Recent research has demonstrated the capability of physiological signals to infer both user emotional and attention responses. This presents an opportunity for leveraging widely available physiological sensors in smartwatches, to detect real-time emotional cues in users, such as stress and excitement. In this paper, we introduce SensEmo, a smartwatch-based system designed for affective learning. SensEmo utilizes multiple physiological sensor data, including heart rate and galvanic skin response, to recognize a student's motivation and concentration levels during class. This recognition is facilitated by a personalized emotion recognition model that predicts emotional states based on degrees of valence and arousal. With real-time emotion and attention feedback from students, we design a Markov decision process-based algorithm to enhance student learning effectiveness and experience by by offering suggestions to the teacher regarding teaching content and pacing. We evaluate SensEmo with 22 participants in real-world classroom environments. Evaluation results show that SensEmo recognizes student emotion with an average of 88.9% accuracy. More importantly, SensEmo assists students to achieve better online learning outcomes, e.g., an average of 40.0% higher grades in quizzes, over the traditional learning without student emotional feedback.

Choosing a meaningful subset of features from high-dimensional observations in unsupervised settings can greatly enhance the accuracy of downstream analysis, such as clustering or dimensionality reduction, and provide valuable insights into the sources of heterogeneity in a given dataset. In this paper, we propose a self-supervised graph-based approach for unsupervised feature selection. Our method's core involves computing robust pseudo-labels by applying simple processing steps to the graph Laplacian's eigenvectors. The subset of eigenvectors used for computing pseudo-labels is chosen based on a model stability criterion. We then measure the importance of each feature by training a surrogate model to predict the pseudo-labels from the observations. Our approach is shown to be robust to challenging scenarios, such as the presence of outliers and complex substructures. We demonstrate the effectiveness of our method through experiments on real-world datasets, showing its robustness across multiple domains, particularly its effectiveness on biological datasets.

Perception systems, especially cameras, are the eyes of automated driving systems. Ensuring that they function reliably and robustly is therefore an important building block in the automation of vehicles. There are various approaches to test the perception of automated driving systems. Ultimately, however, it always comes down to the investigation of the behavior of perception systems under specific input data. Camera images are a crucial part of the input data. Image data sets are therefore collected for the testing of automated driving systems, but it is non-trivial to find specific images in these data sets. Thanks to recent developments in neural networks, there are now methods for sorting the images in a data set according to their similarity to a prompt in natural language. In order to further automate the provision of search results, we make a contribution by automating the threshold definition in these sorted results and returning only the images relevant to the prompt as a result. Our focus is on preventing false positives and false negatives equally. It is also important that our method is robust and in the case that our assumptions are not fulfilled, we provide a fallback solution.

Recently, therapeutic peptides have demonstrated great promise for cancer treatment. To explore powerful anticancer peptides, artificial intelligence (AI)-based approaches have been developed to systematically screen potential candidates. However, the lack of efficient featurization of peptides has become a bottleneck for these machine-learning models. In this paper, we propose a topology-enhanced machine learning model (Top-ML) for anticancer peptide prediction. Our Top-ML employs peptide topological features derived from its sequence "connection" information characterized by vector and spectral descriptors. Our Top-ML model has been validated on two widely used AntiCP 2.0 benchmark datasets and has achieved state-of-the-art performance. Our results highlight the potential of leveraging novel topology-based featurization to accelerate the identification of anticancer peptides.

The primary objective of methods in continual learning is to learn tasks in a sequential manner over time from a stream of data, while mitigating the detrimental phenomenon of catastrophic forgetting. In this paper, we focus on learning an optimal representation between previous class prototypes and newly encountered ones. We propose a prototypical network with a Bayesian learning-driven contrastive loss (BLCL) tailored specifically for class-incremental learning scenarios. Therefore, we introduce a contrastive loss that incorporates new classes into the latent representation by reducing the intra-class distance and increasing the inter-class distance. Our approach dynamically adapts the balance between the cross-entropy and contrastive loss functions with a Bayesian learning technique. Empirical evaluations conducted on both the CIFAR-10 and CIFAR-100 dataset for image classification and images of a GNSS-based dataset for interference classification validate the efficacy of our method, showcasing its superiority over existing state-of-the-art approaches.

This paper investigates neuron dropout as a post-processing bias mitigation for deep neural networks (DNNs). Neural-driven software solutions are increasingly applied in socially critical domains with significant fairness implications. While neural networks are exceptionally good at finding statistical patterns from data, they may encode and amplify existing biases from the historical data. Existing bias mitigation algorithms often require modifying the input dataset or the learning algorithms. We posit that the prevalent dropout methods that prevent over-fitting during training by randomly dropping neurons may be an effective and less intrusive approach to improve the fairness of pre-trained DNNs. However, finding the ideal set of neurons to drop is a combinatorial problem. We propose NeuFair, a family of post-processing randomized algorithms that mitigate unfairness in pre-trained DNNs via dropouts during inference after training. Our randomized search is guided by an objective to minimize discrimination while maintaining the model's utility. We show that our design of randomized algorithms is effective and efficient in improving fairness (up to 69%) with minimal or no model performance degradation. We provide intuitive explanations of these phenomena and carefully examine the influence of various hyperparameters of search algorithms on the results. Finally, we empirically and conceptually compare NeuFair to different state-of-the-art bias mitigators.

This paper presents a novel and comprehensive solution to enhance both the robustness and efficiency of question answering (QA) systems through supervised contrastive learning (SCL). Training a high-performance QA system has become straightforward with pre-trained language models, requiring only a small amount of data and simple fine-tuning. However, despite recent advances, existing QA systems still exhibit significant deficiencies in functionality and training efficiency. We address the functionality issue by defining four key tasks: user input intent classification, out-of-domain input detection, new intent discovery, and continual learning. We then leverage a unified SCL-based representation learning method to efficiently build an intra-class compact and inter-class scattered feature space, facilitating both known intent classification and unknown intent detection and discovery. Consequently, with minimal additional tuning on downstream tasks, our approach significantly improves model efficiency and achieves new state-of-the-art performance across all tasks.

This study introduces a new approach to addressing positive and unlabeled (PU) data through the double exponential tilting model (DETM). Traditional methods often fall short because they only apply to selected completely at random (SCAR) PU data, where the labeled positive and unlabeled positive data are assumed to be from the same distribution. In contrast, our DETM's dual structure effectively accommodates the more complex and underexplored selected at random PU data, where the labeled and unlabeled positive data can be from different distributions. We rigorously establish the theoretical foundations of DETM, including identifiability, parameter estimation, and asymptotic properties. Additionally, we move forward to statistical inference by developing a goodness-of-fit test for the SCAR condition and constructing confidence intervals for the proportion of positive instances in the target domain. We leverage an approximated Bayes classifier for classification tasks, demonstrating DETM's robust performance in prediction. Through theoretical insights and practical applications, this study highlights DETM as a comprehensive framework for addressing the challenges of PU data.

Foundation models, e.g., large language models (LLMs), trained on internet-scale data possess zero-shot generalization capabilities that make them a promising technology towards detecting and mitigating out-of-distribution failure modes of robotic systems. Fully realizing this promise, however, poses two challenges: (i) mitigating the considerable computational expense of these models such that they may be applied online, and (ii) incorporating their judgement regarding potential anomalies into a safe control framework. In this work, we present a two-stage reasoning framework: First is a fast binary anomaly classifier that analyzes observations in an LLM embedding space, which may then trigger a slower fallback selection stage that utilizes the reasoning capabilities of generative LLMs. These stages correspond to branch points in a model predictive control strategy that maintains the joint feasibility of continuing along various fallback plans to account for the slow reasoner's latency as soon as an anomaly is detected, thus ensuring safety. We show that our fast anomaly classifier outperforms autoregressive reasoning with state-of-the-art GPT models, even when instantiated with relatively small language models. This enables our runtime monitor to improve the trustworthiness of dynamic robotic systems, such as quadrotors or autonomous vehicles, under resource and time constraints. Videos illustrating our approach in both simulation and real-world experiments are available on this project page: https://sites.google.com/view/aesop-llm.

Pathogenic chromosome abnormalities are very common among the general population. While numerical chromosome abnormalities can be quickly and precisely detected, structural chromosome abnormalities are far more complex and typically require considerable efforts by human experts for identification. This paper focuses on investigating the modeling of chromosome features and the identification of chromosomes with structural abnormalities. Most existing data-driven methods concentrate on a single chromosome and consider each chromosome independently, overlooking the crucial aspect of homologous chromosomes. In normal cases, homologous chromosomes share identical structures, with the exception that one of them is abnormal. Therefore, we propose an adaptive method to align homologous chromosomes and diagnose structural abnormalities through homologous similarity. Inspired by the process of human expert diagnosis, we incorporate information from multiple pairs of homologous chromosomes simultaneously, aiming to reduce noise disturbance and improve prediction performance. Extensive experiments on real-world datasets validate the effectiveness of our model compared to baselines.