The unprecedented global COVID - 19 pandemic has prompted researchers to investigate both the biochemical changes associated with acute infection and the long - term effects of COVID - 19, with the goal of elucidating underlying mechanisms [ 1 4 ]. Among the diverse biochemical alterations observed in COVID - 19, change s in metabolomic and proteomic profiles have drawn particular attention due to their roles in fundamental biological processes, including protein expression and metabolic pathways [5, 6]. Early in the pandemic, several studies highlighted the significance of certain biomarkers for diagnosing COVID - 19 and assessing disease severity [7, 8]. These initial finding s reveal ed that specific biomarkers are involved in COVID - 19 pathogenesis and correlate with disease severity. S ubsequent research into post - acute sequelae of COVID - 19 (PASC, or long COVID) has further shown that variations in these biomarkers are associated with neurological and respiratory complications [9, 10]. Collectively, these studie s highlight the importance of identifying key biomarkers to support both acute COVID - 19 detection and the understanding of long COVID.

Driver face monitoring system can detect driver fatigue, which is an important factor in a large number of accidents, using computer vision techniques. In this paper we present a real-time technique for driver eye state detection. At first face is detected and the eyes are searched inside face region for tracking. A normalized cross correlation based online dynamic template matching technique with combination of Kalman filter tracking is proposed to track the detected eye positions in the subsequent image frames. Support vector machine with histogram of orientation gradient features is used for classification of state of the eyes as open or closed. If the eye(s) state is detected as closed for a specified amount of time the driver is considered to be sleeping and an alarm will be generated.

Non-adherence to medications is a critical concern since nearly half of patients with chronic illnesses do not follow their prescribed medication regimens, leading to increased mortality, costs, and preventable human distress. Amongst stage 0-3 breast cancer survivors, adherence to long-term adjuvant endocrine therapy (i.e., Tamoxifen and aromatase inhibitors) is associated with a significant increase in recurrence-free survival. This work aims to develop multi-scale models of medication adherence to understand the significance of different factors influencing adherence across varying time frames. We introduce a computational framework guided by Social Cognitive Theory for multi-scale (daily and weekly) modeling of longitudinal medication adherence. Our models employ both dynamic medication-taking patterns in the recent past (dynamic factors) as well as less frequently changing factors (static factors) for adherence prediction. Additionally, we assess the significance of various factors in influencing adherence behavior across different time scales. Our models outperform traditional machine learning counterparts in both daily and weekly tasks in terms of both accuracy and specificity. Daily models achieved an accuracy of 87.25%, and weekly models, an accuracy of 76.04%. Notably, dynamic past medication-taking patterns prove most valuable for predicting daily adherence, while a combination of dynamic and static factors is significant for macro-level weekly adherence patterns.

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources, limiting their accessibility. We propose a hybrid NLP framework that integrates rule-based filtering, a Support Vector Machine (SVM) classifier, and a BERT-based model to improve efficiency while maintaining accuracy. We applied this framework in a dementia identification case study involving 4.9 million veterans with incident hypertension, analyzing 2.1 billion clinical notes. At the patient level, our method achieved a precision of 0.90, a recall of 0.84, and an F1-score of 0.87. Additionally, this NLP approach identified over three times as many dementia cases as structured data methods. All processing was completed in approximately two weeks using a single machine with dual A40 GPUs. This study demonstrates the feasibility of hybrid NLP solutions for large-scale clinical text analysis, making state-of-the-art methods more accessible to healthcare organizations with limited computational resources.

Specialized text classification: an approach to classifying Open Banking transactions Duc Tuyen Ta, Wajdi Ben Saad, Ji Y oung Oh Data Science Team - Oney Bank - France Abstract --With the introduction of the PSD2 regulation in the EU which established the Open Banking framework, a new window of opportunities has opened for banks and fintechs to explore and enrich Bank transaction descriptions with the aim of building a better understanding of customer behavior, while using this understanding to prevent fraud, reduce risks and offer more competitive and tailored services. And although the usage of natural language processing models and techniques has seen an incredible progress in various applications and domains over the past few years, custom applications based on domain-specific text corpus remain unaddressed especially in the banking sector . In this paper, we introduce a language-based Open Banking transaction classification system with a focus on the french market and french language text. The system encompasses data collection, labeling, preprocessing, modeling, and evaluation stages. Unlike previous studies that focus on general classification approaches, this system is specifically tailored to address the challenges posed by training a language model with a specialized text corpus (Banking data in the French context).

SPREV, short for hyperSphere Reduced to two-dimensional Regular Polygon for Visualisation, is a novel dimensionality reduction technique developed to address the challenges of reducing dimensions and visualizing labeled datasets that exhibit a unique combination of three characteristics: small class size, high dimensionality, and low sample size. SPREV is designed not only to uncover but also to visually represent hidden patterns within such datasets. Its distinctive integration of geometric principles, adapted for discrete computational environments, makes it an indispensable tool in the modern data science toolkit, enabling users to identify trends, extract insights, and navigate complex data efficiently and effectively.

Lung cancer is one of the major causes of death worldwide, and Vietnam is not an exception. This disease is the second most common type of cancer globally and the second most common cause of death in Vietnam, just after liver cancer, with 23,797 fatal cases and 26,262 new cases, or 14.4% of the disease in 2020. Recently, with rising disease rates in Vietnam causing a huge public health burden, lung cancer continues to hold the top position in attention and care. Especially together with climate change, under a variety of types of pollution, deforestation, and modern lifestyles, lung cancer risks are on red alert, particularly in Vietnam. To understand more about the severe disease sources in Vietnam from a diversity of key factors, including environmental features and the current health state, with a particular emphasis on Vietnam's distinct socioeconomic and ecological context, we utilize large datasets such as patient health records and environmental indicators containing necessary information, such as deforestation rate, green cover rate, air pollution, and lung cancer risks, that is collected from well-known governmental sharing websites. Then, we process and connect them and apply analytical methods (heatmap, information gain, p-value, spearman correlation) to determine causal correlations influencing lung cancer risks. Moreover, we deploy machine learning (ML) models (Decision Tree, Random Forest, Support Vector Machine, K-mean clustering) to discover cancer risk patterns. Our experimental results, leveraged by the aforementioned ML models to identify the disease patterns, are promising, particularly, the models as Random Forest, SVM, and PCA are working well on the datasets and give high accuracy (99%), however, the K means clustering has very low accuracy (10%) and does not fit the datasets.

Automated scoring (AS) systems are increasingly used for evaluating L2 writing, but require ongoing refinement for construct validity. While prior work suggested lexical bundles (LBs) - recurrent multi-word sequences satisfying certain frequency criteria - could inform assessment, their empirical integration into AS models needs further investigation. This study tested the impact of incorporating LB frequency features into an AS model for TOEFL independent writing tasks. Analyzing a sampled subcorpus (N=1,225 essays, 9 L1s) from the TOEFL11 corpus, scored by ETS-trained raters (Low, Medium, High), 3- to 9-word LBs were extracted, distinguishing prompt-specific from non-prompt types. A baseline Support Vector Machine (SVM) scoring model using established linguistic features (e.g., mechanics, cohesion, sophistication) was compared against an extended model including three aggregate LB frequency features (total prompt, total non-prompt, overall total). Results revealed significant, though generally small-effect, relationships between LB frequency (especially non-prompt bundles) and proficiency (p < .05). Mean frequencies suggested lower proficiency essays used more LBs overall. Critically, the LB-enhanced model improved agreement with human raters (Quadratic Cohen's Kappa +2.05%, overall Cohen's Kappa +5.63%), with notable gains for low (+10.1% exact agreement) and medium (+14.3% Cohen's Kappa) proficiency essays. These findings demonstrate that integrating aggregate LB frequency offers potential for developing more linguistically informed and accurate AS systems, particularly for differentiating developing L2 writers.

Support Vector Machine (SVM) is a popular supervised classification model that works by first finding the margin boundaries for the training data classes and then calculating the decision boundary, which is then used to classify the test data. This study demonstrates limitations of traditional support vector classification which uses cartesian coordinate geometry to find the margin and decision boundaries in an input space using only a few support vectors, without considering data variance and correlation. Subsequently, the study proposes a new Cholesky Kernel that adjusts for the effects of variance-covariance structure of the data in the decision boundary equation and margin calculations. The study demonstrates that SVM model is valid only in the Euclidean space, and the Cholesky kernel obtained by decomposing covariance matrix acts as a transformation matrix, which when applied on the original data transforms the data from the input space to the Euclidean space. The effectiveness of the Cholesky kernel based SVM classifier is demonstrated by classifying the Wisconsin Breast Cancer (Diagnostic) Dataset and comparing with traditional SVM approaches. The Cholesky kernel based SVM model shows marked improvement in the precision, recall and F1 scores compared to linear and other kernel SVMs.

Central bank communication plays a critical role in shaping economic expectations and monetary policy effectiveness. This study applies supervised machine learning techniques to classify the sentiment of press releases from the Bank of Thailand, addressing gaps in research that primarily focus on lexicon-based approaches. My findings show that supervised learning can be an effective method, even with smaller datasets, and serves as a starting point for further automation. However, achieving higher accuracy and better generalization requires a substantial amount of labeled data, which is time-consuming and demands expertise. Using models such as Na\"ive Bayes, Random Forest and SVM, this study demonstrates the applicability of machine learning for central bank sentiment analysis, with English-language communications from the Thai Central Bank as a case study.