Gastrointestinal (GI) and liver diseases have become increasingly prevalent across the globe, largely due to factors such as industrialization, dietary shifts, and the widespread use of antibiotics. These diseases pose significant diagnostic and treatment challenges, emphasizing the need for advanced medical technologies. Video Capsule Endoscopy (VCE) is a key non-invasive tool for examining the GI tract, especially in diagnosing conditions related to the small intestine, such as Crohn's disease, Celiac disease, and GI cancer. Unlike traditional endoscopy, VCE involves a small, pill-sized camera that travels through the digestive tract, capturing detailed images without sedation or invasive procedures. This method offers a comprehensive view of areas that are difficult to reach using conventional endoscopy. Despite its advantages, VCE faces challenges in practical application. A typical VCE procedure can generate between 57,000 to 1,000,000 images for 6-8 hours, which gastroenterologists must review.

The Matrix-Element Method (MEM) has long been a cornerstone of data analysis in high-energy physics. It leverages theoretical knowledge of parton-level processes and symmetries to evaluate the likelihood of observed events. In parallel, the advent of geometric deep learning has enabled neural network architectures that incorporate known symmetries directly into their design, leading to more efficient learning. This paper presents a novel approach that combines MEM-inspired symmetry considerations with equivariant neural network design for particle physics analysis. Even though Lorentz invariance and permutation invariance overall reconstructed objects are the largest and most natural symmetry in the input domain, we find that they are sub-optimal in most practical search scenarios. We propose a longitudinal boost-equivariant message-passing neural network architecture that preserves relevant discrete symmetries. We present numerical studies demonstrating MEM-inspired architectures achieve new state-of-the-art performance in distinguishing di-Higgs decays to four bottom quarks from the QCD background, with enhanced sample and parameter efficiencies. This synergy between MEM and equivariant deep learning opens new directions for physics-informed architecture design, promising more powerful tools for probing physics beyond the Standard Model.

Fair lending practices and model interpretability are crucial concerns in the financial industry, especially given the increasing use of complex machine learning models. In response to the Consumer Financial Protection Bureau's (CFPB) requirement to protect consumers against unlawful discrimination, we introduce LDA-XGB1, a novel less discriminatory alternative (LDA) machine learning model for fair and interpretable binary classification. LDA-XGB1 is developed through biobjective optimization that balances accuracy and fairness, with both objectives formulated using binning and information value. It leverages the predictive power and computational efficiency of XGBoost while ensuring inherent model interpretability, including the enforcement of monotonic constraints. We evaluate LDA-XGB1 on two datasets: SimuCredit, a simulated credit approval dataset, and COMPAS, a real-world recidivism prediction dataset. Our results demonstrate that LDA-XGB1 achieves an effective balance between predictive accuracy, fairness, and interpretability, often outperforming traditional fair lending models. This approach equips financial institutions with a powerful tool to meet regulatory requirements for fair lending while maintaining the advantages of advanced machine learning techniques.

Relation extraction (RE) aims to identify semantic relationships between entities within text. Despite considerable advancements, existing models predominantly require extensive annotated training data, which is both costly and labor-intensive to collect. Moreover, these models often struggle to adapt to new or unseen relations. Few-shot learning, aiming to lessen annotation demands, typically provides incomplete and biased supervision for target relations, leading to degraded and unstable performance. To accurately and explicitly describe relation semantics while minimizing annotation demands, we explore the definition only zero-shot RE setting where only relation definitions expressed in natural language are used to train a RE model. We introduce REPaL, comprising three stages: (1) We leverage large language models (LLMs) to generate initial seed instances from relation definitions and an unlabeled corpus. (2) We fine-tune a bidirectional Small Language Model (SLM) with initial seeds to learn relations for the target domain. (3) We expand pattern coverage and mitigate bias from initial seeds by integrating feedback from the SLM's predictions on the unlabeled corpus and the synthesis history. To accomplish this, we leverage the multi-turn conversation ability of LLMs to generate new instances in follow-up dialogues, informed by both the feedback and synthesis history. Studies reveal that definition-oriented seed synthesis enhances pattern coverage whereas indiscriminately increasing seed quantity leads to performance saturation. Experiments on two datasets show REPaL significantly improved cost-effective zero-shot performance by large margins.

The recent explosion of high-quality language models has necessitated new methods for identifying AI-generated text. Watermarking is a leading solution and could prove to be an essential tool in the age of generative AI. Existing approaches embed watermarks at inference and crucially rely on the large language model (LLM) specification and parameters being secret, which makes them inapplicable to the open-source setting. In this work, we introduce the first watermarking scheme for open-source LLMs. Our scheme works by modifying the parameters of the model, but the watermark can be detected from just the outputs of the model. Perhaps surprisingly, we prove that our watermarks are unremovable under certain assumptions about the adversary's knowledge. To demonstrate the behavior of our construction under concrete parameter instantiations, we present experimental results with OPT-6.7B and OPT-1.3B. We demonstrate robustness to both token substitution and perturbation of the model parameters. We find that the stronger of these attacks, the model-perturbation attack, requires deteriorating the quality score to 0 out of 100 in order to bring the detection rate down to 50%. As generative AI becomes increasingly capable and available, reliable solutions for identifying AIgenerated text grow more and more imperative.

Recent advancements in artificial intelligence promise ample potential in monitoring applications with surveillance cameras. However, concerns about privacy and model bias have made it challenging to utilize them in public. Although de-identification approaches have been proposed in the literature, aiming to achieve a certain level of anonymization, most of them employ deep learning models that are computationally demanding for real-time edge deployment. In this study, we revisit conventional anonymization solutions for privacy protection and real-time video anomaly detection (VAD) applications. We propose a novel lightweight adaptive anonymization for VAD (LA3D) that employs dynamic adjustment to enhance privacy protection. We evaluated the approaches on publicly available privacy and VAD data sets to examine the strengths and weaknesses of the different anonymization techniques and highlight the promising efficacy of our approach. Our experiment demonstrates that LA3D enables substantial improvement in the privacy anonymization capability without majorly degrading VAD efficacy.

The Internet has significantly expanded the potential for global collaboration, allowing millions of users to contribute to collective projects like Wikipedia. While prior work has assessed the success of online collaborations, most approaches are time-agnostic, evaluating success without considering its longevity. Research on the factors that ensure the long-term preservation of high-quality standards in online collaboration is scarce. In this study, we address this gap. We propose a novel metric, `Sustainable Success,' which measures the ability of collaborative efforts to maintain their quality over time. Using Wikipedia as a case study, we introduce the SustainPedia dataset, which compiles data from over 40K Wikipedia articles, including each article's sustainable success label and more than 300 explanatory features such as edit history, user experience, and team composition. Using this dataset, we develop machine learning models to predict the sustainable success of Wikipedia articles. Our best-performing model achieves a high AU-ROC score of 0.88 on average. Our analysis reveals important insights. For example, we find that the longer an article takes to be recognized as high-quality, the more likely it is to maintain that status over time (i.e., be sustainable). Additionally, user experience emerged as the most critical predictor of sustainability. Our analysis provides insights into broader collective actions beyond Wikipedia (e.g., online activism, crowdsourced open-source software), where the same social dynamics that drive success on Wikipedia might play a role. We make all data and code used for this study publicly available for further research.

Multi-view data provides complementary information on the same set of observations, with multi-omics and multimodal sensor data being common examples. Analyzing such data typically requires distinguishing between shared (joint) and unique (individual) signal subspaces from noisy, high-dimensional measurements. Despite many proposed methods, the conditions for reliably identifying joint and individual subspaces remain unclear. We rigorously quantify these conditions, which depend on the ratio of the signal rank to the ambient dimension, principal angles between true subspaces, and noise levels. Our approach characterizes how spectrum perturbations of the product of projection matrices, derived from each view's estimated subspaces, affect subspace separation. Using these insights, we provide an easy-to-use and scalable estimation algorithm. In particular, we employ rotational bootstrap and random matrix theory to partition the observed spectrum into joint, individual, and noise subspaces. Diagnostic plots visualize this partitioning, providing practical and interpretable insights into the estimation performance. In simulations, our method estimates joint and individual subspaces more accurately than existing approaches. Applications to multi-omics data from colorectal cancer patients and nutrigenomic study of mice demonstrate improved performance in downstream predictive tasks.

Differential privacy (DP) is applied when fine-tuning pre-trained large language models (LLMs) to limit leakage of training examples. While most DP research has focused on improving a model's privacy-utility tradeoff, some find that DP can be unfair to or biased against underrepresented groups. In this work, we show the impact of DP on bias in LLMs through empirical analysis. Differentially private training can increase the model bias against protected groups w.r.t AUC-based bias metrics. DP makes it more difficult for the model to differentiate between the positive and negative examples from the protected groups and other groups in the rest of the population. Our results also show that the impact of DP on bias is not only affected by the privacy protection level but also the underlying distribution of the dataset.

This study explored how lifestyle, personal background, and family history contribute to the risk of developing Alcohol Use Disorder (AUD). Survey data from the All of Us Program was utilized to extract information on AUD status, lifestyle, personal background, and family history for 6,016 participants. Key determinants of AUD were identified using decision trees including annual income, recreational drug use, length of residence, sex/gender, marital status, education level, and family history of AUD. Data visualization and Chi-Square Tests of Independence were then used to assess associations between identified factors and AUD. Afterwards, machine learning techniques including decision trees, random forests, and Naive Bayes were applied to predict an individual's likelihood of developing AUD. Random forests were found to achieve the highest accuracy (82%), compared to Decision Trees and Naive Bayes. Findings from this study can offer insights that help parents, healthcare professionals, and educators develop strategies to reduce AUD risk, enabling early intervention and targeted prevention efforts.