"Is it possible to predict expression levels of different genes at a given spatial location in the routine histology image of a tumor section by modeling its stain absorption characteristics?" In this work, we propose a "stain-aware" machine learning approach for prediction of spatial transcriptomic gene expression profiles using digital pathology image of a routine Hematoxylin & Eosin (H&E) histology section. Unlike recent deep learning methods which are used for gene expression prediction, our proposed approach termed Neural Stain Learning (NSL) explicitly models the association of stain absorption characteristics of the tissue with gene expression patterns in spatial transcriptomics by learning a problem-specific stain deconvolution matrix in an end-to-end manner. The proposed method with only 11 trainable weight parameters outperforms both classical regression models with cellular composition and morphological features as well as deep learning methods. We have found that the gene expression predictions from the proposed approach show higher correlations with true expression values obtained through sequencing for a larger set of genes in comparison to other approaches.

A structured variable selection problem is considered in which the covariates, divided into predefined groups, activate according to sparse patterns with few nonzero entries per group. Capitalizing on the concept of atomic norm, a composite norm can be properly designed to promote such exclusive group sparsity patterns. The resulting norm lends itself to efficient and flexible regularized optimization algorithms for support recovery, like the proximal algorithm. Moreover, an active set algorithm is proposed that builds the solution by successively including structure atoms into the estimated support. It is also shown that such an algorithm can be tailored to match more rigid structures than plain exclusive group sparsity. Asymptotic consistency analysis (with both the number of parameters as well as the number of groups growing with the observation size) establishes the effectiveness of the proposed solution in terms of signed support recovery under conventional assumptions.

We explore the ability of overparameterized shallow neural networks to learn Lipschitz regression functions with and without label noise when trained by Gradient Descent (GD). To avoid the problem that in the presence of noisy labels, neural networks trained to nearly zero training error are inconsistent on this class, we propose an early stopping rule that allows us to show optimal rates. This provides an alternative to the result of Hu et al. (2021) who studied the performance of $\ell 2$ -regularized GD for training shallow networks in nonparametric regression which fully relied on the infinite-width network (Neural Tangent Kernel (NTK)) approximation. Here we present a simpler analysis which is based on a partitioning argument of the input space (as in the case of 1-nearest-neighbor rule) coupled with the fact that trained neural networks are smooth with respect to their inputs when trained by GD. In the noise-free case the proof does not rely on any kernelization and can be regarded as a finite-width result. In the case of label noise, by slightly modifying the proof, the noise is controlled using a technique of Yao, Rosasco, and Caponnetto (2007).

The increasing size of data generated by smartphones and IoT devices motivated the development of Federated Learning (FL), a framework for on-device collaborative training of machine learning models. First efforts in FL focused on learning a single global model with good average performance across clients, but the global model may be arbitrarily bad for a given client, due to the inherent heterogeneity of local data distributions. Federated multi-task learning (MTL) approaches can learn personalized models by formulating an opportune penalized optimization problem. The penalization term can capture complex relations among personalized models, but eschews clear statistical assumptions about local data distributions. In this work, we propose to study federated MTL under the flexible assumption that each local data distribution is a mixture of unknown underlying distributions. This assumption encompasses most of the existing personalized FL approaches and leads to federated EM-like algorithms for both client-server and fully decentralized settings. Moreover, it provides a principled way to serve personalized models to clients not seen at training time. The algorithms' convergence is analyzed through a novel federated surrogate optimization framework, which can be of general interest. Experimental results on FL benchmarks show that in most cases our approach provides models with higher accuracy and fairness than state-of-the-art methods.

Cricket is unarguably one of the most popular sports in the world. Predicting the outcome of a cricket match has become a fundamental problem as we are advancing in the field of machine learning. Multiple researchers have tried to predict the outcome of a cricket match or a tournament, or to predict the performance of players during a match, or to predict the players who should be selected as per their current performance, form, morale, etc. using machine learning and artificial intelligence techniques keeping in mind extensive detailing, features, and parameters. We discuss some of these techniques along with a brief comparison among these techniques.

In recent years, inductive graph embedding models, \emph{viz.}, graph neural networks (GNNs) have become increasingly accurate at link prediction (LP) in online social networks. The performance of such networks depends strongly on the input node features, which vary across networks and applications. Selecting appropriate node features remains application-dependent and generally an open question. Moreover, owing to privacy and ethical issues, use of personalized node features is often restricted. In fact, many publicly available data from online social network do not contain any node features (e.g., demography). In this work, we provide a comprehensive experimental analysis which shows that harnessing a transductive technique (e.g., Node2Vec) for obtaining initial node representations, after which an inductive node embedding technique takes over, leads to substantial improvements in link prediction accuracy. We demonstrate that, for a wide variety of GNN variants, node representation vectors obtained from Node2Vec serve as high quality input features to GNNs, thereby improving LP performance.

Accurate detection of a drivers attention state can help develop assistive technologies that respond to unexpected hazards in real time and therefore improve road safety. This study compares the performance of several attention classifiers trained on participants brain activity. Participants performed a driving task in an immersive simulator where the car randomly deviated from the cruising lane. They had to correct the deviation and their response time was considered as an indicator of attention level. Participants repeated the task in two sessions; in one session they received kinesthetic feedback and in another session no feedback. Using their EEG signals, we trained three attention classifiers; a support vector machine (SVM) using EEG spectral band powers, and a Convolutional Neural Network (CNN) using either spectral features or the raw EEG data. Our results indicated that the CNN model trained on raw EEG data obtained under kinesthetic feedback achieved the highest accuracy (89%). While using a participants own brain activity to train the model resulted in the best performances, inter-subject transfer learning still performed high (75%), showing promise for calibration-free Brain-Computer Interface (BCI) systems. Our findings show that CNN and raw EEG signals can be employed for effective training of a passive BCI for real-time attention classification.

As the world is rapidly moving towards digitization and money transactions are becoming cashless, the use of credit cards has rapidly increased. The fraud activities associated with it have also been increasing which leads to a huge loss to the financial institutions. Therefore, we need to analyze and detect the fraudulent transaction from the non-fraudulent ones. In this paper, we present a comprehensive review of various methods used to detect credit card fraud. These methodologies include Hidden Markov Model, Decision Trees, Logistic Regression, Support Vector Machines (SVM), Genetic algorithm, Neural Networks, Random Forests, Bayesian Belief Network. A comprehensive analysis of various techniques is presented. We conclude the paper with the pros and cons of the same as stated in the respective papers.

Stuttering is a speech disorder which impacts the personal and professional lives of millions of people worldwide. To save themselves from stigma and discrimination, people who stutter (PWS) may adopt different strategies to conceal their stuttering. One of the common strategies is word substitution where an individual avoids saying a word they might stutter on and use an alternative instead. This process itself can cause stress and add more burden. In this work, we present Fluent, an AI augmented writing tool which assists PWS in writing scripts which they can speak more fluently. Fluent embodies a novel active learning based method of identifying words an individual might struggle pronouncing. Such words are highlighted in the interface. On hovering over any such word, Fluent presents a set of alternative words which have similar meaning but are easier to speak. The user is free to accept or ignore these suggestions. Based on such user interaction (feedback), Fluent continuously evolves its classifier to better suit the personalized needs of each user. We evaluated our tool by measuring its ability to identify difficult words for 10 simulated users. We found that our tool can identify difficult words with a mean accuracy of over 80% in under 20 interactions and it keeps improving with more feedback. Our tool can be beneficial for certain important life situations like giving a talk, presentation, etc. The source code for this tool has been made publicly accessible at github.com/bhavyaghai/Fluent.

As you can see, Isomap is an Unsupervised Machine Learning technique aimed at Dimensionality Reduction. It differs from a few other techniques in the same category by using a non-linear approach to dimensionality reduction instead of linear mappings used by algorithms such as PCA. We will see how linear vs. non-linear approaches differ in the next section. Isomap is a technique that combines several different algorithms, enabling it to use a non-linear way to reduce dimensions while preserving local structures. Before we look at the example of Isomap and compare it to a linear method of Principal Components Analysis (PCA), let's list the high-level steps that Isomap performs: For our example, let's create a 3D object known as a Swiss roll.