A daunting challenge faced by environmental regulators in the U.S. and other countries is the requirement that they evaluate the potential toxicity of a large number of unique chemicals that are currently in common use (in the range of 10,000–30,000) but for which little toxicology information is available. The time and cost required for traditional toxicity testing approaches, coupled with the desire to reduce animal use is driving the search for new toxicity prediction methods [1–3]. Several efforts are starting to address this information gap by using relatively inexpensive, high throughput screening approaches in order to link chemical and biological space [1, 4–21]. The U.S. EPA is carrying out one such large screening and prioritization experiment, called ToxCast, whose goal is to develop predictive signatures or classifiers that can accurately predict whether a given chemical will or will not cause particular toxicities [4]. This program is investigating a variety of chemically-induced toxicity endpoints including developmental and reproductive toxicity, neurotoxicity and cancer.

Google's taken a small step towards addressing the persistent problem of bias in artificial intelligence, setting its boffins to work on equal-opportunity smile detection. In a paper published at arXiv December 1, Mountain View trio Hee Jung Ryu, Margaret Mitchell and Hartwig Adam laid out the results of research designed to handle the twin problems of gender and race diversity when machine learning is applied to images. Biased models have become a contentious issue in AI over the course of the year, with study after study documenting both the extent of algorithmic bias, and the real-life impacts such as women seeing ads for low-paying jobs and African-Americans being sent more ads about being arrested. In spite of this, researchers are still comfortable making phrenology-like claims about identifying criminal faces, or believing that their AI can spot beautiful women. Google's authors agreed that bias is an issue, and wrote "users have noticed a troubling gap between how well some demographics are recognised compared with others".

The rising interest in pattern recognition and data analytics has spurred the development of innovative machine learning algorithms and tools. However, as each algorithm has its strengths and limitations, one is motivated to judiciously fuse multiple algorithms in order to find the "best" performing one, for a given dataset. Ensemble learning aims at such high-performance meta-algorithm, by combining the outputs from multiple algorithms. The present work introduces a blind scheme for learning from ensembles of classifiers, using a moment matching method that leverages joint tensor and matrix factorization. Blind refers to the combiner who has no knowledge of the ground-truth labels that each classifier has been trained on. A rigorous performance analysis is derived and the proposed scheme is evaluated on synthetic and real datasets.

We present a framework for analyzing the exact dynamics of a class of online learning algorithms in the high-dimensional scaling limit. Our results are applied to two concrete examples: online regularized linear regression and principal component analysis. As the ambient dimension tends to infinity, and with proper time scaling, we show that the time-varying joint empirical measures of the target feature vector and its estimates provided by the algorithms will converge weakly to a deterministic measured-valued process that can be characterized as the unique solution of a nonlinear PDE. Numerical solutions of this PDE can be efficiently obtained. These solutions lead to precise predictions of the performance of the algorithms, as many practical performance metrics are linear functionals of the joint empirical measures. In addition to characterizing the dynamic performance of online learning algorithms, our asymptotic analysis also provides useful insights. In particular, in the high-dimensional limit, and due to exchangeability, the original coupled dynamics associated with the algorithms will be asymptotically "decoupled", with each coordinate independently solving a 1-D effective minimization problem via stochastic gradient descent. Exploiting this insight for nonconvex optimization problems may prove an interesting line of future research.

Environmental acoustic sensing involves the retrieval and processing of audio signals to better understand our surroundings. While large-scale acoustic data make manual analysis infeasible, they provide a suitable playground for machine learning approaches. Most existing machine learning techniques developed for environmental acoustic sensing do not provide flexible control of the trade-off between the false positive rate and the false negative rate. This paper presents a cost-sensitive classification paradigm, in which the hyper-parameters of classifiers and the structure of variational autoencoders are selected in a principled Neyman-Pearson framework. We examine the performance of the proposed approach using a dataset from the HumBug project which aims to detect the presence of mosquitoes using sound collected by simple embedded devices.

Count-based exploration algorithms are known to perform near-optimally when used in conjunction with tabular reinforcement learning (RL) methods for solving small discrete Markov decision processes (MDPs). It is generally thought that count-based methods cannot be applied in high-dimensional state spaces, since most states will only occur once. Recent deep RL exploration strategies are able to deal with high-dimensional continuous state spaces through complex heuristics, often relying on optimism in the face of uncertainty or intrinsic motivation. In this work, we describe a surprising finding: a simple generalization of the classic count-based approach can reach near state-of-the-art performance on various high-dimensional and/or continuous deep RL benchmarks. States are mapped to hash codes, which allows to count their occurrences with a hash table. These counts are then used to compute a reward bonus according to the classic count-based exploration theory. We find that simple hash functions can achieve surprisingly good results on many challenging tasks. Furthermore, we show that a domain-dependent learned hash code may further improve these results. Detailed analysis reveals important aspects of a good hash function: 1) having appropriate granularity and 2) encoding information relevant to solving the MDP. This exploration strategy achieves near state-of-the-art performance on both continuous control tasks and Atari 2600 games, hence providing a simple yet powerful baseline for solving MDPs that require considerable exploration.

Sequence-to-sequence models, such as attention-based models in automatic speech recognition (ASR), are typically trained to optimize the cross-entropy criterion which corresponds to improving the log-likelihood of the data. However, system performance is usually measured in terms of word error rate (WER), not log-likelihood. Traditional ASR systems benefit from discriminative sequence training which optimizes criteria such as the state-level minimum Bayes risk (sMBR) which are more closely related to WER. In the present work, we explore techniques to train attention-based models to directly minimize expected word error rate. We consider two loss functions which approximate the expected number of word errors: either by sampling from the model, or by using N-best lists of decoded hypotheses, which we find to be more effective than the sampling-based method. In experimental evaluations, we find that the proposed training procedure improves performance by up to 8.2% relative to the baseline system. This allows us to train grapheme-based, uni-directional attention-based models which match the performance of a traditional, state-of-the-art, discriminative sequence-trained system on a mobile voice-search task.

Mosquitoes are a major vector for malaria, causing hundreds of thousands of deaths in the developing world each year. Not only is the prevention of mosquito bites of paramount importance to the reduction of malaria transmission cases, but understanding in more forensic detail the interplay between malaria, mosquito vectors, vegetation, standing water and human populations is crucial to the deployment of more effective interventions. Typically the presence and detection of malaria-vectoring mosquitoes is only quantified by hand-operated insect traps or signified by the diagnosis of malaria. If we are to gather timely, large-scale data to improve this situation, we need to automate the process of mosquito detection and classification as much as possible. In this paper, we present a candidate mobile sensing system that acts as both a portable early warning device and an automatic acoustic data acquisition pipeline to help fuel scientific inquiry and policy. The machine learning algorithm that powers the mobile system achieves excellent off-line multi-species detection performance while remaining computationally efficient. Further, we have conducted preliminary live mosquito detection tests using low-cost mobile phones and achieved promising results. The deployment of this system for field usage in Southeast Asia and Africa is planned in the near future. In order to accelerate processing of field recordings and labelling of collected data, we employ a citizen science platform in conjunction with automated methods, the former implemented using the Zooniverse platform, allowing crowdsourcing on a grand scale.

The challenge of text classification is to attach labels to bodies of text, e.g., tax document, medical form, etc. based on the text itself. For example, think of your spam folder in your email. How does your email provider know that a particular message is spam or "ham" (not spam)? We'll take a look at one natural language processing technique for text classification called Naive Bayes. Let's take a second to break this down. On the left, we have the probability of an event happening given that event happens.

This paper examines the speaker identification potential of breath sounds in continuous speech. Speech is largely produced during exhalation. In order to replenish air in the lungs, speakers must periodically inhale. When inhalation occurs in the midst of continuous speech, it is generally through the mouth. Intra-speech breathing behavior has been the subject of much study, including the patterns, cadence, and variations in energy levels. However, an often ignored characteristic is the {\em sound} produced during the inhalation phase of this cycle. Intra-speech inhalation is rapid and energetic, performed with open mouth and glottis, effectively exposing the entire vocal tract to enable maximum intake of air. This results in vocal tract resonances evoked by turbulence that are characteristic of the speaker's speech-producing apparatus. Consequently, the sounds of inhalation are expected to carry information about the speaker's identity. Moreover, unlike other spoken sounds which are subject to active control, inhalation sounds are generally more natural and less affected by voluntary influences. The goal of this paper is to demonstrate that breath sounds are indeed bio-signatures that can be used to identify speakers. We show that these sounds by themselves can yield remarkably accurate speaker recognition with appropriate feature representations and classification frameworks.