The increasing availability of personal data has enabled significant advances in fields such as machine learning, healthcare, and cybersecurity. However, this data abundance also raises serious privacy concerns, especially in light of powerful re-identification attacks and growing legal and ethical demands for responsible data use. Differential privacy (DP) has emerged as a principled, mathematically grounded framework for mitigating these risks. This review provides a comprehensive survey of DP, covering its theoretical foundations, practical mechanisms, and real-world applications. It explores key algorithmic tools and domain-specific challenges - particularly in privacy-preserving machine learning and synthetic data generation. The report also highlights usability issues and the need for improved communication and transparency in DP systems. Overall, the goal is to support informed adoption of DP by researchers and practitioners navigating the evolving landscape of data privacy.

Generating synthetic tabular data can be challenging, however evaluation of their quality is just as challenging, if not more. This systematic review sheds light on the critical importance of rigorous evaluation of synthetic health data to ensure reliability, relevance, and their appropriate use. Based on screening of 1766 papers and a detailed review of 101 papers we identified key challenges, including lack of consensus on evaluation methods, improper use of evaluation metrics, limited input from domain experts, inadequate reporting of dataset characteristics, and limited reproducibility of results. In response, we provide several guidelines on the generation and evaluation of synthetic data, to allow the community to unlock and fully harness the transformative potential of synthetic data and accelerate innovation.

Open-set detection is crucial for robust UAV autonomy in air-to-air object detection under real-world conditions. Traditional closed-set detectors degrade significantly under domain shifts and flight data corruption, posing risks to safety-critical applications. We propose a novel, model-agnostic open-set detection framework designed specifically for embedding-based detectors. The method explicitly handles unknown object rejection while maintaining robustness against corrupted flight data. It estimates semantic uncertainty via entropy modeling in the embedding space and incorporates spectral normalization and temperature scaling to enhance open-set discrimination. We validate our approach on the challenging AOT aerial benchmark and through extensive real-world flight tests. Comprehensive ablation studies demonstrate consistent improvements over baseline methods, achieving up to a 10\% relative AUROC gain compared to standard YOLO-based detectors. Additionally, we show that background rejection further strengthens robustness without compromising detection accuracy, making our solution particularly well-suited for reliable UAV perception in dynamic air-to-air environments.

The intelligent fault diagnosis of rotating mechanical equipment usually requires a large amount of labeled sample data. However, in practical industrial applications, acquiring enough data is both challenging and expensive in terms of time and cost. Moreover, different types of rotating mechanical equipment with different unique mechanical properties, require separate training of diagnostic models for each case. To address the challenges of limited fault samples and the lack of generalizability in prediction models for practical engineering applications, we propose a Multi-Attention Meta Transformer method for few-shot unsupervised rotating machinery fault diagnosis (MMT-FD). This framework extracts potential fault representations from unlabeled data and demonstrates strong generalization capabilities, making it suitable for diagnosing faults across various types of mechanical equipment. The MMT-FD framework integrates a time-frequency domain encoder and a meta-learning generalization model. The time-frequency domain encoder predicts status representations generated through random augmentations in the time-frequency domain. These enhanced data are then fed into a meta-learning network for classification and generalization training, followed by fine-tuning using a limited amount of labeled data. The model is iteratively optimized using a small number of contrastive learning iterations, resulting in high efficiency. To validate the framework, we conducted experiments on a bearing fault dataset and rotor test bench data. The results demonstrate that the MMT-FD model achieves 99\% fault diagnosis accuracy with only 1\% of labeled sample data, exhibiting robust generalization capabilities.

Background and objective Early diagnosis of gastric diseases is crucial to prevent fatal outcomes. Although histopathologic examination remains the diagnostic gold standard, it is performed entirely manually, making evaluations labor-intensive and prone to variability among pathologists. Critical findings may be missed, and lack of standard procedures reduces consistency. These limitations highlight the need for automated, reliable, and efficient methods for gastric tissue analysis. Methods In this study, a novel hybrid model named CoAtNeXt was proposed for the classification of gastric tissue images. The model is built upon the CoAtNet architecture by replacing its MBConv layers with enhanced ConvNeXtV2 blocks. Additionally, the Convolutional Block Attention Module (CBAM) is integrated to improve local feature extraction through channel and spatial attention mechanisms. The architecture was scaled to achieve a balance between computational efficiency and classification performance. CoAtNeXt was evaluated on two publicly available datasets, HMU-GC-HE-30K for eight-class classification and GasHisSDB for binary classification, and was compared against 10 Convolutional Neural Networks (CNNs) and ten Vision Transformer (ViT) models. Results CoAtNeXt achieved 96.47% accuracy, 96.60% precision, 96.47% recall, 96.45% F1 score, and 99.89% AUC on HMU-GC-HE-30K. On GasHisSDB, it reached 98.29% accuracy, 98.07% precision, 98.41% recall, 98.23% F1 score, and 99.90% AUC. It outperformed all CNN and ViT models tested and surpassed previous studies in the literature. Conclusion Experimental results show that CoAtNeXt is a robust architecture for histopathological classification of gastric tissue images, providing performance on binary and multiclass. Its highlights its potential to assist pathologists by enhancing diagnostic accuracy and reducing workload.

Audio deepfake detection (ADD) models are commonly evaluated using datasets that combine multiple synthesizers, with performance reported as a single Equal Error Rate (EER). However, this approach disproportionately weights synthesizers with more samples, underrepresenting others and reducing the overall reliability of EER. Additionally, most ADD datasets lack diversity in bona fide speech, often featuring a single environment and speech style (e.g., clean read speech), limiting their ability to simulate real-world conditions. To address these challenges, we propose bona fide cross-testing, a novel evaluation framework that incorporates diverse bona fide datasets and aggregates EERs for more balanced assessments. Our approach improves robustness and interpretability compared to traditional evaluation methods. We benchmark over 150 synthesizers across nine bona fide speech types and release a new dataset to facilitate further research at https://github.com/cyaaronk/audio_deepfake_eval.

West Lafayette, Indiana, USA Abstract--Zero-shot V oice Cloning (VC) and T ext-to-Speech (TTS) methods have advanced rapidly, enabling the generation of highly realistic synthetic speech and raising serious concerns about their misuse. While numerous detectors have been developed for English and Chinese, Spanish--spoken by over 600 million people worldwide--remains underrepresented in speech forensics. T o address this gap, we introduce HISPASpoof, the first large-scale Spanish dataset designed for synthetic speech detection and attribution. It includes real speech from public corpora across six accents and synthetic speech generated with six zero-shot TTS systems. We evaluate five representative methods, showing that detectors trained on English fail to generalize to Spanish, while training on HISPASpoof substantially improves detection. We also evaluate synthetic speech attribution performance on HISPASpoof, i.e., identifying the generation method of synthetic speech. HISPASpoof thus provides a critical benchmark for advancing reliable and inclusive speech forensics in Spanish. The rapid advancement of speech synthesis techniques has significantly transformed the area of audio generation and speech forensics. Recent Text-to-Speech (TTS) and V oice Cloning (VC) methods [1], [2], [3], [4], [5], [6] are now capable of producing highly realistic synthetic voices that closely mimic the spectral, prosodic, and linguistic traits of real human speech [7], [8], [9], [10].

Antibody binding site prediction plays a pivotal role in computational immunology and therapeutic antibody design. Existing sequence or structure methods rely on single-view features and fail to identify antibody-specific binding sites on the antigens. In this paper, we propose \textbf{CAME-AB}, a novel Cross-modality Attention framework with a Mixture-of-Experts (MoE) backbone for robust antibody binding site prediction. CAME-AB integrates five biologically grounded modalities, including raw amino acid encodings, BLOSUM substitution profiles, pretrained language model embeddings, structure-aware features, and GCN-refined biochemical graphs, into a unified multimodal representation. To enhance adaptive cross-modal reasoning, we propose an \emph{adaptive modality fusion} module that learns to dynamically weight each modality based on its global relevance and input-specific contribution. A Transformer encoder combined with an MoE module further promotes feature specialization and capacity expansion. We additionally incorporate a supervised contrastive learning objective to explicitly shape the latent space geometry, encouraging intra-class compactness and inter-class separability. To improve optimization stability and generalization, we apply stochastic weight averaging during training. Extensive experiments on benchmark antibody-antigen datasets demonstrate that CAME-AB consistently outperforms strong baselines on multiple metrics, including Precision, Recall, F1-score, AUC-ROC, and MCC. Ablation studies further validate the effectiveness of each architectural component and the benefit of multimodal feature integration. The model implementation details and the codes are available on https://anonymous.4open.science/r/CAME-AB-C525

If we use LLMs as judges to evaluate the complex decisions of other LLMs, who or what monitors the judges? Infinite monitoring chains are inevitable whenever we do not know the ground truth of the decisions by experts and we do not want to trust them. One way to ameliorate our evaluation uncertainty is to exploit the use of logical consistency between disagreeing experts. By observing how LLM judges agree and disagree while grading other LLMs, we can compute the only possible evaluations of their grading ability. For example, if two LLM judges disagree on which tasks a third one completed correctly, they cannot both be 100\% correct in their judgments. This logic can be formalized as a Linear Programming problem in the space of integer response counts for any finite test. We use it here to develop no-knowledge alarms for misaligned LLM judges. The alarms can detect, with no false positives, that at least one member or more of an ensemble of judges are violating a user specified grading ability requirement.

Unsustainable trade in wildlife is a major threat to biodiversity and is now increasingly prevalent in digital marketplaces and social media. With the sheer volume of digital content, the need for automated methods to detect wildlife trade listings is growing. These methods are especially needed for the automatic identification of wildlife products, such as ivory. We developed machine learning-based object recognition models that can identify wildlife products within images and highlight them. The data consists of images of elephant, pangolin, and tiger products that were identified as being sold illegally or that were confiscated by authorities. Specifically, the wildlife products included elephant ivory and skins, pangolin scales, and claws (raw and crafted), and tiger skins and bones. We investigated various combinations of training strategies and two loss functions to identify the best model to use in the automatic detection of these wildlife products. Models were trained for each species while also developing a single model to identify products from all three species. The best model showed an overall accuracy of 84.2% with accuracies of 71.1%, 90.2% and 93.5% in detecting products derived from elephants, pangolins, and tigers, respectively. We further demonstrate that the machine learning model can be made easily available to stakeholders, such as government authorities and law enforcement agencies, by developing a smartphone-based application that had an overall accuracy of 91.3%. The application can be used in real time to click images and help identify potentially prohibited products of target species. Thus, the proposed method is not only applicable for monitoring trade on the web but can also be used e.g. in physical markets for monitoring wildlife trade.