Ovarian cancer (OC) is one of the most prevalent types of cancer in women. Early and accurate diagnosis is crucial for the survival of the patients. However, the majority of women are diagnosed in advanced stages due to the lack of effective biomarkers and accurate screening tools. While previous studies sought a common biomarker, our study suggests different biomarkers for the premenopausal and postmenopausal populations. This can provide a new perspective in the search for novel predictors for the effective diagnosis of OC. Lack of explainability is one major limitation of current AI systems. The stochastic nature of the ML algorithms raises concerns about the reliability of the system as it is difficult to interpret the reasons behind the decisions. To increase the trustworthiness and accountability of the diagnostic system as well as to provide transparency and explanations behind the predictions, explainable AI has been incorporated into the ML framework. SHAP is employed to quantify the contributions of the selected biomarkers and determine the most discriminative features. A hybrid decision support system has been established that can eliminate the bottlenecks caused by the black-box nature of the ML algorithms providing a safe and trustworthy AI tool. The diagnostic accuracy obtained from the proposed system outperforms the existing methods as well as the state-of-the-art ROMA algorithm by a substantial margin which signifies its potential to be an effective tool in the differential diagnosis of OC.

Investors are interested in predicting future success of startup companies, preferably using publicly available data which can be gathered using free online sources. Using public-only data has been shown to work, but there is still much room for improvement. Two of the best performing prediction experiments use 17 and 49 features respectively, mostly numeric and categorical in nature. In this paper, we significantly expand and diversify both the sources and the number of features (to 171) to achieve better prediction. Data collected from Crunchbase, the Google Search API, and Twitter (now X) are used to predict whether a company will raise a round of funding within a fixed time horizon. Much of the new features are textual and the Twitter subset include linguistic metrics such as measures of passive voice and parts-of-speech. A total of ten machine learning models are also evaluated for best performance. The adaptable model can be used to predict funding 1-5 years into the future, with a variable cutoff threshold to favor either precision or recall. Prediction with comparable assumptions generally achieves F scores above 0.730 which outperforms previous attempts in the literature (0.531), and does so with fewer examples. Furthermore, we find that the vast majority of the performance impact comes from the top 18 of 171 features which are mostly generic company observations, including the best performing individual feature which is the free-form text description of the company.

Abstract--Medical Vision Language Pretraining (VLP) has recently emerged as a promising solution to the scarcity of labeled data in the medical domain. By leveraging paired/unpaired vision and text datasets through self-supervised learning, models can be trained to acquire vast knowledge and learn robust feature representations. Such pretrained models have the potential to enhance multiple downstream medical tasks simultaneously, reducing the dependency on labeled data. However, despite recent progress and its potential, there is no such comprehensive survey paper that has explored the various aspects and advancements in medical VLP. In this paper, we specifically review existing works through the lens of different pretraining objectives, architectures, downstream evaluation tasks, and datasets utilized for pretraining and downstream tasks. Subsequently, we delve into current challenges in medical VLP, discussing existing and potential solutions, and conclude by highlighting future directions. To the best of our knowledge, this is the first survey focused on medical VLP. Data-driven artificial intelligence (AI) has undergone rapid advancement in recent years, bringing transformative changes to various domains, including computer vision and natural language processing [1]-[5]. The availability of large-scale Figure 1: Various aspects of Medical Vision Language Pretraining data has played a pivotal role in driving this progress. With (VLP) discussed in this paper. AI is no longer confined to single-modality systems; instead, these multimodal datasets can play a crucial role in training there has been a notable shift towards multimodal learning [6]- large-scale, generalized AI models. Similar trends are quickly emerging, even within the In recent years, self-supervised learning has become a medical domain [10]-[13]. There is a particular emphasis on Often, medical experts rely on information from multiple vision-language models in both the general domain [9], [20], modalities for diagnostic decision-making. For instance, [21] and the medical domain [22]-[27], given that vision physicians consider various factors, including medical images, and language are two key data modalities. By employing blood test results, and sensor data, to recommend treatments.

As artificial intelligence (AI) rapidly approaches human-level performance in medical imaging, it is crucial that it does not exacerbate or propagate healthcare disparities. Prior research has established AI's capacity to infer demographic data from chest X-rays, leading to a key concern: do models using demographic shortcuts have unfair predictions across subpopulations? In this study, we conduct a thorough investigation into the extent to which medical AI utilizes demographic encodings, focusing on potential fairness discrepancies within both in-distribution training sets and external test sets. Our analysis covers three key medical imaging disciplines: radiology, dermatology, and ophthalmology, and incorporates data from six global chest X-ray datasets. We confirm that medical imaging AI leverages demographic shortcuts in disease classification. While correcting shortcuts algorithmically effectively addresses fairness gaps to create "locally optimal" models within the original data distribution, this optimality is not true in new test settings. Surprisingly, we find that models with less encoding of demographic attributes are often most "globally optimal", exhibiting better fairness during model evaluation in new test environments. Our work establishes best practices for medical imaging models which maintain their performance and fairness in deployments beyond their initial training contexts, underscoring critical considerations for AI clinical deployments across populations and sites.

Graph Lottery Tickets (GLTs), comprising a sparse adjacency matrix and a sparse graph neural network (GNN), can significantly reduce the inference latency and compute footprint compared to their dense counterparts. Despite these benefits, their performance against adversarial structure perturbations remains to be fully explored. In this work, we first investigate the resilience of GLTs against different structure perturbation attacks and observe that they are highly vulnerable and show a large drop in classification accuracy. Based on this observation, we then present an adversarially robust graph sparsification (ARGS) framework that prunes the adjacency matrix and the GNN weights by optimizing a novel loss function capturing the graph homophily property and information associated with both the true labels of the train nodes and the pseudo labels of the test nodes. By iteratively applying ARGS to prune both the perturbed graph adjacency matrix and the GNN model weights, we can find adversarially robust graph lottery tickets that are highly sparse yet achieve competitive performance under different untargeted training-time structure attacks. Evaluations conducted on various benchmarks, considering different poisoning structure attacks, namely, PGD, MetaAttack, Meta-PGD, and PR-BCD demonstrate that the GLTs generated by ARGS can significantly improve the robustness, even when subjected to high levels of sparsity.

Trajectory recovery based on the snapshots from the city-wide multi-camera network facilitates urban mobility sensing and driveway optimization. The state-of-the-art solutions devoted to such a vision-based scheme typically incorporate predefined rules or unsupervised iterative feedback, struggling with multi-fold challenges such as lack of open-source datasets for training the whole pipeline, and the vulnerability to the noises from visual inputs. In response to the dilemma, this paper proposes VisionTraj, the first learning-based model that reconstructs vehicle trajectories from snapshots recorded by road network cameras. Coupled with it, we elaborate on two rational vision-trajectory datasets, which produce extensive trajectory data along with corresponding visual snapshots, enabling supervised vision-trajectory interplay extraction. Following the data creation, based on the results from the off-the-shelf multi-modal vehicle clustering, we first re-formulate the trajectory recovery problem as a generative task and introduce the canonical Transformer as the autoregressive backbone. Then, to identify clustering noises (e.g., false positives) with the bound on the snapshots' spatiotemporal dependencies, a GCN-based soft-denoising module is conducted based on the fine- and coarse-grained Re-ID clusters. Additionally, we harness strong semantic information extracted from the tracklet to provide detailed insights into the vehicle's entry and exit actions during trajectory recovery. The denoising and tracklet components can also act as plug-and-play modules to boost baselines. Experimental results on the two hand-crafted datasets show that the proposed VisionTraj achieves a maximum +11.5% improvement against the sub-best model.

In real-world scenarios, human actions often fall outside the distribution of training data, making it crucial for models to recognize known actions and reject unknown ones. However, using pure skeleton data in such open-set conditions poses challenges due to the lack of visual background cues and the distinct sparse structure of body pose sequences. In this paper, we tackle the unexplored Open-Set Skeleton-based Action Recognition (OS-SAR) task and formalize the benchmark on three skeleton-based datasets. We assess the performance of seven established open-set approaches on our task and identify their limits and critical generalization issues when dealing with skeleton information. To address these challenges, we propose a distance-based cross-modality ensemble method that leverages the cross-modal alignment of skeleton joints, bones, and velocities to achieve superior open-set recognition performance. We refer to the key idea as CrossMax - an approach that utilizes a novel cross-modality mean max discrepancy suppression mechanism to align latent spaces during training and a cross-modality distance-based logits refinement method during testing. CrossMax outperforms existing approaches and consistently yields state-of-the-art results across all datasets and backbones. The benchmark, code, and models will be released at https://github.com/KPeng9510/OS-SAR.

Modern Code Review (MCR) is an informal tool-assisted quality assurance practice. It relies on the asynchronous communication among the authors of code changes and reviewers, who are developers that provide feedback. However, from candidate developers, some are able to provide better feedback than others given a particular context. The selection of reviewers is thus an important task, which can benefit from automated support. Many approaches have been proposed in this direction, using for example data from code review repositories to recommend reviewers. In this paper, we propose the use of team-related features to improve the performance of predictions that are helpful to build code reviewer recommenders, with our target predictions being the identification of reviewers that would participate in a review and the provided amount of feedback. We evaluate the prediction power of these features, which are related to code ownership, workload, and team relationship. This evaluation was done by carefully addressing challenges imposed by the MCR domain, such as temporal aspects of the dataset and unbalanced classes. Moreover, given that it is currently unknown how much past data is needed for building MCR prediction models with acceptable performance, we explore the amount of past data used to build prediction models. Our results show that, individually, features related to code ownership have the best prediction power. However, based on feature selection, we conclude that all proposed features together with lines of code can make the best predictions for both reviewer participation and amount of feedback. Regarding the amount of past data, the timeframes of 3, 6, 9, and 12 months of data produce similar results. Therefore, models can be trained considering short timeframes, thus reducing the computational costs with negligible impact in the prediction performance ...

There is no denying that the use of Information Technology (IT) is undergoing exponential growth in today's world. This digital transformation has also given rise to a multitude of security challenges, notably in the realm of cybercrime. In response to these growing threats, public and private sectors have prioritized the strengthening of IT security measures. In light of the growing security concern, Artificial Intelligence (AI) has gained prominence within the cybersecurity landscape. This paper presents a comprehensive survey of recent advancements in AI-driven threat response systems. To the best of our knowledge, the most recent survey covering the AI reaction domain was conducted in 2017. Since then, considerable literature has been published and therefore it is worth reviewing it. By means of several shared features, each of the studies is compared on a common ground. Through an analysis of the research papers conducted on a standardized basis, this survey aims to unravel the complexities and opportunities of integrating AI into cyber defense. The conclusions drawn from this collective analysis provide a comprehensive snapshot of the evolving landscape at the intersection of AI and cybersecurity. This landscape underscores the growing significance of not only anticipating and detecting threats but also responding to them effectively. Additionally, from these reviews, various research challenges for the future are presented. These challenges serve as a roadmap for researchers and practitioners in the field of AI-integrated reactive strategies.

The rapid development of graph neural networks (GNNs) encourages the rising of link prediction, achieving promising performance with various applications. Unfortunately, through a comprehensive analysis, we surprisingly find that current link predictors with dynamic negative samplers (DNSs) suffer from the migration phenomenon between "easy" and "hard" samples, which goes against the preference of DNS of choosing "hard" negatives, thus severely hindering capability. Towards this end, we propose the MeBNS framework, serving as a general plugin that can potentially improve current negative sampling based link predictors. In particular, we elaborately devise a Meta-learning Supported Teacher-student GNN (MST-GNN) that is not only built upon teacher-student architecture for alleviating the migration between "easy" and "hard" samples but also equipped with a meta learning based sample re-weighting module for helping the student GNN distinguish "hard" samples in a fine-grained manner. To effectively guide the learning of MST-GNN, we prepare a Structure enhanced Training Data Generator (STD-Generator) and an Uncertainty based Meta Data Collector (UMD-Collector) for supporting the teacher and student GNN, respectively. Extensive experiments show that the MeBNS achieves remarkable performance across six link prediction benchmark datasets.