We are concerned in this paper with the application of multiple models, specifically the Hierarchical Mixtures of Experts, to time series prediction, specifically the problem of predicting acoustic vectors for use in speech coding. There have been a number of applications of multiple models in time series prediction. A classic example is the Threshold Autoregressive model (TAR) which was used by Tong & 836 S. R. Waterhouse, A. J. Robinson Lim (1980) to predict sunspot activity. More recently, Lewis, Kay and Stevens (in Weigend & Gershenfeld (1994)) describe the use of Multivariate and Regression Splines (MARS) to the prediction of future values of currency exchange rates. Finally, in speech prediction, Cuperman & Gersho (1985) describe the Switched Inter-frame Vector Prediction (SIVP) method which switches between separate linear predictors trained on different statistical classes of speech.

If data collection is costly, there is much to be gained by actively selecting particularly informative data points in a sequential way. In a Bayesian decision-theoretic framework we develop a query selection criterion which explicitly takes into account the intended use of the model predictions. By Markov Chain Monte Carlo methods the necessary quantities can be approximated to a desired precision. As the number of data points grows, the model complexity is modified by a Bayesian model selection strategy. The properties of two versions of the criterion ate demonstrated in numerical experiments.

We present a deterministic annealing variant of the EM algorithm for maximum likelihood parameter estimation problems. In our approach, the EM process is reformulated as the problem of minimizing the thermodynamic free energy by using the principle of maximum entropy and statistical mechanics analogy. Unlike simulated annealing approaches, this minimization is deterministically performed. Moreover, the derived algorithm, unlike the conventional EM algorithm, can obtain better estimates free of the initial parameter values.

The TNM staging system has been used since the early 1960's to predict breast cancer patient outcome. In an attempt to increase prognostic accuracy, many putative prognostic factors have been identified. Because the TNM stage model can not accommodate these new factors, the proliferation of factors in breast cancer has lead to clinical confusion. What is required is a new computerized prognostic system that can test putative prognostic factors and integrate the predictive factors with the TNM variables in order to increase prognostic accuracy. Using the area under the curve of the receiver operating characteristic, we compare the accuracy of the following predictive models in terms of five year breast cancer-specific survival: pTNM staging system, principal component analysis, classification and regression trees, logistic regression, cascade correlation neural network, conjugate gradient descent neural, probabilistic neural network, and backpropagation neural network. Several statistical models are significantly more ac- 1064 Harry B. Burke, David B. Rosen, Philip H. Goodman

We introduce a recurrent architecture having a modular structure and we formulate a training procedure based on the EM algorithm. The resulting model has similarities to hidden Markov models, but supports recurrent networks processing style and allows to exploit the supervised learning paradigm while using maximum likelihood estimation. 1 INTRODUCTION Learning problems involving sequentially structured data cannot be effectively dealt with static models such as feedforward networks. Recurrent networks allow to model complex dynamical systems and can store and retrieve contextual information in a flexible way. Up until the present time, research efforts of supervised learning for recurrent networks have almost exclusively focused on error minimization by gradient descent methods. Although effective for learning short term memories, practical difficulties have been reported in training recurrent neural networks to perform tasks in which the temporal contingencies present in the input/output sequences span long intervals (Bengio et al., 1994; Mozer, 1992).

We present a unifying view of discrete-time operator models used in the context of finite word length linear signal processing. Comparisons are made between the recently presented gamma operator model, and the delta and rho operator models for performing nonlinear system identification and prediction using neural networks. A new model based on an adaptive bilinear transformation which generalizes all of the above models is presented.

We present a graph-based method for rapid, accurate search through prototypes for transformation-invariant pattern classification. Our method has in theory the same recognition accuracy as other recent methods based on ''tangent distance" [Simard et al., 1994], since it uses the same categorization rule. Nevertheless ours is significantly faster during classification because far fewer tangent distances need be computed. Crucial to the success of our system are 1) a novel graph architecture in which transformation constraints and geometric relationships among prototypes are encoded during learning, and 2) an improved graph search criterion, used during classification. These architectural insights are applicable to a wide range of problem domains. Here we demonstrate that on a handwriting recognition task, a basic implementation of our system requires less than half the computation of the Euclidean sorting method. 1 INTRODUCTION In recent years, the crucial issue of incorporating invariances into networks for pattern recognition has received increased attention, most especially due to the work of 666 Alessandro Sperduti, David G. Stork

The TNM staging system has been used since the early 1960's to predict breast cancer patient outcome. In an attempt to increase prognostic accuracy, many putative prognostic factors have been identified. Because the TNM stage model can not accommodate these new factors, the proliferation of factors in breast cancer has lead to clinical confusion. What is required is a new computerized prognostic system that can test putative prognostic factors and integrate the predictive factors with the TNM variables in order to increase prognostic accuracy. Using the area under the curve of the receiver operating characteristic, we compare the accuracy of the following predictive models in terms of five year breast cancer-specific survival: pTNM staging system, principal component analysis, classification and regression trees, logistic regression, cascade correlation neural network, conjugate gradient descent neural, probabilistic neural network, and backpropagation neural network. Several statistical models are significantly more ac- 1064 Harry B. Burke, David B. Rosen, Philip H. Goodman

This paper discusses the linearly weighted combination of estimators in which the weighting functions are dependent on the input. We show that the weighting functions can be derived either by evaluating the input dependent variance of each estimator or by estimating how likely it is that a given estimator has seen data in the region of the input space close to the input pattern. The latter solution is closely related to the mixture of experts approach and we show how learning rules for the mixture of experts can be derived from the theory about learning with missing features. The presented approaches are modular since the weighting functions can easily be modified (no retraining) if more estimators are added. Furthermore, it is easy to incorporate estimators which were not derived from data such as expert systems or algorithms.

The paper presents a rapid speaker-normalization technique based on neural network spectral mapping. The neural network is used as a front-end of a continuous speech recognition system (speakerdependent, HMM-based) to normalize the input acoustic data from a new speaker. The spectral difference between speakers can be reduced using a limited amount of new acoustic data (40 phonetically rich sentences). Recognition error of phone units from the acoustic-phonetic continuous speech corpus APASCI is decreased with an adaptability ratio of 25%. We used local basis networks of elliptical Gaussian kernels, with recursive allocation of units and online optimization of parameters (GRAN model). For this application, the model included a linear term. The results compare favorably with multivariate linear mapping based on constrained orthonormal transformations.