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Decoding visual stimuli in human brain by using Anatomical Pattern Analysis on fMRI images

arXiv.org Machine Learning

A universal unanswered question in neuroscience and machine learning is whether computers can decode the patterns of the human brain. Multi-Voxels Pattern Analysis (MVPA) is a critical tool for addressing this question. However, there are two challenges in the previous MVPA methods, which include decreasing sparsity and noises in the extracted features and increasing the performance of prediction. In overcoming mentioned challenges, this paper proposes Anatomical Pattern Analysis (APA) for decoding visual stimuli in the human brain. This framework develops a novel anatomical feature extraction method and a new imbalance AdaBoost algorithm for binary classification. Further, it utilizes an Error-Correcting Output Codes (ECOC) method for multi-class prediction. APA can automatically detect active regions for each category of the visual stimuli. Moreover, it enables us to combine homogeneous datasets for applying advanced classification. Experimental studies on 4 visual categories (words, consonants, objects and scrambled photos) demonstrate that the proposed approach achieves superior performance to state-of-the-art methods.


Towards Competitive Classifiers for Unbalanced Classification Problems: A Study on the Performance Scores

arXiv.org Machine Learning

Although a great methodological effort has been invested in proposing competitive solutions to the class-imbalance problem, little effort has been made in pursuing a theoretical understanding of this matter. In order to shed some light on this topic, we perform, through a novel framework, an exhaustive analysis of the adequateness of the most commonly used performance scores to assess this complex scenario. We conclude that using unweighted H\"older means with exponent $p \leq 1$ to average the recalls of all the classes produces adequate scores which are capable of determining whether a classifier is competitive. Then, we review the major solutions presented in the class-imbalance literature. Since any learning task can be defined as an optimisation problem where a loss function, usually connected to a particular score, is minimised, our goal, here, is to find whether the learning tasks found in the literature are also oriented to maximise the previously detected adequate scores. We conclude that they usually maximise the unweighted H\"older mean with $p = 1$ (a-mean). Finally, we provide bounds on the values of the studied performance scores which guarantee a classifier with a higher recall than the random classifier in each and every class.


A machine learning system for automated whole-brain seizure detection

#artificialintelligence

Epilepsy is a chronic neurological condition that affects approximately 70 million people worldwide. Characterised by sudden bursts of excess electricity in the brain, manifesting as seizures, epilepsy is still not well understood when compared with other neurological disorders. Seizures often happen unexpectedly and attempting to predict them has been a research topic for the last 30 years. Electroencephalograms have been integral to these studies, as the recordings that they produce can capture the brain's electrical signals. The diagnosis of epilepsy is usually made by a neurologist, but can be difficult to make in the early stages.


Joint Estimation of Multiple Dependent Gaussian Graphical Models with Applications to Mouse Genomics

arXiv.org Machine Learning

Gaussian graphical models are widely used to represent conditional dependence among random variables. In this paper, we propose a novel estimator for data arising from a group of Gaussian graphical models that are themselves dependent. A motivating example is that of modeling gene expression collected on multiple tissues from the same individual: here the multivariate outcome is affected by dependencies acting not only at the level of the specific tissues, but also at the level of the whole body; existing methods that assume independence among graphs are not applicable in this case. To estimate multiple dependent graphs, we decompose the problem into two graphical layers: the systemic layer, which affects all outcomes and thereby induces cross- graph dependence, and the category-specific layer, which represents graph-specific variation. We propose a graphical EM technique that estimates both layers jointly, establish estimation consistency and selection sparsistency of the proposed estimator, and confirm by simulation that the EM method is superior to a simple one-step method. We apply our technique to mouse genomics data and obtain biologically plausible results.


Robust and Sparse Regression via $\gamma$-divergence

arXiv.org Machine Learning

In high-dimensional data, many sparse regression methods have been proposed. However, they may not be robust against outliers. Recently, the use of density power weight has been studied for robust parameter estimation and the corresponding divergences have been discussed. One of such divergences is the $\gamma$-divergence and the robust estimator using the $\gamma$-divergence is known for having a strong robustness. In this paper, we consider the robust and sparse regression based on $\gamma$-divergence. We extend the $\gamma$-divergence to the regression problem and show that it has a strong robustness under heavy contamination even when outliers are heterogeneous. The loss function is constructed by an empirical estimate of the $\gamma$-divergence with sparse regularization and the parameter estimate is defined as the minimizer of the loss function. To obtain the robust and sparse estimate, we propose an efficient update algorithm which has a monotone decreasing property of the loss function. Particularly, we discuss a linear regression problem with $L_1$ regularization in detail. In numerical experiments and real data analyses, we see that the proposed method outperforms past robust and sparse methods.


TragiComedy hour: P-values vs posterior probabilities vs diagnostic error rates

#artificialintelligence

The consequences of recent criticisms of statistical tests have breathed brand new life into some very old howlers, many of which have been discussed on this blog. What is not funny, though, is how standard notions such as frequentist error probabilities are being redefined in the process, and how we now have arguments built on equivocations. In fact, there are official guidebooks for the statistically perplexed giving inconsistent definitions to the same term (See for just 1 of many examples this post). How much more perplexed will that leave us! Since it's near the 5-year anniversary of this blog, tonight let's listen in to a new comedy hour mixing one from 3 years ago with some add-ons*.


Cutpurse capers

#artificialintelligence

SMART-CARD public-transport ticketing systems let people hop between buses, subways, trams, surface rail and river boats--even when these are operated by different companies--without having to buy new tickets. This undoubted good, though, has ramifications. One is that anyone with access can, by following individual passengers (or, at least, their cards), study precisely where people are going. Companies use this knowledge to optimise services--again, an undoubted good. But many other things, some disturbing to freedom lovers, might also be done with smart-card data.


Random Forest for Label Ranking

arXiv.org Machine Learning

Label ranking aims to learn a mapping from instances to rankings over a finite number of predefined labels. Random forest is a powerful and one of the most successfully general-purpose machine learning algorithms of modern times. In the literature, there seems no research has yet been done in applying random forest to label ranking. In this paper, We present a powerful random forest label ranking method which uses random decision trees to retrieve nearest neighbors that are not only similar in the feature space but also in the ranking space. We have developed a novel two-step rank aggregation strategy to effectively aggregate neighboring rankings discovered by the random forest into a final predicted ranking. Compared with existing methods, the new random forest method has many advantages including its intrinsically scalable tree data structure, highly parallel-able computational architecture and much superior performances. We present extensive experimental results to demonstrate that our new method achieves the best predictive accuracy performances compared with state-of-the-art methods for datasets with complete ranking and datasets with only partial ranking information.


Learning Temporal Dependence from Time-Series Data with Latent Variables

arXiv.org Machine Learning

We consider the setting where a collection of time series, modeled as random processes, evolve in a causal manner, and one is interested in learning the graph governing the relationships of these processes. A special case of wide interest and applicability is the setting where the noise is Gaussian and relationships are Markov and linear. We study this setting with two additional features: firstly, each random process has a hidden (latent) state, which we use to model the internal memory possessed by the variables (similar to hidden Markov models). Secondly, each variable can depend on its latent memory state through a random lag (rather than a fixed lag), thus modeling memory recall with differing lags at distinct times. Under this setting, we develop an estimator and prove that under a genericity assumption, the parameters of the model can be learned consistently. We also propose a practical adaption of this estimator, which demonstrates significant performance gains in both synthetic and real-world datasets.


A Meta-Analysis of the Anomaly Detection Problem

arXiv.org Artificial Intelligence

This article provides a thorough meta-analysis of the anomaly detection problem. To accomplish this we first identify approaches to benchmarking anomaly detection algorithms across the literature and produce a large corpus of anomaly detection benchmarks that vary in their construction across several dimensions we deem important to real-world applications: (a) point difficulty, (b) relative frequency of anomalies, (c) clusteredness of anomalies, and (d) relevance of features. We apply a representative set of anomaly detection algorithms to this corpus, yielding a very large collection of experimental results. We analyze these results to understand many phenomena observed in previous work. First we observe the effects of experimental design on experimental results. Second, results are evaluated with two metrics, ROC Area Under the Curve and Average Precision. We employ statistical hypothesis testing to demonstrate the value (or lack thereof) of our benchmarks. We then offer several approaches to summarizing our experimental results, drawing several conclusions about the impact of our methodology as well as the strengths and weaknesses of some algorithms. Last, we compare results against a trivial solution as an alternate means of normalizing the reported performance of algorithms. The intended contributions of this article are many; in addition to providing a large publicly-available corpus of anomaly detection benchmarks, we provide an ontology for describing anomaly detection contexts, a methodology for controlling various aspects of benchmark creation, guidelines for future experimental design and a discussion of the many potential pitfalls of trying to measure success in this field.