The timely identification of significant memory concern (SMC) is crucial for proactive cognitive health management, especially in an aging population. Detecting SMC early enables timely intervention and personalized care, potentially slowing cognitive disorder progression. This study presents a state-of-the-art review followed by a comprehensive evaluation of machine learning models within the randomized neural networks (RNNs) and hyperplane-based classifiers (HbCs) family to investigate SMC diagnosis thoroughly. Utilizing the Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2) dataset, 111 individuals with SMC and 111 healthy older adults are analyzed based on T1W magnetic resonance imaging (MRI) scans, extracting rich features. This analysis is based on baseline structural MRI (sMRI) scans, extracting rich features from gray matter (GM), white matter (WM), Jacobian determinant (JD), and cortical thickness (CT) measurements. In RNNs, deep random vector functional link (dRVFL) and ensemble dRVFL (edRVFL) emerge as the best classifiers in terms of performance metrics in the identification of SMC. In HbCs, Kernelized pinball general twin support vector machine (Pin-GTSVM-K) excels in CT and WM features, whereas Linear Pin-GTSVM (Pin-GTSVM-L) and Linear intuitionistic fuzzy TSVM (IFTSVM-L) performs well in the JD and GM features sets, respectively. This comprehensive evaluation emphasizes the critical role of feature selection and model choice in attaining an effective classifier for SMC diagnosis. The inclusion of statistical analyses further reinforces the credibility of the results, affirming the rigor of this analysis. The performance measures exhibit the suitability of this framework in aiding researchers with the automated and accurate assessment of SMC. The source codes of the algorithms and datasets used in this study are available at https://github.com/mtanveer1/SMC.

The pitch contours of Mandarin two-character words are generally understood as being shaped by the underlying tones of the constituent single-character words, in interaction with articulatory constraints imposed by factors such as speech rate, co-articulation with adjacent tones, segmental make-up, and predictability. This study shows that tonal realization is also partially determined by words' meanings. We first show, on the basis of a Taiwan corpus of spontaneous conversations, using the generalized additive regression model, and focusing on the rise-fall tone pattern, that after controlling for effects of speaker and context, word type is a stronger predictor of pitch realization than all the previously established word-form related predictors combined. Importantly, the addition of information about meaning in context improves prediction accuracy even further. We then proceed to show, using computational modeling with context-specific word embeddings, that token-specific pitch contours predict word type with 50% accuracy on held-out data, and that context-sensitive, token-specific embeddings can predict the shape of pitch contours with 30% accuracy. These accuracies, which are an order of magnitude above chance level, suggest that the relation between words' pitch contours and their meanings are sufficiently strong to be functional for language users. The theoretical implications of these empirical findings are discussed.

Automatic static cost analysis infers information about the resources used by programs without actually running them with concrete data, and presents such information as functions of input data sizes. Most of the analysis tools for logic programs (and many for other languages), as CiaoPP, are based on setting up recurrence relations representing (bounds on) the computational cost of predicates, and solving them to find closed-form functions. Such recurrence solving is a bottleneck in current tools: many of the recurrences that arise during the analysis cannot be solved with state-of-the-art solvers, including Computer Algebra Systems (CASs), so that specific methods for different classes of recurrences need to be developed. We address such a challenge by developing a novel, general approach for solving arbitrary, constrained recurrence relations, that uses machine-learning (sparse-linear and symbolic) regression techniques to guess a candidate closed-form function, and a combination of an SMT-solver and a CAS to check if it is actually a solution of the recurrence. Our prototype implementation and its experimental evaluation within the context of the CiaoPP system show quite promising results. Overall, for the considered benchmarks, our approach outperforms state-of-the-art cost analyzers and recurrence solvers, and solves recurrences that cannot be solved by them.

Time series prediction is a fundamental problem in scientific exploration and artificial intelligence (AI) technologies have substantially bolstered its efficiency and accuracy. A well-established paradigm in AI-driven time series prediction is injecting physical knowledge into neural networks through signal decomposition methods, and sustaining progress in numerous scenarios has been reported. However, we uncover non-negligible evidence that challenges the effectiveness of signal decomposition in AI-based time series prediction. We confirm that improper dataset processing with subtle future label leakage is unfortunately widely adopted, possibly yielding abnormally superior but misleading results. By processing data in a strictly causal way without any future information, the effectiveness of additional decomposed signals diminishes. Our work probably identifies an ingrained and universal error in time series modeling, and the de facto progress in relevant areas is expected to be revisited and calibrated to prevent future scientific detours and minimize practical losses.

Survival prediction is an important branch of cancer prognosis analysis. The model that predicts survival risk through TCGA genomics data can discover genes related to cancer and provide diagnosis and treatment recommendations based on patient characteristics. We found that deep learning models based on Cox proportional hazards often suffer from overfitting when dealing with high-throughput data. Moreover, we found that as the number of network layers increases, the experimental results will not get better, and network degradation will occur. Based on this problem, we propose a new framework based on Deep Residual Learning. Combine the ideas of Cox proportional hazards and Residual. And name it ResSurv. First, ResSurv is a feed-forward deep learning network stacked by multiple basic ResNet Blocks. In each ResNet Block, we add a Normalization Layer to prevent gradient disappearance and gradient explosion. Secondly, for the loss function of the neural network, we inherited the Cox proportional hazards methods, applied the semi-parametric of the CPH model to the neural network, combined with the partial likelihood model, established the loss function, and performed backpropagation and gradient update. Finally, we compared ResSurv networks of different depths and found that we can effectively extract high-dimensional features. Ablation experiments and comparative experiments prove that our model has reached SOTA(state of the art) in the field of deep learning, and our network can effectively extract deep information.

Self-supervised learning (SSL) has emerged as a promising technique for medical image analysis due to its ability to learn without annotations. However, despite the promising potential, conventional SSL methods encounter limitations, including challenges in achieving semantic alignment and capturing subtle details. This leads to suboptimal representations, which fail to accurately capture the underlying anatomical structures and pathological details. In response to these constraints, we introduce a novel SSL framework OPTiML, employing optimal transport (OT), to capture the dense semantic invariance and fine-grained details, thereby enhancing the overall effectiveness of SSL in medical image representation learning. The core idea is to integrate OT with a cross-viewpoint semantics infusion module (CV-SIM), which effectively captures complex, fine-grained details inherent in medical images across different viewpoints. In addition to the CV-SIM module, OPTiML imposes the variance and covariance regularizations within OT framework to force the model focus on clinically relevant information while discarding less informative features. Through these, the proposed framework demonstrates its capacity to learn semantically rich representations that can be applied to various medical imaging tasks. To validate its effectiveness, we conduct experimental studies on three publicly available datasets from chest X-ray modality. Our empirical results reveal OPTiML's superiority over state-of-the-art methods across all evaluated tasks.

We propose a novel Bayesian approach for the adaptive and online estimation of the frequency distribution of a finite number of categories under the local differential privacy (LDP) framework. The proposed algorithm performs Bayesian parameter estimation via posterior sampling and adapts the randomization mechanism for LDP based on the obtained posterior samples. We propose a randomized mechanism for LDP which uses a subset of categories as an input and whose performance depends on the selected subset and the true frequency distribution. By using the posterior sample as an estimate of the frequency distribution, the algorithm performs a computationally tractable subset selection step to maximize the utility of the privatized response of the next user. We propose several utility functions related to well-known information metrics, such as (but not limited to) Fisher information matrix, total variation distance, and information entropy. We compare each of these utility metrics in terms of their computational complexity. We employ stochastic gradient Langevin dynamics for posterior sampling, a computationally efficient approximate Markov chain Monte Carlo method. We provide a theoretical analysis showing that (i) the posterior distribution targeted by the algorithm converges to the true parameter even for approximate posterior sampling, and (ii) the algorithm selects the optimal subset with high probability if posterior sampling is performed exactly. We also provide numerical results that empirically demonstrate the estimation accuracy of our algorithm where we compare it with nonadaptive and semi-adaptive approaches under experimental settings with various combinations of privacy parameters and population distribution parameters.

Consuming poisonous mushrooms can have severe health consequences, even resulting in fatality and accurately distinguishing edible from toxic mushroom varieties remains a significant challenge in ensuring food safety. So, it's crucial to distinguish between edible and poisonous mushrooms within the existing species. This is essential due to the significant demand for mushrooms in people's daily meals and their potential contributions to medical science. This work presents a novel Quantum Vision Transformer architecture that leverages quantum computing to enhance mushroom classification performance. By implementing specialized quantum self-attention mechanisms using Variational Quantum Circuits, the proposed architecture achieved 92.33% and 99.24% accuracy based on their category and their edibility respectively. This demonstrates the success of the proposed architecture in reducing false negatives for toxic mushrooms, thus ensuring food safety. Our research highlights the potential of QMViT for improving mushroom classification as a whole.

We introduce an Invertible Symbolic Regression (ISR) method. It is a machine learning technique that generates analytical relationships between inputs and outputs of a given dataset via invertible maps (or architectures). The proposed ISR method naturally combines the principles of Invertible Neural Networks (INNs) and Equation Learner (EQL), a neural network-based symbolic architecture for function learning. In particular, we transform the affine coupling blocks of INNs into a symbolic framework, resulting in an end-to-end differentiable symbolic invertible architecture that allows for efficient gradient-based learning. The proposed ISR framework also relies on sparsity promoting regularization, allowing the discovery of concise and interpretable invertible expressions. We show that ISR can serve as a (symbolic) normalizing flow for density estimation tasks. Furthermore, we highlight its practical applicability in solving inverse problems, including a benchmark inverse kinematics problem, and notably, a geoacoustic inversion problem in oceanography aimed at inferring posterior distributions of underlying seabed parameters from acoustic signals.

This paper presents an approach for energy-neutral Internet of Things (IoT) scenarios where the IoT devices (IoTDs) rely entirely on their energy harvesting capabilities to sustain operation. We use a Markov chain to represent the operation and transmission states of the IoTDs, a modulated Poisson process to model their energy harvesting process, and a discrete-time Markov chain to model their battery state. The aim is to efficiently manage the duty cycling of the IoTDs, so as to prolong their battery life and reduce instances of low-energy availability. We propose a duty-cycling management based on K- nearest neighbors, aiming to strike a trade-off between energy efficiency and detection accuracy. This is done by incorporating spatial and temporal correlations among IoTDs' activity, as well as their energy harvesting capabilities. We also allow the base station to wake up specific IoTDs if more information about an event is needed upon initial detection. Our proposed scheme shows significant improvements in energy savings and performance, with up to 11 times lower misdetection probability and 50\% lower energy consumption for high-density scenarios compared to a random duty cycling benchmark.