Agents
Neuromorphic Computing for Embodied Intelligence in Autonomous Systems: Current Trends, Challenges, and Future Directions
Marchisio, Alberto, Shafique, Muhammad
The growing need for intelligent, adaptive, and energy-efficient autonomous systems across fields such as robotics, mobile agents (e.g., UAVs), and self-driving vehicles is driving interest in neuromorphic computing. By drawing inspiration from biological neural systems, neuromorphic approaches offer promising pathways to enhance the perception, decision-making, and responsiveness of autonomous platforms. This paper surveys recent progress in neuromorphic algorithms, specialized hardware, and cross-layer optimization strategies, with a focus on their deployment in real-world autonomous scenarios. Special attention is given to event-based dynamic vision sensors and their role in enabling fast, efficient perception. The discussion highlights new methods that improve energy efficiency, robustness, adaptability, and reliability through the integration of spiking neural networks into autonomous system architectures. We integrate perspectives from machine learning, robotics, neuroscience, and neuromorphic engineering to offer a comprehensive view of the state of the field. Finally, emerging trends and open challenges are explored, particularly in the areas of real-time decision-making, continual learning, and the development of secure, resilient autonomous systems.
Agentic AI framework for End-to-End Medical Data Inference
Shimgekar, Soorya Ram, Vassef, Shayan, Goyal, Abhay, Kumar, Navin, Saha, Koustuv
--Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce an Agentic AI framework that automates the entire clinical data pipeline, from ingestion to inference, through a system of modular, task-specific agents. These agents are capable of handling both structured and unstructured data, enabling automatic feature selection, model selection, and preprocessing recommendation without manual intervention. We evaluate the system on publicly available datasets from geriatrics, palliative care, and colonoscopy imaging. For example, in the case of structured data (anxiety data) and unstructured data (colonoscopy polyps data), the pipeline begins with file-type detection by the "Ingestion Identifier Agent", followed by the "Data Anonymizer Agent" ensuring privacy compliance, where we first identify what type of data it is and then anonymize it. The "Feature Extraction Agent" then identifies features using an embedding-based approach for tabular data, which gives us all the column names, and a multistage MedGemma-based approach for image data, which gives us the modality and disease name. The "Preprocessing Recommender Agent" and "Preprocessing Implementor Agent" then apply tailored pre-processing based on data type and model requirements. Finally, the "Model Inference Agent" runs the selected model on the user uploaded data and generates interpretable outputs using tools like SHAP, LIME, and DETR attention maps. By automating these high-friction stages of the ML lifecycle, the proposed framework reduces the need for repeated expert intervention, offering a scalable and cost-efficient pathway for operationalizing AI in clinical environments. The integration of Artificial Intelligence (AI) into clinical workflows holds transformative potential for healthcare, enabling timely, data-driven decision-making across diagnosis and treatment planning [1].
Policy Disruption in Reinforcement Learning:Adversarial Attack with Large Language Models and Critical State Identification
Jiang, Junyong, Tian, Buwei, Xu, Chenxing, Li, Songze, Dong, Lu
Reinforcement learning (RL) has achieved remarkable success in fields like robotics and autonomous driving, but adversarial attacks designed to mislead RL systems remain challenging. Existing approaches often rely on modifying the environment or policy, limiting their practicality. This paper proposes an adversarial attack method in which existing agents in the environment guide the target policy to output suboptimal actions without altering the environment. We propose a reward iteration optimization framework that leverages large language models (LLMs) to generate adversarial rewards explicitly tailored to the vulnerabilities of the target agent, thereby enhancing the effectiveness of inducing the target agent toward suboptimal decision-making. Additionally, a critical state identification algorithm is designed to pinpoint the target agent's most vulnerable states, where suboptimal behavior from the victim leads to significant degradation in overall performance. Experimental results in diverse environments demonstrate the superiority of our method over existing approaches.
AlphaGo Moment for Model Architecture Discovery
Liu, Yixiu, Nan, Yang, Xu, Weixian, Hu, Xiangkun, Ye, Lyumanshan, Qin, Zhen, Liu, Pengfei
While AI systems demonstrate exponentially improving capabilities, the pace of AI research itself remains linearly bounded by human cognitive capacity, creating an increasingly severe development bottleneck. We present ASI-Arch, the first demonstration of Artificial Superintelligence for AI research (ASI4AI) in the critical domain of neural architecture discovery--a fully autonomous system that shatters this fundamental constraint by enabling AI to conduct its own architectural innovation. Moving beyond traditional Neural Architecture Search (NAS), which is fundamentally limited to exploring human-defined spaces, we introduce a paradigm shift from automated optimization to automated innovation. ASI-Arch can conduct end-to-end scientific research in the domain of architecture discovery, autonomously hypothesizing novel architectural concepts, implementing them as executable code, training and empirically validating their performance through rigorous experimentation and past experience. ASI-Arch conducted 1,773 autonomous experiments over 20,000 GPU hours, culminating in the discovery of 106 innovative, state-of-the-art (SOTA) linear attention architectures. Like AlphaGo's Move 37 that revealed unexpected strategic insights invisible to human players, our AI-discovered architectures demonstrate emergent design principles that systematically surpass human-designed baselines and illuminate previously unknown pathways for architectural innovation. Crucially, we establish the first empirical scaling law for scientific discovery itself--demonstrating that architectural breakthroughs can be scaled computationally, transforming research progress from a human-limited to a computation-scalable process. We provide comprehensive analysis of the emergent design patterns and autonomous research capabilities that enabled these breakthroughs, establishing a blueprint for self-accelerating AI systems.
Multi-Agent Guided Policy Optimization
Li, Yueheng, Xie, Guangming, Lu, Zongqing
Due to practical constraints such as partial observability and limited communication, Centralized Training with Decentralized Execution (CTDE) has become the dominant paradigm in cooperative Multi-Agent Reinforcement Learning (MARL). However, existing CTDE methods often underutilize centralized training or lack theoretical guarantees. We propose Multi-Agent Guided Policy Optimization (MAGPO), a novel framework that better leverages centralized training by integrating centralized guidance with decentralized execution. MAGPO uses an auto-regressive joint policy for scalable, coordinated exploration and explicitly aligns it with decentralized policies to ensure deployability under partial observability. We provide theoretical guarantees of monotonic policy improvement and empirically evaluate MAGPO on 43 tasks across 6 diverse environments. Results show that MAGPO consistently outperforms strong CTDE baselines and matches or surpasses fully centralized approaches, offering a principled and practical solution for decentralized multi-agent learning. Our code and experimental data can be found in https://github.com/liyheng/MAGPO.
Rapid Modeling Architecture for Lightweight Simulator to Accelerate and Improve Decision Making for Industrial Systems
Designing industrial systems, such as building, improving, and automating distribution centers and manufacturing plants, involves critical decision-making with limited information in the early phases. The lack of information leads to less accurate designs of the systems, which are often difficult to resolve later. It is effective to use simulators to model the designed system and find out the issues early. However, the modeling time required by conventional simulators is too long to allow for rapid model creation to meet decision-making demands. In this paper, we propose a Rapid Modeling Architecture (RMA) for a lightweight industrial simulator that mitigates the modeling burden while maintaining the essential details in order to accelerate and improve decision-making. We have prototyped a simulator based on the RMA and applied it to the actual factory layout design problem. We also compared the modeling time of our simulator to that of an existing simulator, and as a result, our simulator achieved a 78.3% reduction in modeling time compared to conventional simulators.
Technical Implementation of Tippy: Multi-Agent Architecture and System Design for Drug Discovery Laboratory Automation
Fehlis, Yao, Crain, Charles, Jensen, Aidan, Watson, Michael, Juhasz, James, Mandel, Paul, Liu, Betty, Mahon, Shawn, Wilson, Daren, Lynch-Jonely, Nick, Leedom, Ben, Fuller, David
Building on the conceptual framework presented in our previous work on agentic AI for pharmaceutical research, this paper provides a comprehensive technical analysis of Tippy's multi-agent system implementation for drug discovery laboratory automation. We present a distributed microservices architecture featuring five specialized agents (Supervisor, Molecule, Lab, Analysis, and Report) that coordinate through OpenAI Agents SDK orchestration and access laboratory tools via the Model Context Protocol (MCP). The system architecture encompasses agent-specific tool integration, asynchronous communication patterns, and comprehensive configuration management through Git-based tracking. Our production deployment strategy utilizes Kubernetes container orchestration with Helm charts, Docker containerization, and CI/CD pipelines for automated testing and deployment. The implementation integrates vector databases for RAG functionality and employs an Envoy reverse proxy for secure external access. This work demonstrates how specialized AI agents can effectively coordinate complex laboratory workflows while maintaining security, scalability, reliability, and integration with existing laboratory infrastructure through standardized protocols.
Exploring Communication Strategies for Collaborative LLM Agents in Mathematical Problem-Solving
Zhang, Liang, Zhai, Xiaoming, Lin, Jionghao, Lin, Jionghao, Kleiman, Jennifer, Zapata-Rivera, Diego, Forsyth, Carol, Jiang, Yang, Hu, Xiangen, Graesser, Arthur C.
Large Language Model (LLM) agents are increasingly utilized in AI-aided education to support tutoring and learning. Effective communication strategies among LLM agents improve collaborative problem-solving efficiency and facilitate cost-effective adoption in education. However, little research has systematically evaluated the impact of different communication strategies on agents' problem-solving. Our study examines four communication modes, \textit{teacher-student interaction}, \textit{peer-to-peer collaboration}, \textit{reciprocal peer teaching}, and \textit{critical debate}, in a dual-agent, chat-based mathematical problem-solving environment using the OpenAI GPT-4o model. Evaluated on the MATH dataset, our results show that dual-agent setups outperform single agents, with \textit{peer-to-peer collaboration} achieving the highest accuracy. Dialogue acts like statements, acknowledgment, and hints play a key role in collaborative problem-solving. While multi-agent frameworks enhance computational tasks, effective communication strategies are essential for tackling complex problems in AI education.
When Autonomy Goes Rogue: Preparing for Risks of Multi-Agent Collusion in Social Systems
Ren, Qibing, Xie, Sitao, Wei, Longxuan, Yin, Zhenfei, Yan, Junchi, Ma, Lizhuang, Shao, Jing
Recent large-scale events like election fraud and financial scams have shown how harmful coordinated efforts by human groups can be. With the rise of autonomous AI systems, there is growing concern that AI-driven groups could also cause similar harm. While most AI safety research focuses on individual AI systems, the risks posed by multi-agent systems (MAS) in complex real-world situations are still underexplored. In this paper, we introduce a proof-of-concept to simulate the risks of malicious MAS collusion, using a flexible framework that supports both centralized and decentralized coordination structures. We apply this framework to two high-risk fields: misinformation spread and e-commerce fraud. Our findings show that decentralized systems are more effective at carrying out malicious actions than centralized ones. The increased autonomy of decentralized systems allows them to adapt their strategies and cause more damage. Even when traditional interventions, like content flagging, are applied, decentralized groups can adjust their tactics to avoid detection. We present key insights into how these malicious groups operate and the need for better detection systems and countermeasures. Code is available at https://github.com/renqibing/RogueAgent.
Neurodivergent Influenceability as a Contingent Solution to the AI Alignment Problem
Hernández-Espinosa, Alberto, Abrahão, Felipe S., Witkowski, Olaf, Zenil, Hector
The AI alignment problem, which focusses on ensuring that artificial intelligence (AI), including AGI and ASI, systems act according to human values, presents profound challenges. With the progression from narrow AI to Artificial General Intelligence (AGI) and Superintelligence, fears about control and existential risk have escalated. Here, we investigate whether embracing inevitable AI misalignment can be a contingent strategy to foster a dynamic ecosystem of competing agents as a viable path to steer them in more human-aligned trends and mitigate risks. We explore how misalignment may serve and should be promoted as a counterbalancing mechanism to team up with whichever agents are most aligned to human interests, ensuring that no single system dominates destructively. The main premise of our contribution is that misalignment is inevitable because full AI-human alignment is a mathematical impossibility from Turing-complete systems, which we also offer as a proof in this contribution, a feature then inherited to AGI and ASI systems. We introduce a change-of-opinion attack test based on perturbation and intervention analysis to study how humans and agents may change or neutralise friendly and unfriendly AIs through cooperation and competition. We show that open models are more diverse and that most likely guardrails implemented in proprietary models are successful at controlling some of the agents' range of behaviour with positive and negative consequences while closed systems are more steerable and can also be used against proprietary AI systems. We also show that human and AI intervention has different effects hence suggesting multiple strategies.