Transfer learning methods start performing poorly when the complexity of the learning task is increased. Most of these methods calculate the cumulative differences of all the matched features and then use them to back-propagate that loss through all the layers. Contrary to these methods, in this work, we propose a novel layer-wise learning scheme that adjusts learning parameters per layer as a function of the differences in the Jacobian/Attention/Hessian of the output activations w.r.t. the network parameters. We applied this novel scheme for attention map-based and derivative-based (first and second order) transfer learning methods. We received improved learning performance and stability against a wide range of datasets. From extensive experimental evaluation, we observed that the performance boost achieved by our method becomes more significant with the increasing difficulty of the learning task.

Pre-trained models have become pivotal in enhancing the efficiency and accuracy of time series forecasting on target data sets by leveraging transfer learning. While benchmarks validate the performance of model generalization on various target data sets, there is no structured research providing similarity and diversity measures to explain which characteristics of source and target data lead to transfer learning success. Our study pioneers in systematically evaluating the impact of source-target similarity and source diversity on zero-shot and fine-tuned forecasting outcomes in terms of accuracy, bias, and uncertainty estimation. We investigate these dynamics using pre-trained neural networks across five public source datasets, applied to forecasting five target data sets, including real-world wholesales data. We identify two feature-based similarity and diversity measures, finding that source-target similarity reduces forecasting bias, while source diversity improves forecasting accuracy and uncertainty estimation, but increases the bias.

Clinical and biomedical research in low-resource settings often faces significant challenges due to the need for high-quality data with sufficient sample sizes to construct effective models. These constraints hinder robust model training and prompt researchers to seek methods for leveraging existing knowledge from related studies to support new research efforts. Transfer learning (TL), a machine learning technique, emerges as a powerful solution by utilizing knowledge from pre-trained models to enhance the performance of new models, offering promise across various healthcare domains. Despite its conceptual origins in the 1990s, the application of TL in medical research has remained limited, especially beyond image analysis. In our review of TL applications in structured clinical and biomedical data, we screened 3,515 papers, with 55 meeting the inclusion criteria. Among these, only 2% (one out of 55) utilized external studies, and 7% (four out of 55) addressed scenarios involving multi-site collaborations with privacy constraints. To achieve actionable TL with structured medical data while addressing regional disparities, inequality, and privacy constraints in healthcare research, we advocate for the careful identification of appropriate source data and models, the selection of suitable TL frameworks, and the validation of TL models with proper baselines.

In industrial recommendation systems, there are several mini-apps designed to meet the diverse interests and needs of users. The sample space of them is merely a small subset of the entire space, making it challenging to train an efficient model. In recent years, there have been many excellent studies related to cross-domain recommendation aimed at mitigating the problem of data sparsity. However, few of them have simultaneously considered the adaptability of both sample and representation continual transfer setting to the target task. To overcome the above issue, we propose a Entire space Continual and Adaptive Transfer learning framework called ECAT which includes two core components: First, as for sample transfer, we propose a two-stage method that realizes a coarse-to-fine process. Specifically, we perform an initial selection through a graph-guided method, followed by a fine-grained selection using domain adaptation method. Second, we propose an adaptive knowledge distillation method for continually transferring the representations from a model that is well-trained on the entire space dataset. ECAT enables full utilization of the entire space samples and representations under the supervision of the target task, while avoiding negative migration. Comprehensive experiments on real-world industrial datasets from Taobao show that ECAT advances state-of-the-art performance on offline metrics, and brings +13.6% CVR and +8.6% orders for Baiyibutie, a famous mini-app of Taobao.

Recent successes suggest that parameter-efficient fine-tuning of foundation models as the state-of-the-art method for transfer learning in vision, replacing the rich literature of alternatives such as meta-learning. In trying to harness the best of both worlds, meta-tuning introduces a subsequent optimization stage of foundation models but has so far only shown limited success and crucially tends to underperform on out-of-distribution (OOD) tasks. In this paper, we introduce Sparse MetA-Tuning (SMAT), a method inspired by sparse mixture-of-experts approaches and trained to isolate subsets of pre-trained parameters automatically for meta-tuning on each task. SMAT successfully overcomes OOD sensitivity and delivers on the promise of enhancing the transfer abilities of vision foundation models beyond parameter-efficient fine-tuning. We establish new state-of-the-art results on a challenging combination of Meta-Dataset augmented with additional OOD tasks in both zero-shot and gradient-based adaptation settings. In addition, we provide a thorough analysis of the superiority of learned over hand-designed sparsity patterns for sparse expert methods and the pivotal importance of the sparsity level in balancing between in-distribution and out-of-distribution generalization. Our code is publicly available.

Identifying misogyny using artificial intelligence is a form of combating online toxicity against women. However, the subjective nature of interpreting misogyny poses a significant challenge to model the phenomenon. In this paper, we propose a multitask learning approach that leverages the subjectivity of this task to enhance the performance of the misogyny identification systems. We incorporated diverse perspectives from annotators in our model design, considering gender and age across six profile groups, and conducted extensive experiments and error analysis using two language models to validate our four alternative designs of the multitask learning technique to identify misogynistic content in English tweets. The results demonstrate that incorporating various viewpoints enhances the language models' ability to interpret different forms of misogyny. This research advances content moderation and highlights the importance of embracing diverse perspectives to build effective online moderation systems.

Air pollution, especially particulate matter 2.5 (PM2.5), is a pressing concern for public health and is difficult to estimate in developing countries (data-poor regions) due to a lack of ground sensors. Transfer learning models can be leveraged to solve this problem, as they use alternate data sources to gain knowledge (i.e., data from data-rich regions). However, current transfer learning methodologies do not account for dependencies between the source and the target domains. We recognize this transfer problem as spatial transfer learning and propose a new feature named Latent Dependency Factor (LDF) that captures spatial and semantic dependencies of both domains and is subsequently added to the feature spaces of the domains. We generate LDF using a novel two-stage autoencoder model that learns from clusters of similar source and target domain data. Our experiments show that transfer learning models using LDF have a 19.34% improvement over the baselines. We additionally support our experiments with qualitative findings.

Biological sequences encode fundamental instructions for the building blocks of life, in the form of DNA, RNA, and proteins. Modeling these sequences is key to understand disease mechanisms and is an active research area in computational biology. Recently, Large Language Models have shown great promise in solving certain biological tasks but current approaches are limited to a single sequence modality (DNA, RNA, or protein). Key problems in genomics intrinsically involve multiple modalities, but it remains unclear how to adapt general-purpose sequence models to those cases. In this work we propose a multi-modal model that connects DNA, RNA, and proteins by leveraging information from different pre-trained modality-specific encoders. We demonstrate its capabilities by applying it to the largely unsolved problem of predicting how multiple RNA transcript isoforms originate from the same gene (i.e. same DNA sequence) and map to different transcription expression levels across various human tissues. We show that our model, dubbed IsoFormer, is able to accurately predict differential transcript expression, outperforming existing methods and leveraging the use of multiple modalities. Our framework also achieves efficient transfer knowledge from the encoders pre-training as well as in between modalities. We open-source our model, paving the way for new multi-modal gene expression approaches.

This paper establishes the generalization error of pooled min-$\ell_2$-norm interpolation in transfer learning where data from diverse distributions are available. Min-norm interpolators emerge naturally as implicit regularized limits of modern machine learning algorithms. Previous work characterized their out-of-distribution risk when samples from the test distribution are unavailable during training. However, in many applications, a limited amount of test data may be available during training, yet properties of min-norm interpolation in this setting are not well-understood. We address this gap by characterizing the bias and variance of pooled min-$\ell_2$-norm interpolation under covariate and model shifts. The pooled interpolator captures both early fusion and a form of intermediate fusion. Our results have several implications: under model shift, for low signal-to-noise ratio (SNR), adding data always hurts. For higher SNR, transfer learning helps as long as the shift-to-signal (SSR) ratio lies below a threshold that we characterize explicitly. By consistently estimating these ratios, we provide a data-driven method to determine: (i) when the pooled interpolator outperforms the target-based interpolator, and (ii) the optimal number of target samples that minimizes the generalization error. Under covariate shift, if the source sample size is small relative to the dimension, heterogeneity between between domains improves the risk, and vice versa. We establish a novel anisotropic local law to achieve these characterizations, which may be of independent interest in random matrix theory. We supplement our theoretical characterizations with comprehensive simulations that demonstrate the finite-sample efficacy of our results.

Skin cancer is one of the most common and deadliest types of cancer. Early diagnosis of skin cancer at a benign stage is critical to reducing cancer mortality. To detect skin cancer at an earlier stage an automated system is compulsory that can save the life of many patients. Many previous studies have addressed the problem of skin cancer diagnosis using various deep learning and transfer learning models. However, existing literature has limitations in its accuracy and time-consuming procedure. In this work, we applied five different pre-trained transfer learning approaches for binary classification of skin cancer detection at benign and malignant stages. To increase the accuracy of these models we fine-tune different layers and activation functions. We used a publicly available ISIC dataset to evaluate transfer learning approaches. For model stability, data augmentation techniques are applied to improve the randomness of the input dataset. These approaches are evaluated using different hyperparameters such as batch sizes, epochs, and optimizers. The experimental results show that the ResNet-50 model provides an accuracy of 0.935, F1-score of 0.86, and precision of 0.94.