Contextual automatic speech recognition (ASR) systems allow for recognizing out-of-vocabulary (OOV) words, such as named entities or rare words. However, it remains challenging due to limited training data and ambiguous or inconsistent pronunciations. In this paper, we propose a synthesis-driven multi-pronunciation contextual biasing method that performs zero-shot contextual ASR on a pretrained Whisper model. Specifically, we leverage text-to-speech (TTS) systems to synthesize diverse speech samples containing each target rare word, and then use the pretrained Whisper model to extract multiple predicted pronunciation variants. These variant token sequences are compiled into a prefix-trie, which assigns rewards to beam hypotheses in a shallow-fusion manner during beam-search decoding. Subsequently, any recognized variant is mapped back to the original rare word in the final transcription. The evaluation results on the LibriSpeech dataset show that our method reduces biased-word error rate (B-WER) by 43% on test-clean and 44% on test-other while maintaining unbiased-WER (U-WER) essentially unchanged.

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time consuming and prone to human error. This study proposes a deep learning framework that integrates U-Net for segmentation and a classification model to enhance diagnostic performance. The Herlev Pap Smear Dataset, a publicly available cervical cell dataset, was utilized for training and evaluation. The impact of segmentation on classification performance was evaluated by comparing the model trained on segmented images and another trained on non-segmented images. Experimental results showed that the use of segmented images marginally improved the model performance on precision (about 0.41 percent higher) and F1-score (about 1.30 percent higher), which suggests a slightly more balanced classification performance. While segmentation helps in feature extraction, the results showed that its impact on classification performance appears to be limited. The proposed framework offers a supplemental tool for clinical applications, which may aid pathologists in early diagnosis.

Out-of-distribution (OOD) detection remains challenging in text-rich networks, where textual features intertwine with topological structures. Existing methods primarily address label shifts or rudimentary domain-based splits, overlooking the intricate textual-structural diversity. For example, in social networks, where users represent nodes with textual features (name, bio) while edges indicate friendship status, OOD may stem from the distinct language patterns between bot and normal users. To address this gap, we introduce the TextTopoOOD framework for evaluating detection across diverse OOD scenarios: (1) attribute-level shifts via text augmentations and embedding perturbations; (2) structural shifts through edge rewiring and semantic connections; (3) thematically-guided label shifts; and (4) domain-based divisions. Furthermore, we propose TNT-OOD to model the complex interplay between Text aNd Topology using: 1) a novel cross-attention module to fuse local structure into node-level text representations, and 2) a HyperNetwork to generate node-specific transformation parameters. This aligns topological and semantic features of ID nodes, enhancing ID/OOD distinction across structural and textual shifts. Experiments on 11 datasets across four OOD scenarios demonstrate the nuanced challenge of TextTopoOOD for evaluating OOD detection in text-rich networks.

Unsupervised anomaly detection aims to detect defective parts of a sample by having access, during training, to a set of normal, i.e. defect-free, data. It has many applications in fields, such as industrial inspection or medical imaging, where acquiring labels is costly or when we want to avoid introducing biases in the type of anomalies that can be spotted. In this work, we propose a novel UAD method based on prototype learning and introduce a metric to compare a structured set of embeddings that balances a feature-based cost and a spatial-based cost. We leverage this metric to learn local and global prototypes with optimal transport from latent representations extracted with a pre-trained image encoder. We demonstrate that our approach can enforce a structural constraint when learning the prototypes, allowing to capture the underlying organization of the normal samples, thus improving the detection of incoherencies in images. Our model achieves performance that is on par with strong baselines on two reference benchmarks for anomaly detection on industrial images.

Matched filters are widely used to localise signal patterns due to their high efficiency and interpretability. However, their effectiveness deteriorates for low signal-to-noise ratio (SNR) signals, such as those recorded on edge devices, where prominent noise patterns can closely resemble the target within the limited length of the filter. One example is the ear-electrocardiogram (ear-ECG), where the cardiac signal is attenuated and heavily corrupted by artefacts. To address this, we propose the Sequential Matched Filter (SMF), a paradigm that replaces the conventional single matched filter with a sequence of filters designed by a Reinforcement Learning agent. By formulating filter design as a sequential decision-making process, SMF adaptively design signal-specific filter sequences that remain fully interpretable by revealing key patterns driving the decision-making. The proposed SMF framework has strong potential for reliable and interpretable clinical decision support, as demonstrated by its state-of-the-art R-peak detection and physiological state classification performance on two challenging real-world ECG datasets. The proposed formulation can also be extended to a broad range of applications that require accurate pattern localisation from noise-corrupted signals.

To reduce the amount of required labeled data for lung disease severity classification from chest X-rays (CXRs) under class imbalance, this study applied deep active learning with a Bayesian Neural Network (BNN) approximation and weighted loss function. This retrospective study collected 2,319 CXRs from 963 patients (mean age, 59.2 $\pm$ 16.6 years; 481 female) at Emory Healthcare affiliated hospitals between January and November 2020. All patients had clinically confirmed COVID-19. Each CXR was independently labeled by 3 to 6 board-certified radiologists as normal, moderate, or severe. A deep neural network with Monte Carlo Dropout was trained using active learning to classify disease severity. Various acquisition functions were used to iteratively select the most informative samples from an unlabeled pool. Performance was evaluated using accuracy, area under the receiver operating characteristic curve (AU ROC), and area under the precision-recall curve (AU PRC). Training time and acquisition time were recorded. Statistical analysis included descriptive metrics and performance comparisons across acquisition strategies. Entropy Sampling achieved 93.7% accuracy (AU ROC, 0.91) in binary classification (normal vs. diseased) using 15.4% of the training data. In the multi-class setting, Mean STD sampling achieved 70.3% accuracy (AU ROC, 0.86) using 23.1% of the labeled data. These methods outperformed more complex and computationally expensive acquisition functions and significantly reduced labeling needs. Deep active learning with BNN approximation and weighted loss effectively reduces labeled data requirements while addressing class imbalance, maintaining or exceeding diagnostic performance.

Anomaly detection in time series data is important for applications in finance, healthcare, sensor networks, and industrial monitoring. Traditional methods usually struggle with limited labeled data, high false-positive rates, and difficulty generalizing to novel anomaly types. To overcome these challenges, we propose a reinforcement learning-based framework that integrates dynamic reward shaping, Variational Autoencoder (VAE), and active learning, called DRTA. Our method uses an adaptive reward mechanism that balances exploration and exploitation by dynamically scaling the effect of VAE-based reconstruction error and classification rewards. This approach enables the agent to detect anomalies effectively in low-label systems while maintaining high precision and recall. Our experimental results on the Yahoo A1 and Yahoo A2 benchmark datasets demonstrate that the proposed method consistently outperforms state-of-the-art unsupervised and semi-supervised approaches. These findings show that our framework is a scalable and efficient solution for real-world anomaly detection tasks.

Pronunciation assessment relies on goodness of pronunciation (GOP) scores, traditionally derived from softmax-based posterior probabilities. However, posterior probabilities may suffer from overconfidence and poor phoneme separation, limiting their effectiveness. This study compares logit-based GOP scores with probability-based GOP scores for mispronunciation detection. We conducted our experiment on two L2 English speech datasets spoken by Dutch and Mandarin speakers, assessing classification performance and correlation with human ratings. Logit-based methods outperform probability-based GOP in classification, but their effectiveness depends on dataset characteristics. The maximum logit GOP shows the strongest alignment with human perception, while a combination of different GOP scores balances probability and logit features. The findings suggest that hybrid GOP methods incorporating uncertainty modeling and phoneme-specific weighting improve pronunciation assessment.

Computer-Assisted Pronunciation Training (CAPT) systems employ automatic measures of pronunciation quality, such as the goodness of pronunciation (GOP) metric. GOP relies on forced alignments, which are prone to labeling and segmentation errors due to acoustic variability. While alignment-free methods address these challenges, they are computationally expensive and scale poorly with phoneme sequence length and inventory size. To enhance efficiency, we introduce a substitution-aware alignment-free GOP that restricts phoneme substitutions based on phoneme clusters and common learner errors. We evaluated our GOP on two L2 English speech datasets, one with child speech, My Pronunciation Coach (MPC), and Spee-chOcean762, which includes child and adult speech. We compared RPS (restricted phoneme substitutions) and UPS (unrestricted phoneme substitutions) setups within alignment-free methods, which outperformed the baseline. We discuss our results and outline avenues for future research.

Speech impairments are prevalent biomarkers for Parkinson's Disease (PD), motivating the development of diagnostic techniques using speech data for clinical applications. Although deep acoustic features have shown promise for PD classification, their effectiveness often varies due to individual speaker differences, a factor that has not been thoroughly explored in the existing literature. This study investigates the effectiveness of three pre-trained audio embeddings (OpenL3, VGGish and Wav2Vec2.0 models) for PD classification. Using the NeuroVoz dataset, OpenL3 outperforms others in diadochokinesis (DDK) and listen and repeat (LR) tasks, capturing critical acoustic features for PD detection. Only Wav2Vec2.0 shows significant gender bias, achieving more favorable results for male speakers, in DDK tasks. The misclassified cases reveal challenges with atypical speech patterns, highlighting the need for improved feature extraction and model robustness in PD detection.