Transformers are the de-facto choice for sequence modelling, yet their quadratic self-attention and weak temporal bias can make long-range forecasting both expensive and brittle. We introduce FreezeTST, a lightweight hybrid that interleaves frozen random-feature (reservoir) blocks with standard trainable Transformer layers. The frozen blocks endow the network with rich nonlinear memory at no optimisation cost; the trainable layers learn to query this memory through self-attention. The design cuts trainable parameters and also lowers wall-clock training time, while leaving inference complexity unchanged. On seven standard long-term forecasting benchmarks, FreezeTST consistently matches or surpasses specialised variants such as Informer, Autoformer, and PatchTST; with substantially lower compute. Our results show that embedding reservoir principles within Transformers offers a simple, principled route to efficient long-term time-series prediction.

A driver's health state serves as a determinant factor in driving behavioral regulation. Subtle deviations from normalcy can lead to operational anomalies, posing risks to public transportation safety. While prior efforts have developed detection mechanisms for functionally-driven temporary anomalies such as drowsiness and distraction, limited research has addressed pathologically-triggered deviations, especially those stemming from chronic medical conditions. To bridge this gap, we investigate the driving behavior of Parkinson's disease patients and propose SAFE-D, a novel framework for detecting Parkinson-related behavioral anomalies to enhance driving safety. Our methodology starts by performing analysis of Parkinson's disease symptomatology, focusing on primary motor impairments, and establishes causal links to degraded driving performance. To represent the subclinical behavioral variations of early-stage Parkinson's disease, our framework integrates data from multiple vehicle control components to build a behavioral profile. We then design an attention-based network that adaptively prioritizes spatiotemporal features, enabling robust anomaly detection under physiological variability. Finally, we validate SAFE-D on the Logitech G29 platform and CARLA simulator, using data from three road maps to emulate real-world driving. Our results show SAFE-D achieves 96.8% average accuracy in distinguishing normal and Parkinson-affected driving patterns.

The advent of large-scale artificial intelligence (AI) models has a transformative effect on neuroscience research, which represents a paradigm shift from the traditional computational methods through the facilitation of end-to-end learning from raw brain signals and neural data. In this paper, we explore the transformative effects of large-scale AI models on five major neuroscience domains: neuroimaging and data processing, brain-computer interfaces and neural decoding, molecular neuroscience and genomic modeling, clinical assistance and translational frameworks, and disease-specific applications across neurological and psychiatric disorders. These models are demonstrated to address major computational neuroscience challenges, including multimodal neural data integration, spatiotemporal pattern interpretation, and the derivation of translational frameworks for clinical deployment. Moreover, the interaction between neuroscience and AI has become increasingly reciprocal, as biologically informed architectural constraints are now incorporated to develop more interpretable and computationally efficient models. This review highlights both the notable promise of such technologies and key implementation considerations, with particular emphasis on rigorous evaluation frameworks, effective domain knowledge integration, and comprehensive ethical guidelines for clinical use. Finally, a systematic listing of critical neuroscience datasets used to derive and validate large-scale AI models across diverse research applications is provided.

Timely and reliable decision-making is vital for flood emergency response, yet it remains severely hindered by limited and imprecise situational awareness due to various budget and data accessibility constraints. Traditional flood management systems often rely on in-situ sensors to calibrate remote sensing-based large-scale flood depth forecasting models, and further take flood depth estimates to optimize flood response decisions. However, these approaches often take fixed, decision task-agnostic strategies to decide where to put in-situ sensors (e.g., maximize overall information gain) and train flood forecasting models (e.g., minimize average forecasting errors), but overlook that systems with the same sensing gain and average forecasting errors may lead to distinct decisions. To address this, we introduce a novel decision-focused framework that strategically selects locations for in-situ sensor placement and optimize spatio-temporal flood forecasting models to optimize downstream flood response decision regrets. Our end-to-end pipeline integrates four components: a contextual scoring network, a differentiable sensor selection module under hard budget constraints, a spatio-temporal flood reconstruction and forecasting model, and a differentiable decision layer tailored to task-specific objectives. Central to our approach is the incorporation of Implicit Maximum Likelihood Estimation (I-MLE) to enable gradient-based learning over discrete sensor configurations, and probabilistic decision heads to enable differentiable approximation to various constrained disaster response tasks.

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations of traditional clinical assessments. In this study, we propose a novel pipeline that leverages keystroke dynamics as a non-invasive and scalable biomarker for remote PD screening and telemonitoring. Our methodology involves three main stages: (i) preprocessing of data from four distinct datasets, extracting four temporal signals and addressing class imbalance through the comparison of three methods; (ii) pre-training eight state-of-the-art deep-learning architectures on the two largest datasets, optimizing temporal windowing, stride, and other hyperparameters; (iii) fine-tuning on an intermediate-sized dataset and performing external validation on a fourth, independent cohort. Our results demonstrate that hybrid convolutional-recurrent and transformer-based models achieve strong external validation performance, with AUC-ROC scores exceeding 90% and F1-Score over 70%. Notably, a temporal convolutional model attains an AUC-ROC of 91.14% in external validation, outperforming existing methods that rely solely on internal validation. These findings underscore the potential of keystroke dynamics as a reliable digital biomarker for PD, offering a promising avenue for early detection and continuous monitoring.

Multimodal learning systems often struggle in non-stationary environments due to concept drift, where changing data distributions can degrade performance. Modality-specific drifts and the lack of mechanisms for continuous, stable adaptation compound this challenge. This paper introduces LS-OGD, a novel adaptive control framework for robust multimodal learning in the presence of concept drift. LS-OGD uses an online controller that dynamically adjusts the model's learning rate and the fusion weights between different data modalities in response to detected drift and evolving prediction errors. We prove that under bounded drift conditions, the LS-OGD system's prediction error is uniformly ultimately bounded and converges to zero if the drift ceases. Additionally, we demonstrate that the adaptive fusion strategy effectively isolates and mitigates the impact of severe modality-specific drift, thereby ensuring system resilience and fault tolerance. These theoretical guarantees establish a principled foundation for developing reliable and continuously adapting multimodal learning systems.

This study presents a comprehensive empirical comparison between quantum machine learning (QML) and classical machine learning (CML) approaches in Automated Market Makers (AMM) and Decentralized Finance (DeFi) trading strategies through extensive backtesting on 10 models across multiple cryptocurrency assets. Our analysis encompasses classical ML models (Random Forest, Gradient Boosting, Logistic Regression), pure quantum models (VQE Classifier, QNN, QSVM), hybrid quantum-classical models (QASA Hybrid, QASA Sequence, QuantumRWKV), and transformer models. The results demonstrate that hybrid quantum models achieve superior overall performance with 11.2\% average return and 1.42 average Sharpe ratio, while classical ML models show 9.8\% average return and 1.47 average Sharpe ratio. The QASA Sequence hybrid model achieves the highest individual return of 13.99\% with the best Sharpe ratio of 1.76, demonstrating the potential of quantum-classical hybrid approaches in AMM and DeFi trading strategies.

Developing machine learning models often involves the evaluation of numerous intermediate models. These intermediate models arise during feature engineering, model architecture search, and hyperparam-eter tuning. For instance, during hyperparameter optimization, one might explore various configurations of learning rates, regularization parameters, and network architectures, repeatedly evaluating the model's performance at different training budgets. These accuracy assessments are influenced by the chosen model architecture and parameters, and they change as we alter these factors. Given that these evaluations are often computationally expensive, it is crucial to develop a general framework for optimally allocating resources across the vast space of potential intermediate models.

This study positions large language models (LLMs) as "subjective literary critics" to explore aesthetic preferences and evaluation patterns in literary assessment. Ten Japanese science fiction short stories were translated into English and evaluated by six state-of-the-art LLMs across seven independent sessions. Principal component analysis and clustering techniques revealed significant variations in evaluation consistency (α ranging from 1.00 to 0.35) and five distinct evaluation patterns. Additionally, evaluation variance across stories differed by up to 4.5-fold, with TF-IDF analysis confirming distinctive evaluation vocabularies for each model. Our seven-session within-day protocol using an original Science Fiction corpus strategically minimizes external biases, allowing us to observe implicit value systems shaped by RLHF and their influence on literary judgment. These findings suggest that LLMs may possess individual evaluation characteristics similar to human critical schools, rather than functioning as neutral benchmarkers.

Abstract--Link prediction in graph data uses various algorithms and Graph Nerual Network (GNN) models to predict potential relationships between graph nodes. These techniques have found widespread use in numerous real-world applications, including recommendation systems, community/social networks, and biological structures. However, recent research has highlighted the vulnerability of GNN models to adversarial attacks, such as poisoning and evasion attacks. Addressing the vulnerability of GNN models is crucial to ensure stable and robust performance in GNN applications. Although many works have focused on enhancing the robustness of node classification on GNN models, the robustness of link prediction has received less attention. T o bridge this gap, this article introduces an unweighted graph poisoning attack that leverages meta-learning with weighted scheme strategies to degrade the link prediction performance of GNNs. We conducted comprehensive experiments on diverse datasets across multiple link prediction applications to evaluate the proposed method and its parameters, comparing it with existing approaches under similar conditions. Our results demonstrate that our approach significantly reduces link prediction performance and consistently outperforms other state-of-the-art baselines. Many real-world datasets such as social networks [1], traffic networks [2], biological structures [3], and e-commerce networks [4] can be represented as graphs containing nodes, links, and associated features. The structure of these graphs is dynamic, constantly changing as relationships evolve. Capturing these changes is fundamental to the success of various real-world scenarios, such as community detection and recommendation systems [5].