Statistical Learning
Machine Understanding of Scientific Language
Scientific information expresses human understanding of nature. This knowledge is largely disseminated in different forms of text, including scientific papers, news articles, and discourse among people on social media. While important for accelerating our pursuit of knowledge, not all scientific text is faithful to the underlying science. As the volume of this text has burgeoned online in recent years, it has become a problem of societal importance to be able to identify the faithfulness of a given piece of scientific text automatically. This thesis is concerned with the cultivation of datasets, methods, and tools for machine understanding of scientific language, in order to analyze and understand science communication at scale. To arrive at this, I present several contributions in three areas of natural language processing and machine learning: automatic fact checking, learning with limited data, and scientific text processing. These contributions include new methods and resources for identifying check-worthy claims, adversarial claim generation, multi-source domain adaptation, learning from crowd-sourced labels, cite-worthiness detection, zero-shot scientific fact checking, detecting exaggerated scientific claims, and modeling degrees of information change in science communication. Critically, I demonstrate how the research outputs of this thesis are useful for effectively learning from limited amounts of scientific text in order to identify misinformative scientific statements and generate new insights into the science communication process
Differentially Private Synthetic Data Release for Topics API Outputs
Dick, Travis, Epasto, Alessandro, Javanmard, Adel, Karlin, Josh, Medina, Andres Munoz, Mirrokni, Vahab, Vassilvitskii, Sergei, Zhong, Peilin
The analysis of the privacy properties of Privacy-Preserving Ads APIs is an area of research that has received strong interest from academics, industry, and regulators. Despite this interest, the empirical study of these methods is hindered by the lack of publicly available data. Reliable empirical analysis of the privacy properties of an API, in fact, requires access to a dataset consisting of realistic API outputs; however, privacy concerns prevent the general release of such data to the public. In this work, we develop a novel methodology to construct synthetic API outputs that are simultaneously realistic enough to enable accurate study and provide strong privacy protections. We focus on one Privacy-Preserving Ads APIs: the Topics API, part of Google Chrome's Privacy Sandbox. We developed a methodology to generate a differentially-private dataset that closely matches the re-identification risk properties of the real Topics API data. The use of differential privacy provides strong theoretical bounds on the leakage of private user information from this release. Our methodology is based on first computing a large number of differentially-private statistics describing how output API traces evolve over time. Then, we design a parameterized distribution over sequences of API traces and optimize its parameters so that they closely match the statistics obtained. Finally, we create the synthetic data by drawing from this distribution. Our work is complemented by an open-source release of the anonymized dataset obtained by this methodology. We hope this will enable external researchers to analyze the API in-depth and replicate prior and future work on a realistic large-scale dataset. We believe that this work will contribute to fostering transparency regarding the privacy properties of Privacy-Preserving Ads APIs.
Geminet: Learning the Duality-based Iterative Process for Lightweight Traffic Engineering in Changing Topologies
Liu, Ximeng, Zhao, Shizhen, Wang, Xinbing
Recently, researchers have explored ML-based Traffic Engineering (TE), leveraging neural networks to solve TE problems traditionally addressed by optimization. However, existing ML-based TE schemes remain impractical: they either fail to handle topology changes or suffer from poor scalability due to excessive computational and memory overhead. To overcome these limitations, we propose Geminet, a lightweight and scalable ML-based TE framework that can handle changing topologies. Geminet is built upon two key insights: (i) a methodology that decouples neural networks from topology by learning an iterative gradient-descent-based adjustment process, as the update rule of gradient descent is topology-agnostic, relying only on a few gradient-related quantities; (ii) shifting optimization from path-level routing weights to edge-level dual variables, reducing memory consumption by leveraging the fact that edges are far fewer than paths. Evaluations on WAN and data center datasets show that Geminet significantly improves scalability. Its neural network size is only 0.04% to 7% of existing schemes, while handling topology variations as effectively as HARP, a state-of-the-art ML-based TE approach, without performance degradation. When trained on large-scale topologies, Geminet consumes under 10 GiB of memory, more than eight times less than the 80-plus GiB required by HARP, while achieving 5.45 times faster convergence speed, demonstrating its potential for large-scale deployment.
CSBrain: A Cross-scale Spatiotemporal Brain Foundation Model for EEG Decoding
Zhou, Yuchen, Wu, Jiamin, Ren, Zichen, Yao, Zhouheng, Lu, Weiheng, Peng, Kunyu, Zheng, Qihao, Song, Chunfeng, Ouyang, Wanli, Gou, Chao
Understanding and decoding brain activity from electroencephalography (EEG) signals is a fundamental challenge in neuroscience and AI, with applications in cognition, emotion recognition, diagnosis, and brain-computer interfaces. While recent EEG foundation models advance generalized decoding via unified architectures and large-scale pretraining, they adopt a scale-agnostic dense modeling paradigm inherited from NLP and vision. This design neglects a core property of neural activity: cross-scale spatiotemporal structure. EEG task patterns span a wide range of temporal and spatial scales, from short bursts to slow rhythms, and from localized cortical responses to distributed interactions. Ignoring this diversity leads to suboptimal representations and weak generalization. We propose CSBrain, a Cross-scale Spatiotemporal Brain foundation model for generalized EEG decoding. CSBrain introduces: (i) Cross-scale Spatiotemporal Tokenization (CST), which aggregates multi-scale features from localized temporal windows and anatomical brain regions into compact scale-aware tokens; and (ii) Structured Sparse Attention (SSA), which captures cross-window and cross-region dependencies, enhancing scale diversity while removing spurious correlations. CST and SSA are alternately stacked to progressively integrate multi-scale dependencies. Experiments on 11 EEG tasks across 16 datasets show that CSBrain consistently outperforms task-specific and foundation model baselines. These results establish cross-scale modeling as a key inductive bias and position CSBrain as a robust backbone for future brain-AI research.
Hindsight-Guided Momentum (HGM) Optimizer: An Approach to Adaptive Learning Rate
We introduce Hindsight-Guided Momentum (HGM), a first-order optimization algorithm that adaptively scales learning rates based on the directional consistency of recent updates. Traditional adaptive methods, such as Adam or RMSprop , adapt learning dynamics using only the magnitude of gradients, often overlooking important geometric cues.Geometric cues refer to directional information, such as the alignment between current gradients and past updates, which reflects the local curvature and consistency of the optimization path. HGM addresses this by incorporating a hindsight mechanism that evaluates the cosine similarity between the current gradient and accumulated momentum. This allows it to distinguish between coherent and conflicting gradient directions, increasing the learning rate when updates align and reducing it in regions of oscillation or noise. The result is a more responsive optimizer that accelerates convergence in smooth regions of the loss surface while maintaining stability in sharper or more erratic areas. Despite this added adaptability, the method preserves the computational and memory efficiency of existing optimizers.By more intelligently responding to the structure of the optimization landscape, HGM provides a simple yet effective improvement over existing approaches, particularly in non-convex settings like that of deep neural network training.
Unsupervised Discovery of Behavioral Primitives from Sensorimotor Dynamic Functional Connectivity
Ledezma, Fernando Diaz, Marcel, Valentin, Hoffmann, Matej
Abstract-- The movements of both animals and robots give rise to streams of high-dimensional motor and sensory information. Imagine the brain of a newborn or the controller of a baby humanoid robot trying to make sense of unprocessed sensorimotor time series. Here, we present a framework for studying the dynamic functional connectivity between the multimodal sensory signals of a robotic agent to uncover an underlying structure. Using instantaneous mutual information, we capture the time-varying functional connectivity (FC) between proprioceptive, tactile, and visual signals, revealing the sensorimotor relationships. Using an infinite relational model, we identified sensorimotor modules and their evolving connectivity. To further interpret these dynamic interactions, we employed non-negative matrix factorization, which decomposed the connectivity patterns into additive factors and their corresponding temporal coefficients. These factors can be considered the agent's motion primitives or movement synergies that the agent can use to make sense of its sensorimotor space and later for behavior selection. In the future, the method can be deployed in robot learning as well as in the analysis of human movement trajectories or brain signals.
Microelectrode Signal Dynamics as Biomarkers of Subthalamic Nucleus Entry on Deep Brain Stimulation: A Nonlinear Feature Approach
Tavares, Ana Luiza S., Neto, Artur Pedro M., Gomes, Francinaldo L., Reis, Paul Rodrigo dos, da Silva, Arthur G., Junior, Antonio P., Gomes, Bruno D.
Accurate intraoperative localization of the subthalamic nucleus (STN) is essential for the efficacy of Deep Brain Stimulation (DBS) in patients with Parkinson's disease. While microelectrode recordings (MERs) provide rich electrophysiological information during DBS electrode implantation, current localization practices often rely on subjective interpretation of signal features. In this study, we propose a quantitative framework that leverages nonlinear dynamics and entropy-based metrics to classify neural activity recorded inside versus outside the STN. MER data from three patients were preprocessed using a robust artifact correction pipeline, segmented, and labelled based on surgical annotations. A comprehensive set of recurrence quantification analysis, nonlinear, and entropy features were extracted from each segment. Multiple supervised classifiers were trained on every combination of feature domains using stratified 10-fold cross-validation, followed by statistical comparison using paired Wilcoxon signed-rank tests with Holm-Bonferroni correction. The combination of entropy and nonlinear features yielded the highest discriminative power, and the Extra Trees classifier emerged as the best model with a cross-validated F1-score of 0.902+/-0.027 and ROC AUC of 0.887+/-0.055. Final evaluation on a 20% hold-out test set confirmed robust generalization (F1= 0.922, ROC AUC = 0.941). These results highlight the potential of nonlinear and entropy signal descriptors in supporting real-time, data-driven decision-making during DBS surgeries
Latent Factorization of Tensors with Threshold Distance Weighted Loss for Traffic Data Estimation
Intelligent transportation systems (ITS) rely heavily on comp lete and high - quality spatiotemporal traffic data to achieve optimal performance. Nevertheless, in real - word traffic data collection processes, issues such as communication failures and sensor malfunctions often lead to incomplete or corrupted datasets, th ereby posing significant challenges to the advancement of ITS. Among various methods for imputing missing spatiotemporal traffic data, the latent factorization of tensors (LFT) model has emerged as a widely adopted and effective solution. However, conventi onal LFT models typically employ the standard L 2 - norm in their learning objective, which makes them vulnerable to the influence of outliers. To overcome this limitation, this paper proposes a threshold distance weighted (TDW) loss - incorporated Latent Facto ri zation of Tensors ( TDW LFT) model . The proposed loss function effectively reduces the model's sensitivity to outliers by assigning differentiated weights to individual samples. Extensive experiments conducted on two traffic speed datasets sourced from div erse urban environments confirm that the proposed TDW LFT model consistently outperforms state - of - the - art approaches in terms of both in both prediction accuracy and computational efficiency .
Automatic Depression Assessment using Machine Learning: A Comprehensive Survey
Song, Siyang, Huo, Yupeng, Tang, Shiqing, Cheong, Jiaee, Gao, Rui, Valstar, Michel, Gunes, Hatice
Depression is a common mental illness across current human society. Traditional depression assessment relying on inventories and interviews with psychologists frequently suffer from subjective diagnosis results, slow and expensive diagnosis process as well as lack of human resources. Since there is a solid evidence that depression is reflected by various human internal brain activities and external expressive behaviours, early traditional machine learning (ML) and advanced deep learning (DL) models have been widely explored for human behaviour-based automatic depression assessment (ADA) since 2012. However, recent ADA surveys typically only focus on a limited number of human behaviour modalities. Despite being used as a theoretical basis for developing ADA approaches, existing ADA surveys lack a comprehensive review and summary of multi-modal depression-related human behaviours. To bridge this gap, this paper specifically summarises depression-related human behaviours across a range of modalities (e.g. the human brain, verbal language and non-verbal audio/facial/body behaviours). We focus on conducting an up-to-date and comprehensive survey of ML-based ADA approaches for learning depression cues from these behaviours as well as discussing and comparing their distinctive features and limitations. In addition, we also review existing ADA competitions and datasets, identify and discuss the main challenges and opportunities to provide further research directions for future ADA researchers.
Aligning Evaluation with Clinical Priorities: Calibration, Label Shift, and Error Costs
Flores, Gerardo A., Smith, Alyssa H., Fukuyama, Julia A., Wilson, Ashia C.
Machine learning-based decision support systems are increasingly deployed in clinical settings, where probabilistic scoring functions are used to inform and prioritize patient management decisions. However, widely used scoring rules, such as accuracy and AUC-ROC, fail to adequately reflect key clinical priorities, including calibration, robustness to distributional shifts, and sensitivity to asymmetric error costs. In this work, we propose a principled yet practical evaluation framework for selecting calibrated thresholded classifiers that explicitly accounts for the uncertainty in class prevalences and domain-specific cost asymmetries often found in clinical settings. Building on the theory of proper scoring rules, particularly the Schervish representation, we derive an adjusted variant of cross-entropy (log score) that averages cost-weighted performance over clinically relevant ranges of class balance. The resulting evaluation is simple to apply, sensitive to clinical deployment conditions, and designed to prioritize models that are both calibrated and robust to real-world variations.