We introduce hierarchically supervised latent Dirichlet allocation (HSLDA), a model for hierarchically and multiply labeled bag-of-word data. Examples of such data include web pages and their placement in directories, product descriptions and associated categories from product hierarchies, and free-text clinical records and their assigned diagnosis codes. Out-of-sample label prediction is the primary goal of this work, but improved lower-dimensional representations of the bagof-word data are also of interest. We demonstrate HSLDA on large-scale data from clinical document labeling and retail product categorization tasks. We show that leveraging the structure from hierarchical labels improves out-of-sample label prediction substantially when compared to models that do not.

Alzheimer's Disease (AD) is the most common form of dementia in the United States. Sleep is one of the lifestyle-related factors that has been shown critical for optimal cognitive function in old age. However, there is a lack of research studying the association between sleep and AD incidence. A major bottleneck for conducting such research is that the traditional way to acquire sleep information is time-consuming, inefficient, non-scalable, and limited to patients' subjective experience. A gold standard dataset is created from manual annotation of 570 randomly sampled clinical note documents from the adSLEEP, a corpus of 192,000 de-identified clinical notes of 7,266 AD patients retrieved from the University of Pittsburgh Medical Center (UPMC). We developed a rule-based Natural Language Processing (NLP) algorithm, machine learning models, and Large Language Model(LLM)-based NLP algorithms to automate the extraction of sleep-related concepts, including snoring, napping, sleep problem, bad sleep quality, daytime sleepiness, night wakings, and sleep duration, from the gold standard dataset. Rule-based NLP algorithm achieved the best performance of F1 across all sleep-related concepts. In terms of Positive Predictive Value (PPV), rule-based NLP algorithm achieved 1.00 for daytime sleepiness and sleep duration, machine learning models: 0.95 and for napping, 0.86 for bad sleep quality and 0.90 for snoring; and LLAMA2 with finetuning achieved PPV of 0.93 for Night Wakings, 0.89 for sleep problem, and 1.00 for sleep duration. The results show that the rule-based NLP algorithm consistently achieved the best performance for all sleep concepts. This study focused on the clinical notes of patients with AD, but could be extended to general sleep information extraction for other diseases.

In this work, we study the out-of-distribution (OOD) detection problem through the use of the feature space of a pre-trained deep classifier. We show that learning the density of in-distribution (ID) features with an energy-based models (EBM) leads to competitive detection results. However, we found that the non-mixing of MCMC sampling during the EBM's training undermines its detection performance. To overcome this an energy-based correction of a mixture of class-conditional Gaussian distributions. We obtains favorable results when compared to a strong baseline like the KNN detector on the CIFAR-10/CIFAR-100 OOD detection benchmarks.

The sheer number of nodes continues to increase in todays supercomputers, the first half of Trinity alone contains more than 9400 compute nodes. Since the speed of todays clusters are limited by the slowest nodes, it more important than ever to identify slow nodes, improve their performance if it can be done, and assure minimal usage of slower nodes during performance critical runs. This is an ongoing maintenance task that occurs on a regular basis and, therefore, it is important to minimize the impact upon its users by assessing and addressing slow performing nodes and mitigating their consequences while minimizing down time. These issues can be solved, in large part, through a systematic application of fast running hardware assessment tests, the application of Machine Learning, and making use of performance data to increase efficiency of large clusters. Proxy applications utilizing both MPI and OpenMP were developed to produce data as a substitute for long runtime applications to evaluate node performance. Machine learning is applied to identify underperforming nodes, and policies are being discussed to both minimize the impact of underperforming nodes and increase the efficiency of the system. In this paper, I will describe the process used to produce quickly performing proxy tests, consider various methods to isolate the outliers, and produce ordered lists for use in scheduling to accomplish this task.

Bladder cancer, the leading urinary tract cancer, is responsible for 15 deaths daily in the UK. This cancer predominantly manifests as non-muscle-invasive bladder cancer (NMIBC), characterised by tumours not yet penetrating the muscle layer of the bladder wall. NMIBC is plagued by a very high recurrence rate of 70-80% and hence the costliest treatments. Current tools for predicting recurrence use scoring systems that overestimate risk and have poor accuracy. Inaccurate and delayed prediction of recurrence significantly elevates the likelihood of mortality. Accurate prediction of recurrence is hence vital for cost-effective management and treatment planning. This is where Machine learning (ML) techniques have emerged as a promising approach for predicting NMIBC recurrence by leveraging molecular and clinical data. This review provides a comprehensive analysis of ML approaches for predicting NMIBC recurrence. Our systematic evaluation demonstrates the potential of diverse ML algorithms and markers, including radiomic, clinical, histopathological, genomic, and biochemical data in enhancing recurrence prediction and personalised patient management. We summarise various prediction tasks, data modalities, and ML models used, highlighting their performance, limitations, and future directions of incorporating cost-effectiveness. Challenges related to generalisability and interpretability of artificial intelligent models are discussed, emphasising the need for collaborative efforts and robust datasets.

Deep neural networks have been very successful in a wide variety of tasks over the last two decades. In large part their success is attributed to their ability to perform very well without major manual feature engineering required when compared to more classical techniques. The hierarchical structure of the networks weighs and extracts important features automatically from the data during the learning process [GBC16]. However, the exact architecture of the neural network still has to be prescribed manually by the user. This led to the development of so-called auto-ML techniques that aim to automate this process. In the context of deep neural networks, auto-ML has a very large overlap with neural architecture search (NAS), itself having a large overlap with hyperparameter optimization.

The proliferation of large language models (LLMs) in generating content raises concerns about text copyright. Watermarking methods, particularly logit-based approaches, embed imperceptible identifiers into text to address these challenges. However, the widespread use of watermarking across diverse LLMs has led to an inevitable issue known as watermark collision during common tasks like question answering and paraphrasing. This study focuses on dual watermark collisions, where two watermarks are present simultaneously in the same text. The research demonstrates that watermark collision poses a threat to detection performance for detectors of both upstream and downstream watermark algorithms.

Vision-and-Language Navigation in Continuous Environments (VLN-CE) is one of the most intuitive yet challenging embodied AI tasks. Agents are tasked to navigate towards a target goal by executing a set of low-level actions, following a series of natural language instructions. All VLN-CE methods in the literature assume that language instructions are exact. However, in practice, instructions given by humans can contain errors when describing a spatial environment due to inaccurate memory or confusion. Current VLN-CE benchmarks do not address this scenario, making the state-of-the-art methods in VLN-CE fragile in the presence of erroneous instructions from human users. For the first time, we propose a novel benchmark dataset that introduces various types of instruction errors considering potential human causes. This benchmark provides valuable insight into the robustness of VLN systems in continuous environments. We observe a noticeable performance drop (up to -25%) in Success Rate when evaluating the state-of-the-art VLN-CE methods on our benchmark. Moreover, we formally define the task of Instruction Error Detection and Localization, and establish an evaluation protocol on top of our benchmark dataset. We also propose an effective method, based on a cross-modal transformer architecture, that achieves the best performance in error detection and localization, compared to baselines. Surprisingly, our proposed method has revealed errors in the validation set of the two commonly used datasets for VLN-CE, i.e., R2R-CE and RxR-CE, demonstrating the utility of our technique in other tasks. Code and dataset will be made available upon acceptance at https://intelligolabs.github.io/R2RIE-CE

However, due to a lack of mental health awareness and fear of stigma, many patients do not actively seek diagnosis and treatment, leading to detrimental outcomes. Depression detection aims to determine whether an individual suffers from depression by analyzing their history of posts on social media, which can significantly aid in early detection and intervention. It mainly faces two key challenges: 1) it requires professional medical knowledge, and 2) it necessitates both high accuracy and explainability. To address it, we propose a novel depression detection system called DORIS, combining medical knowledge and the recent advances in large language models (LLMs). Specifically, to tackle the first challenge, we proposed an LLM-based solution to first annotate whether high-risk texts meet medical diagnostic criteria. Further, we retrieve texts with high emotional intensity and summarize critical information from the historical mood records of users, so-called mood courses. To tackle the second challenge, we combine LLM and traditional classifiers to integrate medical knowledge-guided features, for which the model can also explain its prediction results, achieving both high accuracy and explainability. Extensive experimental results on benchmarking datasets show that, compared to the current best baseline, our approach improves by 0.036 in AUPRC, which can be considered significant, demonstrating the effectiveness of our approach and its high value as an NLP application.

In an effort to improve the accuracy of credit lending decisions, many financial intuitions are now using predictions from machine learning models. While such predictions enjoy many advantages, recent research has shown that the predictions have the potential to be biased and unfair towards certain subgroups of the population. To combat this, several techniques have been introduced to help remove the bias and improve the overall fairness of the predictions. We introduce a new fairness technique, called \textit{Subgroup Threshold Optimizer} (\textit{STO}), that does not require any alternations to the input training data nor does it require any changes to the underlying machine learning algorithm, and thus can be used with any existing machine learning pipeline. STO works by optimizing the classification thresholds for individual subgroups in order to minimize the overall discrimination score between them. Our experiments on a real-world credit lending dataset show that STO can reduce gender discrimination by over 90\%.