Anomaly detection in spatiotemporal data is a challenging problem encountered in a variety of applications, including video surveillance, medical imaging data, and urban traffic monitoring. Existing anomaly detection methods focus mainly on point anomalies and cannot deal with temporal and spatial dependencies that arise in spatio-temporal data. Tensor-based anomaly detection methods have been proposed to address this problem. Although existing methods can capture dependencies across different modes, they are primarily supervised and do not account for the specific structure of anomalies. Moreover, these methods focus mainly on extracting anomalous features without providing any statistical confidence. In this paper, we introduce an unsupervised tensor-based anomaly detection method that simultaneously considers the sparse and spatiotemporally smooth nature of anomalies. The anomaly detection problem is formulated as a regularized robust low-rank + sparse tensor decomposition where the total variation of the tensor with respect to the underlying spatial and temporal graphs quantifies the spatiotemporal smoothness of the anomalies. Once the anomalous features are extracted, we introduce a statistical anomaly scoring framework that accounts for local spatio-temporal dependencies. The proposed framework is evaluated on both synthetic and real data.

The exponential growth of internet generated data has fueled advancements in artificial intelligence (AI), machine learning (ML), and deep learning (DL) for extracting actionable insights in marketing,telecom, and health sectors. This chapter explores ML applications across three domains namely healthcare, marketing, and telecommunications, with a primary focus on developing a framework for optimal ML algorithm selection. In healthcare, the framework addresses critical challenges such as cardiovascular disease prediction accounting for 28.1% of global deaths and fetal health classification into healthy or unhealthy states, utilizing three datasets. ML algorithms are categorized into eager, lazy, and hybrid learners, selected based on dataset attributes, performance metrics (accuracy, precision, recall), and Akaike Information Criterion (AIC) scores. For validation, eight datasets from the three sectors are employed in the experiments. The key contribution is a recommendation framework that identifies the best ML model according to input attributes, balancing performance evaluation and model complexity to enhance efficiency and accuracy in diverse real-world applications. This approach bridges gaps in automated model selection, offering practical implications for interdisciplinary ML deployment.

Security Operations Centers (SOCs) are overwhelmed by tens of thousands of daily alerts, with only a small fraction corresponding to genuine attacks. This overload creates alert fatigue, leading to overlooked threats and analyst burnout. Classical detection pipelines are brittle and context-poor, while recent LLM-based approaches typically rely on a single model to interpret logs, retrieve context, and adjudicate alerts end-to-end -- an approach that struggles with noisy enterprise data and offers limited transparency. We propose CORTEX, a multi-agent LLM architecture for high-stakes alert triage in which specialized agents collaborate over real evidence: a behavior-analysis agent inspects activity sequences, evidence-gathering agents query external systems, and a reasoning agent synthesizes findings into an auditable decision. To support training and evaluation, we release a dataset of fine-grained SOC investigations from production environments, capturing step-by-step analyst actions and linked tool outputs. Across diverse enterprise scenarios, CORTEX substantially reduces false positives and improves investigation quality over state-of-the-art single-agent LLMs.

The wide adoption of AI decision-making systems in critical domains such as criminal justice, loan approval, and hiring processes has heightened concerns about algorithmic fairness. As we often only have access to the output of algorithms without insights into their internal mechanisms, it was natural to examine how decisions would alter when auxiliary sensitive attributes (such as race) change. This led the research community to come up with counterfactual fairness measures, but how to evaluate the measure from available data remains a challenging task. In many practical applications, the target counterfactual measure is not identifiable, i.e., it cannot be uniquely determined from the combination of quantitative data and qualitative knowledge. This paper addresses this challenge using partial identification, which derives informative bounds over counterfactual fairness measures from observational data. We introduce a Bayesian approach to bound unknown counterfactual fairness measures with high confidence. We demonstrate our algorithm on the COMPAS dataset, examining fairness in recidivism risk scores with respect to race, age, and sex. Our results reveal a positive (spurious) effect on the COMPAS score when changing race to African-American (from all others) and a negative (direct causal) effect when transitioning from young to old age.

Dual-encoder retrievers depend on the principle that relevant documents should score higher than irrelevant ones for a given query. Yet the dominant Noise Contrastive Estimation (NCE) objective, which underpins Contrastive Loss, optimizes a softened ranking surrogate that we rigorously prove is fundamentally oblivious to score separation quality and unrelated to AUC. This mismatch leads to poor calibration and suboptimal performance in downstream tasks like retrieval-augmented generation (RAG). To address this fundamental limitation, we introduce the MW loss, a new training objective that maximizes the Mann-Whitney U statistic, which is mathematically equivalent to the Area under the ROC Curve (AUC). MW loss encourages each positive-negative pair to be correctly ranked by minimizing binary cross entropy over score differences. We provide theoretical guarantees that MW loss directly upper-bounds the AoC, better aligning optimization with retrieval goals. We further promote ROC curves and AUC as natural threshold free diagnostics for evaluating retriever calibration and ranking quality. Empirically, retrievers trained with MW loss consistently outperform contrastive counterparts in AUC and standard retrieval metrics. Our experiments show that MW loss is an empirically superior alternative to Contrastive Loss, yielding better-calibrated and more discriminative retrievers for high-stakes applications like RAG.

Detecting anomalies in irregularly sampled multi-variate time-series is challenging, especially in data-scarce settings. Here we introduce an anomaly detection framework for irregularly sampled time-series that leverages neural jump ordinary differential equations (NJODEs). The method infers conditional mean and variance trajectories in a fully path dependent way and computes anomaly scores. On synthetic data containing jump, drift, diffusion, and noise anomalies, the framework accurately identifies diverse deviations. Applied to infant gut microbiome trajectories, it delineates the magnitude and persistence of antibiotic-induced disruptions: revealing prolonged anomalies after second antibiotic courses, extended duration treatments, and exposures during the second year of life. We further demonstrate the predictive capabilities of the inferred anomaly scores in accurately predicting antibiotic events and outperforming diversity-based baselines. Our approach accommodates unevenly spaced longitudinal observations, adjusts for static and dynamic covariates, and provides a foundation for inferring microbial anomalies induced by perturbations, offering a translational opportunity to optimize intervention regimens by minimizing microbial disruptions.

Osteoporosis silently erodes skeletal integrity worldwide; however, early detection through imaging can prevent most fragility fractures. Artificial intelligence (AI) methods now mine routine Dual-energy X-ray Absorptiometry (DXA), X-ray, Computed Tomography (CT), and Magnetic Resonance Imaging (MRI) scans for subtle, clinically actionable markers, but the literature is fragmented. This survey unifies the field through a tri-axial framework that couples imaging modalities with clinical tasks and AI methodologies (classical machine learning, convolutional neural networks (CNNs), transformers, self-supervised learning, and explainable AI). Following a concise clinical and technical primer, we detail our Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-guided search strategy, introduce the taxonomy via a roadmap figure, and synthesize cross-study insights on data scarcity, external validation, and interpretability. By identifying emerging trends, open challenges, and actionable research directions, this review provides AI scientists, medical imaging researchers, and musculoskeletal clinicians with a clear compass to accelerate rigorous, patient-centered innovation in osteoporosis care. The project page of this survey can also be found on Github.

Sleep apnea is a serious sleep-related breathing disorder that is common and can impact health if left untreated. Currently the traditional method for screening and diagnosis is overnight polysomnography. Polysomnography is expensive and takes a lot of time, and is not practical for screening large groups of people. In this paper, we explored a more accessible option, using respiratory audio recordings to spot signs of apnea.We utilized 18 audio files.The approach involved converting breathing sounds into spectrograms, balancing the dataset by oversampling apnea segments, and applying class weights to reduce bias toward the majority class. The model reached a recall of 90.55 for apnea detection. Intentionally, prioritizing catching apnea events over general accuracy. Despite low precision,the high recall suggests potential as a low-cost screening tool that could be used at home or in basic clinical setups, potentially helping identify at-risk individuals much earlier.

Electroencephalography (EEG) interpretation using multimodal large language models (MLLMs) offers a novel approach for analyzing brain signals. However, the complex nature of brain activity introduces critical challenges: EEG signals simultaneously encode both cognitive processes and intrinsic neural states, creating a mismatch in EEG paired-data modality that hinders effective cross-modal representation learning. Through a pivot investigation, we uncover complementary relationships between these modalities. Leveraging this insight, we propose mapping EEG signals and their corresponding modalities into a unified semantic space to achieve generalized interpretation. To fully enable conversational capabilities, we further introduce WaveMind-Instruct-338k, the first cross-task EEG dataset for instruction tuning. The resulting model demonstrates robust classification accuracy while supporting flexible, open-ended conversations across four downstream tasks, thereby offering valuable insights for both neuroscience research and the development of general-purpose EEG models.

Underwater object detection is critical for monitoring marine ecosystems but poses unique challenges, including degraded image quality, imbalanced class distribution, and distinct visual characteristics. Not every species is detected equally well, yet underlying causes remain unclear. We address two key research questions: 1) What factors beyond data quantity drive class-specific performance disparities? 2) How can we systematically improve detection of under-performing marine species? We manipulate the DUO and RUOD datasets to separate the object detection task into localization and classification and investigate the under-performance of the scallop class. Localization analysis using YOLO11 and TIDE finds that foreground-background discrimination is the most problematic stage regardless of data quantity. Classification experiments reveal persistent precision gaps even with balanced data, indicating intrinsic feature-based challenges beyond data scarcity and inter-class dependencies. We recommend imbalanced distributions when prioritizing precision, and balanced distributions when prioritizing recall. Improving under-performing classes should focus on algorithmic advances, especially within localization modules. We publicly release our code and datasets.