In this article, we propose a novel oversampling algorithm to increase the number of instances of minority class in an imbalanced dataset. We select two instances, Proxima and Orion, from the set of all minority class instances, based on a combination of relative distance weights and density estimation of majority class instances. Furthermore, the q-Gaussian distribution is used as a weighting mechanism to produce new synthetic instances to improve the representation and diversity. We conduct a comprehensive experiment on 42 datasets extracted from KEEL software and eight datasets from the UCI ML repository to evaluate the usefulness of the proposed (PO-QG) algorithm. Wilcoxon signed-rank test is used to compare the proposed algorithm with five other existing algorithms. The test results show that the proposed technique improves the overall classification performance. We also demonstrate the PO-QG algorithm to a dataset of Indian patients with sarcopenia.

Modern threat landscapes continue to evolve with increasing sophistication, challenging traditional detection methodologies and necessitating innovative solutions capable of addressing complex adversarial tactics. A novel framework was developed to identify ransomware activity through multimodal execution path analysis, integrating high-dimensional embeddings and dynamic heuristic derivation mechanisms to capture behavioral patterns across diverse attack variants. The approach demonstrated high adaptability, effectively mitigating obfuscation strategies and polymorphic characteristics often employed by ransomware families to evade detection. Comprehensive experimental evaluations revealed significant advancements in precision, recall, and accuracy metrics compared to baseline techniques, particularly under conditions of variable encryption speeds and obfuscated execution flows. The framework achieved scalable and computationally efficient performance, ensuring robust applicability across a range of system configurations, from resource-constrained environments to high-performance infrastructures. Notable findings included reduced false positive rates and enhanced detection latency, even for ransomware families employing sophisticated encryption mechanisms. The modular design allowed seamless integration of additional modalities, enabling extensibility and future-proofing against emerging threat vectors. Quantitative analyses further highlighted the system's energy efficiency, emphasizing its practicality for deployment in environments with stringent operational constraints. The results underline the importance of integrating advanced computational techniques and dynamic adaptability to safeguard digital ecosystems from increasingly complex threats.

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances, foundation models are still limited in their ability to encode the entire gigapixel whole-slide images without additional training and often lack complementary multimodal data. Here, we introduce Threads, a slide-level foundation model capable of generating universal representations of whole-slide images of any size. Threads was pre-trained using a multimodal learning approach on a diverse cohort of 47,171 hematoxylin and eosin (H&E)-stained tissue sections, paired with corresponding genomic and transcriptomic profiles - the largest such paired dataset to be used for foundation model development to date. This unique training paradigm enables Threads to capture the tissue's underlying molecular composition, yielding powerful representations applicable to a wide array of downstream tasks. In extensive benchmarking across 54 oncology tasks, including clinical subtyping, grading, mutation prediction, immunohistochemistry status determination, treatment response prediction, and survival prediction, Threads outperformed all baselines while demonstrating remarkable generalizability and label efficiency. It is particularly well suited for predicting rare events, further emphasizing its clinical utility. We intend to make the model publicly available for the broader community.

The integration of network information and node attribute information has recently gained significant attention in the community detection literature. In this work, we consider community detection in the Contextual Labeled Stochastic Block Model (CLSBM), where the network follows an LSBM and node attributes follow a Gaussian Mixture Model (GMM). Our primary focus is the misclassification rate, which measures the expected number of nodes misclassified by community detection algorithms. We first establish a lower bound on the optimal misclassification rate that holds for any algorithm. When we specialize our setting to the LSBM (which preserves only network information) or the GMM (which preserves only node attribute information), our lower bound recovers prior results. Moreover, we present an efficient spectral-based algorithm tailored for the CLSBM and derive an upper bound on its misclassification rate. Although the algorithm does not attain the lower bound, it serves as a reliable starting point for designing more accurate community detection algorithms (as many algorithms use spectral method as an initial step, followed by refinement procedures to enhance accuracy).

Backgrounds. Deep neural networks have demonstrated high accuracy in classifying Alzheimer's disease (AD). This study aims to enlighten the underlying black-box nature and reveal individual contributions of T1-weighted (T1w) gray-white matter texture, volumetric information and preprocessing on classification performance. Methods. We utilized T1w MRI data from the Alzheimer's Disease Neuroimaging Initiative to distinguish matched AD patients (990 MRIs) from healthy controls (990 MRIs). Preprocessing included skull stripping and binarization at varying thresholds to systematically eliminate texture information. A deep neural network was trained on these configurations, and the model performance was compared using McNemar tests with discrete Bonferroni-Holm correction. Layer-wise Relevance Propagation (LRP) and structural similarity metrics between heatmaps were applied to analyze learned features. Results. Classification performance metrics (accuracy, sensitivity, and specificity) were comparable across all configurations, indicating a negligible influence of T1w gray- and white signal texture. Models trained on binarized images demonstrated similar feature performance and relevance distributions, with volumetric features such as atrophy and skull-stripping features emerging as primary contributors. Conclusions. We revealed a previously undiscovered Clever Hans effect in a widely used AD MRI dataset. Deep neural networks classification predominantly rely on volumetric features, while eliminating gray-white matter T1w texture did not decrease the performance. This study clearly demonstrates an overestimation of the importance of gray-white matter contrasts, at least for widely used structural T1w images, and highlights potential misinterpretation of performance metrics.

Sentence embedding tasks are important in natural language processing (NLP), but improving their performance while keeping them reliable is still hard. This paper presents a framework that combines pseudo-label generation and model ensemble techniques to improve sentence embeddings. We use external data from SimpleWiki, Wikipedia, and BookCorpus to make sure the training data is consistent. The framework includes a hierarchical model with an encoding layer, refinement layer, and ensemble prediction layer, using ALBERT-xxlarge, RoBERTa-large, and DeBERTa-large models. Cross-attention layers combine external context, and data augmentation techniques like synonym replacement and back-translation increase data variety. Experimental results show large improvements in accuracy and F1-score compared to basic models, and studies confirm that cross-attention and data augmentation make a difference. This work presents an effective way to improve sentence embedding tasks and lays the groundwork for future NLP research.

This chapter is interested in the epistemology of algorithms. As I intend to approach the topic, this is an issue about epistemic justification. Current approaches to justification emphasize the transparency of algorithms, which entails elucidating their internal mechanisms -- such as functions and variables -- and demonstrating how (or that) these produce outputs. Thus, the mode of justification through transparency is contingent on what can be shown about the algorithm and, in this sense, is internal to the algorithm. In contrast, I advocate for an externalist epistemology of algorithms that I term computational reliabilism (CR). While I have previously introduced and examined CR in the field of computer simulations ([42, 53, 4]), this chapter extends this reliabilist epistemology to encompass a broader spectrum of algorithms utilized in various scientific disciplines, with a particular emphasis on machine learning applications. At its core, CR posits that an algorithm's output is justified if it is produced by a reliable algorithm. A reliable algorithm is one that has been specified, coded, used, and maintained utilizing reliability indicators. These reliability indicators stem from formal methods, algorithmic metrics, expert competencies, cultures of research, and other scientific endeavors. The primary aim of this chapter is to delineate the foundations of CR, explicate its operational mechanisms, and outline its potential as an externalist epistemology of algorithms.

Summary: This paper proposes a new algorithm that help stabilize off-policy Q-learning. The idea is to introduce approximate Bellman updates that are based on constraint actions sampled only from the support of the training data distribution. The paper shows the main source of instability is the boostrapping error. The boostrapping process might use actions that do not lie in the training data distribution. This work shows a way to mitigate this issue.

The reviewers were in consensus about the merits of this paper, in particular the value of the proposed approach and the theoretical analysis. Some concerns were raised about the experimental validation but these have been alleviated by the new results and baselines added during rebuttal. Some concerns remain regarding the clarity of the paper. The authors claim to have revised the text but we are not able to see it to validate that it has improved in this respect. The authors are strongly encouraged to put some real effort into improving the clarity of the final version.

However, these two aspects in conjunction with a non crystal clear experimental setup raise some questions.