Associative classification is a recent and rewarding technique which integrates association rule mining and classification to a model for prediction and achieves maximum accuracy. Associative classifiers are especially fit to applications where maximum accuracy is desired to a model for prediction. There are many domains such as medical where the maximum accuracy of the model is desired. Heart disease is a single largest cause of death in developed countries and one of the main contributors to disease burden in developing countries. Mortality data from the registrar general of India shows that heart disease are a major cause of death in India, and in Andhra Pradesh coronary heart disease cause about 30%of deaths in rural areas. Hence there is a need to develop a decision support system for predicting heart disease of a patient. In this paper we propose efficient associative classification algorithm using genetic approach for heart disease prediction. The main motivation for using genetic algorithm in the discovery of high level prediction rules is that the discovered rules are highly comprehensible, having high predictive accuracy and of high interestingness values. Experimental Results show that most of the classifier rules help in the best prediction of heart disease which even helps doctors in their diagnosis decisions.

We consider the problem of sparse estimation in a factor analysis model. A traditional estimation procedure in use is the following two-step approach: the model is estimated by maximum likelihood method and then a rotation technique is utilized to find sparse factor loadings. However, the maximum likelihood estimates cannot be obtained when the number of variables is much larger than the number of observations. Furthermore, even if the maximum likelihood estimates are available, the rotation technique does not often produce a sufficiently sparse solution. In order to handle these problems, this paper introduces a penalized likelihood procedure that imposes a nonconvex penalty on the factor loadings. We show that the penalized likelihood procedure can be viewed as a generalization of the traditional two-step approach, and the proposed methodology can produce sparser solutions than the rotation technique. A new algorithm via the EM algorithm along with coordinate descent is introduced to compute the entire solution path, which permits the application to a wide variety of convex and nonconvex penalties. Monte Carlo simulations are conducted to investigate the performance of our modeling strategy. A real data example is also given to illustrate our procedure.

The concept of refinement from probability elicitation is considered for proper scoring rules. Taking directions from the axioms of probability, refinement is further clarified using a Hilbert space interpretation and reformulated into the underlying data distribution setting where connections to maximal marginal diversity and conditional entropy are considered and used to derive measures that provide arbitrarily tight bounds on the Bayes error. Refinement is also reformulated into the classifier output setting and its connections to calibrated classifiers and proper margin losses are established.

We investigate the accuracy of the two most common estimators for the maximum expected value of a general set of random variables: a generalization of the maximum sample average, and cross validation. No unbiased estimator exists and we show that it is non-trivial to select a good estimator without knowledge about the distributions of the random variables. We investigate and bound the bias and variance of the aforementioned estimators and prove consistency. The variance of cross validation can be significantly reduced, but not without risking a large bias. The bias and variance of different variants of cross validation are shown to be very problem-dependent, and a wrong choice can lead to very inaccurate estimates.

The application of machine learning to bioinformatics problems is well established. Less well understood is the application of bioinformatics techniques to machine learning and, in particular, the representation of non-biological data as biosequences. The aim of this paper is to explore the effects of giving amino acid representation to problematic machine learning data and to evaluate the benefits of supplementing traditional machine learning with bioinformatics tools and techniques. The signatures of 60 computer viruses and 60 computer worms were converted into amino acid representations and first multiply aligned separately to identify conserved regions across different families within each class (virus and worm). This was followed by a second alignment of all 120 aligned signatures together so that non-conserved regions were identified prior to input to a number of machine learning techniques. Differences in length between virus and worm signatures after the first alignment were resolved by the second alignment. Our first set of experiments indicates that representing computer malware signatures as amino acid sequences followed by alignment leads to greater classification and prediction accuracy. Our second set of experiments indicates that checking the results of data mining from artificial virus and worm data against known proteins can lead to generalizations being made from the domain of naturally occurring proteins to malware signatures. However, further work is needed to determine the advantages and disadvantages of different representations and sequence alignment methods for handling problematic machine learning data.

Link prediction is one of the fundamental problems in network analysis. In many applications, notably in genetics, a partially observed network may not contain any negative examples of absent edges, which creates a difficulty for many existing supervised learning approaches. We develop a new method which treats the observed network as a sample of the true network with different sampling rates for positive and negative examples. We obtain a relative ranking of potential links by their probabilities, utilizing information on node covariates as well as on network topology. Empirically, the method performs well under many settings, including when the observed network is sparse. We apply the method to a protein-protein interaction network and a school friendship network.

Stock markets play a fundamental role in the countries' economies, since they allow companies to raise funds for their investments in technology, expansion or infrastructure by selling stocks to the public. At the same time, stocks are, for the stockholders, important assets that can help to maintain or increase the investor's wealth for future use, like retirement, education, etc. On the other hand, stock prices are volatile and depend on several factors like companies' performances, economic activity, etc. Hence, investors and funds managers usually must constantly monitor the behavior of stock prices, in order to take correct trading decisions and to avoid excessive exposition to risky stocks. Data mining techniques have been widely proposed for stock market analysis in order to identify some patterns in price time series.

The objective of change-point detection is to discover abrupt property changes lying behind time-series data. In this paper, we present a novel statistical change-point detection algorithm based on non-parametric divergence estimation between time-series samples from two retrospective segments. Our method uses the relative Pearson divergence as a divergence measure, and it is accurately and efficiently estimated by a method of direct density-ratio estimation. Through experiments on artificial and real-world datasets including human-activity sensing, speech, and Twitter messages, we demonstrate the usefulness of the proposed method.

Although operator-valued kernels have recently received increasing interest in various machine learning and functional data analysis problems such as multi-task learning or functional regression, little attention has been paid to the understanding of their associated feature spaces. In this paper, we explore the potential of adopting an operator-valued kernel feature space perspective for the analysis of functional data. We then extend the Regularized Least Squares Classification (RLSC) algorithm to cover situations where there are multiple functions per observation. Experiments on a sound recognition problem show that the proposed method outperforms the classical RLSC algorithm.

Cascade classifiers are widely used in real-time object detection. Different from conventional classifiers that are designed for a low overall classification error rate, a classifier in each node of the cascade is required to achieve an extremely high detection rate and moderate false positive rate. Although there are a few reported methods addressing this requirement in the context of object detection, there is no principled feature selection method that explicitly takes into account this asymmetric node learning objective. We provide such an algorithm here. We show that a special case of the biased minimax probability machine has the same formulation as the linear asymmetric classifier (LAC) of Wu et al (2005). We then design a new boosting algorithm that directly optimizes the cost function of LAC. The resulting totally-corrective boosting algorithm is implemented by the column generation technique in convex optimization. Experimental results on object detection verify the effectiveness of the proposed boosting algorithm as a node classifier in cascade object detection, and show performance better than that of the current state-of-the-art.