Spectral clustering (SC) is one of the most popular clustering methods and often outperforms traditional clustering methods. SC uses the eigenvectors of a Laplacian matrix calculated from a similarity matrix of a dataset. SC has serious drawbacks that are the significant increase in the computational complexity derived from the eigendecomposition and the memory space complexities to store the similarity matrix. To address the issues, I develop a new approximate spectral clustering using the network generated by growing neural gas (GNG), called ASC with GNG in this study. The proposed method uses not only reference vectors for vector quantization but also the topology of the network for extraction of the topological relationship between data points in a dataset. The similarity matrix used by ASC with GNG is made from both the reference vectors and the topology of the network generated by GNG. Using the network generated from a dataset by GNG, we achieve to reduce the computational and space complexities and to improve clustering quality. This paper demonstrates that the proposed method effectively reduces the computational time. Moreover, the results of this study show that the proposed method displays equal to or better performance of clustering than SC.

Dynamical systems arise in a wide variety of mathematical models from science and engineering. A common challenge is to quantify uncertainties on model inputs (parameters) that correspond to a quantitative characterization of uncertainties on observable Quantities of Interest (QoI). To this end, we consider a stochastic inverse problem (SIP) with a solution described by a pullback probability measure. We call this an observation-consistent solution, as its subsequent push-forward through the QoI map matches the observed probability distribution on model outputs. A distinction is made between QoI useful for solving the SIP and arbitrary model output data. In dynamical systems, model output data are often given as a series of state variable responses recorded over a particular time window. Consequently, the dimension of output data can easily exceed $\mathcal{O}(1E4)$ or more due to the frequency of observations, and the correct choice or construction of a QoI from this data is not self-evident. We present a new framework, Learning Uncertain Quantities (LUQ), that facilitates the tractable solution of SIPs for dynamical systems. Given ensembles of predicted (simulated) time series and (noisy) observed data, LUQ provides routines for filtering data, unsupervised learning of the underlying dynamics, classifying observations, and feature extraction to learn the QoI map. Subsequently, time series data are transformed into samples of the underlying predicted and observed distributions associated with the QoI so that solutions to the SIP are computable. Following the introduction and demonstration of LUQ, numerical results from several SIPs are presented for a variety of dynamical systems arising in the life and physical sciences. For scientific reproducibility, we provide links to our Python implementation of LUQ and to all data and scripts required to reproduce the results in this manuscript.

This thesis focuses on the research and development of the Hemodynamic Tissue Signature (HTS) method: an unsupervised machine learning approach to describe the vascular heterogeneity of glioblastomas by means of perfusion MRI analysis. The HTS builds on the concept of habitats. An habitat is defined as a sub-region of the lesion with a particular MRI profile describing a specific physiological behavior. The HTS method delineates four habitats within the glioblastoma: the High Angiogenic Tumor (HAT) habitat, as the most perfused region of the enhancing tumor; the Low Angiogenic Tumor (LAT) habitat, as the region of the enhancing tumor with a lower angiogenic profile; the potentially Infiltrated Peripheral Edema (IPE) habitat, as the non-enhancing region adjacent to the tumor with elevated perfusion indexes; and the Vasogenic Peripheral Edema (VPE) habitat, as the remaining edema of the lesion with the lowest perfusion profile. The results of this thesis have been published in ten scientific contributions, including top-ranked journals and conferences in the areas of Medical Informatics, Statistics and Probability, Radiology & Nuclear Medicine, Machine Learning and Data Mining and Biomedical Engineering. An industrial patent registered in Spain (ES201431289A), Europe (EP3190542A1) and EEUU (US20170287133A1) was also issued, summarizing the efforts of the thesis to generate tangible assets besides the academic revenue obtained from research publications. Finally, the methods, technologies and original ideas conceived in this thesis led to the foundation of ONCOANALYTICS CDX, a company framed into the business model of companion diagnostics for pharmaceutical compounds, thought as a vehicle to facilitate the industrialization of the ONCOhabitats technology.

Community detection is a fundamental problem in the analysis of complex networks. It is the analogue of clustering in network data mining. Within community detection methods, hierarchical algorithms are popular. However, their iterative nature and the need to recompute the structural properties used to split the network (i.e. edge betweenness in Girvan and Newman's algorithm), make them unsuitable for large network data sets. In this paper, we study how local structural network properties can be used as proxies to improve the efficiency of hierarchical community detection while, at the same time, achieving competitive results in terms of modularity. In particular, we study the potential use of the structural properties commonly used to perform local link prediction, a supervised learning problem where community structure is relevant, as nodes are prone to establish new links with other nodes within their communities. In addition, we check the performance impact of network pruning heuristics as an ancillary tactic to make hierarchical community detection more efficient

This master's thesis work has the objective of performing an analysis of the methods for detecting communities in networks. As an initial part, I study of the main features of graph theory and communities, as well as common measures in this problem. Subsequently, I was performed a review of the main methods of detecting communities, developing a classification, taking into account its characteristics and computational complexity for the detection of strengths and weaknesses in the methods, as well as later works. Then, study the problem of classification of a clustering method, this in order to evaluate the quality of the communities detected by analyzing different measures. Finally conclusions are elaborated and possible lines of work that can be derived.

If you've just started to explore the ways that machine learning can impact your business, the first questions you're likely to come across are what are all of the different types of machine learning algorithms, what are they good for, and which one should I choose for my project? This post will help you answer those questions. There are a few different ways to categorize machine learning algorithms. One way is based on what the training data looks like. Another way to classify algorithms--and one that's more practical from a business perspective--is to categorize them based on how they work and what kinds of problems they can solve, which is what we'll do here.

Real-time ridesharing systems such as UberPool, Lyft Line, GrabShare have become hugely popular as they reduce the costs for customers, improve per trip revenue for drivers and reduce traffic on the roads by grouping customers with similar itineraries. The key challenge in these systems is to group the "right" requests to travel together in the "right" available vehicles in real-time, so that the objective (e.g., requests served, revenue or delay) is optimized. This challenge has been addressed in existing work by: (i) generating as many relevant feasible (with respect to the available delay for customers) combinations of requests as possible in real-time; and then (ii) optimizing assignment of the feasible request combinations to vehicles. Since the number of request combinations increases exponentially with the increase in vehicle capacity and number of requests, unfortunately, such approaches have to employ ad hoc heuristics to identify a subset of request combinations for assignment. Our key contribution is in developing approaches that employ zone (abstraction of individual locations) paths instead of request combinations. Zone paths allow for generation of significantly more "relevant" combinations (in comparison to ad hoc heuristics) in real-time than competing approaches due to two reasons: (i) Each zone path can typically represent multiple request combinations; (ii) Zone paths are generated using a combination of offline and online methods. Specifically, we contribute both myopic (ridesharing assignment focussed on current requests only) and non-myopic (ridesharing assignment considers impact on expected future requests) approaches that employ zone paths. In our experimental results, we demonstrate that our myopic approach outperforms (with respect to both objective and runtime) the current best myopic approach for ridesharing on both real-world and synthetic datasets.

Finite mixture models, typically Gaussian mixtures, are well known and widely used as model-based clustering. In practical situations, there are many non-Gaussian data that are heavy-tailed and/or asymmetric. Normal inverse Gaussian (NIG) distributions are normal-variance mean which mixing densities are inverse Gaussian distributions and can be used for both haavy-tail and asymmetry. For NIG mixture models, both expectation-maximization method and variational Bayesian (VB) algorithms have been proposed. However, the existing VB algorithm for NIG mixture have a disadvantage that the shape of the mixing density is limited. In this paper, we propose another VB algorithm for NIG mixture that improves on the shortcomings. We also propose an extension of Dirichlet process mixture models to overcome the difficulty in determining the number of clusters in finite mixture models. We evaluated the performance with artificial data and found that it outperformed Gaussian mixtures and existing implementations for NIG mixtures, especially for highly non-normative data.

Clustering techniques attempt to group objects with similar properties into a cluster. Clustering the nodes of an attributed graph, in which each node is associated with a set of feature attributes, has attracted significant attention. Graph convolutional networks (GCNs) represent an effective approach for integrating the two complementary factors of node attributes and structural information for attributed graph clustering. However, oversmoothing of GCNs produces indistinguishable representations of nodes, such that the nodes in a graph tend to be grouped into fewer clusters, and poses a challenge due to the resulting performance drop. In this study, we propose a smoothness sensor for attributed graph clustering based on adaptive smoothness-transition graph convolutions, which senses the smoothness of a graph and adaptively terminates the current convolution once the smoothness is saturated to prevent oversmoothing. Furthermore, as an alternative to graph-level smoothness, a novel fine-gained node-wise level assessment of smoothness is proposed, in which smoothness is computed in accordance with the neighborhood conditions of a given node at a certain order of graph convolution. In addition, a self-supervision criterion is designed considering both the tightness within clusters and the separation between clusters to guide the whole neural network training process. Experiments show that the proposed methods significantly outperform 12 other state-of-the-art baselines in terms of three different metrics across four benchmark datasets. In addition, an extensive study reveals the reasons for their effectiveness and efficiency.

In the WWW (World Wide Web), dynamic development and spread of data has resulted a tremendous amount of information available on the Internet, yet user is unable to find relevant information in a short span of time. Consequently, a system called recommendation system developed to help users find their infromation with ease through their browsing activities. In other words, recommender systems are tools for interacting with large amount of information that provide personalized view for prioritizing items likely to be of keen for users. They have developed over the years in artificial intelligence techniques that include machine learning and data mining amongst many to mention. Furthermore, the recommendation systems have personalized on an e-commerce, on-line applications such as Amazon.com, Netflix, and Booking.com. As a result, this has inspired many researchers to extend the reach of recommendation systems into new sets of challenges and problem areas that are yet to be truly solved, primarily a problem with the case of making a recommendation to a new user that is called cold-state (i.e. cold-start) user problem where the new user might likely not yield much of information searched. Therfore, the purpose of this paper is to tackle the said cold-start problem with a few effecient methods and challenges, as well as identify and overview the current state of recommendation system as a whole