Graph classification in medical imaging and drug discovery requires accuracy and robust uncertainty quantification. To address this need, we introduce Conditional Prediction ROC (CP-ROC) bands, offering uncertainty quantification for ROC curves and robustness to distributional shifts in test data. Although developed for Tensorized Graph Neural Networks (TGNNs), CP-ROC is adaptable to general Graph Neural Networks (GNNs) and other machine learning models. We establish statistically guaranteed coverage for CP-ROC under a local exchangeability condition. This addresses uncertainty challenges for ROC curves under non-iid setting, ensuring reliability when test graph distributions differ from training data. Empirically, to establish local exchangeability for TGNNs, we introduce a data-driven approach to construct local calibration sets for graphs. Comprehensive evaluations show that CP-ROC significantly improves prediction reliability across diverse tasks. This method enhances uncertainty quantification efficiency and reliability for ROC curves, proving valuable for real-world applications with non-iid objects.

Gallbladder cancer (GBC) is the most frequent cause of disease among biliary tract neoplasms. Identifying the molecular mechanisms and biomarkers linked to GBC progression has been a significant challenge in scientific research. Few recent studies have explored the roles of biomarkers in GBC. Our study aimed to identify biomarkers in GBC using machine learning (ML) and bioinformatics techniques. We compared GBC tumor samples with normal samples to identify differentially expressed genes (DEGs) from two microarray datasets (GSE100363, GSE139682) obtained from the NCBI GEO database. A total of 146 DEGs were found, with 39 up-regulated and 107 down-regulated genes. Functional enrichment analysis of these DEGs was performed using Gene Ontology (GO) terms and REACTOME pathways through DAVID. The protein-protein interaction network was constructed using the STRING database. To identify hub genes, we applied three ranking algorithms: Degree, MNC, and Closeness Centrality. The intersection of hub genes from these algorithms yielded 11 hub genes. Simultaneously, two feature selection methods (Pearson correlation and recursive feature elimination) were used to identify significant gene subsets. We then developed ML models using SVM and RF on the GSE100363 dataset, with validation on GSE139682, to determine the gene subset that best distinguishes GBC samples. The hub genes outperformed the other gene subsets. Finally, NTRK2, COL14A1, SCN4B, ATP1A2, SLC17A7, SLIT3, COL7A1, CLDN4, CLEC3B, ADCYAP1R1, and MFAP4 were identified as crucial genes, with SLIT3, COL7A1, and CLDN4 being strongly linked to GBC development and prediction.

Automatic speech recognition (ASR) systems have traditionally been evaluated using English datasets, with the word error rate (WER) serving as the predominant metric. WER's simplicity and ease of interpretation have contributed to its widespread adoption, particularly for English. However, as ASR systems expand to multilingual contexts, WER fails in various ways, particularly with morphologically complex languages or those without clear word boundaries. Our work documents the limitations of WER as an evaluation metric and advocates for the character error rate (CER) as the primary metric in multilingual ASR evaluation. We show that CER avoids many of the challenges WER faces and exhibits greater consistency across writing systems. We support our proposition by conducting human evaluations of ASR transcriptions in three languages: Malayalam, English, and Arabic, which exhibit distinct morphological characteristics. We show that CER correlates more closely with human judgments than WER, even for English. To facilitate further research, we release our human evaluation dataset for future benchmarking of ASR metrics. Our findings suggest that CER should be prioritized, or at least supplemented, in multilingual ASR evaluations to account for the varying linguistic characteristics of different languages.

Assessing cognitive workload is crucial for human performance as it affects information processing, decision making, and task execution. Pupil size is a valuable indicator of cognitive workload, reflecting changes in attention and arousal governed by the autonomic nervous system. Cognitive events are closely linked to cognitive workload as they activate mental processes and trigger cognitive responses. This study explores the potential of using machine learning to automatically detect cognitive events experienced using individuals. We framed the problem as a binary classification task, focusing on detecting stimulus onset across four cognitive tasks using CNN models and 1-second pupillary data. The results, measured by Matthew's correlation coefficient, ranged from 0.47 to 0.80, depending on the cognitive task. This paper discusses the trade-offs between generalization and specialization, model behavior when encountering unseen stimulus onset times, structural variances among cognitive tasks, factors influencing model predictions, and real-time simulation. These findings highlight the potential of machine learning techniques in detecting cognitive events based on pupil and eye movement responses, contributing to advancements in personalized learning and optimizing neurocognitive workload management.

In this study, we leverage state-of-the-art Natural Language Processing (NLP) techniques to perform sentiment analysis on Amazon product reviews. By employing transformer-based models, RoBERTa, we analyze a vast dataset to derive sentiment scores that accurately reflect the emotional tones of the reviews. We provide an in-depth explanation of the underlying principles of these models and evaluate their performance in generating sentiment scores. Further, we conduct comprehensive data analysis and visualization to identify patterns and trends in sentiment scores, examining their alignment with behavioral economics principles such as electronic word of mouth (eWOM), consumer emotional reactions, and the confirmation bias. Our findings demonstrate the efficacy of advanced NLP models in sentiment analysis and offer valuable insights into consumer behavior, with implications for strategic decision-making and marketing practices.

This study investigates the application of an artificial neural network framework for analysing water pollution caused by solids. Water pollution by suspended solids poses significant environmental and health risks. Traditional methods for assessing and predicting pollution levels are often time-consuming and resource-intensive. To address these challenges, we developed a model that leverages a comprehensive dataset of water quality from total suspended solids. A convolutional neural network was trained under a transfer learning approach using data corresponding to different total suspended solids concentrations, with the goal of accurately predicting low, medium and high pollution levels based on various input variables. Our model demonstrated high predictive accuracy, outperforming conventional statistical methods in terms of both speed and reliability. The results suggest that the artificial neural network framework can serve as an effective tool for real-time monitoring and management of water pollution, facilitating proactive decision-making and policy formulation. This approach not only enhances our understanding of pollution dynamics but also underscores the potential of machine learning techniques in environmental science.

Alzheimer's disease (AD) is a leading neurodegenerative condition and the primary cause of dementia, characterized by progressive cognitive decline and memory loss. Its progression, marked by shrinkage in the cerebral cortex, is irreversible. Numerous machine learning algorithms have been proposed for the early diagnosis of AD. However, they often struggle with the issues of noise, outliers, and class imbalance. To tackle the aforementioned limitations, in this article, we introduce a novel, robust, and flexible membership scheme called Flexi-Fuzz. This scheme integrates a novel flexible weighting mechanism, class probability, and imbalance ratio. The proposed flexible weighting mechanism assigns the maximum weight to samples within a specific proximity to the center, with a gradual decrease in weight beyond a certain threshold. This approach ensures that samples near the class boundary still receive significant weight, maintaining their influence in the classification process. Class probability is used to mitigate the impact of noisy samples, while the imbalance ratio addresses class imbalance. Leveraging this, we incorporate the proposed Flexi-Fuzz membership scheme into the least squares support vector machines (LSSVM) framework, resulting in a robust and flexible model termed Flexi-Fuzz-LSSVM. We determine the class-center using two methods: the conventional mean approach and an innovative median approach, leading to two model variants, Flexi-Fuzz-LSSVM-I and Flexi-Fuzz-LSSVM-II. To validate the effectiveness of the proposed Flexi-Fuzz-LSSVM models, we evaluated them on benchmark UCI and KEEL datasets, both with and without label noise. Additionally, we tested the models on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset for AD diagnosis. Experimental results demonstrate the superiority of the Flexi-Fuzz-LSSVM models over baseline models.

The robustness of Vision-Language Models (VLMs) such as CLIP is critical for their deployment in safety-critical applications like autonomous driving, healthcare diagnostics, and security systems, where accurate interpretation of visual and textual data is essential. However, these models are highly susceptible to adversarial attacks, which can severely compromise their performance and reliability in real-world scenarios. Previous methods have primarily focused on improving robustness through adversarial training and generating adversarial examples using models like FGSM, AutoAttack, and DeepFool. However, these approaches often rely on strong assumptions, such as fixed perturbation norms or predefined attack patterns, and involve high computational complexity, making them challenging to implement in practical settings. In this paper, we propose a novel adversarial training framework that integrates multiple attack strategies and advanced machine learning techniques to significantly enhance the robustness of VLMs against a broad range of adversarial attacks. Experiments conducted on real-world datasets, including CIFAR-10 and CIFAR-100, demonstrate that the proposed method significantly enhances model robustness. The fine-tuned CLIP model achieved an accuracy of 43.5% on adversarially perturbed images, compared to only 4% for the baseline model. The neural network model achieved a high accuracy of 98% in these challenging classification tasks, while the XGBoost model reached a success rate of 85.26% in prediction tasks.

Cryptocurrencies, as decentralized digital assets, have experienced rapid growth and adoption, with over 23,000 cryptocurrencies and a market capitalization nearing \$1.1 trillion (about \$3,400 per person in the US) as of 2023. This dynamic market presents significant opportunities and risks, highlighting the need for accurate price prediction models to manage volatility. This chapter comprehensively reviews machine learning (ML) techniques applied to cryptocurrency price prediction from 2014 to 2024. We explore various ML algorithms, including linear models, tree-based approaches, and advanced deep learning architectures such as transformers and large language models. Additionally, we examine the role of sentiment analysis in capturing market sentiment from textual data like social media posts and news articles to anticipate price fluctuations. With expertise in optimizing complex systems and processes, industrial engineers are pivotal in enhancing these models. They contribute by applying principles of process optimization, efficiency, and risk mitigation to improve computational performance and data management. This chapter highlights the evolving landscape of cryptocurrency price prediction, the integration of emerging technologies, and the significant role of industrial engineers in refining predictive models. By addressing current limitations and exploring future research directions, this chapter aims to advance the development of more accurate and robust prediction systems, supporting better-informed investment decisions and more stable market behavior.

In an era increasingly focused on green computing and explainable AI, revisiting traditional approaches in theoretical and phenomenological particle physics is paramount. This project evaluates various machine learning (ML) algorithms-including Nearest Neighbors, Decision Trees, Random Forest, AdaBoost, Naive Bayes, Quadratic Discriminant Analysis (QDA), and XGBoost-alongside standard neural networks and a novel Physics-Informed Neural Network (PINN) for physics data analysis. We apply these techniques to a binary classification task that distinguishes the experimental viability of simulated scenarios based on Higgs observables and essential parameters. Through this comprehensive analysis, we aim to showcase the capabilities and computational efficiency of each model in binary classification tasks, thereby contributing to the ongoing discourse on integrating ML and Deep Neural Networks (DNNs) into physics research. In this study, XGBoost emerged as the preferred choice among the evaluated machine learning algorithms for its speed and effectiveness, especially in the initial stages of computation with limited datasets. However, while standard Neural Networks and Physics-Informed Neural Networks (PINNs) demonstrated superior performance in terms of accuracy and adherence to physical laws, they require more computational time. These findings underscore the trade-offs between computational efficiency and model sophistication.