A binary decision task, like yes-no questions or answer verification, reflects a significant real-world scenario such as where users look for confirmation about the correctness of their decisions on specific issues. In this work, we observe that language models exhibit a negative bias in the binary decisions of complex reasoning tasks. Based on our observations and the rationale about attention-based model dynamics, we propose a negative attention score (NAS) to systematically and quantitatively formulate negative bias. Based on NAS, we identify attention heads that attend to negative tokens provided in the instructions as answer candidate of binary decisions, regardless of the question in the prompt, and validate their association with the negative bias. Additionally, we propose the negative attention score alignment (NASA) method, which is a parameter-efficient fine-tuning technique to address the extracted negatively biased attention heads. Experimental results from various domains of reasoning tasks and large model search space demonstrate that NASA significantly reduces the gap between precision and recall caused by negative bias while preserving their generalization abilities. Our codes are available at \url{https://github.com/ysw1021/NASA}.

Ontologies are formal representations of knowledge in specific domains that provide a structured framework for organizing and understanding complex information. Creating ontologies, however, is a complex and time-consuming endeavor. ChEBI is a well-known ontology in the field of chemistry, which provides a comprehensive resource for defining chemical entities and their properties. However, it covers only a small fraction of the rapidly growing knowledge in chemistry and does not provide references to the scientific literature. To address this, we propose a methodology that involves augmenting existing annotated text corpora with knowledge from Chebi and fine-tuning a large language model (LLM) to recognize chemical entities and their roles in scientific text. Our experiments demonstrate the effectiveness of our approach. By combining ontological knowledge and the language understanding capabilities of LLMs, we achieve high precision and recall rates in identifying both the chemical entities and roles in scientific literature. Furthermore, we extract them from a set of 8,000 ChemRxiv articles, and apply a second LLM to create a knowledge graph (KG) of chemical entities and roles (CEAR), which provides complementary information to ChEBI, and can help to extend it.

However, the availability of skilled medical personnel in austere environments is often limited. Autonomous robotic ultrasound systems can aid in needle insertion for medication delivery and support non-experts in such tasks. Despite advances in autonomous needle insertion, inaccuracies in vessel segmentation predictions pose risks. Understanding the uncertainty of predictive models in ultrasound imaging is crucial for assessing their reliability. We introduce MSU-Net, a novel multistage approach for training an ensemble of U-Nets to yield accurate ultrasound image segmentation maps. We demonstrate substantial improvements, 18.1% over a single Monte Carlo U-Net, enhancing uncertainty evaluations, model transparency, and trustworthiness. By highlighting areas of model certainty, MSU-Net can guide safe needle insertions, empowering non-experts to accomplish such tasks.

Static noise maps depicting long-term noise levels over wide areas are valuable urban planning assets for municipalities in decreasing noise exposure of residents. However, non-traffic noise sources with transient behavior, which people complain frequently, are usually ignored by static maps. We propose here a dynamic noise mapping approach using the data collected via low-power wide-area network (LPWAN, specifically LoRaWAN) based internet of things (IoT) infrastructure, which is one of the most common communication backbones for smart cities. Noise mapping based on LPWAN is challenging due to the low data rates of these protocols. The proposed dynamic noise mapping approach diminishes the negative implications of data rate limitations using machine learning (ML) for event and location prediction of non-traffic sources based on the scarce data. The strength of these models lies in their consideration of the spatial variance in acoustic behavior caused by the buildings in urban settings. The effectiveness of the proposed method and the accuracy of the resulting dynamic maps are evaluated in field tests. The results show that the proposed system can decrease the map error caused by non-traffic sources up to 51% and can stay effective under significant packet losses.

Objectives: This study aims to assess the impact of domain shift on chest X-ray classification accuracy and to analyze the influence of ground truth label quality and demographic factors such as age group, sex, and study year. Materials and Methods: We used a DenseNet121 model pretrained MIMIC-CXR dataset for deep learning-based multilabel classification using ground truth labels from radiology reports extracted using the CheXpert and CheXbert Labeler. We compared the performance of the 14 chest X-ray labels on the MIMIC-CXR and Veterans Healthcare Administration chest X-ray dataset (VA-CXR). The VA-CXR dataset comprises over 259k chest X-ray images spanning between the years 2010 and 2022. Results: The validation of ground truth and the assessment of multi-label classification performance across various NLP extraction tools revealed that the VA-CXR dataset exhibited lower disagreement rates than the MIMIC-CXR datasets. Additionally, there were notable differences in AUC scores between models utilizing CheXpert and CheXbert. When evaluating multi-label classification performance across different datasets, minimal domain shift was observed in unseen datasets, except for the label "Enlarged Cardiomediastinum." The study year's subgroup analyses exhibited the most significant variations in multi-label classification model performance. These findings underscore the importance of considering domain shifts in chest X-ray classification tasks, particularly concerning study years. Conclusion: Our study reveals the significant impact of domain shift and demographic factors on chest X-ray classification, emphasizing the need for improved transfer learning and equitable model development. Addressing these challenges is crucial for advancing medical imaging and enhancing patient care.

We focus this analysis on the United States' Department of Defense (DoD), where the US Army alone is projected to spend an estimated $5 billion per year (in 2020 dollar terms through 2050), developing and acquiring ground vehicles, where ground vehicles are any vehicles other than aircraft and ships (CBO 2021). Maintaining this enormous investment is critical to ensuring combat readiness across the DoD, where the department spent $90 billion in 2022 on maintaining vehicles across domains: ground, air, and sea (GAO 2022). Predicting requirements is critical to an effective maintenance program. The application of statistics towards vehicle maintenance prediction is often referred to as predictive maintenance. Recognizing the importance of predictive maintenance, in the 2022 National Defense Authorization Act (NDAA) Congress required the DoD Inspector General Office to review predictive maintenance practices, originally established by DoD directives in 2002 and 2007 (DoDIG 2023).

While large language models (LLMs) are extensively used, there are raising concerns regarding privacy, security, and copyright due to their opaque training data, which brings the problem of detecting pre-training data on the table. Current solutions to this problem leverage techniques explored in machine learning privacy such as Membership Inference Attacks (MIAs), which heavily depend on LLMs' capability of verbatim memorization. However, this reliance presents challenges, especially given the vast amount of training data and the restricted number of effective training epochs. In this paper, we propose an adaptive pre-training data detection method which alleviates this reliance and effectively amplify the identification. Our method adaptively locates \textit{surprising tokens} of the input. A token is surprising to a LLM if the prediction on the token is "certain but wrong", which refers to low Shannon entropy of the probability distribution and low probability of the ground truth token at the same time. By using the prediction probability of surprising tokens to measure \textit{surprising}, the detection method is achieved based on the simple hypothesis that seeing seen data is less surprising for the model compared with seeing unseen data. The method can be applied without any access to the the pre-training data corpus or additional training like reference models. Our approach exhibits a consistent enhancement compared to existing methods in diverse experiments conducted on various benchmarks and models, achieving a maximum improvement of 29.5\%. We also introduce a new benchmark Dolma-Book developed upon a novel framework, which employs book data collected both before and after model training to provide further evaluation.

Automated soft moderation systems are unable to ascertain if a post supports or refutes a false claim, resulting in a large number of contextual false positives. This limits their effectiveness, for example undermining trust in health experts by adding warnings to their posts or resorting to vague warnings instead of granular fact-checks, which result in desensitizing users. In this paper, we propose to incorporate stance detection into existing automated soft-moderation pipelines, with the goal of ruling out contextual false positives and providing more precise recommendations for social media content that should receive warnings. We develop a textual deviation task called Contrastive Textual Deviation (CTD) and show that it outperforms existing stance detection approaches when applied to soft moderation.We then integrate CTD into the stateof-the-art system for automated soft moderation Lambretta, showing that our approach can reduce contextual false positives from 20% to 2.1%, providing another important building block towards deploying reliable automated soft moderation tools on social media.

Bevacizumab is a widely studied targeted therapeutic drug used in conjunction with standard chemotherapy for the treatment of recurrent ovarian cancer. While its administration has shown to increase the progression-free survival (PFS) in patients with advanced stage ovarian cancer, the lack of identifiable biomarkers for predicting patient response has been a major roadblock in its effective adoption towards personalized medicine. In this work, we leverage the latest histopathology foundation models trained on large-scale whole slide image (WSI) datasets to extract ovarian tumor tissue features for predicting bevacizumab response from WSIs. Our extensive experiments across a combination of different histopathology foundation models and multiple instance learning (MIL) strategies demonstrate capability of these large models in predicting bevacizumab response in ovarian cancer patients with the best models achieving an AUC score of 0.86 and an accuracy score of 72.5%. Furthermore, our survival models are able to stratify high- and low-risk cases with statistical significance (p < 0.05) even among the patients with the aggressive subtype of high-grade serous ovarian carcinoma. This work highlights the utility of histopathology foundation models for the task of ovarian bevacizumab response prediction from WSIs. The high-attention regions of the WSIs highlighted by these models not only aid the model explainability but also serve as promising imaging biomarkers for treatment prognosis.

Literature research, vital for scientific advancement, is overwhelmed by the vast ocean of available information. Addressing this, we propose an automated review generation method based on Large Language Models (LLMs) to streamline literature processing and reduce cognitive load. In case study on propane dehydrogenation (PDH) catalysts, our method swiftly generated comprehensive reviews from 343 articles, averaging seconds per article per LLM account. Extended analysis of 1041 articles provided deep insights into catalysts' composition, structure, and performance. Recognizing LLMs' hallucinations, we employed a multi-layered quality control strategy, ensuring our method's reliability and effective hallucination mitigation. Expert verification confirms the accuracy and citation integrity of generated reviews, demonstrating LLM hallucination risks reduced to below 0.5% with over 95% confidence. Released Windows application enables one-click review generation, aiding researchers in tracking advancements and recommending literature. This approach showcases LLMs' role in enhancing scientific research productivity and sets the stage for further exploration.