Large Language Models (LLMs) offer new opportunities for the next Point-Of-Interest (POI) prediction task, leveraging their capabilities in semantic understanding of POI trajectories. However, previous LLM-based methods, which are superficially adapted to next POI prediction, largely overlook critical challenges associated with applying LLMs to this task. Specifically, LLMs encounter two critical challenges: (1) a lack of intrinsic understanding of numeric spatiotemporal data, which hinders accurate modeling of users' spatiotemporal distributions and preferences; and (2) an excessively large and unconstrained candidate POI space, which often results in random or irrelevant predictions. To address these issues, we propose a Collaborative Multi Agent Framework for Next POI Prediction, named CoMaPOI. Through the close interaction of three specialized agents (Profiler, Forecaster, and Predictor), CoMaPOI collaboratively addresses the two critical challenges. The Profiler agent is responsible for converting numeric data into language descriptions, enhancing semantic understanding. The Forecaster agent focuses on dynamically constraining and refining the candidate POI space. The Predictor agent integrates this information to generate high-precision predictions. Extensive experiments on three benchmark datasets (NYC, TKY, and CA) demonstrate that CoMaPOI achieves state of the art performance, improving all metrics by 5% to 10% compared to SOTA baselines. This work pioneers the investigation of challenges associated with applying LLMs to complex spatiotemporal tasks by leveraging tailored collaborative agents.

In this paper, we aim to establish a simple, effective, and theoretically grounded benchmark for rigorously probing abstract reasoning in Large Language Models (LLMs). To achieve this, we first develop a mathematic framework that defines abstract reasoning as the ability to: (i) extract essential patterns independent of surface representations, and (ii) apply consistent rules to these abstract patterns. Based on this framework, we introduce two novel complementary metrics: \(\scoreGamma\) measures basic reasoning accuracy, while \(\scoreDelta\) quantifies a model's reliance on specific symbols rather than underlying patterns - a key indicator of true abstraction versus mere memorization. To implement this measurement, we design a benchmark: systematic symbol remapping in rule-based tasks, which forces models to demonstrate genuine pattern recognition beyond superficial token matching. Extensive LLM evaluations using this benchmark (commercial API models, 7B-70B, multi-agent) reveal:1) critical limitations in non-decimal arithmetic and symbolic reasoning; 2) persistent abstraction gaps despite chain-of-thought prompting; and 3) \(\scoreDelta\)'s effectiveness in robustly measuring memory dependence by quantifying performance degradation under symbol remapping, particularly highlighting operand-specific memorization. These findings underscore that current LLMs, despite domain-specific strengths, still lack robust abstract reasoning, highlighting key areas for future improvement.

The intangible cultural heritage (ICH) of China, a cultural asset transmitted across generations by various ethnic groups, serves as a significant testament to the evolution of human civilization and holds irreplaceable value for the preservation of historical lineage and the enhancement of cultural self-confidence. However, the rapid pace of modernization poses formidable challenges to ICH, including threats damage, disappearance and discontinuity of inheritance. China has the highest number of items on the UNESCO Intangible Cultural Heritage List, which is indicative of the nation's abundant cultural resources and emphasises the pressing need for ICH preservation. In recent years, the rapid advancements in large language modelling have provided a novel technological approach for the preservation and dissemination of ICH. This study utilises a substantial corpus of open-source Chinese ICH data to develop a large language model, ICH-Qwen, for the ICH domain. The model employs natural language understanding and knowledge reasoning capabilities of large language models, augmented with synthetic data and fine-tuning techniques. The experimental results demonstrate the efficacy of ICH-Qwen in executing tasks specific to the ICH domain. It is anticipated that the model will provide intelligent solutions for the protection, inheritance and dissemination of intangible cultural heritage, as well as new theoretical and practical references for the sustainable development of intangible cultural heritage. Furthermore, it is expected that the study will open up new paths for digital humanities research.

Recent advancements have shown that the Mixture of Experts (MoE) approach significantly enhances the capacity of large language models (LLMs) and improves performance on downstream tasks. Building on these promising results, multi-modal large language models (MLLMs) have increasingly adopted MoE techniques. However, existing multi-modal MoE tuning methods typically face two key challenges: expert uniformity and router rigidity. Expert uniformity occurs because MoE experts are often initialized by simply replicating the FFN parameters from LLMs, leading to homogenized expert functions and weakening the intended diversification of the MoE architecture. Meanwhile, router rigidity stems from the prevalent use of static linear routers for expert selection, which fail to distinguish between visual and textual tokens, resulting in similar expert distributions for image and text. To address these limitations, we propose EvoMoE, an innovative MoE tuning framework. EvoMoE introduces a meticulously designed expert initialization strategy that progressively evolves multiple robust experts from a single trainable expert, a process termed expert evolution that specifically targets severe expert homogenization. Furthermore, we introduce the Dynamic Token-aware Router (DTR), a novel routing mechanism that allocates input tokens to appropriate experts based on their modality and intrinsic token values. This dynamic routing is facilitated by hypernetworks, which dynamically generate routing weights tailored for each individual token. Extensive experiments demonstrate that EvoMoE significantly outperforms other sparse MLLMs across a variety of multi-modal benchmarks, including MME, MMBench, TextVQA, and POPE. Our results highlight the effectiveness of EvoMoE in enhancing the performance of MLLMs by addressing the critical issues of expert uniformity and router rigidity.

Mitigating social bias in large language models (LLMs) has become an increasingly important research objective. However, existing debiasing methods often incur high human and computational costs, exhibit limited effectiveness, and struggle to scale to larger models and open-ended generation tasks. To address these limitations, this paper proposes BiasFilter, a model-agnostic, inference-time debiasing framework that integrates seamlessly with both open-source and API-based LLMs. Instead of relying on retraining with balanced data or modifying model parameters, BiasFilter enforces fairness by filtering generation outputs in real time. Specifically, it periodically evaluates intermediate outputs every few tokens, maintains an active set of candidate continuations, and incrementally completes generation by discarding low-reward segments based on a fairness reward signal. To support this process, we construct a fairness preference dataset and train an implicit reward model to assess token-level fairness in generated responses. Extensive experiments demonstrate that BiasFilter effectively mitigates social bias across a range of LLMs while preserving overall generation quality.

Retrieving the biological impacts of protein-protein interactions (PPIs) is essential for target identification (Target ID) in drug development. Given the vast number of proteins involved, this process remains time-consuming and challenging. Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) frameworks have supported Target ID; however, no benchmark currently exists for identifying the biological impacts of PPIs. To bridge this gap, we introduce the RAG Benchmark for PPIs (RAGPPI), a factual question-answer benchmark of 4,420 question-answer pairs that focus on the potential biological impacts of PPIs. Through interviews with experts, we identified criteria for a benchmark dataset, such as a type of QA and source. We built a gold-standard dataset (500 QA pairs) through expert-driven data annotation. We developed an ensemble auto-evaluation LLM that reflected expert labeling characteristics, which facilitates the construction of a silver-standard dataset (3,720 QA pairs). We are committed to maintaining RAGPPI as a resource to support the research community in advancing RAG systems for drug discovery QA solutions.

The increasing use of LLMs as substitutes for humans in ``aligning'' LLMs has raised questions about their ability to replicate human judgments and preferences, especially in ambivalent scenarios where humans disagree. This study examines the biases and limitations of LLMs in three roles: answer generator, judge, and debater. These roles loosely correspond to previously described alignment frameworks: preference alignment (judge) and scalable oversight (debater), with the answer generator reflecting the typical setting with user interactions. We develop a ``no-consensus'' benchmark by curating examples that encompass a variety of a priori ambivalent scenarios, each presenting two possible stances. Our results show that while LLMs can provide nuanced assessments when generating open-ended answers, they tend to take a stance on no-consensus topics when employed as judges or debaters. These findings underscore the necessity for more sophisticated methods for aligning LLMs without human oversight, highlighting that LLMs cannot fully capture human disagreement even on topics where humans themselves are divided.

Automated answer grading is a critical challenge in educational technology, with the potential to streamline assessment processes, ensure grading consistency, and provide timely feedback to students. However, existing approaches are often constrained to specific exam formats, lack interpretability in score assignment, and struggle with real-world applicability across diverse subjects and assessment types. To address these limitations, we introduce RATAS (Rubric Automated Tree-based Answer Scoring), a novel framework that leverages state-of-the-art generative AI models for rubric-based grading of textual responses. RATAS is designed to support a wide range of grading rubrics, enable subject-agnostic evaluation, and generate structured, explainable rationales for assigned scores. We formalize the automatic grading task through a mathematical framework tailored to rubric-based assessment and present an architecture capable of handling complex, real-world exam structures. To rigorously evaluate our approach, we construct a unique, contextualized dataset derived from real-world project-based courses, encompassing diverse response formats and varying levels of complexity. Empirical results demonstrate that RATAS achieves high reliability and accuracy in automated grading while providing interpretable feedback that enhances transparency for both students and nstructors.

The rapid evolution of social media has generated an overwhelming volume of user-generated content, conveying implicit opinions and contributing to the spread of misinformation. The method aims to enhance the detection of stance where misinformation can polarize user opinions. Stance detection has emerged as a crucial approach to effectively analyze underlying biases in shared information and combating misinformation. This paper proposes a novel method for \textbf{S}tance \textbf{P}rediction through a \textbf{L}abel-fused dual cross-\textbf{A}ttentive \textbf{E}motion-aware neural \textbf{Net}work (SPLAENet) in misinformative social media user-generated content. The proposed method employs a dual cross-attention mechanism and a hierarchical attention network to capture inter and intra-relationships by focusing on the relevant parts of source text in the context of reply text and vice versa. We incorporate emotions to effectively distinguish between different stance categories by leveraging the emotional alignment or divergence between the texts. We also employ label fusion that uses distance-metric learning to align extracted features with stance labels, improving the method's ability to accurately distinguish between stances. Extensive experiments demonstrate the significant improvements achieved by SPLAENet over existing state-of-the-art methods. SPLAENet demonstrates an average gain of 8.92\% in accuracy and 17.36\% in F1-score on the RumourEval dataset. On the SemEval dataset, it achieves average gains of 7.02\% in accuracy and 10.92\% in F1-score. On the P-stance dataset, it demonstrates average gains of 10.03\% in accuracy and 11.18\% in F1-score. These results validate the effectiveness of the proposed method for stance detection in the context of misinformative social media content.

Deploying large language models (LLMs) in clinical settings faces critical trade-offs: cloud LLMs, with their extensive parameters and superior performance, pose risks to sensitive clinical data privacy, while local LLMs preserve privacy but often fail at complex clinical interpretation tasks. We propose MedOrchestra, a hybrid framework where a cloud LLM decomposes complex clinical tasks into manageable subtasks and prompt generation, while a local LLM executes these subtasks in a privacy-preserving manner. Without accessing clinical data, the cloud LLM generates and validates subtask prompts using clinical guidelines and synthetic test cases. The local LLM executes subtasks locally and synthesizes outputs generated by the cloud LLM. We evaluate MedOrchestra on pancreatic cancer staging using 100 radiology reports under NCCN guidelines. On free-text reports, MedOrchestra achieves 70.21% accuracy, outperforming local model baselines (without guideline: 48.94%, with guideline: 56.59%) and board-certified clinicians (gastroenterologists: 59.57%, surgeons: 65.96%, radiologists: 55.32%). On structured reports, MedOrchestra reaches 85.42% accuracy, showing clear superiority across all settings.