We propose a constraint-based algorithm, which automatically determines causal relevance thresholds, to infer causal networks from data. We call these topological thresholds. We present two methods for determining the threshold: the first seeks a set of edges that leaves no disconnected nodes in the network; the second seeks a causal large connected component in the data. We tested these methods both for discrete synthetic and real data, and compared the results with those obtained for the PC algorithm, which we took as the benchmark. We show that this novel algorithm is generally faster and more accurate than the PC algorithm. The algorithm for determining the thresholds requires choosing a measure of causality. We tested our methods for Fisher Correlations, commonly used in PC algorithm (for instance in \cite{kalisch2005}), and further proposed a discrete and asymmetric measure of causality, that we called Net Influence, which provided very good results when inferring causal networks from discrete data. This metric allows for inferring directionality of the edges in the process of applying the thresholds, speeding up the inference of causal DAGs.

The training-conditional coverage performance of the conformal prediction is known to be empirically sound. Recently, there have been efforts to support this observation with theoretical guarantees. The training-conditional coverage bounds for jackknife+ and full-conformal prediction regions have been established via the notion of $(m,n)$-stability by Liang and Barber~[2023]. Although this notion is weaker than uniform stability, it is not clear how to evaluate it for practical models. In this paper, we study the training-conditional coverage bounds of full-conformal, jackknife+, and CV+ prediction regions from a uniform stability perspective which is known to hold for empirical risk minimization over reproducing kernel Hilbert spaces with convex regularization. We derive coverage bounds for finite-dimensional models by a concentration argument for the (estimated) predictor function, and compare the bounds with existing ones under ridge regression.

This paper represents an analysis on the momentum of tennis match. And due to Generalization performance of it, it can be helpful in constructing a system to predict the result of sports game and analyze the performance of player based on the Technical statistics. We First use hidden markov models to predict the momentum which is defined as the performance of players. Then we use Xgboost to prove the significance of momentum. Finally we use LightGBM to evaluate the performance of our model and use SHAP feature importance ranking and weight analysis to find the key points that affect the performance of players.

In this study, we delve into the intricate relationships between diabetes and a range of health indicators, with a particular focus on the newly added variable of income. Utilizing data from the 2015 Behavioral Risk Factor Surveillance System (BRFSS), we analyze the impact of various factors such as blood pressure, cholesterol, BMI, smoking habits, and more on the prevalence of diabetes. Our comprehensive analysis not only investigates each factor in isolation but also explores their interdependencies and collective influence on diabetes. A novel aspect of our research is the examination of income as a determinant of diabetes risk, which to the best of our knowledge has been relatively underexplored in previous studies. We employ statistical and machine learning techniques to unravel the complex interplay between socio-economic status and diabetes, providing new insights into how financial well-being influences health outcomes. Our research reveals a discernible trend where lower income brackets are associated with a higher incidence of diabetes. In analyzing a blend of 33 variables, including health factors and lifestyle choices, we identified that features such as high blood pressure, high cholesterol, cholesterol checks, income, and Body Mass Index (BMI) are of considerable significance. These elements stand out among the myriad of factors examined, suggesting that they play a pivotal role in the prevalence and management of diabetes.

As a prevalent and dynamically regulated epigenetic modification, 5-formylcytidine (f5C) is crucial in various biological processes. However, traditional experimental methods for f5C detection are often laborious and time-consuming, limiting their ability to map f5C sites across the transcriptome comprehensively. While computational approaches offer a cost-effective and high-throughput alternative, no recognition model for f5C has been developed to date. Drawing inspiration from language models in natural language processing, this study presents f5C-finder, an ensemble neural network-based model utilizing multi-head attention for the identification of f5C. Five distinct feature extraction methods were employed to construct five individual artificial neural networks, and these networks were subsequently integrated through ensemble learning to create f5C-finder. 10-fold cross-validation and independent tests demonstrate that f5C-finder achieves state-of-the-art (SOTA) performance with AUC of 0.807 and 0.827, respectively. The result highlights the effectiveness of biological language model in capturing both the order (sequential) and functional meaning (semantics) within genomes. Furthermore, the built-in interpretability allows us to understand what the model is learning, creating a bridge between identifying key sequential elements and a deeper exploration of their biological functions.

Intrusion detection is a long standing and crucial problem in security. A system capable of detecting intrusions automatically is on great demand in enterprise security solutions. Existing solutions rely heavily on hand-crafted rules designed by security operators, which suffer from high false negative rates and poor generalization ability to new, zero-day attacks at scale. AI and machine learning offer promising solutions to address the issues, by inspecting abnormal user behaviors intelligently and automatically from data. However, existing learning-based intrusion detection systems in the literature are mostly designed for small data, and they lack the ability to leverage the power of big data in cloud environments. In this paper, we target at this problem and introduce an intrusion detection system which incorporates large-scale pre-training, so as to train a large language model based on tens of millions of command lines for AI-based intrusion detection. Experiments performed on 30 million training samples and 10 million test samples verify the effectiveness of our solution.

Intrusion detection systems (IDS) for the Internet of Things (IoT) systems can use AI-based models to ensure secure communications. IoT systems tend to have many connected devices producing massive amounts of data with high dimensionality, which requires complex models. Complex models have notorious problems such as overfitting, low interpretability, and high computational complexity. Adding model complexity penalty (i.e., regularization) can ease overfitting, but it barely helps interpretability and computational efficiency. Feature engineering can solve these issues; hence, it has become critical for IDS in large-scale IoT systems to reduce the size and dimensionality of data, resulting in less complex models with excellent performance, smaller data storage, and fast detection. This paper proposes a new feature engineering method called LEMDA (Light feature Engineering based on the Mean Decrease in Accuracy). LEMDA applies exponential decay and an optional sensitivity factor to select and create the most informative features. The proposed method has been evaluated and compared to other feature engineering methods using three IoT datasets and four AI/ML models. The results show that LEMDA improves the F1 score performance of all the IDS models by an average of 34% and reduces the average training and detection times in most cases.

The COVID19 pandemic had enormous economic and societal consequences. Contact tracing is an effective way to reduce infection rates by detecting potential virus carriers early. However, this was not generally adopted in the recent pandemic, and privacy concerns are cited as the most important reason. We substantially improve the privacy guarantees of the current state of the art in decentralized contact tracing. Whereas previous work was based on statistical inference only, we augment the inference with a learned neural network and ensure that this neural augmentation satisfies differential privacy. In a simulator for COVID19 even at ε = 1 per message, this can significantly improve the detection of potentially infected individuals and, as a result of targeted testing, reduce infection rates. The COVID19 pandemic had enormous consequences (Kim et al., 2022; Kaye et al., 2021; Boden et al., 2021; Vindegaard & Benros, 2020). Contact-tracing algorithms could make early predictions of virus carriers, signaling individuals to get tested and thereby reducing the spread of the virus (Baker et al., 2021).

Arrhythmias, detectable via electrocardiograms (ECGs), pose significant health risks, emphasizing the need for robust automated identification techniques. Although traditional deep learning methods have shown potential, recent advances in graph-based strategies are aimed at enhancing arrhythmia detection performance. However, effectively representing ECG signals as graphs remains a challenge. This study explores graph representations of ECG signals using Visibility Graph (VG) and Vector Visibility Graph (VVG), coupled with Graph Convolutional Networks (GCNs) for arrhythmia classification. Through experiments on the MIT-BIH dataset, we investigated various GCN architectures and preprocessing parameters. The results reveal that GCNs, when integrated with VG and VVG for signal graph mapping, can classify arrhythmias without the need for preprocessing or noise removal from ECG signals. While both VG and VVG methods show promise, VG is notably more efficient. The proposed approach was competitive compared to baseline methods, although classifying the S class remains challenging, especially under the inter-patient paradigm. Computational complexity, particularly with the VVG method, required data balancing and sophisticated implementation strategies. The source code is publicly available for further research and development at https://github.com/raffoliveira/VG_for_arrhythmia_classification_with_GCN.

Artificial intelligence supports healthcare professionals with predictive modeling, greatly transforming clinical decision-making. This study addresses the crucial need for fairness and explainability in AI applications within healthcare to ensure equitable outcomes across diverse patient demographics. By focusing on the predictive modeling of sepsis-related mortality, we propose a method that learns a performance-optimized predictive model and then employs the transfer learning process to produce a model with better fairness. Our method also introduces a novel permutation-based feature importance algorithm aiming at elucidating the contribution of each feature in enhancing fairness on predictions. Unlike existing explainability methods concentrating on explaining feature contribution to predictive performance, our proposed method uniquely bridges the gap in understanding how each feature contributes to fairness. This advancement is pivotal, given sepsis's significant mortality rate and its role in one-third of hospital deaths. Our method not only aids in identifying and mitigating biases within the predictive model but also fosters trust among healthcare stakeholders by improving the transparency and fairness of model predictions, thereby contributing to more equitable and trustworthy healthcare delivery.