Visualizing and structuring pairwise dissimilarity data are difficult combinatorial optimization problemsknown as multidimensional scaling or pairwise data clustering. Algorithms for embedding dissimilarity data set in a Euclidian space, for clustering these data and for actively selecting data to support the clustering process are discussed in the maximum entropy framework. Active data selection provides a strategy to discover structure in a data set efficiently with partially unknown data. 1 Introduction Grouping experimental data into compact clusters arises as a data analysis problem in psychology, linguistics,genetics and other experimental sciences. The data which are supposed to be clustered are either given by an explicit coordinate representation (central clustering) or, in the non-metric case, they are characterized by dissimilarity values for pairs of data points (pairwise clustering). In this paper we study algorithms (i) for embedding non-metric data in a D-dimensional Euclidian space, (ii) for simultaneous clustering and embedding of non-metric data, and (iii) for active data selection to determine a particular cluster structure with minimal number of data queries. All algorithms are derived from the maximum entropy principle (Hertz et al., 1991) which guarantees robust statistics (Tikochinsky et al., 1984).

Motivated by difficulties in analog VLSI implementation of back-propagation [Rumelhart et al., 1986] and related algorithms that calculate gradients based on detailed knowledge of the neural network model, there were several similar recent papersproposing to use a parallel [Alspector et al., 1993, Cauwenberghs, 1993, Kirk et al., 1993] or a semi-parallel [Flower and Jabri, 1993] perturbative technique which has the property that it measures (with the physical neural network) rather than calculates the gradient. This technique is closely related to methods of stochastic approximation[Kushner and Clark, 1978] which have been investigated recently by workers in fields other than neural networks.

We introduce a recurrent architecture having a modular structure and we formulate a training procedure based on the EM algorithm. The resulting model has similarities to hidden Markov models, but supports recurrent networks processing style and allows to exploit the supervised learning paradigm while using maximum likelihood estimation. 1 INTRODUCTION Learning problems involving sequentially structured data cannot be effectively dealt with static models such as feedforward networks. Recurrent networks allow to model complex dynamical systems and can store and retrieve contextual information in a flexible way. Up until the present time, research efforts of supervised learning for recurrent networks have almost exclusively focused on error minimization by gradient descent methods. Although effective for learning short term memories, practical difficulties have been reported in training recurrent neural networks to perform tasks in which the temporal contingencies present in the input/output sequences span long intervals (Bengio et al., 1994; Mozer, 1992).

Palo Alto, CA 94304 Abstract We present efficient algorithms for dealing with the problem of missing inputs(incomplete feature vectors) during training and recall. Our approach is based on the approximation of the input data distribution usingParzen windows. For recall, we obtain closed form solutions for arbitrary feedforward networks. For training, we show how the backpropagation step for an incomplete pattern can be approximated by a weighted averaged backpropagation step. The complexity of the solutions for training and recall is independent of the number of missing features.

The TNM staging system has been used since the early 1960's to predict breast cancer patient outcome. In an attempt to increase prognosticaccuracy, many putative prognostic factors have been identified. Because the TNM stage model can not accommodate thesenew factors, the proliferation of factors in breast cancer has lead to clinical confusion. What is required is a new computerized prognostic system that can test putative prognostic factors and integrate the predictive factors with the TNM variables inorder to increase prognostic accuracy. Using the area under the curve of the receiver operating characteristic, we compare the accuracy of the following predictive models in terms of five year breast cancer-specific survival: pTNM staging system, principal componentanalysis, classification and regression trees, logistic regression, cascade correlation neural network, conjugate gradient descent neural, probabilistic neural network, and backpropagation neural network. Several statistical models are significantly more ac- 1064 HarryB.

K-Means is a popular clustering algorithm used in many applications, including the initialization of more computationally expensive algorithms (Gaussian mixtures, Radial Basis Functions, Learning Vector Quantization and some Hidden Markov Models). The practice of this initialization procedure often gives the frustrating feeling that K-Means performs most of the task in a small fraction of the overall time. This motivated us to better understand this convergence speed. A second reason lies in the traditional debate between hard threshold (e.g.

In this paper, we derive classifiers which are winner-take-all (WTA) approximations to a Bayes classifier with Gaussian mixtures for class conditional densities. The derived classifiers include clustering based algorithms like LVQ and k-Means. We propose a constrained rank Gaussian mixtures model and derive a WTA algorithm for it. Our experiments with two speech classification tasks indicate that the constrained rank model and the WTA approximations improve the performance over the unconstrained models. 1 Introduction A classifier assigns vectors from Rn (n dimensional feature space) to one of K classes, partitioning the feature space into a set of K disjoint regions. A Bayesian classifier builds the partition based on a model of the class conditional probability densities of the inputs (the partition is optimal for the given model).

MLP networks provided slightly better risk prediction than conventional logistic regression when used to predict the risk of death, stroke, and renal failure on 1257 patients who underwent coronaryartery bypass operations. Bootstrap sampling was required to compare approaches and regularization provided by early stopping was an important component of improved performance. A simplified approach to generating confidence intervals for MLP risk predictions using an auxiliary "confidence MLP" was also developed. The confidence MLP is trained to reproduce the confidence bounds that were generated during training by 50 MLP networks trained using bootstrap samples. Current research is validating these results usinglarger data sets, exploring approaches to detect outlier patients who are so different fromany training patient that accurate risk prediction is suspect, developing approaches toexplaining which input features are important for an individual patient, and determining why MLP networks provide improved performance.

Satoshi Suzuki Hiroshi Ando ATR Human Information Processing Research Laboratories 2-2 Hikaridai, Seika-cho, Soraku-gun, Kyoto 619-02, Japan satoshi@hip.atr.co.jp, ando@hip.atr.co.jp Abstract This paper presents an unsupervised learning scheme for categorizing 3D objects from their 2D projected images. The scheme exploits an auto-associative network's ability to encode each view of a single object into a representation that indicates its view direction. We propose two models that employ different classification mechanisms; the first model selects an auto-associative network whose recovered view best matches the input view, and the second model is based on a modular architecture whose additional network classifies the views by splitting the input space nonlinearly. We demonstrate the effectiveness of the proposed classification models through simulations using 3D wire-frame objects. 1 INTRODUCTION The human visual system can recognize various 3D (three-dimensional) objects from their 2D (two-dimensional) retinal images although the images vary significantly as the viewpoint changes. Recent computational models have explored how to learn to recognize 3D objects from their projected views (Poggio & Edelman, 1990). Most existing models are, however, based on supervised learning, i.e., during training the teacher tells which object each view belongs to.

Diagnosis of human disease or machine fault is a missing data problem since many variables are initially unknown. Additional information needs to be obtained. The j oint probability distribution of the data can be used to solve this problem. We model this with mixture models whose parameters are estimated by the EM algorithm. This gives the benefit that missing data in the database itself can also be handled correctly. The request for new information to refine the diagnosis is performed using the maximum utility principle. Since the system is based on learning it is domain independent and less labor intensive than expert systems or probabilistic networks. An example using a heart disease database is presented.