Although the amount of available spoken content is steadily increasing, extracting information and knowledge from speech recordings remains challenging. Beyond enhancing traditional information retrieval methods such as speech search and keyword spotting, novel approaches for navigating and searching spoken content need to be explored and developed. In this paper, we propose a novel navigational method for speech archives that leverages recent advances in language and multimodal generative models. We demonstrate our approach with a Web application that organizes data into a structured format using interactive mind maps and image generation tools. The system is implemented using the TED-LIUM~3 dataset, which comprises over 2,000 speech transcripts and audio files of TED Talks. Initial user tests using a System Usability Scale (SUS) questionnaire indicate the application's potential to simplify the exploration of large speech collections.

Action-driven stochastic human motion prediction aims to generate future motion sequences of a pre-defined target action based on given past observed sequences performing non-target actions. This task primarily presents two challenges. Firstly, generating smooth transition motions is hard due to the varying transition speeds of different actions. Secondly, the action characteristic is difficult to be learned because of the similarity of some actions. These issues cause the predicted results to be unreasonable and inconsistent. As a result, we propose two memory banks, the Soft-transition Action Bank (STAB) and Action Characteristic Bank (ACB), to tackle the problems above. The STAB stores the action transition information. It is equipped with the novel soft searching approach, which encourages the model to focus on multiple possible action categories of observed motions. The ACB records action characteristic, which produces more prior information for predicting certain actions. To fuse the features retrieved from the two banks better, we further propose the Adaptive Attention Adjustment (AAA) strategy. Extensive experiments on four motion prediction datasets demonstrate that our approach consistently outperforms the previous state-of-the-art. The demo and code are available at https://hyqlat.github.io/STABACB.github.io/.

Multimodal representation is faithful and highly effective in describing real-world data samples' characteristics by describing their complementary information. However, the collected data often exhibits incomplete and misaligned characteristics due to factors such as inconsistent sensor frequencies and device malfunctions. Existing research has not effectively addressed the issue of filling missing data in scenarios where multiview data are both imbalanced and misaligned. Instead, it relies on class-level alignment of the available data. Thus, it results in some data samples not being well-matched, thereby affecting the quality of data fusion. In this paper, we propose the Consistency-A ware Padding for Incomplete Multimodal Alignment Clustering Based on Self-Repellent Greedy Anchor Search(CAPIMAC) to tackle the problem of filling imbalanced and mis-aligned data in multimodal datasets. Specifically, we propose a self-repellent greedy anchor search module(SRGASM), which employs a self-repellent random walk combined with a greedy algorithm to identify anchor points for re-representing incomplete and misaligned multimodal data. Subsequently, based on noise-contrastive learning, we design a consistency-aware padding module (CAPM) to effectively interpolate and align imbalanced and misaligned data, thereby improving the quality of multimodal data fusion. Experimental results demonstrate the superiority of our method over benchmark datasets.

Feature interaction modeling is crucial for deep recommendation models. A common and effective approach is to construct explicit feature combinations to enhance model performance. However, in practice, only a small fraction of these combinations are truly informative. Thus it is essential to select useful feature combinations to reduce noise and manage memory consumption. While feature selection methods have been extensively studied, they are typically limited to selecting individual features. Extending these methods for high-order feature combination selection presents a significant challenge due to the exponential growth in time complexity when evaluating feature combinations one by one. In this paper, we propose $\textbf{TayFCS}$, a lightweight feature combination selection method that significantly improves model performance. Specifically, we propose the Taylor Expansion Scorer (TayScorer) module for field-wise Taylor expansion on the base model. Instead of evaluating all potential feature combinations' importance by repeatedly running experiments with feature adding and removal, this scorer only needs to approximate the importance based on their sub-components' gradients. This can be simply computed with one backward pass based on a trained recommendation model. To further reduce information redundancy among feature combinations and their sub-components, we introduce Logistic Regression Elimination (LRE), which estimates the corresponding information gain based on the model prediction performance. Experimental results on three benchmark datasets validate both the effectiveness and efficiency of our approach. Furthermore, online A/B test results demonstrate its practical applicability and commercial value.

This paper systematically reviews recent advances in artificial intelligence (AI), with a particular focus on machine learning (ML), across the entire drug discovery pipeline. Due to the inherent complexity, escalating costs, prolonged timelines, and high failure rates of traditional drug discovery methods, there is a critical need to comprehensively understand how AI/ML can be effectively integrated throughout the full process. Currently available literature reviews often narrowly focus on specific phases or methodologies, neglecting the dependence between key stages such as target identification, hit screening, and lead optimization. To bridge this gap, our review provides a detailed and holistic analysis of AI/ML applications across these core phases, highlighting significant methodological advances and their impacts at each stage. We further illustrate the practical impact of these techniques through an in-depth case study focused on hyperuricemia, gout arthritis, and hyperuricemic nephropathy, highlighting real-world successes in molecular target identification and therapeutic candidate discovery. Additionally, we discuss significant challenges facing AI/ML in drug discovery and outline promising future research directions. Ultimately, this review serves as an essential orientation for researchers aiming to leverage AI/ML to overcome existing bottlenecks and accelerate drug discovery.

Domain adaptation has become a widely adopted approach in machine learning due to the high costs associated with labeling data. It is typically applied when access to a labeled source domain is available. However, in real-world scenarios, privacy concerns often restrict access to sensitive information, such as fingerprints, bank account details, and facial images. A promising solution to this issue is Source-Free Unsupervised Domain Adaptation (SFUDA), which enables domain adaptation without requiring access to labeled target domain data. Recent research demonstrates that SFUDA can effectively address domain discrepancies; however, two key challenges remain: (1) the low quality of prototype samples, and (2) the incorrect assignment of pseudo-labels. To tackle these challenges, we propose a method consisting of three main phases. In the first phase, we introduce a Reliable Sample Memory (RSM) module to improve the quality of prototypes by selecting more representative samples. In the second phase, we employ a Multi-View Contrastive Learning (MVCL) approach to enhance pseudo-label quality by leveraging multiple data augmentations. In the final phase, we apply a noisy label filtering technique to further refine the pseudo-labels. Our experiments on three benchmark datasets - VisDA 2017, Office-Home, and Office-31 - demonstrate that our method achieves approximately 2 percent and 6 percent improvements in classification accuracy over the second-best method and the average of 13 well-known state-of-the-art approaches, respectively.

Despite the impressive advancements in modern machine learning, achieving robustness in Domain Generalization (DG) tasks remains a significant challenge. In DG, models are expected to perform well on samples from unseen test distributions (also called domains), by learning from multiple related training distributions. Most existing approaches to this problem rely on single-valued predictions, which inherently limit their robustness. We argue that set-valued predictors could be leveraged to enhance robustness across unseen domains, while also taking into account that these sets should be as small as possible. We introduce a theoretical framework defining successful set prediction in the DG setting, focusing on meeting a predefined performance criterion across as many domains as possible, and provide theoretical insights into the conditions under which such domain generalization is achievable. We further propose a practical optimization method compatible with modern learning architectures, that balances robust performance on unseen domains with small prediction set sizes. We evaluate our approach on several real-world datasets from the WILDS benchmark, demonstrating its potential as a promising direction for robust domain generalization.

This study investigates the feasibility and performance of federated learning (FL) for multi-label ICD code classification using clinical notes from the MIMIC-IV dataset. Unlike previous approaches that rely on centralized training or fine-tuned large language models, we propose a lightweight and scalable pipeline combining frozen text embeddings with simple multilayer perceptron (MLP) classifiers. This design offers a privacy-preserving and deployment-efficient alternative for clinical NLP applications, particularly suited to distributed healthcare settings. Extensive experiments across both centralized and federated configurations were conducted, testing six publicly available embedding models from Massive Text Embedding Benchmark leaderboard and three MLP classifier architectures under two medical coding (ICD-9 and ICD-10). Additionally, ablation studies over ten random stratified splits assess performance stability. Results show that embedding quality substantially outweighs classifier complexity in determining predictive performance, and that federated learning can closely match centralized results in idealized conditions. While the models are orders of magnitude smaller than state-of-the-art architectures and achieved competitive micro and macro F1 scores, limitations remain including the lack of end-to-end training and the simplified FL assumptions. Nevertheless, this work demonstrates a viable way toward scalable, privacy-conscious medical coding systems and offers a step toward for future research into federated, domain-adaptive clinical AI.

--Privacy-preserving distributed model training is crucial for modern machine learning applications, yet existing Federated Learning approaches struggle with heterogeneous data distributions and varying computational capabilities. Traditional solutions either treat all participants uniformly or require costly dynamic clustering during training, leading to reduced efficiency and delayed model specialization. We present FedCCL (Federated Clustered Continual Learning), a framework specifically designed for environments with static organizational characteristics but dynamic client availability. By combining static pre-training clustering with an adapted asynchronous FedA vg algorithm, Fed-CCL enables new clients to immediately profit from specialized models without prior exposure to their data distribution, while maintaining reduced coordination overhead and resilience to client disconnections. Our approach implements an asynchronous Federated Learning protocol with a three-tier model topology -- global, cluster-specific, and local models -- that efficiently manages knowledge sharing across heterogeneous participants. Evaluation using photovoltaic installations across central Europe demonstrates that FedCCL's location-based clustering achieves an energy prediction error of 3.93% ( 0.21%), while maintaining data privacy and showing that the framework maintains stability for population-independent deployments, with 0.14 percentage point degradation in performance for new installations. The results demonstrate that FedCCL offers an effective framework for privacy-preserving distributed learning, maintaining high accuracy and adaptability even with dynamic participant populations. The Federated Learning (FL) paradigm [1], [2] has emerged as a pivotal solution for privacy-preserving machine learning, enabling multiple participants to collaboratively train models while maintaining data privacy.

The emergence of Open Banking represents a significant shift in financial data management, influencing financial institutions' market dynamics and marketing strategies. This increased competition creates opportunities and challenges, as institutions manage data inflow to improve products and services while mitigating data outflow that could aid competitors. This study introduces a framework to predict customers' propensity to share data via Open Banking and interprets this behavior through Explanatory Model Analysis (EMA). Using data from a large Brazilian financial institution with approximately 3.2 million customers, a hybrid data balancing strategy incorporating ADASYN and NEARMISS techniques was employed to address the infrequency of data sharing and enhance the training of XGBoost models. These models accurately predicted customer data sharing, achieving 91.39% accuracy for inflow and 91.53% for outflow. The EMA phase combined the Shapley Additive Explanations (SHAP) method with the Classification and Regression Tree (CART) technique, revealing the most influential features on customer decisions. Key features included the number of transactions and purchases in mobile channels, interactions within these channels, and credit-related features, particularly credit card usage across the national banking system. These results highlight the critical role of mobile engagement and credit in driving customer data-sharing behaviors, providing financial institutions with strategic insights to enhance competitiveness and innovation in the Open Banking environment.