This paper studies a stochastic dynamic game between two competing teams, each consisting of a network of collaborating agents. Unlike fully cooperative settings, where all agents share a common objective, each team in this game aims to minimize its own distinct objective. In the adversarial setting, their objectives could be conflicting as in zero-sum games. Throughout the competition, agents share strategic information within their own team while simultaneously inferring and adapting to the strategies of the opposing team. We propose diffusion learning algorithms to address two important classes of this network game: i) a zero-sum game characterized by weak cross-team subgraph interactions, and ii) a general non-zero-sum game exhibiting strong cross-team subgraph interactions. We analyze the stability performance of the proposed algorithms under reasonable assumptions and illustrate the theoretical results through experiments on Cournot team competition and decentralized GAN training.

In the trajectory planning of automated driving, data-driven statistical artificial intelligence (AI) methods are increasingly established for predicting the emergent behavior of other road users. While these methods achieve exceptional performance in defined datasets, they usually rely on the independent and identically distributed (i.i.d.) assumption and thus tend to be vulnerable to distribution shifts that occur in the real world. In addition, these methods lack explainability due to their black box nature, which poses further challenges in terms of the approval process and social trustworthiness. Therefore, in order to use the capabilities of data-driven statistical AI methods in a reliable and trustworthy manner, the concept of TrustMHE is introduced and investigated in this paper. TrustMHE represents a complementary approach, independent of the underlying AI systems, that combines AI-driven out-of-distribution detection with control-driven moving horizon estimation (MHE) to enable not only detection and monitoring, but also intervention. The effectiveness of the proposed TrustMHE is evaluated and proven in three simulation scenarios.

In recent years, multi-agent frameworks powered by large language models (LLMs) have advanced rapidly. Despite this progress, there is still a notable absence of benchmark datasets specifically tailored to evaluate their performance. To bridge this gap, we introduce Auto-SLURP, a benchmark dataset aimed at evaluating LLM-based multi-agent frameworks in the context of intelligent personal assistants. Auto-SLURP extends the original SLURP dataset -- initially developed for natural language understanding tasks -- by relabeling the data and integrating simulated servers and external services. This enhancement enables a comprehensive end-to-end evaluation pipeline, covering language understanding, task execution, and response generation. Our experiments demonstrate that Auto-SLURP presents a significant challenge for current state-of-the-art frameworks, highlighting that truly reliable and intelligent multi-agent personal assistants remain a work in progress. The dataset and related code are available at https://github.com/lorashen/Auto-SLURP/.

Using multiple agents was found to improve the debugging capabilities of Large Language Models. However, increasing the number of LLM-agents has several drawbacks such as increasing the running costs and rising the risk for the agents to lose focus. In this work, we propose an adaptive agentic design, where the number of agents and their roles are determined dynamically based on the characteristics of the task to be achieved. In this design, the agents roles are not predefined, but are generated after analyzing the problem to be solved. Our initial evaluation shows that, with the adaptive design, the number of agents that are generated depends on the complexity of the buggy code. In fact, for simple code with mere syntax issues, the problem was usually fixed using one agent only. However, for more complex problems, we noticed the creation of a higher number of agents. Regarding the effectiveness of the fix, we noticed an average improvement of 11% compared to the one-shot prompting. Given these promising results, we outline future research directions to improve our design for adaptive software agents that can autonomously plan and conduct their software goals.

Automating structured clinical interviews could revolutionize mental healthcare accessibility, yet existing large language models (LLMs) approaches fail to align with psychiatric diagnostic protocols. We present MAGI, the first framework that transforms the gold-standard Mini International Neuropsychiatric Interview (MINI) into automatic computational workflows through coordinated multi-agent collaboration. MAGI dynamically navigates clinical logic via four specialized agents: 1) an interview tree guided navigation agent adhering to the MINI's branching structure, 2) an adaptive question agent blending diagnostic probing, explaining, and empathy, 3) a judgment agent validating whether the response from participants meet the node, and 4) a diagnosis Agent generating Psychometric Chain-of- Thought (PsyCoT) traces that explicitly map symptoms to clinical criteria. Experimental results on 1,002 real-world participants covering depression, generalized anxiety, social anxiety and suicide shows that MAGI advances LLM- assisted mental health assessment by combining clinical rigor, conversational adaptability, and explainable reasoning.

Drug discovery remains a formidable challenge: more than 90 percent of candidate molecules fail in clinical evaluation, and development costs often exceed one billion dollars per approved therapy. Disparate data streams, from genomics and transcriptomics to chemical libraries and clinical records, hinder coherent mechanistic insight and slow progress. Meanwhile, large language models excel at reasoning and tool integration but lack the modular specialization and iterative memory required for regulated, hypothesis-driven workflows. We introduce PharmaSwarm, a unified multi-agent framework that orchestrates specialized LLM "agents" to propose, validate, and refine hypotheses for novel drug targets and lead compounds. Each agent accesses dedicated functionality--automated genomic and expression analysis; a curated biomedical knowledge graph; pathway enrichment and network simulation; interpretable binding affinity prediction--while a central Evaluator LLM continuously ranks proposals by biological plausibility, novelty, in silico efficacy, and safety. A shared memory layer captures validated insights and fine-tunes underlying submodels over time, yielding a self-improving system. Deployable on low-code platforms or Kubernetes-based microservices, PharmaSwarm supports literature-driven discovery, omics-guided target identification, and market-informed repurposing. We also describe a rigorous four-tier validation pipeline spanning retrospective benchmarking, independent computational assays, experimental testing, and expert user studies to ensure transparency, reproducibility, and real-world impact. By acting as an AI copilot, PharmaSwarm can accelerate translational research and deliver high-confidence hypotheses more efficiently than traditional pipelines.

Collaboration is ubiquitous and essential in day-to-day life -- from exchanging ideas, to delegating tasks, to generating plans together. This work studies how LLMs can adaptively collaborate to perform complex embodied reasoning tasks. To this end we introduce MINDcraft, an easily extensible platform built to enable LLM agents to control characters in the open-world game of Minecraft; and MineCollab, a benchmark to test the different dimensions of embodied and collaborative reasoning. An experimental study finds that the primary bottleneck in collaborating effectively for current state-of-the-art agents is efficient natural language communication, with agent performance dropping as much as 15% when they are required to communicate detailed task completion plans. We conclude that existing LLM agents are ill-optimized for multi-agent collaboration, especially in embodied scenarios, and highlight the need to employ methods beyond in-context and imitation learning. Our website can be found here: https://mindcraft-minecollab.github.io/

Recent Computer-Using Agents (CUAs), powered by multimodal large language models (LLMs), offer a promising direction for automating complex desktop workflows through natural language. However, most existing CUAs remain conceptual prototypes, hindered by shallow OS integration, fragile screenshot-based interaction, and disruptive execution. We present UFO2, a multiagent AgentOS for Windows desktops that elevates CUAs into practical, system-level automation. UFO2 features a centralized HostAgent for task decomposition and coordination, alongside a collection of application-specialized AppAgent equipped with native APIs, domain-specific knowledge, and a unified GUI--API action layer. This architecture enables robust task execution while preserving modularity and extensibility. A hybrid control detection pipeline fuses Windows UI Automation (UIA) with vision-based parsing to support diverse interface styles. Runtime efficiency is further enhanced through speculative multi-action planning, reducing per-step LLM overhead. Finally, a Picture-in-Picture (PiP) interface enables automation within an isolated virtual desktop, allowing agents and users to operate concurrently without interference. We evaluate UFO2 across over 20 real-world Windows applications, demonstrating substantial improvements in robustness and execution accuracy over prior CUAs. Our results show that deep OS integration unlocks a scalable path toward reliable, user-aligned desktop automation.

Auto-bidding, with its strong capability to optimize bidding decisions within dynamic and competitive online environments, has become a pivotal strategy for advertising platforms. Existing approaches typically employ rule-based strategies or Reinforcement Learning (RL) techniques. However, rule-based strategies lack the flexibility to adapt to time-varying market conditions, and RL-based methods struggle to capture essential historical dependencies and observations within Markov Decision Process (MDP) frameworks. Furthermore, these approaches often face challenges in ensuring strategy adaptability across diverse advertising objectives. Additionally, as offline training methods are increasingly adopted to facilitate the deployment and maintenance of stable online strategies, the issues of documented behavioral patterns and behavioral collapse resulting from training on fixed offline datasets become increasingly significant. To address these limitations, this paper introduces a novel offline Generative Auto-bidding framework with Value-Guided Explorations (GAVE). GAVE accommodates various advertising objectives through a score-based Return-To-Go (RTG) module. Moreover, GAVE integrates an action exploration mechanism with an RTG-based evaluation method to explore novel actions while ensuring stability-preserving updates. A learnable value function is also designed to guide the direction of action exploration and mitigate Out-of-Distribution (OOD) problems. Experimental results on two offline datasets and real-world deployments demonstrate that GAVE outperforms state-of-the-art baselines in both offline evaluations and online A/B tests. By applying the core methods of this framework, we proudly secured first place in the NeurIPS 2024 competition, 'AIGB Track: Learning Auto-Bidding Agents with Generative Models'.

Ergodic coverage effectively generates exploratory behaviors for embodied agents by aligning the spatial distribution of the agent's trajectory with a target distribution, where the difference between these two distributions is measured by the ergodic metric. However, existing ergodic coverage methods are constrained by the limited set of ergodic metrics available for control synthesis, fundamentally limiting their performance. In this work, we propose an alternative approach to ergodic coverage based on flow matching, a technique widely used in generative inference for efficient and scalable sampling. We formally derive the flow matching problem for ergodic coverage and show that it is equivalent to a linear quadratic regulator problem with a closed-form solution. Our formulation enables alternative ergodic metrics from generative inference that overcome the limitations of existing ones. These metrics were previously infeasible for control synthesis but can now be supported with no computational overhead. Specifically, flow matching with the Stein variational gradient flow enables control synthesis directly over the score function of the target distribution, improving robustness to the unnormalized distributions; on the other hand, flow matching with the Sinkhorn divergence flow enables an optimal transport-based ergodic metric, improving coverage performance on non-smooth distributions with irregular supports. We validate the improved performance and competitive computational efficiency of our method through comprehensive numerical benchmarks and across different nonlinear dynamics. We further demonstrate the practicality of our method through a series of drawing and erasing tasks on a Franka robot.