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However, very few studies provide clinically informative measures to aid in decision-making and resource allocation. Head-to-head comparison of neuroimaging-based multivariate classifiers is an essential first step to promote translation of these tools to clinical practice. Gray matter (GM) and white matter images were used as inputs into a support vector machine to classify patients and control subjects. This will not only promote the search for an optimum diagnostic tool but also aid in the translation of neuroimaging to clinical use.


Clinical Utility of Machine-Learning Approaches in Schizophrenia: Improving Diagnostic Confidence for Translational Neuroimaging

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Machine-learning approaches are becoming commonplace in the neuroimaging literature as potential diagnostic and prognostic tools for the study of clinical populations. However, very few studies provide clinically informative measures to aid in decision-making and resource allocation. Head-to-head comparison of neuroimaging-based multivariate classifiers is an essential first step to promote translation of these tools to clinical practice. We systematically evaluated the classifier performance using back-to-back structural MRI in two field strengths (3- and 7-T) to discriminate patients with schizophrenia (n 19) from healthy controls (n 20). Gray matter (GM) and white matter images were used as inputs into a support vector machine to classify patients and control subjects.


Time-Contrastive Learning for Latent Variable Models

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"Aapo did it again!" - I exclaimed while reading this paper yesterday on the train back home (or at least I thought I was going home until I realised I was sitting on the wrong train the whole time. This gave me a couple more hours to think while traveling on a variety of long-distance buses...) Aapo Hyvärinen is one of my heroes - he did tons of cool work, probably most famous for pseudo-likelihood, score matching and ICA. Time-contrastive learning (TCL) is a technique for learning to extract nonlinear representations from time series data. First, the time series is sliced up into a number of non-overlapping chunks, indexed by \tau . Then, a multivariate logistic regression classifier is trained in a supervised manner to look at a sample taken from the series at an unknown time and predict \tau, the index of the chunk it came from.


On the Application of Support Vector Machines to the Prediction of Propagation Losses at 169 MHz for Smart Metering Applications

arXiv.org Machine Learning

Recently, the need of deploying new wireless networks for smart gas metering has raised the problem of radio planning in the169 MHz band. Unluckily, software tools commonly adopted for radio planning in cellular communication systems cannot be employed to solve this problem because of the substantially lower transmission frequencies characterizing this application. In this manuscript a novel data-centric solution, based on the use of support vector machine techniques for classification and regression, is proposed. Our method requires the availability of a limited set of received signal strength measurements and the knowledge of a three-dimensional map of the propagation environment of interest, and generates both an estimate of the coverage area and a prediction of the field strength within it. Numerical results referring to different Italian villages and cities evidence that our method is able to achieve good accuracy at the price of an acceptable computational cost and of a limited effort for the acquisition of measurements in the considered environments.


Geometric Mean Metric Learning

arXiv.org Machine Learning

We revisit the task of learning a Euclidean metric from data. We approach this problem from first principles and formulate it as a surprisingly simple optimization problem. Indeed, our formulation even admits a closed form solution. This solution possesses several very attractive properties: (i) an innate geometric appeal through the Riemannian geometry of positive definite matrices; (ii) ease of interpretability; and (iii) computational speed several orders of magnitude faster than the widely used LMNN and ITML methods. Furthermore, on standard benchmark datasets, our closed-form solution consistently attains higher classification accuracy.


On the use of Harrell's C for clinical risk prediction via random survival forests

arXiv.org Machine Learning

Random survival forests (RSF) are a powerful method for risk prediction of right-censored outcomes in biomedical research. RSF use the log-rank split criterion to form an ensemble of survival trees. The most common approach to evaluate the prediction accuracy of a RSF model is Harrell's concordance index for survival data ('C index'). Conceptually, this strategy implies that the split criterion in RSF is different from the evaluation criterion of interest. This discrepancy can be overcome by using Harrell's C for both node splitting and evaluation. We compare the difference between the two split criteria analytically and in simulation studies with respect to the preference of more unbalanced splits, termed end-cut preference (ECP). Specifically, we show that the log-rank statistic has a stronger ECP compared to the C index. In simulation studies and with the help of two medical data sets we demonstrate that the accuracy of RSF predictions, as measured by Harrell's C, can be improved if the log-rank statistic is replaced by the C index for node splitting. This is especially true in situations where the censoring rate or the fraction of informative continuous predictor variables is high. Conversely, log-rank splitting is preferable in noisy scenarios. Both C-based and log-rank splitting are implemented in the R~package ranger. We recommend Harrell's C as split criterion for use in smaller scale clinical studies and the log-rank split criterion for use in large-scale 'omics' studies.


How a Technical Co-founder Spends his Time: Minute-by-minute Data for a Year

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I'm co-founder and CTO at Overleaf, a successful SaaS startup based in London. From August 2014 to December 2015, I manually tracked all of my work time, minute-by-minute, and analysed the data in R. Like most people who track their time, my goal was to improve my productivity. It gave me data to answer questions about whether I was spending too much or too little time on particular activities, for example user support or client projects. The data showed that my intuition on these questions was often wrong. There were also some less tangible benefits. It was reassuring on a Friday to have an answer to that usually rhetorical question, "where did this week go?" I feel like it also reduced context switching: if I stopped what I was doing to answer an chat message or email, I had to take the time to record it in my time tracker. I think this added friction was a win for overall productivity, perhaps paradoxically. This post documents the (simple) system I built to record my time, how I analysed the data, and the results.


How an e-retailer employs machine-learning to reduce customer churn - RTInsights

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How an ecommerce company used predictive analytics to improve customer retention. Acquiring new customers is much more expensive than retaining current ones. Keeping customers from unsubscribing from a company's services or from choosing another company's solution is therefore a challenge that should be at the top of every corporate agenda. A way to address this challenge is through predictive customer churn prevention, in which data is used to find out which customers are likely to churn in order to win them back -- before they are gone. Showroomprivé.com, an ecommerce company founded in 2006, sought ways to employ machine learning approaches to retain more customers.


GP-select: Accelerating EM using adaptive subspace preselection

arXiv.org Machine Learning

We propose a nonparametric procedure to achieve fast inference in generative graphical models when the number of latent states is very large. The approach is based on iterative latent variable preselection, where we alternate between learning a 'selection function' to reveal the relevant latent variables, and use this to obtain a compact approximation of the posterior distribution for EM; this can make inference possible where the number of possible latent states is e.g. exponential in the number of latent variables, whereas an exact approach would be computationally unfeasible. We learn the selection function entirely from the observed data and current EM state via Gaussian process regression. This is by contrast with earlier approaches, where selection functions were manually-designed for each problem setting. We show that our approach performs as well as these bespoke selection functions on a wide variety of inference problems: in particular, for the challenging case of a hierarchical model for object localization with occlusion, we achieve results that match a customized state-of-the-art selection method, at a far lower computational cost.


Low Gasoline Prices, What are Consumers Doing with the Extra Cash? – Data Science Central

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She is currently in the NYC Data Science Academy 12 week full time Data Science Bootcamp program taking place between April 11th to July 1st, 2016. This post is based on her third class project - Web Scraping, due on the 6th week of the program. Oil prices have fallen sharply since the summer of 2014. Prices bottomed in February 2016, since then they have gradually increased. While the breakeven cost is a popular topic among investors, on the consumer side gasoline prices are very cheap.