Optimizing the fuel cycle cost through the optimization of nuclear reactor core loading patterns involves multiple objectives and constraints, leading to a vast number of candidate solutions that cannot be explicitly solved. To advance the state-of-the-art in core reload patterns, we have developed methods based on Deep Reinforcement Learning (DRL) for both single- and multi-objective optimization. Our previous research has laid the groundwork for these approaches and demonstrated their ability to discover high-quality patterns within a reasonable time frame. On the other hand, stochastic optimization (SO) approaches are commonly used in the literature, but there is no rigorous explanation that shows which approach is better in which scenario. In this paper, we demonstrate the advantage of our RL-based approach, specifically using Proximal Policy Optimization (PPO), against the most commonly used SO-based methods: Genetic Algorithm (GA), Parallel Simulated Annealing (PSA) with mixing of states, and Tabu Search (TS), as well as an ensemble-based method, Prioritized Replay Evolutionary and Swarm Algorithm (PESA). We found that the LP scenarios derived in this paper are amenable to a global search to identify promising research directions rapidly, but then need to transition into a local search to exploit these directions efficiently and prevent getting stuck in local optima. PPO adapts its search capability via a policy with learnable weights, allowing it to function as both a global and local search method. Subsequently, we compared all algorithms against PPO in long runs, which exacerbated the differences seen in the shorter cases. Overall, the work demonstrates the statistical superiority of PPO compared to the other considered algorithms.

The design of alloys is a multi-scale problem that requires a holistic approach that involves retrieving relevant knowledge, applying advanced computational methods, conducting experimental validations, and analyzing the results, a process that is typically reserved for human experts. Machine learning (ML) can help accelerate this process, for instance, through the use of deep surrogate models that connect structural features to material properties, or vice versa. However, existing data-driven models often target specific material objectives, offering limited flexibility to integrate out-of-domain knowledge and cannot adapt to new, unforeseen challenges. Here, we overcome these limitations by leveraging the distinct capabilities of multiple AI agents that collaborate autonomously within a dynamic environment to solve complex materials design tasks. The proposed physics-aware generative AI platform, AtomAgents, synergizes the intelligence of large language models (LLM) the dynamic collaboration among AI agents with expertise in various domains, including knowledge retrieval, multi-modal data integration, physics-based simulations, and comprehensive results analysis across modalities that includes numerical data and images of physical simulation results. The concerted effort of the multi-agent system allows for addressing complex materials design problems, as demonstrated by examples that include autonomously designing metallic alloys with enhanced properties compared to their pure counterparts. Our results enable accurate prediction of key characteristics across alloys and highlight the crucial role of solid solution alloying to steer the development of advanced metallic alloys. Our framework enhances the efficiency of complex multi-objective design tasks and opens new avenues in fields such as biomedical materials engineering, renewable energy, and environmental sustainability.

In various industrial fields of human social development, people have been exploring methods aimed at freeing human labor. Constructing LLM-based agents is considered to be one of the most effective tools to achieve this goal. Agent, as a kind of human-like intelligent entity with the ability of perception, planning, decision-making, and action, has created great production value in many fields. However, the bridge O\&M field shows a relatively low level of intelligence compared to other industries. Nevertheless, the bridge O\&M field has developed numerous intelligent inspection devices, machine learning algorithms, and autonomous evaluation and decision-making methods, which provide a feasible basis for breakthroughs in artificial intelligence in this field. The aim of this study is to explore the impact of AI bodies based on large-scale language models on the field of bridge O\&M and to analyze the potential challenges and opportunities it brings to the core tasks of bridge O\&M. Through in-depth research and analysis, this paper expects to provide a more comprehensive perspective for understanding the application of intelligentsia in this field.

Single-cell RNA sequencing (scRNA-seq) data analysis is crucial for biological research, as it enables the precise characterization of cellular heterogeneity. However, manual manipulation of various tools to achieve desired outcomes can be labor-intensive for researchers. To address this, we introduce CellAgent (http://cell.agent4science.cn/), an LLM-driven multi-agent framework, specifically designed for the automatic processing and execution of scRNA-seq data analysis tasks, providing high-quality results with no human intervention. Firstly, to adapt general LLMs to the biological field, CellAgent constructs LLM-driven biological expert roles - planner, executor, and evaluator - each with specific responsibilities. Then, CellAgent introduces a hierarchical decision-making mechanism to coordinate these biological experts, effectively driving the planning and step-by-step execution of complex data analysis tasks. Furthermore, we propose a self-iterative optimization mechanism, enabling CellAgent to autonomously evaluate and optimize solutions, thereby guaranteeing output quality. We evaluate CellAgent on a comprehensive benchmark dataset encompassing dozens of tissues and hundreds of distinct cell types. Evaluation results consistently show that CellAgent effectively identifies the most suitable tools and hyperparameters for single-cell analysis tasks, achieving optimal performance. This automated framework dramatically reduces the workload for science data analyses, bringing us into the "Agent for Science" era.

The ability of Language Models (LMs) to understand natural language makes them a powerful tool for parsing human instructions into task plans for autonomous robots. Unlike traditional planning methods that rely on domain-specific knowledge and handcrafted rules, LMs generalize from diverse data and adapt to various tasks with minimal tuning, acting as a compressed knowledge base. However, LMs in their standard form face challenges with long-horizon tasks, particularly in partially observable multi-agent settings. We propose an LM-based Long-Horizon Planner for Multi-Agent Robotics (LLaMAR), a cognitive architecture for planning that achieves state-of-the-art results in long-horizon tasks within partially observable environments. LLaMAR employs a plan-act-correct-verify framework, allowing self-correction from action execution feedback without relying on oracles or simulators. Additionally, we present MAP-THOR, a comprehensive test suite encompassing household tasks of varying complexity within the AI2-THOR environment. Experiments show that LLaMAR achieves a 30% higher success rate compared to other state-of-the-art LM-based multi-agent planners.

Recent advancements in Large Language Models (LLMs) have led to significant breakthroughs in various natural language processing tasks. However, generating factually consistent responses in knowledge-intensive scenarios remains a challenge due to issues such as hallucination, difficulty in acquiring long-tailed knowledge, and limited memory expansion. This paper introduces SMART, a novel multi-agent framework that leverages external knowledge to enhance the interpretability and factual consistency of LLM-generated responses. SMART comprises four specialized agents, each performing a specific sub-trajectory action to navigate complex knowledge-intensive tasks. We propose a multi-agent co-training paradigm, Long- and Short-Trajectory Learning, which ensures synergistic collaboration among agents while maintaining fine-grained execution by each agent. Extensive experiments on 5 tasks demonstrate SMART's superior performance compared to previous widely adopted methods.

This paper investigates the quality of multi-agent dialogues in simulations powered by Large Language Models (LLMs), focusing on a case study from Park et al. (2023), where 25 agents engage in day-long simulations of life, showcasing complex behaviors and interactions. Analyzing dialogues and memory over multiple sessions revealed significant issues such as repetition, inconsistency, and hallucination, exacerbated by the propagation of erroneous information. To combat these challenges, we propose a novel Screening, Diagnosis, and Regeneration (SDR) framework that detects and corrects utterance errors through a comprehensive process involving immediate issue identification, evidence gathering from past dialogues, and LLM analysis for utterance revision. The effectiveness of the SDR framework is validated through GPT-4 assessments and human evaluations, demonstrating marked improvements in dialogue consistency, diversity, and the reduction of false information. This work presents a pioneering approach to enhancing dialogue quality in multi-agent simulations, establishing a new standard for future research in the field.

We introduce the AutoGRAMS framework for programming multi-step interactions with language models. AutoGRAMS represents AI agents as a graph, where each node can execute either a language modeling instruction or traditional code. Likewise, transitions in the graph can be governed by either language modeling decisions or traditional branch logic. AutoGRAMS supports using variables as memory and allows nodes to call other AutoGRAMS graphs as functions. We show how AutoGRAMS can be used to design highly sophisticated agents, including self-referential agents that can modify their own graph. AutoGRAMS's graph-centric approach aids interpretability, controllability, and safety during the design, development, and deployment of AI agents. We provide our framework as open source at https://github.com/autograms/autograms .

Multi-agent systems (MAS) constitute a significant role in exploring machine intelligence and advanced applications. In order to deeply investigate complicated interactions within MAS scenarios, we originally propose "GNN for MBRL" model, which utilizes a state-spaced Graph Neural Networks with Model-based Reinforcement Learning to address specific MAS missions (e.g., Billiard-Avoidance, Autonomous Driving Cars). In detail, we firstly used GNN model to predict future states and trajectories of multiple agents, then applied the Cross-Entropy Method (CEM) optimized Model Predictive Control to assist the ego-agent planning actions and successfully accomplish certain MAS tasks.

An elusive goal in navigation research is to build an intelligent agent that can understand multimodal instructions including natural language and image, and perform useful navigation. To achieve this, we study a widely useful category of navigation tasks we call Multimodal Instruction Navigation with demonstration Tours (MINT), in which the environment prior is provided through a previously recorded demonstration video. Recent advances in Vision Language Models (VLMs) have shown a promising path in achieving this goal as it demonstrates capabilities in perceiving and reasoning about multimodal inputs. However, VLMs are typically trained to predict textual output and it is an open research question about how to best utilize them in navigation. To solve MINT, we present Mobility VLA, a hierarchical Vision-Language-Action (VLA) navigation policy that combines the environment understanding and common sense reasoning power of long-context VLMs and a robust low-level navigation policy based on topological graphs. The high-level policy consists of a long-context VLM that takes the demonstration tour video and the multimodal user instruction as input to find the goal frame in the tour video. Next, a low-level policy uses the goal frame and an offline constructed topological graph to generate robot actions at every timestep. We evaluated Mobility VLA in a 836m^2 real world environment and show that Mobility VLA has a high end-to-end success rates on previously unsolved multimodal instructions such as "Where should I return this?" while holding a plastic bin. A video demonstrating Mobility VLA can be found here: https://youtu.be/-Tof__Q8_5s