The integration of Large Language Models (LLMs) into various applications has driven the need for structured and reliable responses. A key challenge in Retrieval-Augmented Generation (RAG) systems is ensuring that outputs align with expected formats while minimizing hallucinations. This study examines the role of guided decoding in RAG systems, comparing three methods, Outlines, XGrammar, and LM Format Enforcer, across different multi-turn prompting setups (0-turn, 1-turn, and 2-turn). By evaluating success rates, hallucination rates, and output quality, we provide insights into their performance and applicability. Our findings reveal how multi-turn interactions influence guided decoding, uncovering unexpected performance variations that can inform method selection for specific use cases. This work advances the understanding of structured output generation in RAG systems, offering both theoretical insights and practical guidance for LLM deployment.

We investigated the reproducibility of FairCLIP, proposed by Luo et al. (2024), for improving the group fairness of CLIP (Radford et al., 2021) by minimizing image-text similarity score disparities across sensitive groups using the Sinkhorn distance. The experimental setup of Luo et al. (2024) was reproduced to primarily investigate the research findings for FairCLIP. The model description by Luo et al. (2024) was found to differ from the original implementation. Therefore, a new implementation, A-FairCLIP, is introduced to examine specific design choices. Furthermore, FairCLIP+ is proposed to extend the FairCLIP objective to include multiple attributes. Additionally, the impact of the distance minimization on FairCLIP's fairness and performance was explored. In alignment with the original authors, CLIP was found to be biased towards certain demographics when applied to zero-shot glaucoma classification using medical scans and clinical notes from the Harvard-FairVLMed dataset. However, the experimental results on two datasets do not support their claim that FairCLIP improves the performance and fairness of CLIP. Although the regularization objective reduces Sinkhorn distances, both the official implementation and the aligned implementation, A-FairCLIP, were not found to improve performance nor fairness in zero-shot glaucoma classification.

Link prediction in knowledge graphs requires integrating structural information and semantic context to infer missing entities. While large language models offer strong generative reasoning capabilities, their limited exploitation of structural signals often results in structural sparsity and semantic ambiguity, especially under incomplete or zero-shot settings. To address these challenges, we propose SLiNT (Structure-aware Language model with Injection and coNtrastive Training), a modular framework that injects knowledge-graph-derived structural context into a frozen LLM backbone with lightweight LoRA-based adaptation for robust link prediction. Specifically, Structure-Guided Neighborhood Enhancement (SGNE) retrieves pseudo-neighbors to enrich sparse entities and mitigate missing context; Dynamic Hard Contrastive Learning (DHCL) introduces fine-grained supervision by interpolating hard positives and negatives to resolve entity-level ambiguity; and Gradient-Decoupled Dual Injection (GDDI) performs token-level structure-aware intervention while preserving the core LLM parameters. Experiments on WN18RR and FB15k-237 show that SLiNT achieves superior or competitive performance compared with both embedding-based and generation-based baselines, demonstrating the effectiveness of structure-aware representation learning for scalable knowledge graph completion.

Adapting large language models (LLMs) to specific domains often faces a critical bottleneck: the scarcity of high-quality, human-curated data. While large volumes of unchecked data are readily available, indiscriminately using them for fine-tuning risks introducing noise and degrading performance. Strategic data selection is thus crucial, requiring a method that is both accurate and efficient. Existing approaches, categorized as similarity-based and direct optimization methods, struggle to simultaneously achieve these goals. In this paper, we introduce LAMDAS (LLM As an iMplicit classifier for domain-specific DAta Selection), a novel approach that leverages the pre-trained LLM itself as an implicit classifier, thereby bypassing explicit feature engineering and computationally intensive optimization process. LAMDAS reframes data selection as a one-class classification problem, identifying candidate data that "belongs" to the target domain defined by a small reference dataset. Extensive experimental results demonstrate that LAMDAS not only exceeds the performance of full-data training using a fraction of the data but also outperforms nine state-of-the-art (SOTA) baselines under various scenarios. Furthermore, LAMDAS achieves the most compelling balance between performance gains and computational efficiency compared to all evaluated baselines.

Transformer-based language models traditionally use uniform (isotropic) layer sizes, yet they ignore the diverse functional roles that different depths can play and their computational capacity needs. Building on Layer-Wise Scaling (LWS) and pruning literature, we introduce three new LWS variants - Framed, Reverse, and Crown - that redistribute FFN widths and attention heads via two or three-point linear interpolation in the pre-training stage. We present the first systematic ablation of LWS and its variants, on a fixed budget of 180M parameters, trained on 5B tokens. All models converge to similar losses and achieve better performance compared to an equal-cost isotropic baseline, without a substantial decrease in training throughput. This work represents an initial step into the design space of layer-wise architectures for pre-training, but future work should scale experiments to orders of magnitude more tokens and parameters to fully assess their potential.

The cycle of scientific discovery is frequently bottlenecked by the slow, manual creation of software to support computational experiments. To address this, we present an AI system that creates expert-level scientific software whose goal is to maximize a quality metric. The system uses a Large Language Model (LLM) and Tree Search (TS) to systematically improve the quality metric and intelligently navigate the large space of possible solutions. The system achieves expert-level results when it explores and integrates complex research ideas from external sources. The effectiveness of tree search is demonstrated across a wide range of benchmarks. In bioinformatics, it discovered 40 novel methods for single-cell data analysis that outperformed the top human-developed methods on a public leaderboard. In epidemiology, it generated 14 models that outperformed the CDC ensemble and all other individual models for forecasting COVID-19 hospitalizations. Our method also produced state-of-the-art software for geospatial analysis, neural activity prediction in zebrafish, time series forecasting and numerical solution of integrals. By devising and implementing novel solutions to diverse tasks, the system represents a significant step towards accelerating scientific progress.

Centralized RAG pipelines struggle with heterogeneous and privacy-sensitive data, especially in distributed healthcare settings where patient data spans SQL, knowledge graphs, and clinical notes. Clinicians face difficulties retrieving rare disease cases due to privacy constraints and the limitations of traditional cloud-based RAG systems in handling diverse formats and edge devices. To address this, we introduce HyFedRAG, a unified and efficient Federated RAG framework tailored for Hybrid data modalities. By leveraging an edge-cloud collaborative mechanism, HyFedRAG enables RAG to operate across diverse data sources while preserving data privacy. Our key contributions are: (1) We design an edge-cloud collaborative RAG framework built on Flower, which supports querying structured SQL data, semi-structured knowledge graphs, and unstructured documents. The edge-side LLMs convert diverse data into standardized privacy-preserving representations, and the server-side LLMs integrates them for global reasoning and generation. (2) We integrate lightweight local retrievers with privacy-aware LLMs and provide three anonymization tools that enable each client to produce semantically rich, de-identified summaries for global inference across devices. (3) To optimize response latency and reduce redundant computation, we design a three-tier caching strategy consisting of local cache, intermediate representation cache, and cloud inference cache. Experimental results on PMC-Patients demonstrate that HyFedRAG outperforms existing baselines in terms of retrieval quality, generation consistency, and system efficiency. Our framework offers a scalable and privacy-compliant solution for RAG over structural-heterogeneous data, unlocking the potential of LLMs in sensitive and diverse data environments.

Recent progress in vision-language models (VLMs) has led to impressive results in document understanding tasks, but their high computational demands remain a challenge. To mitigate the compute burdens, we propose a lightweight token pruning framework that filters out non-informative background regions from document images prior to VLM processing. A binary patch-level classifier removes non-text areas, and a max-pooling refinement step recovers fragmented text regions to enhance spatial coherence. Experiments on real-world document datasets demonstrate that our approach substantially lowers computational costs, while maintaining comparable accuracy.

This study presents DiagCoT, a multi-stage framework that applies supervised fine-tuning to general-purpose vision-language models (VLMs) to emulate radiologists' stepwise diagnostic reasoning using only free-text reports. DiagCoT combines contrastive image-report tuning for domain alignment, chain-of-thought supervision to capture inferential logic, and reinforcement tuning with clinical reward signals to enhance factual accuracy and fluency. On the MIMIC-CXR benchmark, DiagCoT improved zero-shot disease classification AUC from 0.52 to 0.76 (absolute gain of 0.24), pathology grounding mIoU from 0.08 to 0.31 (absolute gain of 0.23), and report generation BLEU from 0.11 to 0.33 (absolute gain of 0.22). It outperformed state-of-the-art models including LLaVA-Med and CXR-LLAVA on long-tailed diseases and external datasets. By converting unstructured clinical narratives into structured supervision, DiagCoT offers a scalable approach for developing interpretable and diagnostically competent AI systems for radiology.

This paper explores the multilingual commonsense generation abilities of Large Language Models (LLMs). To facilitate this investigation, we introduce MULTICOM, a novel benchmark that extends the COCOTEROS dataset to four languages: English, Spanish, Dutch, and Valencian. The task involves generating a commonsensical sentence that includes a given triplet of words. We evaluate a range of open-source LLMs, including LLaMA, Qwen, Gemma, EuroLLM, and Salamandra, on this benchmark. Our evaluation combines automatic metrics, LLM-as-a-judge approaches (using Prometheus and JudgeLM), and human annotations. Results consistently show superior performance in English, with significantly lower performance in less-resourced languages. While contextual support yields mixed results, it tends to benefit underrepresented languages. These findings underscore the current limitations of LLMs in multilingual commonsense generation. The dataset is publicly available at https://huggingface.co/datasets/gplsi/MULTICOM.