataset used is public, proprietary, or commercially available. Only two papers share a link to their code - one of which was broken. Two-thirds of the publications were authored exclusively by academic researchers, yet no significant differences in reproducibility were observed compared to publications with industry-affiliated authors. These findings highlight the need for targeted interventions, including reproducibility guidelines, training for researchers, and policies by journals and conferences that promote transparency and reproducibility.

The diagnosis of induction machines has traditionally relied on model-based methods that require the development of complex dynamic models, making them difficult to implement and computationally expensive. To overcome these limitations, this paper proposes a model-free approach using Graph Neural Networks (GNNs) for fault diagnosis in induction machines. The focus is on detecting multiple fault types -- including eccentricity, bearing defects, and broken rotor bars -- under varying severity levels and load conditions. Unlike traditional approaches, raw current and vibration signals are used as direct inputs, eliminating the need for signal preprocessing or manual feature extraction. The proposed GNN-ASE model automatically learns and extracts relevant features from raw inputs, leveraging the graph structure to capture complex relationships between signal types and fault patterns. It is evaluated for both individual fault detection and multi-class classification of combined fault conditions. Experimental results demonstrate the effectiveness of the proposed model, achieving 92.5\% accuracy for eccentricity defects, 91.2\% for bearing faults, and 93.1\% for broken rotor bar detection. These findings highlight the model's robustness and generalization capability across different operational scenarios. The proposed GNN-based framework offers a lightweight yet powerful solution that simplifies implementation while maintaining high diagnostic performance. It stands as a promising alternative to conventional model-based diagnostic techniques for real-world induction machine monitoring and predictive maintenance.

Objective: This review aims to explore the potential and challenges of using Natural Language Processing (NLP) to detect, correct, and mitigate medically inaccurate information, including errors, misinformation, and hallucination. By unifying these concepts, the review emphasizes their shared methodological foundations and their distinct implications for healthcare. Our goal is to advance patient safety, improve public health communication, and support the development of more reliable and transparent NLP applications in healthcare. Methods: A scoping review was conducted following PRISMA guidelines, analyzing studies from 2020 to 2024 across five databases. Studies were selected based on their use of NLP to address medically inaccurate information and were categorized by topic, tasks, document types, datasets, models, and evaluation metrics. Results: NLP has shown potential in addressing medically inaccurate information on the following tasks: (1) error detection (2) error correction (3) misinformation detection (4) misinformation correction (5) hallucination detection (6) hallucination mitigation. However, challenges remain with data privacy, context dependency, and evaluation standards. Conclusion: This review highlights the advancements in applying NLP to tackle medically inaccurate information while underscoring the need to address persistent challenges. Future efforts should focus on developing real-world datasets, refining contextual methods, and improving hallucination management to ensure reliable and transparent healthcare applications.