Statistical literacy (assessing statistical statements, arguments and associations) is extremely important for producing and interpreting results from data analysis, yet it usually isn't a part of mainstream statistics education [1]. From the correlation-causation error to immortal time bias, there are many ways to invalidate your results. You can lessen the odds by following a few good practices. When you design your analysis, make sure you're asking the right question. This isn't always easy, as the German Federal Ministry of the Interior, Building and Home Affairs found out after publishing a 2018 press release concerning the "successful" use of facial recognition technology at train stations [2].

Data are not only ubiquitous in society, but are increasingly complex both in size and dimensionality. Dimension reduction offers researchers and scholars the ability to make such complex, high dimensional data spaces simpler and more manageable. This Element offers readers a suite of modern unsupervised dimension reduction techniques along with hundreds of lines of R code, to efficiently represent the original high dimensional data space in a simplified, lower dimensional subspace. Launching from the earliest dimension reduction technique principal components analysis and using real social science data, I introduce and walk readers through application of the following techniques: locally linear embedding, t-distributed stochastic neighbor embedding (t-SNE), uniform manifold approximation and projection, self-organizing maps, and deep autoencoders. The result is a well-stocked toolbox of unsupervised algorithms for tackling the complexities of high dimensional data so common in modern society. All code is publicly accessible on Github.

We propose a distributionally robust support vector machine with a fairness constraint that encourages the classifier to be fair in view of the equality of opportunity criterion. We use a type-$\infty$ Wasserstein ambiguity set centered at the empirical distribution to model distributional uncertainty and derive an exact reformulation for worst-case unfairness measure. We establish that the model is equivalent to a mixed-binary optimization problem, which can be solved by standard off-the-shelf solvers. We further prove that the expectation of the hinge loss objective function constitutes an upper bound on the misclassification probability. Finally, we numerically demonstrate that our proposed approach improves fairness with negligible loss of predictive accuracy.

Classical network embeddings create a low dimensional representation of the learned relationships between features across nodes. Such embeddings are important for tasks such as link prediction and node classification. In the current paper, we consider low dimensional embeddings of dynamic networks, that is a family of time varying networks where there exist both temporal and spatial link relationships between nodes. We present novel embedding methods for a dynamic network based on higher order tensor decompositions for tensorial representations of the dynamic network. In one sense, our embeddings are analogous to spectral embedding methods for static networks. We provide a rationale for our algorithms via a mathematical analysis of some potential reasons for their effectiveness. Finally, we demonstrate the power and efficiency of our approach by comparing our algorithms' performance on the link prediction task against an array of current baseline methods across three distinct real-world dynamic networks.

Multi-label classification of chest X-ray images is frequently performed using discriminative approaches, i.e. learning to map an image directly to its binary labels. Such approaches make it challenging to incorporate auxiliary information such as annotation uncertainty or a dependency among the labels. Building towards this, we propose a novel knowledge graph reformulation of multi-label classification, which not only readily increases predictive performance of an encoder but also serves as a general framework for introducing new domain knowledge. Specifically, we construct a multi-modal knowledge graph out of the chest X-ray images and its labels and pose multi-label classification as a link prediction problem. Incorporating auxiliary information can then simply be achieved by adding additional nodes and relations among them. When tested on a publicly-available radiograph dataset (CheXpert), our relational-reformulation using a naive knowledge graph outperforms the state-of-art by achieving an area-under-ROC curve of 83.5%, an improvement of "sim 1" over a purely discriminative approach.

For many psychiatric disorders, neuroimaging offers a potential for revolutionizing diagnosis and treatment by providing access to preverbal mental processes. In their study "Machine learning of neural representations of suicide and emotion concepts identifies suicidal youth."1, Just and colleagues report that a Naive Bayes classifier, trained on voxelwise fMRI responses in human participants during the presentation of words and concepts related to mortality, can predict whether an individual had reported having suicidal ideations with a classification accuracy of 91%. Here we report a reappraisal of the methods employed by the authors, including re-analysis of the same data set, that calls into question the accuracy of the authors findings.

Several pieces of work have uncovered performance disparities by conducting "disaggregated evaluations" of AI systems. We build on these efforts by focusing on the choices that must be made when designing a disaggregated evaluation, as well as some of the key considerations that underlie these design choices and the tradeoffs between these considerations. We argue that a deeper understanding of the choices, considerations, and tradeoffs involved in designing disaggregated evaluations will better enable researchers, practitioners, and the public to understand the ways in which AI systems may be underperforming for particular groups of people.

Although automated pathology classification using deep learning (DL) has proved to be predictively efficient, DL methods are found to be data and compute cost intensive. In this work, we aim to reduce DL training costs by pre-training a Resnet feature extractor using SimCLR contrastive loss for latent encoding of OCT images. We propose a novel active learning framework that identifies a minimal sub-sampled dataset containing the most uncertain OCT image samples using label propagation on the SimCLR latent encodings. The pre-trained Resnet model is then fine-tuned with the labelled minimal sub-sampled data and the underlying pathological sites are visually explained. Our framework identifies upto 2% of OCT images to be most uncertain that need prioritized specialist attention and that can fine-tune a Resnet model to achieve upto 97% classification accuracy. The proposed method can be extended to other medical images to minimize prediction costs.

Along with the Coronavirus pandemic, another crisis has manifested itself in the form of mass fear and panic phenomena, fueled by incomplete and often inaccurate information. There is therefore a tremendous need to address and better understand COVID-19’s informational crisis and gauge public sentiment, so that appropriate messaging and policy decisions can be implemented. In this research article, we identify public sentiment associated with the pandemic using Coronavirus specific Tweets and R statistical software, along with its sentiment analysis packages. We demonstrate insights into the progress of fear-sentiment over time as COVID-19 approached peak levels in the United States, using descriptive textual analytics supported by necessary textual data visualizations. Furthermore, we provide a methodological overview of two essential machine learning (ML) classification methods, in the context of textual analytics, and compare their effectiveness in classifying Coronavirus Tweets of varying lengths. We observe a strong classification accuracy of 91% for short Tweets, with the Naïve Bayes method. We also observe that the logistic regression classification method provides a reasonable accuracy of 74% with shorter Tweets, and both methods showed relatively weaker performance for longer Tweets. This research provides insights into Coronavirus fear sentiment progression, and outlines associated methods, implications, limitations and opportunities.

Medical systems in general, and patient treatment decisions and outcomes in particular, are affected by bias based on gender and other demographic elements. As language models are increasingly applied to medicine, there is a growing interest in building algorithmic fairness into processes impacting patient care. Much of the work addressing this question has focused on biases encoded in language models -- statistical estimates of the relationships between concepts derived from distant reading of corpora. Building on this work, we investigate how word choices made by healthcare practitioners and language models interact with regards to bias. We identify and remove gendered language from two clinical-note datasets and describe a new debiasing procedure using BERT-based gender classifiers. We show minimal degradation in health condition classification tasks for low- to medium-levels of bias removal via data augmentation. Finally, we compare the bias semantically encoded in the language models with the bias empirically observed in health records. This work outlines an interpretable approach for using data augmentation to identify and reduce the potential for bias in natural language processing pipelines.