This study addresses key challenges in developing domain-specific large language models (LLMs) for Chinese state-owned assets and enterprises (SOAEs), where current approaches face three limitations: 1) constrained model capacity that limits knowledge integration and cross-task adaptability; 2) excessive reliance on domain-specific supervised fine-tuning (SFT) data, which neglects the broader applicability of general language patterns; and 3) inefficient inference acceleration for large models processing long contexts. In this work, we propose SOAEsV2-7B/72B, a specialized LLM series developed via a three-phase framework: 1) continual pre-training integrates domain knowledge while retaining base capabilities; 2) domain-progressive SFT employs curriculum-based learning strategy, transitioning from weakly relevant conversational data to expert-annotated SOAEs datasets to optimize domain-specific tasks; 3) distillation-enhanced speculative decoding accelerates inference via logit distillation between 72B target and 7B draft models, achieving 1.39-1.52$\times$ speedup without quality loss. Experimental results demonstrate that our domain-specific pre-training phase maintains 99.8% of original general language capabilities while significantly improving domain performance, resulting in a 1.08$\times$ improvement in Rouge-1 score and a 1.17$\times$ enhancement in BLEU-4 score. Ablation studies further show that domain-progressive SFT outperforms single-stage training, achieving 1.02$\times$ improvement in Rouge-1 and 1.06$\times$ in BLEU-4. Our work introduces a comprehensive, full-pipeline approach for optimizing SOAEs LLMs, bridging the gap between general language capabilities and domain-specific expertise.

We present Lay-Your-Scene (shorthand LayouSyn), a novel text-to-layout generation pipeline for natural scenes. Prior scene layout generation methods are either closed-vocabulary or use proprietary large language models for open-vocabulary generation, limiting their modeling capabilities and broader applicability in controllable image generation. In this work, we propose to use lightweight open-source language models to obtain scene elements from text prompts and a novel aspect-aware diffusion Transformer architecture trained in an open-vocabulary manner for conditional layout generation. Extensive experiments demonstrate that LayouSyn outperforms existing methods and achieves state-of-the-art performance on challenging spatial and numerical reasoning benchmarks. Additionally, we present two applications of LayouSyn. First, we show that coarse initialization from large language models can be seamlessly combined with our method to achieve better results. Second, we present a pipeline for adding objects to images, demonstrating the potential of LayouSyn in image editing applications.

Vision Large Language Models (VLLMs) represent a significant advancement in artificial intelligence by integrating image-processing capabilities with textual understanding, thereby enhancing user interactions and expanding application domains. However, their increased complexity introduces novel safety and ethical challenges, particularly in multi-modal and multi-turn conversations. Traditional safety evaluation frameworks, designed for text-based, single-turn interactions, are inadequate for addressing these complexities. To bridge this gap, we introduce the REVEAL (Responsible Evaluation of Vision-Enabled AI LLMs) Framework, a scalable and automated pipeline for evaluating image-input harms in VLLMs. REVEAL includes automated image mining, synthetic adversarial data generation, multi-turn conversational expansion using crescendo attack strategies, and comprehensive harm assessment through evaluators like GPT-4o. We extensively evaluated five state-of-the-art VLLMs, GPT-4o, Llama-3.2, Qwen2-VL, Phi3.5V, and Pixtral, across three important harm categories: sexual harm, violence, and misinformation. Our findings reveal that multi-turn interactions result in significantly higher defect rates compared to single-turn evaluations, highlighting deeper vulnerabilities in VLLMs. Notably, GPT-4o demonstrated the most balanced performance as measured by our Safety-Usability Index (SUI) followed closely by Pixtral. Additionally, misinformation emerged as a critical area requiring enhanced contextual defenses. Llama-3.2 exhibited the highest MT defect rate ($16.55 \%$) while Qwen2-VL showed the highest MT refusal rate ($19.1 \%$).

Training fall detection systems is challenging due to the scarcity of real-world fall data, particularly from elderly individuals. To address this, we explore the potential of Large Language Models (LLMs) for generating synthetic fall data. This study evaluates text-to-motion (T2M, SATO, ParCo) and text-to-text models (GPT4o, GPT4, Gemini) in simulating realistic fall scenarios. We generate synthetic datasets and integrate them with four real-world baseline datasets to assess their impact on fall detection performance using a Long Short-Term Memory (LSTM) model. Additionally, we compare LLM-generated synthetic data with a diffusion-based method to evaluate their alignment with real accelerometer distributions. Results indicate that dataset characteristics significantly influence the effectiveness of synthetic data, with LLM-generated data performing best in low-frequency settings (e.g., 20Hz) while showing instability in high-frequency datasets (e.g., 200Hz). While text-to-motion models produce more realistic biomechanical data than text-to-text models, their impact on fall detection varies. Diffusion-based synthetic data demonstrates the closest alignment to real data but does not consistently enhance model performance. An ablation study further confirms that the effectiveness of synthetic data depends on sensor placement and fall representation. These findings provide insights into optimizing synthetic data generation for fall detection models.

Social Determinants of Health (SDoH) are economic, social and personal circumstances that affect or influence an individual's health status. SDoHs have shown to be correlated to wellness outcomes, and therefore, are useful to physicians in diagnosing diseases and in decision-making. In this work, we automatically extract SDoHs from clinical text using traditional deep learning and Large Language Models (LLMs) to find the advantages and disadvantages of each on an existing publicly available dataset. Our models outperform a previous reference point on a multilabel SDoH classification by 10 points, and we present a method and model to drastically speed up classification (12X execution time) by eliminating expensive LLM processing. The method we present combines a more nimble and efficient solution that leverages the power of the LLM for precision and traditional deep learning methods for efficiency. We also show highly performant results on a dataset supplemented with synthetic data and several traditional deep learning models that outperform LLMs. Our models and methods offer the next iteration of automatic prediction of SDoHs that impact at-risk patients.

Artificial Intelligence (AI) and Large Language Models (LLMs) have rapidly evolved in recent years, showcasing remarkable capabilities in natural language understanding and generation. However, these advancements also raise critical ethical questions regarding safety, potential misuse, discrimination and overall societal impact. This article provides a comparative analysis of the ethical performance of various AI models, including the brand new DeepSeek-V3(R1 with reasoning and without), various GPT variants (4o, 3.5 Turbo, 4 Turbo, o1/o3 mini) and Gemini (1.5 flash, 2.0 flash and 2.0 flash exp) and highlights the need for robust human oversight, especially in situations with high stakes. Furthermore, we present a new metric for calculating harm in LLMs called Relative Danger Coefficient (RDC).

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care delivery. Instant messaging platforms permit clinicians and patients to upload and discuss multimodal medical artifacts seamlessly in medical consultation, but the ability of LLMs to reason over such data while preserving other attributes of competent diagnostic conversation remains unknown. Here we advance the conversational diagnosis and management performance of the Articulate Medical Intelligence Explorer (AMIE) through a new capability to gather and interpret multimodal data, and reason about this precisely during consultations. Leveraging Gemini 2.0 Flash, our system implements a state-aware dialogue framework, where conversation flow is dynamically controlled by intermediate model outputs reflecting patient states and evolving diagnoses. Follow-up questions are strategically directed by uncertainty in such patient states, leading to a more structured multimodal history-taking process that emulates experienced clinicians. We compared AMIE to primary care physicians (PCPs) in a randomized, blinded, OSCE-style study of chat-based consultations with patient actors. We constructed 105 evaluation scenarios using artifacts like smartphone skin photos, ECGs, and PDFs of clinical documents across diverse conditions and demographics. Our rubric assessed multimodal capabilities and other clinically meaningful axes like history-taking, diagnostic accuracy, management reasoning, communication, and empathy. Specialist evaluation showed AMIE to be superior to PCPs on 7/9 multimodal and 29/32 non-multimodal axes (including diagnostic accuracy). The results show clear progress in multimodal conversational diagnostic AI, but real-world translation needs further research.

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of LLM-driven approaches, including symbolic frameworks, generative models, hybrid systems, and multi-agent architectures. We examine techniques such as retrieval-augmented generation, knowledge-graph completion, simulation, causal inference, and tool-assisted reasoning, highlighting trade-offs in interpretability, novelty, and domain alignment. We contrast early symbolic discovery systems (e.g., BACON, KEKADA) with modern LLM pipelines that leverage in-context learning and domain adaptation via fine-tuning, retrieval, and symbolic grounding. For validation, we review simulation, human-AI collaboration, causal modeling, and uncertainty quantification, emphasizing iterative assessment in open-world contexts. The survey maps datasets across biomedicine, materials science, environmental science, and social science, introducing new resources like AHTech and CSKG-600. Finally, we outline a roadmap emphasizing novelty-aware generation, multimodal-symbolic integration, human-in-the-loop systems, and ethical safeguards, positioning LLMs as agents for principled, scalable scientific discovery.

Estimating population parameters in finite populations of text documents can be challenging when obtaining the labels for the target variable requires manual annotation. To address this problem, we combine predictions from a transformer encoder neural network with well-established survey sampling estimators using the model predictions as an auxiliary variable. The applicability is demonstrated in Swedish hate crime statistics based on Swedish police reports. Estimates of the yearly number of hate crimes and the police's under-reporting are derived using the Hansen-Hurwitz estimator, difference estimation, and stratified random sampling estimation. We conclude that if labeled training data is available, the proposed method can provide very efficient estimates with reduced time spent on manual annotation.

This paper presents a comparative benchmark evaluating the performance of Typica.ai's custom Moroccan Darija toxicity detection model against major LLM-based moderation APIs: OpenAI (omni-moderation-latest), Mistral (mistral-moderation-latest), and Anthropic Claude (claude-3-haiku-20240307). We focus on culturally grounded toxic content, including implicit insults, sarcasm, and culturally specific aggression often overlooked by general-purpose systems. Using a balanced test set derived from the OMCD_Typica.ai_Mix dataset, we report precision, recall, F1-score, and accuracy, offering insights into challenges and opportunities for moderation in underrepresented languages. Our results highlight Typica.ai's superior performance, underlining the importance of culturally adapted models for reliable content moderation.