Explainable intrusion detection systems (IDS) are now recognized as essential for mission-critical networks, yet most "XAI" pipelines still bolt an approximate explainer onto an opaque classifier, leaving analysts with partial and sometimes misleading insights. The Interpretable Generalization (IG) mechanism, published in IEEE Transactions on Information Forensics and Security, eliminates that bottleneck by learning coherent patterns - feature combinations unique to benign or malicious traffic - and turning them into fully auditable rules. IG already delivers outstanding precision, recall, and AUC on NSL-KDD, UNSW-NB15, and UKM-IDS20, even when trained on only 10% of the data. To raise precision further without sacrificing transparency, we introduce Multi-Granular Discretization (IG-MD), which represents every continuous feature at several Gaussian-based resolutions. On UKM-IDS20, IG-MD lifts precision by greater than or equal to 4 percentage points across all nine train-test splits while preserving recall approximately equal to 1.0, demonstrating that a single interpretation-ready model can scale across domains without bespoke tuning.

The integration of Large Language Models (LLMs) in K--12 education offers both transformative opportunities and emerging risks. This study explores how students may Trojanize prompts to elicit unsafe or unintended outputs from LLMs, bypassing established content moderation systems with safety guardrils. Through a systematic experiment involving simulated K--12 queries and multi-turn dialogues, we expose key vulnerabilities in GPT-3.5 and GPT-4. This paper presents our experimental design, detailed findings, and a prototype tool, TrojanPromptGuard (TPG), to automatically detect and mitigate Trojanized educational prompts. These insights aim to inform both AI safety researchers and educational technologists on the safe deployment of LLMs for educators.

This paper presents a novel framework for pattern prediction and system prognostics centered on Spatiotemporal Permutation Entropy analysis integrated with Boosted Enhanced Quantile Regression Neural Networks (BEQRNNs). We address the challenge of understanding complex dynamical patterns in multidimensional systems through an approach that combines entropy-based complexity measures with advanced neural architectures. The system leverages dual computational stages: first implementing spatiotemporal entropy extraction optimized for multiscale temporal and spatial data streams, followed by an integrated BEQRNN layer that enables probabilistic pattern prediction with uncertainty quantification. This architecture achieves 81.17% accuracy in spatiotemporal pattern classification with prediction horizons up to 200 time steps and maintains robust performance across diverse regimes. Field testing across chaotic attractors, reaction-diffusion systems, and industrial datasets shows a 79% increase in critical transition detection accuracy and 81.22% improvement in long-term prediction reliability. The framework's effectiveness in processing complex, multimodal entropy features demonstrates significant potential for real-time prognostic applications.

Preclinical sleep research remains constrained by labor intensive, manual vigilance state classification and inter rater variability, limiting throughput and reproducibility. This study presents an automated framework developed by Team Neural Prognosticators to classify electroencephalogram (EEG) recordings of small rodents into three critical vigilance states paradoxical sleep (REM), slow wave sleep (SWS), and wakefulness. The system integrates advanced signal processing with machine learning, leveraging engineered features from both time and frequency domains, including spectral power across canonical EEG bands (delta to gamma), temporal dynamics via Maximum-Minimum Distance, and cross-frequency coupling metrics. These features capture distinct neurophysiological signatures such as high frequency desynchronization during wakefulness, delta oscillations in SWS, and REM specific bursts. Validated during the 2024 Big Data Health Science Case Competition (University of South Carolina Big Data Health Science Center, 2024), our XGBoost model achieved 91.5% overall accuracy, 86.8% precision, 81.2% recall, and an F1 score of 83.5%, outperforming all baseline methods. Our approach represents a critical advancement in automated sleep state classification and a valuable tool for accelerating discoveries in sleep science and the development of targeted interventions for chronic sleep disorders. As a publicly available code (BDHSC) resource is set to contribute significantly to advancements.

Recent advancements in Vision-Language Models like CLIP have enabled zero-shot OOD detection by leveraging both image and textual label information. Among these, negative label-based methods such as NegLabel and CSP have shown promising results by utilizing a lexicon of words to define negative labels for distinguishing OOD samples. However, these methods suffer from detecting in-distribution samples as OOD due to negative labels that are subcategories of in-distribution labels or proper nouns. They also face limitations in handling images that match multiple in-distribution and negative labels. W e propose NegRefine, a novel negative label refinement framework for zero-shot OOD detection. By introducing a filtering mechanism to exclude subcategory labels and proper nouns from the negative label set and incorporating a multi-matching-aware scoring function that dynamically adjusts the contributions of multiple labels matching an image, NegRefine ensures a more robust separation between in-distribution and OOD samples. W e evaluate NegRefine on large-scale benchmarks, including ImageNet-1K.

The Nyström method is a popular low-rank approximation technique for large matrices that arise in kernel methods and convex optimization. Yet, when the data exhibits heavy-tailed spectral decay, the effective dimension of the problem often becomes so large that even the Nyström method may be outside of our computational budget. To address this, we propose Block-Nyström, an algorithm that injects a block-diagonal structure into the Nyström method, thereby significantly reducing its computational cost while recovering strong approximation guarantees. We show that Block-Nyström can be used to construct improved preconditioners for second-order optimization, as well as to efficiently solve kernel ridge regression for statistical learning over Hilbert spaces. Our key technical insight is that, within the same computational budget, combining several smaller Nyström approximations leads to stronger tail estimates of the input spectrum than using one larger approximation. Along the way, we provide a novel recursive preconditioning scheme for efficiently inverting the Block-Nyström matrix, and provide new statistical learning bounds for a broad class of approximate kernel ridge regression solvers.

We analyze the extent to which internal representations of language models (LMs) identify and distinguish mentions of named entities, focusing on the many-to-many correspondence between entities and their mentions. We first formulate two problems of entity mentions -- ambiguity and variability -- and propose a framework analogous to clustering quality metrics. Specifically, we quantify through cluster analysis of LM internal representations the extent to which mentions of the same entity cluster together and mentions of different entities remain separated. Our experiments examine five Transformer-based autoregressive models, showing that they effectively identify and distinguish entities with metrics analogous to precision and recall ranging from 0.66 to 0.9. Further analysis reveals that entity-related information is compactly represented in a low-dimensional linear subspace at early LM layers. Additionally, we clarify how the characteristics of entity representations influence word prediction performance. These findings are interpreted through the lens of isomorphism between LM representations and entity-centric knowledge structures in the real world, providing insights into how LMs internally organize and use entity information.

The identification of drug-target interactions (DTI) is critical for drug discovery and repositioning, as it reveals potential therapeutic uses of existing drugs, accelerating development and reducing costs. However, most existing models focus only on direct similarity in homogeneous graphs, failing to exploit the rich similarity in heterogeneous graphs. To address this gap, inspired by real-world social interaction behaviors, we propose SOC-DGL, which comprises two specialized modules: the Affinity-Driven Graph Learning (ADGL) module, learning global similarity through an affinity-enhanced drug-target graph, and the Equilibrium-Driven Graph Learning (EDGL) module, capturing higher-order similarity by amplifying the influence of even-hop neighbors using an even-polynomial graph filter based on balance theory. This dual approach enables SOC-DGL to effectively capture similarity information across multiple interaction scales within affinity and association matrices. To address the issue of imbalance in DTI datasets, we propose an adjustable imbalance loss function that adjusts the weight of negative samples by the parameter. Extensive experiments on four benchmark datasets demonstrate that SOC-DGL consistently outperforms existing state-of-the-art methods across both balanced and imbalanced scenarios. Moreover, SOC-DGL successfully predicts the top 9 drugs known to bind ABL1, and further analyzed the 10th drug, which has not been experimentally confirmed to interact with ABL1, providing supporting evidence for its potential binding.

To facilitate robust and trustworthy deployment of large language models (LLMs), it is essential to quantify the reliability of their generations through uncertainty estimation. While recent efforts have made significant advancements by leveraging the internal logic and linguistic features of LLMs to estimate uncertainty scores, our empirical analysis highlights the pitfalls of these methods to strike a harmonized estimation between indication, balance, and calibration, which hinders their broader capability for accurate uncertainty estimation. To address this challenge, we propose CUE (Corrector for Uncertainty Estimation): A straightforward yet effective method that employs a lightweight model trained on data aligned with the target LLM's performance to adjust uncertainty scores. Comprehensive experiments across diverse models and tasks demonstrate its effectiveness, which achieves consistent improvements of up to 60% over existing methods.

Kolmogorov Arnold Networks (KANs) are recent architectural advancement in neural computation that offer a mathematically grounded alternative to standard neural networks. This study presents an empirical evaluation of KANs in context of class imbalanced classification, using ten benchmark datasets. We observe that KANs can inherently perform well on raw imbalanced data more effectively than Multi-Layer Perceptrons (MLPs) without any resampling strategy. However, conventional imbalance strategies fundamentally conflict with KANs mathematical structure as resampling and focal loss implementations significantly degrade KANs performance, while marginally benefiting MLPs. Crucially, KANs suffer from prohibitive computational costs without proportional performance gains. Statistical validation confirms that MLPs with imbalance techniques achieve equivalence with KANs (|d| < 0.08 across metrics) at minimal resource costs. These findings reveal that KANs represent a specialized solution for raw imbalanced data where resources permit. But their severe performance-resource tradeoffs and incompatibility with standard resampling techniques currently limits practical deployment. We identify critical research priorities as developing KAN specific architectural modifications for imbalance learning, optimizing computational efficiency, and theoretical reconciling their conflict with data augmentation. This work establishes foundational insights for next generation KAN architectures in imbalanced classification scenarios.