This study employs a robust analytical framework to uncover patterns in survival outcomes among breast cancer patients from diverse racial and geographical backgrounds. This research uses the SEER 2021 dataset to analyze breast cancer survival outcomes to identify and comprehend dissimilarities. Our approach integrates exploratory data analysis (EDA), through this we identify key variables that influence survival rates and employ survival analysis techniques, including the Kaplan-Meier estimator and log-rank test and the advanced modeling Cox Proportional Hazards model to determine how survival rates vary across racial groups and countries. Model validation and interpretation are undertaken to ensure the reliability of our findings, which are documented comprehensively to inform policymakers and healthcare professionals. The outcome of this paper is a detailed version of statistical analysis that not just highlights disparities in breast cancer treatment and care but also serves as a foundational tool for developing targeted interventions to address the inequalities effectively. Through this research, our aim is to contribute to the global efforts to improve breast cancer outcomes and reduce treatment disparities.

Traffic prediction is a critical task in spatial-temporal forecasting with broad applications in travel planning and urban management. Adaptive graph convolution networks have emerged as mainstream solutions due to their ability to learn node embeddings in a data-driven manner and capture complex latent dependencies. However, existing adaptive graph learning methods for traffic forecasting often either ignore the regularization of node embeddings, which account for a significant proportion of model parameters, or face scalability issues from expensive graph convolution operations. To address these challenges, we propose a Regularized Adaptive Graph Learning (RAGL) model. First, we introduce a regularized adaptive graph learning framework that synergizes Stochastic Shared Embedding (SSE) and adaptive graph convolution via a residual difference mechanism, achieving both embedding regularization and noise suppression. Second, to ensure scalability on large road networks, we develop the Efficient Cosine Operator (ECO), which performs graph convolution based on the cosine similarity of regularized embeddings with linear time complexity. Extensive experiments on four large-scale real-world traffic datasets show that RAGL consistently outperforms state-of-the-art methods in terms of prediction accuracy and exhibits competitive computational efficiency.

In the realm of Text-attributed Graphs (TAGs), traditional graph neural networks (GNNs) often fall short due to the complex textual information associated with each node. Recent methods have improved node representations by leveraging large language models (LLMs) to enhance node text features, but these approaches typically require extensive annotations or fine-tuning across all nodes, which is both time-consuming and costly. To overcome these challenges, we introduce GAGA, an efficient framework for TAG representation learning. GAGA reduces annotation time and cost by focusing on annotating only representative nodes and edges. It constructs an annotation graph that captures the topological relationships among these annotations. Furthermore, GAGA employs a two-level alignment module to effectively integrate the annotation graph with the TAG, aligning their underlying structures. Experiments show that GAGA achieves classification accuracies on par with or surpassing state-of-the-art methods while requiring only 1% of the data to be annotated, demonstrating its high efficiency.

--Personalized Federated Learning (PFL) enables clients to collaboratively train personalized models tailored to their individual objectives, addressing the challenge of model generalization in traditional Federated Learning (FL) due to high data heterogeneity. However, existing PFL methods often require increased communication rounds to achieve the desired performance, primarily due to slow training caused by the use of first-order optimization, which has linear convergence. Additionally, many of these methods increase local computation because of the additional data fed into the model during the search for personalized local models. One promising solution to this slow training is second-order optimization, known for its quadratic convergence. However, employing it in PFL is challenging due to the Hessian matrix and its inverse. In this paper, we propose pFedSOP, which efficiently utilizes second-order optimization in PFL to accelerate the training of personalized models and enhance performance with fewer communication rounds. Our approach first computes a personalized local gradient update using the Gompertz function-based normalized angle between local and global gradient updates, incorporating client-specific global information. We then use a regularized Fisher Information Matrix (FIM), computed from this personalized gradient update, as an approximation of the Hessian to update the personalized models. This FIM-based second-order optimization speeds up training with fewer communication rounds by tackling the challenges with exact Hessian and avoids additional data being fed into the model during the search for personalized local models. Extensive experiments on heterogeneously partitioned image classification datasets with partial client participation demonstrate that pFedSOP outperforms state-of-the-art FL and PFL algorithms.

Missing data in spatiotemporal systems presents a significant challenge for modern applications, ranging from environmental monitoring to urban traffic management. The integrity of spatiotemporal data often deteriorates due to hardware malfunctions and software failures in real-world deployments. Current approaches based on machine learning and deep learning struggle to model the intricate interdependencies between spatial and temporal dimensions effectively and, more importantly, suffer from cumulative errors during the data imputation process, which propagate and amplify through iterations. To address these limitations, we propose CoFILL, a novel Conditional Diffusion Model for spatiotemporal data imputation. CoFILL builds on the inherent advantages of diffusion models to generate high-quality imputations without relying on potentially error-prone prior estimates. It incorporates an innovative dual-stream architecture that processes temporal and frequency domain features in parallel. By fusing these complementary features, CoFILL captures both rapid fluctuations and underlying patterns in the data, which enables more robust imputation. The extensive experiments reveal that CoFILL's noise prediction network successfully transforms random noise into meaningful values that align with the true data distribution. The results also show that CoFILL outperforms state-of-the-art methods in imputation accuracy. The source code is publicly available at https://github.com/joyHJL/CoFILL.

Patient similarity computation (PSC) is a fundamental problem in healthcare informatics. The aim of the patient similarity computation is to measure the similarity among patients according to their historical clinical records, which helps to improve clinical decision support. This paper presents a novel distributed patient similarity computation (DPSC) technique based on data transformation (DT) methods, utilizing an effective combination of time series and static data. Time series data are sensor-collected patients' information, including metrics like heart rate, blood pressure, Oxygen saturation, respiration, etc. The static data are mainly patient background and demographic data, including age, weight, height, gender, etc. Static data has been used for clustering the patients. Before feeding the static data to the machine learning model adaptive Weight-of-Evidence (aWOE) and Z-score data transformation (DT) methods have been performed, which improve the prediction performances. In aWOE-based patient similarity models, sensitive patient information has been processed using aWOE which preserves the data privacy of the trained models. We used the Dynamic Time Warping (DTW) approach, which is robust and very popular, for time series similarity. However, DTW is not suitable for big data due to the significant computational run-time. To overcome this problem, distributed DTW computation is used in this study. For Coronary Artery Disease, our DT based approach boosts prediction performance by as much as 11.4%, 10.20%, and 12.6% in terms of AUC, accuracy, and F-measure, respectively. In the case of Congestive Heart Failure (CHF), our proposed method achieves performance enhancement up to 15.9%, 10.5%, and 21.9% for the same measures, respectively. The proposed method reduces the computation time by as high as 40%.

Differential Privacy (DP) is a widely adopted technique, valued for its effectiveness in protecting the privacy of task-specific datasets, making it a critical tool for large language models. However, its effectiveness in Multimodal Large Language Models (MLLMs) remains uncertain. Applying Differential Privacy (DP) inherently introduces substantial computation overhead, a concern particularly relevant for MLLMs which process extensive textual and visual data. Furthermore, a critical challenge of DP is that the injected noise, necessary for privacy, scales with parameter dimensionality, leading to pronounced model degradation; This trade-off between privacy and utility complicates the application of Differential Privacy (DP) to complex architectures like MLLMs. To address these, we propose Dual-Priv Pruning, a framework that employs two complementary pruning mechanisms for DP fine-tuning in MLLMs: (i) visual token pruning to reduce input dimensionality by removing redundant visual information, and (ii) gradient-update pruning during the DP optimization process. This second mechanism selectively prunes parameter updates based on the magnitude of noisy gradients, aiming to mitigate noise impact and improve utility. Experiments demonstrate that our approach achieves competitive results with minimal performance degradation. In terms of computational efficiency, our approach consistently utilizes less memory than standard DP-SGD. While requiring only 1.74% more memory than zeroth-order methods which suffer from severe performance issues on A100 GPUs, our method demonstrates leading memory efficiency on H20 GPUs. To the best of our knowledge, we are the first to explore DP fine-tuning in MLLMs. Our code is coming soon.

Natural intelligence (NI) consistently achieves more with less. Infants learn language, develop abstract concepts, and acquire sensorimotor skills from sparse data, all within tight neural and energy limits. In contrast, today's AI relies on virtually unlimited computational power, energy, and data to reach high performance. This paper argues that constraints in NI are paradoxically catalysts for efficiency, adaptability, and creativity. We first show how limited neural bandwidth promotes concise codes that still capture complex patterns. Spiking neurons, hierarchical structures, and symbolic-like representations emerge naturally from bandwidth constraints, enabling robust generalization. Next, we discuss chaotic itinerancy, illustrating how the brain transits among transient attractors to flexibly retrieve memories and manage uncertainty. We then highlight reservoir computing, where random projections facilitate rapid generalization from small datasets. Drawing on developmental perspectives, we emphasize how intrinsic motivation, along with responsive social environments, drives infant language learning and discovery of meaning. Such active, embodied processes are largely absent in current AI. Finally, we suggest that adopting 'less is more' principles -- energy constraints, parsimonious architectures, and real-world interaction -- can foster the emergence of more efficient, interpretable, and biologically grounded artificial systems.

Machine learning (ML) systems are utilized in critical sectors, such as healthcare, law enforcement, and finance. However, these systems are often trained on historical data that contains demographic biases, leading to ML decisions that perpetuate or exacerbate existing social inequalities. Causal fairness provides a transparent, human-in-the-loop framework to mitigate algorithmic discrimination, aligning closely with legal doctrines of direct and indirect discrimination. However, current causal fairness frameworks hold a key limitation in that they assume prior knowledge of the correct causal model, restricting their applicability in complex fairness scenarios where causal models are unknown or difficult to identify. To bridge this gap, we propose FairPFN, a tabular foundation model pre-trained on synthetic causal fairness data to identify and mitigate the causal effects of protected attributes in its predictions. FairPFN's key contribution is that it requires no knowledge of the causal model and still demonstrates strong performance in identifying and removing protected causal effects across a diverse set of hand-crafted and real-world scenarios relative to robust baseline methods. FairPFN paves the way for promising future research, making causal fairness more accessible to a wider variety of complex fairness problems.

Driver drowsiness detection (DDD) prevents road accidents caused by driver fatigue. Vehicle dynamics-based DDD has been proposed as a method that is both economical and high performance. However, there are concerns about the reliability of performance metrics and the reproducibility of many of the existing methods. For instance, some previous studies seem to have a data leakage issue among training and test datasets, and many do not openly provide the datasets they used. To this end, this paper aims to compare the performance of representative vehicle dynamics-based DDD methods under a transparent and fair framework that uses a public dataset. We first develop a framework for extracting features from an open dataset by Aygun et al. and performing DDD with lightweight ML models; the framework is carefully designed to support a variety of onfigurations. Second, we implement three existing representative methods and a concise random forest (RF)-based method in the framework. Finally, we report the results of experiments to verify the reproducibility and clarify the performance of DDD based on common metrics. Among the evaluated methods, the RF-based method achieved the highest accuracy of 88 %. Our findings imply the issues inherent in DDD methods developed in a non-standard manner, and demonstrate a high performance method implemented appropriately.