Accurate lung nodule detection for computed tomography (CT) scan imagery is challenging in real-world settings due to the sparse occurrence of nodules and similarity to other anatomical structures. In a typical positive case, nodules may appear in as few as 3% of CT slices, complicating detection. This paper presents a novel approach to lung tumor detection in CT data by framing the task as anomaly detection, targeting rare nodule occurrences in a predominantly normal dataset. Our novel method, named Lung-DETR combines Deformable Detection Transformer, Focal Loss, and Maximum Intensity Projection into a unified framework for sparse lung nodule detection. A 7.5mm Maximum Intensity Projection (MIP) is utilized to combine adjacent lung slices, decreasing nodule sparsity and enhancing spatial context to allow for better differentiation between nodules, bronchioles, and other complex vascular structures. Lung-DETR is trained with a custom focal loss function to better handle the imbalanced dataset, and outputs bounding boxes around detected nodules. Our model achieves an F1 score of 94.2% (95.2% recall, 93.3% precision) on the LUNA16 dataset, with test dataset nodule sparsity of 4% that is reflective of real-world clinical data.

Diffusion models have achieved notable success in image generation, but they remain highly vulnerable to backdoor attacks, which compromise their integrity by producing specific undesirable outputs when presented with a pre-defined trigger. In this paper, we investigate how to protect diffusion models from this dangerous threat. Specifically, we propose TERD, a backdoor defense framework that builds unified modeling for current attacks, which enables us to derive an accessible reversed loss. A trigger reversion strategy is further employed: an initial approximation of the trigger through noise sampled from a prior distribution, followed by refinement through differential multi-step samplers. Additionally, with the reversed trigger, we propose backdoor detection from the noise space, introducing the first backdoor input detection approach for diffusion models and a novel model detection algorithm that calculates the KL divergence between reversed and benign distributions. Extensive evaluations demonstrate that TERD secures a 100% True Positive Rate (TPR) and True Negative Rate (TNR) across datasets of varying resolutions. TERD also demonstrates nice adaptability to other Stochastic Differential Equation (SDE)-based models. Our code is available at https://github.com/PKU-ML/TERD.

This paper presents a novel Collaborative Cyberattack Detection (CCD) system aimed at enhancing the security of blockchain-based data-sharing networks by addressing the complex challenges associated with noise addition in federated learning models. Leveraging the theoretical principles of differential privacy, our approach strategically integrates noise into trained sub-models before reconstructing the global model through transmission. We systematically explore the effects of various noise types, i.e., Gaussian, Laplace, and Moment Accountant, on key performance metrics, including attack detection accuracy, deep learning model convergence time, and the overall runtime of global model generation. Our findings reveal the intricate trade-offs between ensuring data privacy and maintaining system performance, offering valuable insights into optimizing these parameters for diverse CCD environments. Through extensive simulations, we provide actionable recommendations for achieving an optimal balance between data protection and system efficiency, contributing to the advancement of secure and reliable blockchain networks.

Clinically deployed deep learning-based segmentation models are known to fail on data outside of their training distributions. While clinicians review the segmentations, these models tend to perform well in most instances, which could exacerbate automation bias. Therefore, detecting out-of-distribution images at inference is critical to warn the clinicians that the model likely failed. This work applied the Mahalanobis distance (MD) post hoc to the bottleneck features of four Swin UNETR and nnU-net models that segmented the liver on T1-weighted magnetic resonance imaging and computed tomography. By reducing the dimensions of the bottleneck features with either principal component analysis or uniform manifold approximation and projection, images the models failed on were detected with high performance and minimal computational load. In addition, this work explored a non-parametric alternative to the MD, a k-th nearest neighbors distance (KNN). KNN drastically improved scalability and performance over MD when both were applied to raw and average-pooled bottleneck features.

Advanced Driver Assistance Systems (ADAS) alert drivers during safety-critical scenarios but often provide superfluous alerts due to a lack of consideration for drivers' knowledge or scene awareness. Modeling these aspects together in a data-driven way is challenging due to the scarcity of critical scenario data with in-cabin driver state and world state recorded together. We explore the benefits of driver modeling in the context of Forward Collision Warning (FCW) systems. Working with real-world video dataset of on-road FCW deployments, we collect observers' subjective validity rating of the deployed alerts. We also annotate participants' gaze-to-objects and extract 3D trajectories of the ego vehicle and other vehicles semi-automatically. We generate a risk estimate of the scene and the drivers' perception in a two step process: First, we model the movement of vehicles in a given scenario as a joint trajectory forecasting problem. Then, we reason about the drivers' risk perception of the scene by counterfactually modifying the input to the forecasting model to represent the drivers' actual observations of vehicles in the scene. The difference in these behaviours gives us an estimate of driver behaviour that accounts for their actual (inattentive) observations and their downstream effect on overall scene risk. We compare both a learned scene representation as well as a more traditional ``worse-case'' deceleration model to achieve the future trajectory forecast. Our experiments show that using this risk formulation to generate FCW alerts may lead to improved false positive rate of FCWs and improved FCW timing.

Early prediction of seizures and timely interventions are vital for improving patients' quality of life. While seizure prediction has been shown in software-based implementations, to enable timely warnings of upcoming seizures, prediction must be done on an edge device to reduce latency. Ideally, such devices must also be low-power and track long-term drifts to minimize maintenance from the user. This work presents SPIRIT: Stochastic-gradient-descent-based Predictor with Integrated Retraining and In situ accuracy Tuning. SPIRIT is a complete system-on-a-chip (SoC) integrating an unsupervised online-learning seizure prediction classifier with eight 14.4 uW, 0.057 mm2, 90.5 dB dynamic range, Zoom Analog Frontends. SPIRIT achieves, on average, 97.5%/96.2% sensitivity/specificity respectively, predicting seizures an average of 8.4 minutes before they occur. Through its online learning algorithm, prediction accuracy improves by up to 15%, and prediction times extend by up to 7x, without any external intervention. Its classifier consumes 17.2 uW and occupies 0.14 mm2, the lowest reported for a prediction classifier by >134x in power and >5x in area. SPIRIT is also at least 5.6x more energy efficient than the state-of-the-art.

There is a great need to accurately predict short-term precipitation, which has socioeconomic effects such as agriculture and disaster prevention. Recently, the forecasting models have employed multi-source data as the multi-modality input, thus improving the prediction accuracy. However, the prevailing methods usually suffer from the desynchronization of multi-source variables, the insufficient capability of capturing spatio-temporal dependency, and unsatisfactory performance in predicting extreme precipitation events. To fix these problems, we propose a short-term precipitation forecasting model based on spatio-temporal alignment attention, with SATA as the temporal alignment module and STAU as the spatio-temporal feature extractor to filter high-pass features from precipitation signals and capture multi-term temporal dependencies. Based on satellite and ERA5 data from the southwestern region of China, our model achieves improvements of 12.61\% in terms of RMSE, in comparison with the state-of-the-art methods.

Ensuring fairness in transaction fraud detection models is vital due to the potential harms and legal implications of biased decision-making. Despite extensive research on algorithmic fairness, there is a notable gap in the study of bias in fraud detection models, mainly due to the field's unique challenges. These challenges include the need for fairness metrics that account for fraud data's imbalanced nature and the tradeoff between fraud protection and service quality. To address this gap, we present a comprehensive fairness evaluation of transaction fraud models using public synthetic datasets, marking the first algorithmic bias audit in this domain. Our findings reveal three critical insights: (1) Certain fairness metrics expose significant bias only after normalization, highlighting the impact of class imbalance. (2) Bias is significant in both service quality-related parity metrics and fraud protection-related parity metrics. (3) The fairness through unawareness approach, which involved removing sensitive attributes such as gender, does not improve bias mitigation within these datasets, likely due to the presence of correlated proxies. We also discuss socio-technical fairness-related challenges in transaction fraud models. These insights underscore the need for a nuanced approach to fairness in fraud detection, balancing protection and service quality, and moving beyond simple bias mitigation strategies. Future work must focus on refining fairness metrics and developing methods tailored to the unique complexities of the transaction fraud domain.

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of symptoms. Resting-state fMRI (rs-fMRI) captures spontaneous brain activity and functional connectivity, which are known to be disrupted in AD and mild cognitive impairment (MCI). Traditional methods, such as Pearson's correlation, have been used to calculate association matrices, but these approaches often overlook the dynamic and non-stationary nature of brain activity. In this study, we introduce a novel method that integrates discrete wavelet transform (DWT) and graph theory to model the dynamic behavior of brain networks. By decomposing rs-fMRI signals using DWT, our approach captures the time-frequency representation of brain activity, allowing for a more nuanced analysis of the underlying network dynamics. Graph theory provides a robust mathematical framework to analyze these complex networks, while machine learning is employed to automate the discrimination of different stages of AD based on learned patterns from different frequency bands. We applied our method to a dataset of rs-fMRI images from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, demonstrating its potential as an early diagnostic tool for AD and for monitoring disease progression. Our statistical analysis identifies specific brain regions and connections that are affected in AD and MCI, at different frequency bands, offering deeper insights into the disease's impact on brain function.

The performance of Quantum Autoencoders (QAEs) in anomaly detection tasks is critically dependent on the choice of data embedding and ansatz design. This study explores the effects of three data embedding techniques, data re-uploading, parallel embedding, and alternate embedding, on the representability and effectiveness of QAEs in detecting anomalies. Our findings reveal that even with relatively simple variational circuits, enhanced data embedding strategies can substantially improve anomaly detection accuracy and the representability of underlying data across different datasets. Starting with toy examples featuring low-dimensional data, we visually demonstrate the effect of different embedding techniques on the representability of the model. We then extend our analysis to complex, higher-dimensional datasets, highlighting the significant impact of embedding methods on QAE performance.