Performance Analysis
Utility of Pancreas Surface Lobularity as a CT Biomarker for Opportunistic Screening of Type 2 Diabetes
Mathai, Tejas Sudharshan, Prasad, Anisa V., Wang, Xinya, Balamuralikrishna, Praveen T. S., Zhuang, Yan, Suri, Abhinav, Liu, Jianfei, Pickhardt, Perry J., Summers, Ronald M.
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease that affects millions of people worldwide. Early detection is crucial as it can alter pancreas function through morphological changes and increased deposition of ectopic fat, eventually leading to organ damage. While studies have shown an association between T2DM and pancreas volume and fat content, the role of increased pancreatic surface lobularity (PSL) in patients with T2DM has not been fully investigated. In this pilot work, we propose a fully automated approach to delineate the pancreas and other abdominal structures, derive CT imaging biomarkers, and opportunistically screen for T2DM. Four deep learning-based models were used to segment the pancreas in an internal dataset of 584 patients (297 males, 437 non-diabetic, age: 45$\pm$15 years). PSL was automatically detected and it was higher for diabetic patients (p=0.01) at 4.26 $\pm$ 8.32 compared to 3.19 $\pm$ 3.62 for non-diabetic patients. The PancAP model achieved the highest Dice score of 0.79 $\pm$ 0.17 and lowest ASSD error of 1.94 $\pm$ 2.63 mm (p$<$0.05). For predicting T2DM, a multivariate model trained with CT biomarkers attained 0.90 AUC, 66.7\% sensitivity, and 91.9\% specificity. Our results suggest that PSL is useful for T2DM screening and could potentially help predict the early onset of T2DM.
Rectify Evaluation Preference: Improving LLMs' Critique on Math Reasoning via Perplexity-aware Reinforcement Learning
Tian, Changyuan, Lu, Zhicong, Qian, Shuang, Liu, Nayu, Li, Peiguang, Jin, Li, Hu, Leiyi, Zeng, Zhizhao, Wang, Sirui, Zeng, Ke, Guo, Zhi
To improve Multi-step Mathematical Reasoning (MsMR) of Large Language Models (LLMs), it is crucial to obtain scalable supervision from the corpus by automatically critiquing mistakes in the reasoning process of MsMR and rendering a final verdict of the problem-solution. Most existing methods rely on crafting high-quality supervised fine-tuning demonstrations for critiquing capability enhancement and pay little attention to delving into the underlying reason for the poor critiquing performance of LLMs. In this paper, we orthogonally quantify and investigate the potential reason -- imbalanced evaluation preference, and conduct a statistical preference analysis. Motivated by the analysis of the reason, a novel perplexity-aware reinforcement learning algorithm is proposed to rectify the evaluation preference, elevating the critiquing capability. Specifically, to probe into LLMs' critiquing characteristics, a One-to-many Problem-Solution (OPS) benchmark is meticulously constructed to quantify the behavior difference of LLMs when evaluating the problem solutions generated by itself and others. Then, to investigate the behavior difference in depth, we conduct a statistical preference analysis oriented on perplexity and find an intriguing phenomenon -- ``LLMs incline to judge solutions with lower perplexity as correct'', which is dubbed as \textit{imbalanced evaluation preference}. To rectify this preference, we regard perplexity as the baton in the algorithm of Group Relative Policy Optimization, supporting the LLMs to explore trajectories that judge lower perplexity as wrong and higher perplexity as correct. Extensive experimental results on our built OPS and existing available critic benchmarks demonstrate the validity of our method.
Solvaformer: an SE(3)-equivariant graph transformer for small molecule solubility prediction
Broadbent, Jonathan, Bailey, Michael, Li, Mingxuan, Paul, Abhishek, De Lescure, Louis, Chauvin, Paul, Kogler-Anele, Lorenzo, Jangjou, Yasser, Jager, Sven
Accurate prediction of small molecule solubility using material-sparing approaches is critical for accelerating synthesis and process optimization, yet experimental measurement is costly and many learning approaches either depend on quantumderived descriptors or offer limited interpretability. We introduce Solvaformer, a geometry-aware graph transformer that models solutions as multiple molecules with independent SE(3) symmetries. The architecture combines intramolecular SE(3)-equivariant attention with intermolecular scalar attention, enabling cross-molecular communication without imposing spurious relative geometry. We train Solvaformer in a multi-task setting to predict both solubility (log S) and solvation free energy, using an alternating-batch regimen that trains on quantum-mechanical data (CombiSolv-QM) and on experimental measurements (BigSolDB 2.0). Solvaformer attains the strongest overall performance among the learned models and approaches a DFT-assisted gradient-boosting baseline, while outperforming an EquiformerV2 ablation and sequence-based alternatives. In addition, token-level attention produces chemically coherent attributions: case studies recover known intra- vs. inter-molecular hydrogen-bonding patterns that govern solubility differences in positional isomers. Taken together, Solvaformer provides an accurate, scalable, and interpretable approach to solution-phase property prediction by uniting geometric inductive bias with a mixed dataset training strategy on complementary computational and experimental data.
ProbLog4Fairness: A Neurosymbolic Approach to Modeling and Mitigating Bias
Adriaensen, Rik, Van Praet, Lucas, Bekker, Jessa, Manhaeve, Robin, Delobelle, Pieter, Buyl, Maarten
Operationalizing definitions of fairness is difficult in practice, as multiple definitions can be incompatible while each being arguably desirable. Instead, it may be easier to directly describe algorithmic bias through ad-hoc assumptions specific to a particular real-world task, e.g., based on background information on systemic biases in its context. Such assumptions can, in turn, be used to mitigate this bias during training. Y et, a framework for incorporating such assumptions that is simultaneously principled, flexible, and interpretable is currently lacking. Our approach is to formalize bias assumptions as programs in ProbLog, a probabilistic logic programming language that allows for the description of probabilistic causal relationships through logic. Neurosymbolic extensions of ProbLog then allow for easy integration of these assumptions in a neural network's training process. We propose a set of templates to express different types of bias and show the versatility of our approach on synthetic tabular datasets with known biases. Using estimates of the bias distortions present, we also succeed in mitigating algorithmic bias in real-world tabular and image data. We conclude that ProbLog4Fairness outperforms baselines due to its ability to flexibly model the relevant bias assumptions, where other methods typically uphold a fixed bias type or notion of fairness.
Enhancing Password Security Through a High-Accuracy Scoring Framework Using Random Forests
Mazelan, Muhammed El Mustaqeem, Abdul, Noor Hazlina, AlDahoul, Nouar
Password security plays a crucial role in cybersecurity, yet traditional password strength meters, which rely on static rules like character - type requirements, often fail . Such methods are easily bypassed by common password patterns (e.g., 'P@ssw0rd1!'), giving users a false sense of security . To address this, we implement and evaluate a password strength scoring system by comparing four machine learning models: Random Forest (RF), Support Vector Machine (SVM), a Convolutional Neural Network (CNN), and Logistic Regression with a dataset of over 660,000 real - world passwords. Our primary contribution is a novel hybrid feature engineering approach that captures nuanced vulnerabilities missed by standard metrics . We introduce features like leetspeak - normalized Shannon entropy to assess true randomness, pattern detection for keyboard walks and sequences, and character - level TF - IDF n - grams to identify frequently reused substrings from breached password datasets. Crucially, the interpretability of the Random Forest model allows for feature importance analysis, providing a clear pathway to developing security tools that offer specific, actionable feedback to users. This study bridges the gap betwee n predictive accuracy and practical usability, resulting in a high - performance scoring system that not only reduces password - based vulnerabilities but also empowers users to make more informed security decisions. Keywords - Password Security, Machine Learning, Rule - Based Attack, Brute - Force Attack, Dictionary Attack, Cybersecurity. 1. P asswords remain a cornerstone of online security, serving as the primary means of authentication for countless systems and applications . However, this reliance is a critical vulnerability; according to a report by Google Cloud, a staggering 86% of breaches involve stolen credentials, posing a significant threat to both user data and system security .[1] M any users choose weak, easily guessable passwords, which pose a serious threat to both user data and system security . Attackers frequently exploit this vulnerability in large - scale attacks, compromising user privacy and enabling financial fraud . Most traditional password strength scoring tools rely on static rules, such as requiring a mix of lowercase, uppercase, digits, and special characters (LUDS), which fail to adapt to evolving attack patterns .
WaterMod: Modular Token-Rank Partitioning for Probability-Balanced LLM Watermarking
Park, Shinwoo, Park, Hyejin, Ahn, Hyeseon, Han, Yo-Sub
Large language models now draft news, legal analyses, and software code with human-level fluency. At the same time, regulations such as the EU AI Act mandate that each synthetic passage carry an imperceptible, machine-verifiable mark for provenance. Conventional logit-based watermarks satisfy this requirement by selecting a pseudorandom green vocabulary at every decoding step and boosting its logits, yet the random split can exclude the highest-probability token and thus erode fluency. WaterMod mitigates this limitation through a probability-aware modular rule. The vocabulary is first sorted in descending model probability; the resulting ranks are then partitioned by the residue rank mod k, which distributes adjacent-and therefore semantically similar-tokens across different classes. A fixed bias of small magnitude is applied to one selected class. In the zero-bit setting (k=2), an entropy-adaptive gate selects either the even or the odd parity as the green list. Because the top two ranks fall into different parities, this choice embeds a detectable signal while guaranteeing that at least one high-probability token remains available for sampling. In the multi-bit regime (k>2), the current payload digit d selects the color class whose ranks satisfy rank mod k = d. Biasing the logits of that class embeds exactly one base-k digit per decoding step, thereby enabling fine-grained provenance tracing. The same modular arithmetic therefore supports both binary attribution and rich payloads. Experimental results demonstrate that WaterMod consistently attains strong watermark detection performance while maintaining generation quality in both zero-bit and multi-bit settings. This robustness holds across a range of tasks, including natural language generation, mathematical reasoning, and code synthesis. Our code and data are available at https://github.com/Shinwoo-Park/WaterMod.
Can Current Detectors Catch Face-to-Voice Deepfake Attacks?
Nguyen, Nguyen Linh Bao, Abuadbba, Alsharif, Moore, Kristen, Wu, Tingmin
The rapid advancement of generative models has enabled the creation of increasingly stealthy synthetic voices, commonly referred to as audio deepfakes. A recent technique, FOICE [USENIX'24], demonstrates a particularly alarming capability: generating a victim's voice from a single facial image, without requiring any voice sample. By exploiting correlations between facial and vocal features, FOICE produces synthetic voices realistic enough to bypass industry-standard authentication systems, including WeChat Voiceprint and Microsoft Azure. This raises serious security concerns, as facial images are far easier for adversaries to obtain than voice samples, dramatically lowering the barrier to large-scale attacks. In this work, we investigate two core research questions: (RQ1) can state-of-the-art audio deepfake detectors reliably detect FOICE-generated speech under clean and noisy conditions, and (RQ2) whether fine-tuning these detectors on FOICE data improves detection without overfitting, thereby preserving robustness to unseen voice generators such as SpeechT5. Our study makes three contributions. First, we present the first systematic evaluation of FOICE detection, showing that leading detectors consistently fail under both standard and noisy conditions. Second, we introduce targeted fine-tuning strategies that capture FOICE-specific artifacts, yielding significant accuracy improvements. Third, we assess generalization after fine-tuning, revealing trade-offs between specialization to FOICE and robustness to unseen synthesis pipelines. These findings expose fundamental weaknesses in today's defenses and motivate new architectures and training protocols for next-generation audio deepfake detection.
Quantifying Climate Policy Action and Its Links to Development Outcomes: A Cross-National Data-Driven Analysis
Addressing climate change effectively requires more than cataloguing the number of policies in place; it calls for tools that can reveal their thematic priorities and their tangible impacts on development outcomes. Existing assessments often rely on qualitative descriptions or composite indices, which can mask crucial differences between key domains such as mitigation, adaptation, disaster risk management, and loss and damage. To bridge this gap, we develop a quantitative indicator of climate policy orientation by applying a multilingual transformer-based language model to official national policy documents, achieving a classification accuracy of 0.90 (F1-score). Linking these indicators with World Bank development data in panel regressions reveals that mitigation policies are associated with higher GDP and GNI; disaster risk management correlates with greater GNI and debt but reduced foreign direct investment; adaptation and loss and damage show limited measurable effects. This integrated NLP-econometric framework enables comparable, theme-specific analysis of climate governance, offering a scalable method to monitor progress, evaluate trade-offs, and align policy emphasis with development goals.
Backdoor Attacks Against Speech Language Models
Fortier, Alexandrine, Thebaud, Thomas, Villalba, Jesús, Dehak, Najim, Cardinal, Patrick
Large Language Models (LLMs) and their multimodal extensions are becoming increasingly popular. One common approach to enable multimodality is to cascade domain-specific encoders with an LLM, making the resulting model inherit vulnerabilities from all of its components. In this work, we present the first systematic study of audio backdoor attacks against speech language models. We demonstrate its effectiveness across four speech encoders and three datasets, covering four tasks: automatic speech recognition (ASR), speech emotion recognition, and gender and age prediction. The attack consistently achieves high success rates, ranging from 90.76% to 99.41%. To better understand how backdoors propagate, we conduct a component-wise analysis to identify the most vulnerable stages of the pipeline. Finally, we propose a fine-tuning-based defense that mitigates the threat of poisoned pretrained encoders. Large language models (LLMs) are increasingly extended to multimodal settings, processing combinations of text, images, video, and audio (DeepMind, 2023; Biadsy et al., 2023; Radford et al., 2021; Rajaa & Tushar, 2024). While powerful, these systems inherit vulnerabilities from each of their components. Among them are backdoor attacks, in which a model behaves normally on clean inputs but produces targeted outputs when a hidden trigger is present (Gu et al., 2017). Prior backdoor studies have largely focused on single-modality large language models (Xu et al., 2023; Y ao et al., 2024) or speech processing models (Zhai et al., 2021; Koffas et al., 2022), leaving open questions about how such attacks propagate in a cascaded speech language model.
Interpretable Clinical Classification with Kolgomorov-Arnold Networks
Almodóvar, Alejandro, Apellániz, Patricia A., Garrido, Alba, Fernández-Salvador, Fernando, Zazo, Santiago, Parras, Juan
Why should a clinician trust an Artificial Intelligence (AI) prediction? Despite the increasing accuracy of machine learning methods in medicine, the lack of transparency continues to hinder their adoption in clinical practice. In this work, we explore Kolmogorov-Arnold Networks (KANs) for clinical classification tasks on tabular data. In contrast to traditional neural networks, KANs are function-based architectures that offer intrinsic interpretability through transparent, symbolic representations. We introduce \emph{Logistic-KAN}, a flexible generalization of logistic regression, and \emph{Kolmogorov-Arnold Additive Model (KAAM)}, a simplified additive variant that delivers transparent, symbolic formulas. Unlike ``black-box'' models that require post-hoc explainability tools, our models support built-in patient-level insights, intuitive visualizations, and nearest-patient retrieval. Across multiple health datasets, our models match or outperform standard baselines, while remaining fully interpretable. These results position KANs as a promising step toward trustworthy AI that clinicians can understand, audit, and act upon. We release the code for reproducibility in \codeurl.